The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Blood Cell MicroRNAs: What Are They and What Future Do They Hold?
Abstract
The advent of blood component storage revolutionized health care by allowing for a managed supply of transfusion quality blood products. During storage, blood components undergo a series of physiological changes that affect the product quality, which ultimately can interfere with the safety and efficacy of such products after transfusion. Despite continuous improvements in blood component quality and safety, it is still desirable to have in vitro standard markers of measurable characteristics that predict blood component safety and efficacy in vivo following their transfusion. Over the last decade, research on the feasibility of using microRNAs as biomarkers for various clinical manifestations and cellular pathologies has exploded. Here, we review the literature on blood cell microRNAs and discuss the potential of these molecules to act as measurable characteristics (product biomarkers) for stored blood component quality and safety.
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“Interestingly, many miRNAs that are up- or downregulated during erythropoiesis may not be removed or degraded but selectively retained in mature red blood cells (RBCs)”
From Red Blood Cells as Potential Repositories of MicroRNAs in the Circulatory System (2020) · cites this paper as Ryan and Atreya, 2011
In the citing paper
“MiRNAs in erythrocytes have a very unique expression pattern compared with human reticulocytes, which indicates that miRNAs are likely selectively retained and function in mature RBCs”
From Red Blood Cells as Potential Repositories of MicroRNAs in the Circulatory System (2020) · cites this paper as Ryan and Atreya, 2011
In the citing paper
“which indicates that miRNAs are likely selectively retained and function in mature RBCs”
From Red Blood Cells as Potential Repositories of MicroRNAs in the Circulatory System (2020) · cites this paper as Ryan and Atreya, 2011
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Cited by
Sorted by citations
Red Blood Cells as Potential Repositories of MicroRNAs in the Circulatory System
Sun, L., Yu, Y., Niu, B., & Wang, D. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00442 · Cited by 83
Metadata
- Authors
- Ryan, P., & Atreya, C.
- Venue
- Transfusion Medicine Reviews
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 25
- Issue
- 3
- Pages
- 247-251
- ISSN
- 0887-7963
- Cited by
- 21
- References
- 1
- Language
- en
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