Cited by 220Evolution and Genetic DynamicsChromosomal and Genetic VariationsGenetic diversity and population structure

The polymorphic prelude to Bateson–Dobzhansky–Muller incompatibilities

Cutter, Asher D.·2012·Trends in Ecology & Evolution

Abstract

Speciation research has largely assumed that the genetic causes of reproductive isolation are the work of fixed, divergent alleles that interact to cause genetic problems in hybrids: Bateson-Dobzhansky-Muller incompatibilities. However, many recent studies demonstrate substantial heritable polymorphism within species for hybrid incompatibility, herein called variable reproductive isolation (VRI). In this review, I outline the causes and importance of this general phenomenon. I also identify the new challenges of quantifying the relative contributions to reproductive isolation of fixed alleles versus polymorphisms, and the change in these contributions over the course of speciation. Explicit integration of VRI into speciation theory will help to quantify the relative roles of genetic drift and selection in speciation, but this synthesis requires substantial new contributions from both theory and empirical studies.

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Crossref · 10.1016/j.tree.2011.11.004

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Authors
Cutter, A. D.
Affiliations
University of Toronto (CA)
Corresponding author
Cutter, Asher D.
Venue
Trends in Ecology & Evolution
Publisher
Elsevier BV
Published
2012-04
Volume
27
Issue
4
Pages
209-218
ISSN
0169-5347 (ISSN-L)
OpenAlex
W1974240519
Cited by
220
References
107
Citations by year
2026: 9 · 2025: 11 · 2024: 18 · 2023: 13 · 2022: 14 · 2021: 13 · 2020: 16 · 2019: 16 · 2018: 7 · 2017: 37 · 2016: 18 · 2015: 13 · 2014: 18 · 2013: 11 · 2012: 4
FWCI
1.14
Type
journal article
Language
en
Open access
closed
Locations
  • Trends in Ecology & Evolution (publishedVersion)
  • PubMed (publishedVersion)
Funders
Natural Sciences and Engineering Research Council of Canada
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Chromosomal and Genetic Variations
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
Keywords
hybrid incompatibility, speciation, reproductive isolation, genetic drift, natural selection, speciation theory
MeSH terms
Alleles, Animals, Models, Theoretical, Plants, Polymorphism, Genetic

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