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Association of E6AP (UBE3A) with human papillomavirus type 11 E6 protein
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“high-risk E6 binds to an LXXLL motif on a cellular E3 ubiquitin-protein ligase, E6-associated protein (E6AP) [166,167,168,169], forming the E6-E6AP complex, which recruits and ubiquitinates p53, mediating its degradation via the proteasome [170,171,172]”
From The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis (2021) · cites this paper as [169]
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Cited by
Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins
Rozenblatt-Rosen, O., Deo, R. C., Padi, M., Adelmant, G., Calderwood, M. A., Rolland, T., Grace, M., Dricot, A., Askenazi, M., Tavares, M., et al. (2012) · Nature · doi:10.1038/nature11288 · Cited by 378
White, E. A., Kramer, R. E., Tan, M. J. A., Hayes, S. D., Harper, J. W., & Howley, P. M. (2012) · Journal of Virology · doi:10.1128/jvi.02172-12 · Cited by 198
Basukala, O., & Banks, L. (2021) · Viruses · doi:10.3390/v13101892 · Cited by 137
Metadata
- Authors
- Brimer, N., Lyons, C., & Vande Pol, S. B.
- Venue
- Virology
- Publisher
- Elsevier BV
- Published
- 2007-02
- Volume
- 358
- Issue
- 2
- Pages
- 303-310
- ISSN
- 0042-6822
- Cited by
- 70
- References
- 2
- Language
- en
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- Brimer, N., Lyons, C., & Vande Pol, S. B. (2007). Association of E6AP (UBE3A) with human papillomavirus type 11 E6 protein. Virology. https://doi.org/10.1016/j.virol.2006.08.038