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Human papillomavirus type 16 E5-mediated upregulation of Met in human keratinocytes
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“activation of EGFR signalling by HPV-16 E5 has also been linked to the activation of the c-Met growth factor receptor, a potent oncogene that contributes to the motility of HPV-containing cells [218]”
From The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis (2021) · cites this paper as [218]
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Citations
Cites
Regulatory networks defining EMT during cancer initiation and progression
Craene, B. D., & Berx, G. (2013) · Nature Reviews Cancer · doi:10.1038/nrc3447 · Cited by 2,487
Carcinoma‐associated fibroblasts: Non‐neoplastic tumour‐promoting mesenchymal cells
Polanska, U. M., & Orimo, A. (2013) · Journal of Cellular Physiology · doi:10.1002/jcp.24347 · Cited by 208
Research works printed but not linked: 78
- Accornero, 2012, Met receptor acts uniquely for survival and morphogenesis of EGFR-dependent normal mammary epithelial and cancer cells, PLoS One, 7, e44982, 10.1371/journal.pone.0044982 · DOI
- Baker, 1987, Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines, J. Virol., 61, 962, 10.1128/jvi.61.4.962-971.1987 · DOI
- Barbaresi, 2010, Effects of human papillomavirus type 16 E5 deletion mutants on epithelial morphology: functional characterization of each transmembrane domain, J. Gen. Virol., 91, 521, 10.1099/vir.0.016295-0 · DOI
- Baykal, 2003, Overexpression of the c-Met/HGF receptor and its prognostic significance in uterine cervix carcinomas, Gynecol. Oncol., 88, 123, 10.1016/S0090-8258(02)00073-2 · DOI
- Bergstrom, 2000, Epidermal growth factor receptor signaling activates met in human anaplastic thyroid carcinoma cells, Exp. Cell Res., 259, 293, 10.1006/excr.2000.4967 · DOI
- Boccaccio, 2006, Invasive growth: a MET-driven genetic programme for cancer and stem cells, Nat. Rev. Cancer, 6, 637, 10.1038/nrc1912 · DOI
- Bodily, 2013, Regulation of the human papillomavirus type 16 late promoter by E7 and the cell cycle, Virology, 443, 11, 10.1016/j.virol.2013.04.033 · DOI
- Bodily, 2011, The E7 open reading frame acts in cis and in trans to mediate differentiation-dependent activities in the human papillomavirus type 16 life cycle, J. Virol., 85, 8852, 10.1128/JVI.00664-11 · DOI
- Bodily, 2011, Human papillomavirus E7 enhances hypoxia-inducible factor 1-mediated transcription by inhibiting binding of histone deacetylases, Cancer Res., 71, 1187, 10.1158/0008-5472.CAN-10-2626 · DOI · Paper page
- Bonine-Summers, 2007, Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells, Cancer Biol. Ther., 6, 561, 10.4161/cbt.6.4.3851 · DOI
- Caberg, 2008, Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes, Carcinogenesis, 29, 1441, 10.1093/carcin/bgn145 · DOI
- Charette, 2007, The E7 protein from human papillomavirus type 16 enhances keratinocyte migration in an Akt-dependent manner, Oncogene, 26, 7386, 10.1038/sj.onc.1210541 · DOI
- Cheng, 2012, The role of human papillomavirus type 16 E6/E7 oncoproteins in cervical epithelial-mesenchymal transition and carcinogenesis, Oncol. Lett., 3, 667, 10.3892/ol.2011.512 · DOI
- Cheung, 2013, Virological characteristics of cervical cancers carrying pure episomal form of HPV16 genome, Gynecol. Oncol., 131, 374, 10.1016/j.ygyno.2013.08.026 · DOI
- Chmielowiec, 2007, c-Met is essential for wound healing in the skin, J. Cell Biol., 177, 151, 10.1083/jcb.200701086 · DOI
- Cirri, 2012, Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression, Cancer Metastas. Rev., 31, 195, 10.1007/s10555-011-9340-x · DOI
- D'Costa, 2012, Transcriptional repression of E-cadherin by human papillomavirus type 16 E6, PLoS One, 7, e48954, 10.1371/journal.pone.0048954 · DOI · Paper page
- den Boon, 2015, Molecular transitions from papillomavirus infection to cervical precancer and cancer: role of stromal estrogen receptor signaling, Proc. Natl. Acad. Sci. USA, 112, E3255, 10.1073/pnas.1509322112 · DOI
- Dimaio, 2013, The E5 proteins, Virology, 445, 99, 10.1016/j.virol.2013.05.006 · DOI
- Doorbar, 2015, Human papillomavirus molecular biology and disease association, Rev. Med. Virol., 25, 2, 10.1002/rmv.1822 · DOI
- Doorbar, 2012, The biology and life-cycle of human papillomaviruses, Vaccine, 30, F55, 10.1016/j.vaccine.2012.06.083 · DOI
- Drake, 2014, Tumour suppressor gene function in carcinoma-associated fibroblasts: from tumour cells via EMT and back again?, J. Pathol., 232, 283, 10.1002/path.4298 · DOI
- Duffy, 2003, Microarray analysis identifies differentiation-associated genes regulated by human papillomavirus type 16 E6, Virology, 314, 196, 10.1016/S0042-6822(03)00390-8 · DOI
- Egawa, 2017, The low-risk papillomaviruses, Virus Res., 231, 119, 10.1016/j.virusres.2016.12.017 · DOI
- Faghihloo, 2016, Transcriptional regulation of E-cadherin and oncoprotein E7 by valproic acid in HPV positive cell lines, Iran. J. Basic Med. Sci., 19, 601
- Fehrmann, 2003, Human papillomavirus type 31 E5 protein supports cell cycle progression and activates late viral functions upon epithelial differentiation, J. Virol., 77, 2819, 10.1128/JVI.77.5.2819-2831.2003 · DOI
- Gambarotta, 1996, Ets up-regulates MET transcription, Oncogene, 13, 1911
- Geiger, 2008, Anomalous features of EMT during keratinocyte transformation, PLoS One, 3, e1574, 10.1371/journal.pone.0001574 · DOI
- Genther, 2003, Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle, J. Virol., 77, 2832, 10.1128/JVI.77.5.2832-2842.2003 · DOI
- Genther Williams, 2005, Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene, Cancer Res., 65, 6534, 10.1158/0008-5472.CAN-05-0083 · DOI · Paper page
- Gherardi, 2012, Targeting MET in cancer: rationale and progress, Nat. Rev. Cancer, 12, 89, 10.1038/nrc3205 · DOI
- Gius, 2007, Profiling microdissected epithelium and stroma to model genomic signatures for cervical carcinogenesis accommodating for covariates, Cancer Res., 67, 7113, 10.1158/0008-5472.CAN-07-0260 · DOI
- Greco, 2011, Human papillomavirus 16 E5 modulates the expression of host microRNAs, PLoS One, 6, e21646, 10.1371/journal.pone.0021646 · DOI
- Hanahan, 2011, Hallmarks of cancer: the next generation, Cell, 144, 646, 10.1016/j.cell.2011.02.013 · DOI · Paper page
- Hellner, 2009, HPV16 E7 oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesenchymal transition, Virology, 391, 57, 10.1016/j.virol.2009.05.036 · DOI · Paper page
- Howie, 2009, Papillomavirus E6 proteins, Virology, 384, 324, 10.1016/j.virol.2008.11.017 · DOI
- Hsieh, 2000, Sequence variants and functional analysis of human papillomavirus type 16 E5 gene in clinical specimens, Arch. Virol., 145, 2273, 10.1007/s007050070020 · DOI
- Hwang, 2011, Wild-type p53 controls cell motility and invasion by dual regulation of MET expression, Proc. Natl. Acad. Sci. USA, 108, 14240, 10.1073/pnas.1017536108 · DOI
- Jung, 2013, A novel function of HPV16-E6/E7 in epithelial-mesenchymal transition, Biochem. Biophys. Res. Commun., 435, 339, 10.1016/j.bbrc.2013.04.060 · DOI
- Kankuri, 2005, Induction of hepatocyte growth factor/scatter factor by fibroblast clustering directly promotes tumor cell invasiveness, Cancer Res., 65, 9914, 10.1158/0008-5472.CAN-05-1559 · DOI
- Klingelhutz, 2012, Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk viruses, Virology, 424, 77, 10.1016/j.virol.2011.12.018 · DOI
- Kristiansen, 1994, Coexistence of episomal and integrated HPV16 DNA in squamous cell carcinoma of the cervix, J. Clin. Pathol., 47, 253, 10.1136/jcp.47.3.253 · DOI
- Latorre, 2005, Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells, J. Cell Sci., 118, 4283, 10.1242/jcs.02560 · DOI
- Lee, 2008, Epithelial-mesenchymal transition in cervical cancer: correlation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation, Clin. Cancer Res., 14, 4743, 10.1158/1078-0432.CCR-08-0234 · DOI
- Liao, 2013, Human papillomavirus 16/18 E5 promotes cervical cancer cell proliferation, migration and invasion in vitro and accelerates tumor growth in vivo, Oncol. Rep., 29, 95, 10.3892/or.2012.2106 · DOI
- Lopes-Bastos, 2016, Tumour-endothelial cell communications: important and indispensable mediators of tumour angiogenesis, Anticancer Res., 36, 1119
- Matsumoto, 2006, Hepatocyte growth factor and the Met system as a mediator of tumor-stromal interactions, Int. J. Cancer, 119, 477, 10.1002/ijc.21808 · DOI
- Maufort, 2010, A role for HPV16 E5 in cervical carcinogenesis, Cancer Res., 70, 2924, 10.1158/0008-5472.CAN-09-3436 · DOI · Paper page
- McBride, 2017, The role of integration in oncogenic progression of HPV-associated cancers, PLoS Pathog., 13, e1006211, 10.1371/journal.ppat.1006211 · DOI · Paper page
- Moody, 2010, Human papillomavirus oncoproteins: pathways to transformation, Nat. Rev., 10, 550, 10.1038/nrc2886 · DOI
- Munger, 2004, Mechanisms of human papillomavirus-induced oncogenesis, J. Virol., 78, 11451, 10.1128/JVI.78.21.11451-11460.2004 · DOI · Paper page
- Myong, 2012, Loss of E-cadherin and acquisition of vimentin in epithelial-mesenchymal transition are notable indicators of uterine cervix cancer progression, Korean J. Pathol., 46, 341, 10.4132/KoreanJPathol.2012.46.4.341 · DOI
- Nakamura, 2009, Hypoxia-specific stabilization of HIF-1alpha by human papillomaviruses, Virology, 387, 442, 10.1016/j.virol.2009.02.036 · DOI
- Nees, 2000, Human papillomavirus type 16 E6 and E7 proteins inhibit differentiation-dependent expression of transforming growth factor-beta2 in cervical keratinocytes, Cancer Res., 60, 4289
- Parkin, 2006, Chapter 2: The burden of HPV-related cancers, Vaccine, 24, S11, 10.1016/j.vaccine.2006.05.111 · DOI
- Patel, 1999, The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300, EMBO J., 18, 5061, 10.1093/emboj/18.18.5061 · DOI · Paper page
- Pett, 2007, Integration of high-risk human papillomavirus: a key event in cervical carcinogenesis?, J. Pathol., 212, 356, 10.1002/path.2192 · DOI
- Pim, 2002, Chimaeric HPV E6 proteins allow dissection of the proteolytic pathways regulating different E6 cellular target proteins, Oncogene, 21, 8140, 10.1038/sj.onc.1206026 · DOI
- Roman, 2013, The papillomavirus E7 proteins, Virology, 445, 138, 10.1016/j.virol.2013.04.013 · DOI
- Sahab, 2012, Quantitative measurement of human papillomavirus type 16 E5 oncoprotein levels in epithelial cell lines by mass spectrometry, J. Virol., 86, 9465, 10.1128/JVI.01032-12 · DOI · Paper page
- Schwarz, 1985, Structure and transcription of human papillomavirus sequences in cervical carcinoma cells, Nature, 314, 111, 10.1038/314111a0 · DOI
- Seol, 2000, Transcriptional activation of the hepatocyte growth factor receptor (c-met) gene by its ligand (hepatocyte growth factor) is mediated through AP-1, Oncogene, 19, 1132, 10.1038/sj.onc.1203404 · DOI
- Shimabukuro, 2001, Hepatocyte growth factor/scatter factor is implicated in the mode of stromal invasion of uterine squamous cervical cancer, Gynecol. Oncol., 83, 205, 10.1006/gyno.2001.6347 · DOI
- Spurgeon, 2017, Human papillomavirus and the stroma: bidirectional crosstalk during the virus life cycle and carcinogenesis, Viruses, 9, 10.3390/v9080219 · DOI
- Steele, 2002, Variable expression of some "housekeeping" genes during human keratinocyte differentiation, Anal. Biochem., 307, 341, 10.1016/S0003-2697(02)00045-3 · DOI
- Steffan, 2011, The HGF-met signaling axis: emerging themes and targets of inhibition, Curr. Protein Pept. Sci., 12, 12, 10.2174/138920311795659425 · DOI
- Thiery, 2006, Complex networks orchestrate epithelial-mesenchymal transitions, Nat. Rev. Mol. Cell Biol., 7, 131, 10.1038/nrm1835 · DOI
- Trusolino, 2010, MET signalling: principles and functions in development, organ regeneration and cancer, Nat. Rev. Mol. Cell Biol., 11, 834, 10.1038/nrm3012 · DOI
- Tummers, 2015, The interferon-related developmental regulator 1 is used by human papillomavirus to suppress NFkappaB activation, Nat. Commun., 6, 6537, 10.1038/ncomms7537 · DOI
- Velpula, 2012, EGFR and c-met cross talk in glioblastoma and its regulation by human cord blood stem cells, Transl. Oncol., 5, 379, 10.1593/tlo.12235 · DOI · Paper page
- Venuti, 2011, Papillomavirus E5: the smallest oncoprotein with many functions, Mol. Cancer, 10, 140, 10.1186/1476-4598-10-140 · DOI
- Walker, 2003, Hepatocyte growth factor and c-Met in cervical intraepithelial neoplasia: overexpression of proteins associated with oncogenic human papillomavirus and human immunodeficiency virus, Clin. Cancer Res., 9, 273
- Wilson, 2005, Differentiation of HPV-containing cells using organotypic "raft" culture or methylcellulose, Methods Mol. Med., 119, 157
- Woodby, 2016, The interaction Between human papillomaviruses and the stromal microenvironment, Prog. Mol. Biol. Transl. Sci., 144, 169, 10.1016/bs.pmbts.2016.09.003 · DOI
- Woodman, 2007, The natural history of cervical HPV infection: unresolved issues, Nat. Rev. Cancer, 7, 11, 10.1038/nrc2050 · DOI
- Zhang, Y., Wu, J.Z., Yang, Y.Q., Ma, R., Zhang, J.Y., Feng, J.F., 2014. Expression of growthregulated oncogene1, hepatocyte growth factor, plateletderived growth factorAA and soluble Eselectin and their association with highrisk human papillomavirus infection in squamous cell carcinoma of the uterine cervix. Molecular Medicine Reports. · DOI
- zur Hausen, 1996, Papillomavirus infections--a major cause of human cancers, Biochim. Biophys. Acta, 1288, F55
- zur Hausen, 2009, Papillomaviruses in the causation of human cancers - a brief historical account, Virology, 384, 260, 10.1016/j.virol.2008.11.046 · DOI · Paper page
Cited by
Basukala, O., & Banks, L. (2021) · Viruses · doi:10.3390/v13101892 · Cited by 137
Metadata
- Authors
- Scott, M. L., Coleman, D. T., Kelly, K. C., Carroll, J. L., Woodby, B., Songock, W. K., Cardelli, J. A., & Bodily, J. M.
- Venue
- Virology
- Publisher
- Elsevier BV
- Published
- 2018-06
- Volume
- 519
- Pages
- 1-11
- ISSN
- 0042-6822
- PMC
- PMC5971161
- Cited by
- 35
- References
- 2
- Language
- en
- Licence
- Funders
- National Institute of General Medical Sciences (P30-GM110703)
- National Institute of Allergy and Infectious Diseases (R01AI118904)
- LSUHSC Research Council
- Feist-Weiller Cancer Center
- Biomedical Research Foundation
- National Institutes of Health (8 P20 GM103433, R01AI118904)
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