Cited by 374

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300

Patel, Daksha, Huang, Shih‐Min, Baglia, Laurel A., McCance, Dennis J.·1999·The EMBO Journal

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/emboj/18.18.5061

Cites

6 of 6 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 6 references

Research works printed but not linked: 55

  1. Ait‐Si‐Ali S et al. (1998) Histone deacetylase activity of CBP is controlled by cycle‐dependent kinases and oncoprotein E1A. Nature, 396, 184‐186. · DOI
  2. Angel P and Karin M (1991) The role of Jun, Fos and the AP‐1 complex in cell‐proliferation and transformation. Biochim Biophys Acta, 1072, 129‐157.
  3. Arias J, Alberts AS, Brindle P, Claret FX, Smeal T, Karin M, Feramisco J and Montminy M (1994) Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature, 370, 226‐229. · DOI
  4. Avantaggiati ML, Ogryzko V, Gardner K, Giordano A, Levine AS and Kelly K (1997) Recruitment of p300/CBP in p53‐dependent signal pathways. Cell, 89, 1175‐1184. · DOI
  5. Baldwin AS (1996) The NF‐κB and Iκ‐B proteins: New discoveries and insights. Annu Rev Immunol, 14, 649‐681. · DOI · Paper page
  6. Bannister AJ and Kouzarides T (1995) CBP‐induced stimulation of c‐Fos activity is abrogated by E1A. EMBO J, 14, 4758‐4762. · DOI
  7. Bannister AJ and Kouzarides T (1996) The CBP co‐activator is a histone acetyltransferase. Nature, 384, 641‐643. · DOI
  8. Bontkes HJ, Walboomers JM, Meijer CJ, Helmerhorst TJ and Stern PL (1998) Specific HLA class I down‐regulation is an early event in cervical dysplasia associated with clinical progression. Lancet, 351, 187‐188. · DOI
  9. Chakravarti D, Ogryzko V, Kao H‐Y, Nash A, Chen H, Nakatani Y and Evans RM (1999) A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell, 96, 393‐403. · DOI · Paper page
  10. Cromme FV, Airey J, Heemels MT, Ploegh HL, Keating PJ, Stern PL, Meijer CJ and Walboomers JM (1994a) Loss of transporter protein, encoded by the TAP‐1 gene, is highly correlated with loss of HLA expression in cervical carcinomas. J Exp Med, 179, 335‐340. · DOI
  11. Cromme FV, van Bommel PF, Walboomers JM, Gallee MP, Stern PL, Kenemans P, Helmerhorst TJ, Stukart MJ and Meijer CJ (1994b) Differences in MHC and TAP‐1 expression in cervical cancer lymph node metastases as compared with the primary tumours. Br J Cancer, 69, 1176‐1181. · DOI
  12. Crook T, Tidy JA and Vousden KH (1991) Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans‐activation. Cell, 67, 547‐556. · DOI
  13. Dai P, Akimaru H, Tanaka Y, Hou DX, Yasukawa T, Kanei‐Ishii C, Takahashi T and Ishii S (1996) CBP as a transcriptional coactivator of c‐Myb. Genes Dev, 10, 528‐540. · DOI
  14. Dalal S, Gao Q, Androphy EJ and Band V (1996) Mutational analysis of human papillomavirus type 16 E6 demonstrates that p53 degradation is necessary for immortalization of mammary epithelial cells. J Virol, 70, 683‐688. · DOI · Paper page
  15. Eckner R, Ewen ME, Newsome D, Gerdes M, DeCaprio JA, Lawrence JB and Livingston DM (1994) Molecular cloning and functional analysis of the adenovirus E1A‐associated 300‐kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev, 8, 869‐884. · DOI
  16. Eckner R, Ludlow JW, Lill NL, Oldread E, Arany Z, Modjtahedi N, DeCaprio JA, Livingston DM and Morgan JA (1996a) Association of p300 and CBP with simian virus 40 large T antigen. Mol Cell Biol, 16, 3454‐3464. · DOI
  17. Eckner R, Yao TP, Oldread E and Livingston DM (1996b) Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B‐cell differentiation. Genes Dev, 10, 2478‐2490. · DOI
  18. Foster SA, Demers GW, Etscheid BG and Galloway DA (1994) The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D‐induced growth arrest. J Virol, 68, 5698‐5705. · DOI · Paper page
  19. Funk JO, Waga S, Harry JB, Espling E, Stillman B and Galloway DA (1997) Inhibition of CDK activity and PCNA‐dependent DNA replication by p21 is blocked by interaction with the HPV‐16 E7 oncoprotein. Genes Dev, 11, 2090‐2100. · DOI · Paper page
  20. Giles RH, Peters DJ and Breuning MH (1998) Conjunction dysfunction: CBP/p300 in human disease. Trends Genet, 14, 178‐183. · DOI
  21. Gu W, Shi X‐L and Roeder RG (1997) Synergistic activation of transcription by CBP and p53. Nature, 387, 819‐822. · DOI
  22. Hamamori Y, Sartorelli V, Ogryzko V, Puri PL, Wu H‐Y, Wang JYJ, Nakatani Y and Kedes L (1999) Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein Twist and adenoviral oncoprotein E1A. Cell, 96, 405‐413. · DOI · Paper page
  23. Hu Y, Baud V, Delhase M, Zhang P, Deerinck T, Ellisman M, Johnson R and Karin M (1999) Abnormal morphogenesis but intact IKK activation in mice lacking the IKK‐α subunit of IκB. Science, 284, 316‐320. · DOI
  24. Jones DL, Alani RM and Munger K (1997) The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1‐mediated inhibition of cdk2. Genes Dev, 11, 2101‐2111. · DOI · Paper page
  25. Kamei Y et al. (1996) A CBP integrator complex mediates transcriptional activation and AP‐1 inhibition by nuclear receptors. Cell, 85, 403‐414. · DOI · Paper page
  26. Kawasaki H, Eckner R, Yao TP, Taira K, Chiu R, Livingston DM and Yokoyama KK (1998) Distinct roles of the co‐activators p300 and CBP in retinoic‐acid‐induced F9‐cell differentiation. Nature, 393, 284‐289. · DOI
  27. Keating PJ, Cromme FV, Duggan‐Keen M, Snijders PJ, Walboomers JM, Hunter RD, Dyer PA and Stern PL (1995) Frequency of down‐regulation of individual HLA‐A and ‐B alleles in cervical carcinomas in relation to TAP‐1 expression. Br J Cancer, 72, 405‐411. · DOI
  28. Korzus E, Torchia J, Rose DW, Xu L, Kurokawa R, McInerney EM, Mullen TM, Glass CK and Rosenfeld MG (1998) Transcription factor‐specific requirements for coactivators and their acetyltransferase functions. Science, 279, 703‐707. · DOI
  29. Kurokawa R, Kalafus D, Ogliastro MH, Kioussi C, Xu L, Torchia J, Rosenfeld MG and Glass CK (1998) Differential use of CREB binding protein‐coactivator complexes. Science, 279, 700‐703. · DOI
  30. Kwok RP, Laurance ME, Lundblad JR, Goldman PS, Shih H, Connor LM, Marriott SJ and Goodman RH (1996) Control of cAMP‐regulated enhancers by the viral transactivator Tax through CREB and the co‐activator CBP. Nature, 380, 642‐646. · DOI
  31. Lee JS, See RH, Deng T and Shi Y (1996) Adenovirus E1A downregulates cJun‐ and JunB‐mediated transcription by targeting their coactivator p300. Mol Cell Biol, 16, 4312‐4326. · DOI
  32. Lundblad JR, Kwok RP, Laurance ME, Harter ML and Goodman RH (1995) Adenoviral E1A‐associated protein p300 as a functional homologue of the transcriptional co‐activator CBP. Nature, 374, 85‐88. · DOI
  33. McCance DJ (1998) Human papillomaviruses and cervical cancer. J Med Microbiol, 47, 371‐373. · DOI
  34. Nakajima T, Uchida C, Anderson SF, Lee CG, Hurwitz J, Parvin JD and Montminy M (1997a) RNA helicase A mediates association of CBP with RNA polymerase II. Cell, 90, 1107‐1112. · DOI
  35. Nakajima T, Uchida C, Anderson SF, Parvin JD and Montminy M (1997b) Analysis of a cAMP‐responsive activator reveals a two‐component mechanism for transcriptional induction via signal‐dependent factors. Genes Dev, 11, 738‐747. · DOI
  36. Oelgeschlager M, Janknecht R, Krieg J, Schreek S and Luscher B (1996) Interaction of the co‐activator CBP with Myb proteins: effects on Myb‐specific transactivation and on the cooperativity with NF‐M. EMBO J, 15, 2771‐2780. · DOI
  37. Ogryzko VV, Schiltz RL, Russanova V, Howard BH and Nakatani Y (1996) The transcriptional coactivators p300 and CBP are histone deacetylases. Cell, 87, 953‐959. · DOI · Paper page
  38. Onate SA, Tsai SY, Tsai MJ and O'Malley BW (1995) Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science, 270, 1354‐1357. · DOI
  39. Puri PL, Avantaggiati ML, Balsano C, Sang N, Graessmann A, Giordano A and Levrero M (1997) p300 is required for MyoD‐dependent cell cycle arrest and muscle‐specific gene transcription. EMBO J, 16, 369‐383. · DOI
  40. Scheffner M, Werness BA, Huibregtse JM, Levine AJ and Howley PM (1990) The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell, 63, 1129‐1136. · DOI · Paper page
  41. Scheffner M, Huibregtse JM, Vierstra RD and Howley PM (1993) The HPV‐16 E6 and E6‐AP complex functions as a ubiquitin‐protein ligase in the ubiquitination of p53. Cell, 75, 495‐505. · DOI · Paper page
  42. Scheffner M, Huibregtse JM and Howley PM (1994) Identification of a human ubiquitin‐conjugating enzyme that mediates the E6‐AP‐dependent ubiquitination of p53. Proc Natl Acad Sci USA, 91, 8797‐8801. · DOI
  43. Sherman L and Schlegel R (1996) Serum‐ and calcium‐induced differentiation of human keratinocytes is inhibited by the E6 oncoprotein of human papillomavirus type 16. J Virol, 70, 3269‐3279. · DOI
  44. Sherman L, Jackman A, Itzhaki H, Stoppler MC, Koval D and Schlegel R (1997) Inhibition of serum‐ and calcium‐induced differentiation of human keratinocytes by HPV16 E6 oncoprotein: role of p53 inactivation. Virology, 237, 296‐306. · DOI
  45. Shikama N, Lyon J and La Thangue NB (1997) The p300/CBP family: integrating signals with transcription factors and chromatin. Trends Cell Biol, 7, 230‐236. · DOI
  46. Takeda K et al. (1999) Limb and skin abnormalities in mice lacking IIKα. Science, 284, 313‐316. · DOI
  47. Tay SK, Jenkins D, Maddox P, Campion M and Singer A (1987a) Subpopulations of Langerhans' cells in cervical neoplasia. Br J Obstet Gynaecol, 94, 10‐15. · DOI
  48. Tay SK, Jenkins D, Maddox P, Hogg N and Singer A (1987b) Tissue macrophage response in human papillomavirus infection and cervical intraepithelial neoplasia. Br J Obstet Gynaecol, 94, 1094‐1097. · DOI
  49. Tay SK, Jenkins D, Maddox P and Singer A (1987c) Lymphocyte phenotypes in cervical intraepithelial neoplasia and human papillomavirus infection. Br J Obstet Gynaecol, 94, 16‐21. · DOI
  50. Tay SK, Jenkins D and Singer A (1987d) Natural killer cells in cervical intraepithelial neoplasia and human papillomavirus infection. Br J Obstet Gynaecol, 94, 901‐906. · DOI
  51. Tomic‐Canic M, Komine M, Freedberg IM and Blumenberg M (1998) Epidermal signal transduction and transcription factor activation in activated keratinocytes. J Dermatol Sci, 17, 167‐181. · DOI
  52. Torchia J, Rose DW, Inostroza J, Kamei Y, Westin S, Glass CK and Rosenfeld MG (1997) The transcriptional co‐activator p/CIP binds CBP and mediates nuclear‐receptor function. Nature, 387, 677‐684. · DOI
  53. Yang XJ, Ogryzko VV, Nishikawa J, Howard BH and Nakatani Y (1996) A p300/CBP‐associated factor that competes with the adenoviral oncoprotein E1A. Nature, 382, 319‐324. · DOI
  54. Yuan W, Condorelli G, Caruso M, Felsani A and Giordano A (1996) Human p300 protein is a coactivator for the transcription factor MyoD. J Biol Chem, 271, 9009‐9013. · DOI
  55. Zimmermann H, Degenkolbe R, Bernard H‐U and O'Connor MJ (1999) The human papillomavirus type 16 E6 oncoprotein can down‐regulate p53 by targeting the transcriptional coactivator CBP/p300. J Virol, 73, 6209‐6219. · DOI · Paper page

Cited by

See all 374

Metadata

Authors
Patel, D., Huang, S., Baglia, L. A., & McCance, D. J.
Venue
The EMBO Journal
Published
1999-09-15
Volume
18
Issue
18
Pages
5061-5072
ISSN
  • 0261-4189
  • 1460-2075
Cited by
374
References
6
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300. https://app.cochat.ai/papers/10.1093/emboj/18.18.5061
The paper
Patel, D., Huang, S., Baglia, L. A., & McCance, D. J. (1999). The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300. The EMBO Journal. https://doi.org/10.1093/emboj/18.18.5061