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Placental expression of the insulin receptor binding protein GRB10: Relation to human fetoplacental growth and fetal gender

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Partial Loss of Genomic Imprinting Reveals Important Roles for Kcnq1 and Peg10 Imprinted Domains in Placental Development

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The origins of genomic imprinting in mammals

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Parental bias in expression and interaction of genes in the equine placenta

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Effects of superovulation, in vitro fertilization, and oocyte in vitro maturation on imprinted gene Grb10 in mouse blastocysts

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miR-126 regulates glycogen trophoblast proliferation and DNA methylation in the murine placenta

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Klf14 is an imprinted transcription factor that regulates placental growth

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Potential roles of imprinted genes in the teratogenic effects of alcohol on the placenta, somatic growth, and the developing brain

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Imprinted genes and the manipulation of parenting in mammals

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Detecting Maternal-Effect Loci by Statistical Cross-Fostering

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Dynamic Expression of Imprinted Genes in the Developing and Postnatal Pituitary Gland

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Perturbations to the IGF 1 growth pathway and adult energy homeostasis following disruption of mouse chromosome 12 imprinting

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Maternal GRB10 microdeletion is a novel cause of cystic placenta: Spectrum of genomic changes in the etiology of enlarged cystic placenta

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United by conflict: Convergent signatures of parental conflict in angiosperms and placental mammals

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GRB10 Imprinting Is Eutherian Mammal Specific

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Behavioural effects of imprinted genes

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Genomic imprinting and mammalian reproduction

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Aberrant hypomethylation at imprinted differentially methylated regions is involved in biparental placental mesenchymal dysplasia

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Co-Expression Network and Integrative Analysis of Metabolome and Transcriptome Uncovers Biological Pathways for Fertility in Beef Heifers

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Genomic Imprinting of Grb10 : Coadaptation or Conflict?

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Identification and Epigenetic Analysis of a Maternally Imprinted Gene Qpct

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Developmental Biology of the Placenta

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Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes

Moorwood, K., Smith, F. M., Garfield, A. S., & Ward, A. (2024) · BMC Biology · doi:10.1186/s12915-024-01926-w · Cited by 8 · see citing works

Influencing the Social Group

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Circulating Placental Alkaline Phosphatase Expressing Exosomes in Maternal Blood Showed Temporal Regulation of Placental Genes

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Association of the intronic polymorphism rs12540874 A>G of the GRB10 gene with high birth weight

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Effect of candidate genes for maternal ability on piglet survival and growth

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Enrichment of trimethyl histone 3 lysine 4 in the Dlk1 and Grb10 genes affects pregnancy outcomes due to dietary manipulation of excess folic acid and low vitamin B12

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Epigenetic regulation of gene expression: an overview of classical and recently discovered novel players

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Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism

Moorwood, K., Smith, F. M., Garfield, A. S., Cowley, M., Holt, L. J., Daly, R. J., & Ward, A. (2024) · BMC Biology · doi:10.1186/s12915-024-02018-5 · Cited by 4 · see citing works

Single-cell transcriptome analysis reveals abnormal angiogenesis and placentation by loss of imprinted glutaminyl-peptide cyclotransferase

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Sex and fetal genome influence gene expression in pig endometrium at the end of gestation

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Generation of live mice from haploid ESCs with germline-DMR deletions or switch

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Assisted reproduction causes intrauterus growth restriction by disrupting placental lipid metabolismPreprint

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Transient grb10a Knockdown Permanently Alters Growth, Cardiometabolic Phenotype and the Transcriptome in Danio rerioPreprint

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The Role of Genomic Imprints in Placental Biology

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Imprinted genes and placental growth

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Imprinted genes, impulsivity and risk-taking

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Genomic imprinting

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Male-Specific Transcription Factor Occupancy Alone Does Not Account for Differential Methylation at Imprinted Genes in themouseGerm Cell Lineage

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Use of genetic markers in pig breeding programs

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Impulsive choice in mice lacking paternal expression of Grb10 suggests intra-genomic conflict in behaviorPreprint

Dent, C. L., Humby, T., Lewis, K. S., Ward, A., Fischer-Colbrie, R., Wilkinson, L. S., Wilkins, J. F., & Isles, A. R. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/281873

Imprinted Gene Regulation in the Placenta and Fetal Development

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Genomic imprinting and developmental physiology: intrauterine growth and postnatal period

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Grb7 , Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolismPreprint

Moorwood, K., Smith, F. M., Garfield, A. S., Cowley, M., Holt, L. J., Daly, R. J., & Ward, A. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.31.578179

Cryopreservation Effect on Genetic/Epigenetic Function: Neonatal Outcomes

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Developmental Biology of the Placenta

Hui, P. (2025) · Springer eBooks · doi:10.1007/978-3-031-83545-2_2

Transcriptome remodelling and changes in growth and cardiometabolic phenotype result following Grb10a knockdown in the early life of the zebrafish

Evans, B. L., Garner, T., Leonibus, C. D., Wright, L., Sharps, M. C., Wearing, O. H., Ripley, D. M., Shiels, H. A., Hurlstone, A. F. L., Clayton, P., et al. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05784-9

Additional file 2 of Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism

Moorwood, K., Smith, F. M., Garfield, A. S., Cowley, M., Holt, L. J., Daly, R. J., & Ward, A. (2024) · Figshare · doi:10.6084/m9.figshare.27132735

Additional file 5 of Sex and fetal genome influence gene expression in pig endometrium at the end of gestation

Bonnet, A., Bluy, L. E., Gress, L., Canario, L., Ravon, L., Sécula, A., Billon, Y., & Liaubet, L. (2024) · Figshare · doi:10.6084/m9.figshare.26696469

Additional file 2 of Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes

Moorwood, K., Smith, F. M., Garfield, A. S., & Ward, A. (2024) · Figshare · doi:10.6084/m9.figshare.26727838

Additional file 3 of Aberrant hypomethylation at imprinted differentially methylated regions is involved in biparental placental mesenchymal dysplasia

Aoki, S., Higashimoto, K., Hidaka, H., Ohtsuka, Y., Aoki, S., Mishima, H., Yoshiura, K., Nakabayashi, K., Hata, K., Yatsuki, H., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19785823

Additional file 1 of Sex and fetal genome influence gene expression in pig endometrium at the end of gestation

Bonnet, A., Bluy, L. E., Gress, L., Canario, L., Ravon, L., Sécula, A., Billon, Y., & Liaubet, L. (2024) · Figshare · doi:10.6084/m9.figshare.25459583

Additional file 1 of Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism

Moorwood, K., Smith, F. M., Garfield, A. S., Cowley, M., Holt, L. J., Daly, R. J., & Ward, A. (2024) · Figshare · doi:10.6084/m9.figshare.27132732

Placental expression of the insulin receptor binding protein GRB10: Relation to human fetoplacental growth and fetal gender

Mukhopadhyay, A., Ravikumar, G., Dwarkanath, P., Meraaj, H., Thomas, A., Crasta, J., Thomas, T. S., Kurpad, A. V., & Sridhar, T. S. (2015) · Placenta · doi:10.1016/j.placenta.2015.09.006 · Cited by 25 · see citing works

Investigating the role of the imprinted Grb10 gene in the regulation of maternal nutrient transfer.

Cowley, M. (2009) · The University of Bath Online Publications Store (The University of Bath)

Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism

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Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression

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Disruption of the imprinted GrblO gene leads to disproportionate overgrowth by an Igf2-independent mechanism

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