Long-term outcomes from the PEARLS randomized trial for the treatment of depression in patients with epilepsy
Abstract
Depression is associated with higher rates of suicide and lower quality of life in individuals with epilepsy. We previously published the 12-month outcome from our randomized clinical trial of PEARLS (Ciechanowski P, Chaytor N, Miller J, et al. Epilepsy Behav. Epub 5 July 2010). The purpose of this study was to determine the long-term effectiveness of PEARLS, a home-based collaborative care intervention consisting of problem-solving treatment, behavioral activation, and psychiatric consultation, in individuals with epilepsy. Patients were randomly assigned to PEARLS (N=40) or usual care (N=40), and assessed at baseline and 6, 12, and 18 months. Patients assigned to PEARLS achieved lower depression severity (P<0.05) (Hopkins Symptoms Checklist-20), lower suicidal ideation (P<0.02), and better emotional well being (QOLIE-31) (P<0.02) over 18 months, compared with patients given the usual care. The PEARLS program significantly reduces depressive symptoms in adults with epilepsy, and this effect is maintained for 18 months after baseline and for more than 1 year after completion of home visits.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Severity of depressive symptoms was used as an inclusion criterion in 5 studies (21%).
“Severity of depressive symptoms was used as an inclusion criterion in 5 studies (21%; see Table 1). 26,27,29 -32”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [26]
The remaining 7 studies (29%) employed a usual care (UC)/treatment as usual (TAU) control group.
“The remaining 7 studies (29%) employed a usual care (UC)/treatment as usual (TAU) control group. 26,27,31,41,44,48 -50”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [26]
Six interventions (25%) were delivered through individual sessions.
“6 interventions (25%) were delivered through individual sessions, 9,15,26,27,43,44,48”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [26]
QOLIE-31/31-P/-89 was used in 17 studies (71%), of which 12 (70%) were considered for meta-analyses due to satisfactory methodological homogeneity.
“It was used in 17 studies (71%), of which 12 (70%) were considered for meta-analyses due to satisfactory methodological homogeneity. 26,27,29,30,33,36,37,41,46,47,49,50”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [26]
The meta-analysis comprised data from 9 studies (37%) with a total of 468 participants.
“Consequently, the meta-analysis comprised data from 9 studies (37%) 26 -30,33,36,46,49,50 with a total of 468 participants (see studies highlighted in gray in Table 1).”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [26]
Four studies (17%) were rated as high ROB due to evidence of selective outcome reporting within the publications.
“Four studies (17%) 26,27,29,31,41 were rated as high ROB due to evidence of selective outcome reporting within the publications.”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [26]
Three studies (12%) provided details regarding the attempt to ensure fidelity to the intervention protocol by employing standard training protocols and supervision.
“Three studies (12%), however, provided details regarding the attempt to ensure fidelity to the intervention protocol by employing standard training protocols and supervision. 26 -28,31”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [26]
The risk of infidelity to the intervention protocol was considered to be relatively low whenever the therapist delivering the intervention coincided with the developer of the intervention protocol (n = 6, 25%).
“Furthermore, the risk of infidelity to the intervention protocol was considered to be relatively low whenever the therapist delivering the intervention coincided with the developer of the intervention protocol (n = 6, 25%) 25 -27,34,46,48,49”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [26]
Seven studies (64%) reported a significant postintervention difference between the intervention and the control groups for depressive symptoms.
“Seven studies (64%) reported a significant postintervention difference between the intervention and the control groups. 26 -29,31,32,36,46”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [26]
Five studies (55%) found no significant differences between the treatment and control groups in seizure frequency.
“whereas the other 5 studies (55%) found no significant differences between the groups. 26,27,33,35,38,42”
From Cochrane systematic review and meta-analysis of the impact of psychological treatments for people with epilepsy on health-related quality of life (2018) · cites this paper as [26]
The GAD-7 has been validated by significant positive correlations with a number of anxiety measures, including the Hamilton Anxiety Scale, Beck Anxiety Inventory and the anxiety sub-scale of Symptom Checklist-90, and has previously been used as a screening tool in epilepsy.
“The GAD-7 has been validated by significant positive correlations with a number of anxiety measures, including the Hamilton Anxiety Scale, Beck Anxiety Inventory and the anxiety sub-scale of Symptom Checklist-90 [17, 21] and it has previously been used as a screening tool in epilepsy [22].”
From A prospective service evaluation of acceptance and commitment therapy for patients with refractory epilepsy (2015) · cites this paper as [17]
Cites
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910 · see citing works
Spitzer, R. L. (1999) · JAMA · doi:10.1001/jama.282.18.1737 · Cited by 9,802 · see citing works
Detecting Alcoholism: The CAGE Questionnaire
Ewing, J. A. (1984) · JAMA · doi:10.1001/jama.1984.03350140051025 · Cited by 3,005 · see citing works
Unützer, J., Katon, W., Callahan, C. M., Williams, Jr., Hunkeler, E., Harpole, L., Hoffing, M., Della Penna, R. D., Noël, P. H., Lin, E. H. B., et al. (2002) · JAMA · doi:10.1001/jama.288.22.2836 · Cited by 2,405 · see citing works
Six-item screener to identify cognitive impairment among potential subjects for clinical research
Callahan, C. M., Unverzagt, F. W., Hui, S. L., Perkins, A. J., & Hendrie, H. C. (2002) · Medical Care · doi:10.1097/00005650-200209000-00007 · Cited by 1,499 · cited 1× · see citing works
“cognitive impairment (5-minute recall of three items and orientation from the Folstein Mini-Mental Status Exam [17]), pregnancy or nursing, bipolar or psychotic disorder, current psychiatric treatment, or substance abuse based on the CAGE questionnaire [18].”
MethodDevelopment and cross-cultural translations of a 31-item quality of life in epilepsy inventory
Cramer, J. A., Perrine, K., Devinsky, O., Bryant‐Comstock, L., Meador, K., & Hermann, B. (1998) · Epilepsia · doi:10.1111/j.1528-1157.1998.tb01278.x · Cited by 782 · see citing works
Depression in epilepsy: prevalence, clinical semiology, pathogenic mechanisms, and treatment
Kanner, A. M. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00469-4 · Cited by 525 · see citing works
Psychiatric comorbidity in epilepsy.
Swinkels, W. A. M., Kuyk, J., van Dyck, R., & Spinhoven, P. (2005) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2005.04.012 · Cited by 499 · see citing works
Rates and risk factors for suicide, suicidal ideation, and suicide attempts in chronic epilepsy
Jones, J. E., Hermann, B. P., Barry, J. J., Gilliam, F. G., Kanner, A. M., & Meador, K. J. (2003) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2003.08.019 · Cited by 452 · see citing works
Self-citationCommunity-Integrated Home-Based Depression Treatment in Older Adults: A Randomized Controlled Trial
Ciechanowski, P., Wagner, E., Schmaling, K., Schwartz, S., Williams, B., Diehr, P., Kulzer, J., Gray, S., Collier, C., & LoGerfo, J. (2004) · JAMA · doi:10.1001/jama.291.13.1569 · Cited by 406 · see citing works
Self-citationA Comparison of Two Psychiatric Screening Tests
Goldberg, D. P., Rickels, K., Downing, R. W., & Hesbacher, P. T. (1976) · The British Journal of Psychiatry · doi:10.1192/bjp.129.1.61 · Cited by 400 · see citing works
Kanner, A. M., Barry, J. J., Gilliam, F., Hermann, B., & Meador, K. J. (2010) · Epilepsia · doi:10.1111/j.1528-1167.2010.02582.x · Cited by 182 · see citing works
Self-citationPsychiatric Screening in a Medical Clinic
Glass, R. M. (1978) · Archives of General Psychiatry · doi:10.1001/archpsyc.1978.01770340039003 · Cited by 136 · see citing works
PEARLS depression treatment for individuals with epilepsy: A randomized controlled trial
Ciechanowski, P., Chaytor, N., Miller, J., Fraser, R., Russo, J., Unutzer, J., & Gilliam, F. (2010) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2010.06.003 · Cited by 130 · see citing works
Self-citationIncident major depression does not affect neuropsychological functioning in HIV-infected men
Cysique, L. A., Deutsch, R., Atkinson, J. H., Young, C., Marcotte, T. D., Dawson, L., Grant, I., Heaton, R. K., & THE HNRC GROUP (2006) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617707070026 · Cited by 128 · see citing works
Risk factors for depression in patients with epilepsy
Grabowska–Grzyb, A., Jędrzejczak, J., Nagańska, E., & Fiszer, U. (2006) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2005.12.005 · Cited by 125 · see citing works
Treatment of depressive disorders in epilepsy patients
Gilliam, F. G., & Kanner, A. M. (2002) · Epilepsy & Behavior · doi:10.1016/s1525-5069(02)00503-0 · Cited by 122 · see citing works
Self-citationDepression in epilepsy: a frequently neglected multifaceted disorder
Kanner, A. M. (2003) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2003.10.004 · Cited by 106 · see citing works
Park, S.-P., Song, H. S., Hwang, Y., Lee, H.-W., Suh, C.-K., & Kwon, S. (2010) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2010.05.021 · Cited by 69 · see citing works
Chaytor, N. S., Temkin, N. R., Machamer, J., & DIKMEN, S. S. (2007) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617707070592 · Cited by 65 · see citing works
Self-citationCorrelates of Functional Status 3–5 Years after Traumatic Brain Injury with CT Abnormalities
Temkin, N., Machamer, J., & Dikmen, S. (2003) · Journal of Neurotrauma · doi:10.1089/089771503321532815 · Cited by 65 · see citing works
Epilepsy and common comorbidities: improving the outpatient epilepsy encounter
Gilliam, F. G., Mendiratta, A., Pack, A. M., & Bazil, C. W. (2005) · Epileptic Disorders · doi:10.1684/j.1950-6945.2005.tb00149.x · Cited by 59 · see citing works
Self-citationLiving Well II: A review of progress since 2003
AUSTIN, J. K., Carr, D. A., & Hermann, B. P. (2006) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2006.08.015 · Cited by 39 · see citing works
Treatment of depression in patients with epilepsy: problems, pitfalls, and some solutions
Krishnamoorthy, E. S. (2003) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2003.08.017 · Cited by 28 · see citing works
What is effective treatment of depression in people with epilepsy?
Barry, J. J., & Jones, J. E. (2005) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2005.03.017 · Cited by 19 · see citing works
Driving and flying with epilepsy
Drazkowski, J. F. (2007) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-007-0050-2 · Cited by 11 · see citing works
Flagged first, then by citations
1 of the 27 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Collaborative care for depression and anxiety problems
Archer, J., Bower, P., Gilbody, S., Lovell, K., Richards, D., Gask, L., Dickens, C., & Coventry, P. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006525.pub2 · Cited by 1,126 · see citing works
Michaelis, R., Tang, V., Goldstein, L. H., Reuber, M., LaFrance, W. C., Lundgren, T., Modi, A. C., & Wagner, J. L. (2018) · Epilepsia · doi:10.1111/epi.14444 · Cited by 167 · see citing works
Michaelis, R., Tang, V., Wagner, J. L., Modi, A. C., LaFrance, W. C., Goldstein, L. H., Lundgren, T., & Reuber, M. (2018) · Epilepsia · doi:10.1111/epi.13989 · Cited by 122 · see citing works
Psychological treatments for people with epilepsy
Michaelis, R., Tang, V. Y. H., Wagner, J. L., Modi, A. C., LaFrance, W. C., Jr., Goldstein, L. H., Lundgren, T., & Reuber, M. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012081.pub2 · Cited by 101 · see citing works
Diagnosing and treating depression in epilepsy
Elger, C. E., Johnston, S. A., & Hoppe, C. (2016) · Seizure · doi:10.1016/j.seizure.2016.10.018 · Cited by 88 · see citing works
Mula, M., Brodie, M. J., de Toffol, B., Guekht, A. B., Hečimović, H., Kanemoto, K., Kanner, A. M., Teixeira, A. L., & Wilson, S. J. (2021) · Epilepsia · doi:10.1111/epi.17140 · Cited by 86 · see citing works
The Managing Epilepsy Well Network:
Sajatovic, M., Jobst, B. C., Shegog, R., Bamps, Y. A., Begley, C. E., Fraser, R., Johnson, E. K., Pandey, D. K., Quarells, R. C., Scal, P. B., et al. (2017) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2016.07.026 · Cited by 82 · see citing works
Self-citationPsychobehavioral therapy for epilepsy
Tang, V., Michaelis, R., & Kwan, P. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2013.12.004 · Cited by 76 · see citing works
Tian, N., Cui, W., Zack, M. M., Kobau, R., Fowler, K. A., & Hesdorffer, D. C. (2016) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2016.05.028 · Cited by 73 · see citing works
Collaboration between local health and local government agencies for health improvement
Hayes, S. L., Mann, M. K., Morgan, F. M., Kelly, M. J., & Weightman, A. L. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007825.pub6 · Cited by 69 · see citing works
Depressive syndromes in neurological disorders
Hellmann‐Regen, J., Piber, D., Hinkelmann, K., Gold, S. M., Heesen, C., Spitzer, C., Endres, M., & Otte, C. (2013) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-013-0448-6 · Cited by 64 · see citing works
Cognitive behavior therapy for depression in people with epilepsy: A systematic review
Gandy, M., Sharpe, L., & Perry, K. N. (2013) · Epilepsia · doi:10.1111/epi.12345 · Cited by 65 · see citing works
Quality of life is social – Towards an improvement of social abilities in patients with epilepsy
Szemere, E., & Jokeit, H. (2014) · Seizure · doi:10.1016/j.seizure.2014.12.008 · Cited by 64 · see citing works
Self-management in epilepsy: Why and how you should incorporate self-management in your practice
Helmers, S. L., Kobau, R., Sajatovic, M., Jobst, B. C., Privitera, M., Devinsky, O., Labiner, D. M., Escoffery, C., Begley, C. E., Shegog, R., et al. (2017) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2016.11.015 · Cited by 64 · see citing works
Self-citationUnderutilization of epilepsy surgery: Part II: Strategies to overcome barriers
Samanta, D., Singh, R. K. R., Gedela, S., Perry, M. S., & Arya, R. (2021) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2021.107853 · Cited by 59 · see citing works
Dewhurst, E., Novakova, B., & Reuber, M. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.01.010 · Cited by 55 · see citing works
Treatments for patients with comorbid epilepsy and depression: A systematic literature review
Mehndiratta, P., & Sajatovic, M. (2013) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2013.03.029 · Cited by 50 · see citing works
Cognitive Behaviour Therapy to Improve Mood in People with Epilepsy: A Randomised Controlled Trial
Gandy, M., Sharpe, L., Nicholson Perry, K., Thayer, Z., Miller, L., Boserio, J., & Mohamed, A. (2014) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2014.892530 · Cited by 52 · see citing works
Ma, J., Yank, V., Lv, N., Goldhaber-Fiebert, J. D., Lewis, M. A., Kramer, M. K., Snowden, M. B., Rosas, L. G., Xiao, L., & Blonstein, A. C. (2015) · Contemporary Clinical Trials · doi:10.1016/j.cct.2015.06.010 · Cited by 45 · see citing works
Patterns and frequency of the treatment of depression in persons with epilepsy
Fiest, K. M., Patten, S. B., Altura, K. C., Bulloch, A. G. M., Maxwell, C. J., Wiebe, S., Macrodimitris, S. D., & Jetté, N. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.08.023 · Cited by 43 · see citing works
Noble, A. J., Reilly, J., Temple, J., & Fisher, P. (2018) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2018-317997 · Cited by 43 · see citing works
Depression in Homebound Older Adults: Recent Advances in Screening and Psychosocial Interventions
Choi, N. G., Sirey, J. A., & BRUCE, M. L. (2012) · Current Translational Geriatrics and Experimental Gerontology Reports · doi:10.1007/s13670-012-0032-3 · Cited by 42 · see citing works
Pandey, D. K., Levy, J., Serafini, A., Habibi, M., Song, W., Shafer, P. O., & Loeb, J. A. (2019) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2019.07.042 · Cited by 38 · see citing works
Psychological treatments for people with epilepsy
Michaelis, R., Tang, V., Nevitt, S. J., Wagner, J. L., Modi, A. C., LaFrance Jr, W. C., Goldstein, L. H., Gandy, M., Bresnahan, R., Valente, K., et al. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012081.pub3 · Cited by 37 · see citing works
Collaborative care for depression in medically ill patients
Baumeister, H., & Hutter, N. (2012) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e3283556c63 · Cited by 36 · see citing works
Sukhato, K., Lotrakul, M., Dellow, A., Ittasakul, P., Thakkinstian, A., & Anothaisintawee, T. (2017) · BMJ Open · doi:10.1136/bmjopen-2016-014499 · Cited by 35 · see citing works
Trinka, E. (2012) · Acta Neurologica Scandinavica · doi:10.1111/ane.12015 · Cited by 30 · see citing works
Toward an Integrated Public Health Approach for Epilepsy in the 21st Century
Koh, H. K., Kobau, R., Whittemore, V., Mann, M. Y., Johnson, J. G., Hutter, J. D., & Jones, W. K. (2014) · Preventing Chronic Disease · doi:10.5888/pcd11.140270 · Cited by 28 · see citing works
Zheng, Y., Ding, X., Guo, Y. C., Chen, Q., Wang, W., Zheng, Y., Wang, S., Ding, Y., & Ding, M. (2019) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2019.07.001 · Cited by 26 · see citing works
Shegog, R., & Begley, C. E. (2017) · Frontiers in Public Health · doi:10.3389/fpubh.2017.00256 · Cited by 25 · see citing works
Comorbidity of Epilepsy and Depression: Associated Pathophysiology and Management
Alhashimi, R., Thoota, S., Ashok, T., Palyam, V., Azam, A. T., Odeyinka, O., & Sange, I. (2022) · Cureus · doi:10.7759/cureus.21527 · Cited by 25 · see citing works
Sahoo, S. S., Zhang, G., Bamps, Y. A., Fraser, R., STOLL, S. C., Lhatoo, S. D., Tatsuoka, C. M., Sams, J., Welter, E., & Sajatovic, M. (2015) · Health Informatics Journal · doi:10.1177/1460458215572924 · Cited by 24 · see citing works
Self-citationCounseling and Management of the Risks of Living With Epilepsy
Noe, K. H. (2019) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000708 · Cited by 22 · see citing works
Implementation of psychological clinical trials in epilepsy: Review and guide
Modi, A. C., Wagner, J. L., Smith, A. W., Kellermann, T. S., & Michaelis, R. (2017) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2017.06.016 · Cited by 20 · see citing works
Chen, E., Sajatovic, M., Liu, H., Bukach, A. M., Tatsuoka, C. M., Welter, E., Schmidt, S. S., Bamps, Y. A., STOLL, S. C., Spruill, T. M., et al. (2018) · Journal of Clinical Neurology · doi:10.3988/jcn.2018.14.2.206 · Cited by 19 · see citing works
Self-citationSteinman, L. E., Cristofalo, M. A., & Snowden, M. B. (2012) · Preventing Chronic Disease · doi:10.5888/pcd9.110250 · Cited by 15 · see citing works
Baniya, G. C., & Verma, K. (2021) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2021.108488 · Cited by 14 · see citing works
Randolph, J. J., & Chaytor, N. S. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6605-5_5 · Cited by 11 · see citing works
Self-citationPines, A. R., Sacchet, M. D., Kullar, M., Ma, J., & Williams, L. M. (2018) · Scientific Reports · doi:10.1038/s41598-018-32394-2 · Cited by 10 · see citing works
Smith, M. L., Steinman, L. E., Montoya, C. N., Thompson, M., Zhong, L., & Merianos, A. L. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1169257 · Cited by 9 · see citing works
News from the CDC: translating epilepsy self-management research to practice
Kobau, R., Price, P. H., & Hawkins, N. A. (2012) · Translational Behavioral Medicine · doi:10.1007/s13142-012-0122-y · Cited by 9 · see citing works
Psychische Störungen bei somatischen Krankheiten
Kapfhammer, H. P. (2011) · Springer eBooks · doi:10.1007/978-3-642-03637-8_76 · Cited by 7 · see citing works
Psychische Störungen bei somatischen Krankheiten
Kapfhammer, H. (2017) · Springer eBooks · doi:10.1007/978-3-662-49295-6_88 · Cited by 6 · see citing works
Epilepsy and psychological interventions: A systematic review study
Saadat, S., Sheykhangafshe, F. B., Eghbali, B. B., Khatami, S. S., & Isanazar, A. (2022) · Romanian Journal of Neurology · doi:10.37897/rjn.2022.1.3 · Cited by 6 · see citing works
Majd, M., Smyth, J. M., Lv, N., Xiao, L., Snowden, M. B., Venditti, E. M., Williams, L. M., Ajilore, O., Suppes, T. M., & Ma, J. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.11.105 · Cited by 6 · see citing works
Santos, M. M. (2013) · Cited by 6 · see citing works
Development and Evaluation of a Fidelity Instrument for PEARLS
Farren, L., Snowden, M. B., Steinman, L. E., & Monroe‐DeVita, M. (2015) · Frontiers in Public Health · doi:10.3389/fpubh.2014.00200 · Cited by 5 · see citing works
Kapfhammer, H. (2014) · Neuropsychiatrie · doi:10.1007/s40211-014-0105-y · Cited by 4 · see citing works
Ogunjimi, L. O., Joseph, Y., Makanjuola, A., Alabi, A., Aderonke, A., Bamidele, O., Oboh, D., Olusola‐Bello, M., Bolanle, F. O., Abdullahi, M., et al. (2023) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-023-00631-9 · Cited by 4 · see citing works
Depression und neurologische Erkrankungen
Piber, D., Hinkelmann, K., Gold, S. M., Heesen, C., Spitzer, C., Endres, M., & Otte, C. (2012) · Der Nervenarzt · doi:10.1007/s00115-012-3674-7 · Cited by 4 · see citing works
Bridging the divide between epilepsy and mental health to drive solutions
Kobau, R., Manderscheid, R., Owens, S., LaFrance, W. C., Jr., & Sajatovic, M. (2019) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2019.106576 · Cited by 4 · see citing works
Randolph, J. J., & Chaytor, N. S. (2022) · Springer eBooks · doi:10.1007/978-3-031-11389-5_7 · Cited by 4 · see citing works
Self-citationTranslating PEARLS: Lessons Learned from Providers and Participants
Snowden, M. B., Steinman, L. E., Piering, P., Rigor, S., & Yip, A. L. (2015) · Frontiers in Public Health · doi:10.3389/fpubh.2014.00256 · Cited by 4 · see citing works
Service delivery, behavioural, and self-management interventions for adults with epilepsy.
Huang, Y., Nevitt, S., Mayer, J., Fleeman, N., Hill, R. A., Doherty, A., Wilson, N., Boland, P., Clegg, A. J., Bilsborough, H., et al. (2025) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd015284.pub2 · Cited by 2 · see citing works
Rao, J. K., & Anderson, L. A. (2012) · Preventing Chronic Disease · doi:10.5888/pcd9.120110 · Cited by 3 · see citing works
A 15-year snapshot of the behavioral and psychosocial aspects of epilepsy
Wagner, J. L. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.09.030 · Cited by 3 · see citing works
Community Treatment of Older Adults
Carlson, W. L., & Snowden, M. B. (2014) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2014.04.010 · Cited by 3 · see citing works
A common vision and the power of collaboration: The Managing Epilepsy Well Network (MEW)
Jobst, B. C. (2017) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2017.01.023 · Cited by 3 · see citing works
Li, C., Chen, J., Tan, J., Xiao, Y., Deng, R., & Huang, H. (2024) · PLoS ONE · doi:10.1371/journal.pone.0305547 · Cited by 2 · see citing works
Suicide in Children and Adults with Epilepsy: A Complex Relationship
Jones, J. E., & Bordenave, J. M. (2018) · Springer eBooks · doi:10.1007/978-3-319-74391-2_6 · Cited by 2 · see citing works
Psychische Störungen bei somatischen Krankheiten
Kapfhammer, H. (2015) · Springer eBooks · doi:10.1007/978-3-642-45028-0_88-1 · Cited by 2 · see citing works
Gulstrom, C. (2013) · UC Merced Undergraduate Research Journal · doi:10.5070/m451020755 · Cited by 1 · see citing works
Galtrey, C. M., & Cock, H. R. (2015) · Neuropsychiatric symptoms of neurological disease · doi:10.1007/978-3-319-22159-5_15 · Cited by 1 · see citing works
El-Hagrassy, M. M., Teixeira-Santos, A. C., & Fregni, F. (2018) · Neuromethods · doi:10.1007/978-1-4939-7880-9_13 · Cited by 1 · see citing works
Motlagh, L. V., Hosseini, S. M., Najafi, M., & Taki, G. Z. G. (2020) · کومش · doi:10.29252/koomesh.22.3.419 · Cited by 1 · see citing works
Epilepsy Foundation efforts to reduce the impact of epilepsy-related comorbidities: We cannot wait
Gattone, P. M. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.02.022
Quality of Life for Epileptics
McCandless, D. W. (2011) · Epilepsy · doi:10.1007/978-1-4614-0361-6_39
Non-Pharmacologic Management of Epilepsy
Krishnamoorthy, E. S., Shorvon, S. D., & Schachter, S. C. (2017) · Epilepsy · doi:10.1017/9781139547918.033
Petrescu-Prahova, M. G., Steinman, L. E., Dronen, A., Rigor, S., & Snowden, M. B. (2017) · Military Behavioral Health · doi:10.1080/21635781.2017.1316805
La depressione nell'epilessia. Cause, diagnosi e trattamento
D’Amico, R. (2018) · PSICOLOGIA DELLA SALUTE · doi:10.3280/pds2018-003002
Endermann, M. (2018) · Clinical Epileptology · doi:10.1007/s10309-018-0221-y
Sarudianky, M. (2019) · Redalyc (Universidad Autónoma del Estado de México)
Meta-Analysis of Effectiveness of Psychosocial Treatment Programs in Epilepsy
Ghosh, R., & Baruah, A. (2023) · Indian Journal of Social Psychiatry · doi:10.4103/ijsp.ijsp_75_22
Armah, L., Tan, L., Branning, R., Ghearing, G. R., Tyrrell, M., Fiorelli, N. M., Black, J., Krehel-Montgomery, J., Adeniyi, C., Sajatovic, M., et al. (2026) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2026.111117
Sun, Y., Wang, J., Guan, Y., & Wu, Z. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1917962
Enhancing quality of mental health service for veterans with seizures
Lopez, M., LaFrance, W. C., Jr., Mordecai, K. L., Blanken, A. E., Pugh, M. J., Ocier, K., & Altalib, H. H. (2026) · Epilepsia · doi:10.1002/epi.70443
- Authors
- Chaytor, N., Ciechanowski, P., Miller, J. W., Fraser, R., Russo, J., Unutzer, J., & Gilliam, F.
- Affiliations
- University of Washington (US)
- Geisinger Health System (US)
- Corresponding author
- Chaytor, Naomi
- Venue
- Epilepsy & Behavior
- Publisher
- Elsevier BV
- Published
- 2011-03
- Volume
- 20
- Issue
- 3
- Pages
- 545-549
- ISSN
- 1525-5050 (ISSN-L)
- OpenAlex
- W2107265032
- Cited by
- 76
- References
- 27
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 3 · 2020: 3 · 2019: 5 · 2018: 9 · 2017: 10 · 2016: 2 · 2015: 7 · 2014: 9 · 2013: 6 · 2012: 9
- FWCI
- 5.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Epilepsy & Behavior (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (K24NS047551, R01NS040808)
- National Center for Chronic Disease Prevention and Health Promotion (U48-DP000050)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Epilepsy research and treatment
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- depression, epilepsy, problem-solving therapy, behavioral activation, psychiatric consultation, suicidal ideation, emotional well-being, quality of life, long-term treatment effectiveness, usual care comparison
- MeSH terms
- Adult, Depression, Emotions, Epilepsy, Female, Home Care Services, Humans, Longitudinal Studies, Male, Middle Aged, Psychiatric Status Rating Scales, Quality of Life, Suicide, Time Factors, Treatment Outcome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
