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NLRP3 inflammasome and gut microbiota–brain axis: A new perspective on white matter injury after intracerebral hemorrhage

Cai, X., Cai, X., Xie, Q., Xiao, X., Li, T., Zhou, T., & Sun, H. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-00917 · Cited by 26 · see citing works

P2X7 receptor as the regulator of T-cell function in intestinal barrier disruption

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Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos

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Development of a novel Cas13a/Cas12a-mediated 'one-pot' dual detection assay for genetically modified crops

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Inflammation unleashed: The role of pyroptosis in chronic liver diseases

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Involvement of role of HMGB1-NLRP3 pathway in systemic disorders

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Sterile Inflammation and Cell Death Pathways in Liver Ischemia-Reperfusion Injury: A Review and Perspective

Huang, W., Meng, W., Zhao, J., & Zhang, B. (2025) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/0118715303401342250514102731 · Cited by 16 · see citing works

Inflammasome signalling pathway in the regulation of inflammation – its involvement in the development and exacerbation of asthma and chronic obstructive pulmonary disease

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Toll-Like Receptor-Mediated Activation of CD39 Internalization in BMDCs Leads to Extracellular ATP Accumulation and Facilitates P2X7 Receptor Activation

Zhao, R., Qiao, J., Zhang, X., Zhao, Y., Meng, X., Sun, D., & Peng, X. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02524 · Cited by 14 · see citing works

Effect of miR-506-3p on Proliferation and Apoptosis of Airway Smooth Muscle Cells in Asthmatic Mice by Regulating CCL2 Gene Expression and Mediating TLR4/NF-κB Signaling Pathway Activation

Man-li, W., & Hua, Q. (2021) · Molecular Biotechnology · doi:10.1007/s12033-021-00309-8 · Cited by 13 · see citing works

An overview of high-mobility group box 1, a potent pro-inflammatory cytokine in asthma

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Assessment of toxicological effects of favipiravir (T‐705) on the lung tissue of rats: An experimental study

Erbaş, E., Celep, N. A., Tekiner, D., Genç, A., & Gedikli, S. (2023) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.23536 · Cited by 10 · see citing works

Inflammasomes and idiopathic inflammatory myopathies

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Phasic regulation of the ATP/P2X7 receptor signaling pathway affects the function of antigen-presenting cells in experimental autoimmune uveitis

Peng, X., Zhang, Y., Bai, X., Li, X., & Zhao, R. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110241 · Cited by 8 · see citing works

A Species-Specific Anti-Human P2X7 Monoclonal Antibody Reduces Graft-versus-Host Disease in Humanised Mice

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Immune Response Studies Based on P2X7 Receptors: A Mini-Review

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Advances in the Understanding of Mitochondrial Inflammatory Regulation in the Pathogenesis of Alzheimer’s Disease

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NOD2-NLRP3 Axis and Asthma

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MicroRNA-19a Inhibition Directly and Indirectly Ameliorates Th2 Airway Inflammation in Asthma by Targeting RUNX3

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Pedunculoside targets P2X7R to protect against myocarditis by regulating the NLRP3/PIP2/MAPK signaling pathway

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Extracellular adenosine triphosphate: A new gateway for food allergy mechanism research?

Zhang, X., Chen, X., Meng, X., Wu, Y., Gao, J., Chen, H., & Li, X. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.141821 · Cited by 6 · see citing works

The role of ion channels in the regulation of dendritic cell function

Zhou, S.-L., Zhong, L., Wu, Y.-L., Ji, S.-W., Li, Y., & Niu, N. (2025) · Cell Calcium · doi:10.1016/j.ceca.2025.103031 · Cited by 6 · see citing works

A novel fluorescent recombinant cell-based biosensor for screening NLRP3 inflammasome inhibitors

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Screening, identification and targeted intervention of necroptotic biomarkers of asthma

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NOD3 Reduces Sepsis-Induced Acute Lung Injury by Regulating the Activation of NLRP3 Inflammasome and the Polarization of Alveolar Macrophages

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Reducing Luminal Extracellular Adenosine Triphosphate Levels Alleviates Food Allergy Induced by an Egg White Diet in Mice

Zhang, X., Chen, X., Bai, T., Meng, X., Wu, Y., Yang, A., Min, L., Chen, H., & Li, X. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c12844 · Cited by 5 · see citing works

Cross Talk of Purinergic and Immune Signaling: Implication in Inflammatory and Pathogenic Diseases

Rai, R. (2022) · Biochemistry · doi:10.5772/intechopen.104978 · Cited by 5 · see citing works

The effects of NLRP3 and MAVS gene polymorphisms on the risk of asthma: A case–control study

Cai, X., Li, Z., & Tongjin, Y. (2022) · Medicine · doi:10.1097/md.0000000000032385 · Cited by 5 · see citing works

Amplification-free, CRISPR-Cas12a-mediated fluorescence biosensor using mesoporous silica nanomaterials for ultrasensitive detection of nucleic acid biomarkers

Feng, L., Cheng, A.-X., Zhang, C., Li, J., Huang, Y.-F., Zhang, Y., Li, C.-P., & Zhao, H. (2025) · Talanta · doi:10.1016/j.talanta.2025.129289 · Cited by 4 · see citing works

Alterations of the gut microbial community structure modulates the Th17 cells response in a rat model of asphyxial cardiac arrest

Yuan, Q., Sun, L., Ma, G., Shen, H., Wang, S., Guo, F., Sun, X., & Gao, C. (2023) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2023.101543 · Cited by 4 · see citing works

Review on the Mechanism of and Therapies Targeting PANoptosis in Ulcerative Colitis

Zhao, M., LIU, M., Tian, W., Ren, T., Jing, J., Zheng, Y., & Chen, Z. (2026) · Biomolecules · doi:10.3390/biom16050624 · Cited by 4 · see citing works

Emerging targets signaling for inflammation in Parkinson’s disease drug discovery

Khairnar, R. C., Parihar, N., Prabhavalkar, K. S., & Bhatt, L. K. (2022) · Metabolic Brain Disease · doi:10.1007/s11011-022-00999-2 · Cited by 3 · see citing works

Association between PLA2G4A and P2RX7 genes and eosinophilic phenotype and environment with pediatric asthma

Ren, M., Li, L., Jia, J., & Wei, B. (2023) · Gene · doi:10.1016/j.gene.2023.147182 · Cited by 3 · see citing works

Purinergic Receptors in Dendritic Cells

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P2X receptors in immune cells: key regulators of inflammation and immune function

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Unveiling the role of resident memory T cells in psoriasis

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P2X7 receptor contributes to DNA damage repair and acquisition of malignant phenotypes in irradiated human glioblastoma cells

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Investigation of the mechanistic impact of CBL0137 on airway remodeling in asthma

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P2X7 receptor: a potential therapeutic target for chronic respiratory diseases

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Nanophotodynamic therapy and immunotherapy combination

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Adeno‐associated viral vectors encoding anti‐P2X7 nanobodies reduce graft‐versus‐host disease in a humanised mouse model

Elhage, A., Hadaya, J. H., Sligar, C., Watson, D., Adriouch, S., & Sluyter, R. (2025) · Clinical & Translational Immunology · doi:10.1002/cti2.70061 · Cited by 1 · see citing works

Distribution Characteristics and Functional Prediction of NLRP3 Polymorphism in Children with Allergic Rhinitis

Cai, X., Yin, T., Wang, J., & Mu, Q. (2025) · International Archives of Allergy and Immunology · doi:10.1159/000547060

Extracellular ATP and the normal respiratory system

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Comparative Pharmacology of Caspase‐1 Inhibitors: Ac‐YVAD‐CMK, Z‐YVAD‐FMK, and Ac‐YVAD‐CHO in Multisystem Diseases

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ATP/P2X7 signaling as a potential predictive biomarker for early recurrence of nasal polyps: Correlation with inflammasome activation and epithelial barrier dysfunction

Yang, L., Chen, Y., Shi, T., & Liu, Q. (2026) · World Allergy Organization Journal · doi:10.1016/j.waojou.2026.101455

BindingDB Entry 50023323: Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor.

BindingDB (2026) · UC San Diego · doi:10.7270/q22f7tc7

IL-27 Alleviates Airway Inflammation and Airway Hyperresponsiveness in Asthmatic Mice by Targeting the CD39/ATP Axis of Dendritic Cells

Chen, Y., Zhu, M., Hu, J., He, S., Li, S., Liu, B., & Yang, J. (2023) · Inflammation · doi:10.1007/s10753-023-01945-9 · Cited by 5 · see citing works

HMGB1-induced ILC2s activate dendritic cells by producing IL-9 in mice asthma

Xu, H., Wan, J., Su, Z., & Wang, S. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.202.supp.60.1

HMGB1 regulates T helper 2 and T helper17 cell differentiation both directly and indirectly in asthmatic mice

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ATP/P2X7r axis mediates the pathological process of allergic asthma by inducing M2 polarization of alveolar macrophages

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Recombinant HMGB1 A box protein inhibits Th17 responses in mice with neutrophilic asthma by suppressing dendritic cell-mediated Th17 polarization

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