The DOI matches its Crossref record; 91 of the 91 references it cites were found in a registry or an index.
Formation and Intracellular Trafficking of Lipoplexes and Polyplexes
Open accessAbstract
Cationic lipid/DNA lipoplexes and cationic polymer/DNA polyplexes represent an attractive alternative to viral vectors for cell transfection in vitro and in vivo but still suffer from a relatively low efficiency. Optimization of their transfection efficiency may be attempted by using a trial and error approach consisting of synthesizing and testing a large number of derivatives. On the other hand, rational design of highly efficient cationic lipids and polymers requires a deeper understanding of the interactions between the vector and the DNA as well as the cellular pathways and mechanisms involved in DNA entry into the cell and ultimately the nucleus. In the present review, the pathways and mechanisms involved in lipoplex- and polyplex-mediated transfection are comparatively addressed and unresolved questions are highlighted.
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Toxicity of cationic lipids and cationic polymers in gene delivery
Lv, H., Zhang, S., Wang, B., Cui, S., & Yan, J. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.04.014 · Cited by 2,286
Natural Polymers for Gene Delivery and Tissue Engineering
DANG, J., & LEONG, K. (2006) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2006.03.001 · Cited by 694
Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown
Wittrup, A., Ai, A., Liu, X., Hamar, P., Trifonova, R., Charisse, K., Manoharan, M., Kirchhausen, T., & Lieberman, J. (2015) · Nature Biotechnology · doi:10.1038/nbt.3298 · Cited by 693
Multifunctional and stimuli-sensitive pharmaceutical nanocarriers
Torchilin, V. (2009) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2008.09.026 · Cited by 583
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Metadata
- Authors
- Elouahabi, A., & Ruysschaert, J.-M.
- Venue
- Molecular Therapy
- Publisher
- Elsevier BV
- Published
- 2005-03
- Volume
- 11
- Issue
- 3
- Pages
- 336-347
- ISSN
- 1525-0016 (ISSN-L)
- OpenAlex
- W2071732315
- Cited by
- 462
- References
- 91
- FWCI
- 7.38
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Elouahabi, A., & Ruysschaert, J.-M. (2005). Formation and Intracellular Trafficking of Lipoplexes and Polyplexes. Molecular Therapy. https://doi.org/10.1016/j.ymthe.2004.12.006
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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