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Physical activity and decreased risk of clinical gallstone disease among post-menopausal women

Storti, Kristi L., Brach, Jennifer S., FitzGerald, Shannon J., Zmuda, Joseph M., Cauley, Jane A., Kriska, Andrea M.·2005·Preventive Medicine
DOI 10.1016/j.ypmed.2005.04.002
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Abstract

Background Physical activity may play a role in preventing gallstone disease. Methods The activity/gallstone relationship was examined in post-menopausal women from the Study of Osteoporotic Fractures (SOF; 1986-1988), a prospective study of fracture risk factors in 8010 women (mean age = 71.1 years, SD = 4.9). Results Multivariate logistic regression indicated women in the lowest two quartiles of physical activity, according to questionnaire, had a 59% {OR = 1.59 (1.11-2.29), P = 0.02} and a 57% higher risk {OR = 1.57 (1.11-2.23), P = 0.01} of developing gallstone disease compared to women in the highest quartile of activity (PTrend = Conclusion Physical activity appears to be inversely related to the development of gallstone disease in post-menopausal women independent of body mass index.

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Crossref · 10.1016/j.ypmed.2005.04.002

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  • In obese women without gallstones randomized to omega-3 fatty acids, UDCA, or placebo for 6 weeks, no reduction of biliary cholesterol saturation was observed, and none developed gallstones during the intervention.

    “Another study in obese women without gallstones who were randomized to receiving omega-3 fatty acids or UDCA or placebo for 6 weeks did not observe a reduction of biliary cholesterol saturation, despite the fact that none of the participants developed gallstones during this intervention period [74].”

    From Excess Body Weight and Gallstone Disease (2021) · cites this paper as [74]

Citations

Cites

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Research works printed but not linked: 37

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Metadata

Authors
Storti, K. L., Brach, J. S., FitzGerald, S. J., Zmuda, J. M., Cauley, J. A., & Kriska, A. M.
Venue
Preventive Medicine
Publisher
Elsevier BV
Published
2005-09
Volume
41
Issue
3-4
Pages
772-777
ISSN
0091-7435
DOI
10.1016/j.ypmed.2005.04.002
Cited by
31
References
2
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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