The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Cervical Epithelial Cells Transduced with the Papillomavirus E6/E7 Oncogenes Maintain Stable Levels of Oncoprotein Expression but Exhibit Progressive, Major Increases in hTERT Gene Expression and Telomerase Activity
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Previous data have indicated that induction of hTERT by HPV-16 E6 may involve epigenetic phenomenon such as histone acetylation or chromatin remodeling (Klingelhutz et al. 1996; Kiyono et al. 1998; Baege et al. 2002).”
From Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complex (2004) · cites this paper as Baege et al. 2002
In the citing paper
“Although cMyc levels do not appear to change dramatically on E6 expression (Gewin and Galloway 2001; Veldman et al. 2001), two groups have recently found by chromatin immunoprecipitation that c-Myc is bound to the hTERT promoter in E6-expressing cells (Baege et al. 2002; Veldman et al. 2003).”
From Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complex (2004) · cites this paper as Baege et al. 2002
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Kiyono, T., Foster, S. A., Koop, J. I., McDougall, J. K., Galloway, D. A., & Klingelhutz, A. J. (1998) · Nature · doi:10.1038/23962 · Cited by 1,206
Huibregtse, J. M., Scheffner, M., & Howley, P. M. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb04990.x · Cited by 879
Kunimura, C., Kikuchi, K., Ahmed, N., Shimizu, A., & Yasumoto, S. (1998) · Oncogene · doi:10.1038/sj.onc.1201916 · Cited by 50
Research works printed but not linked: 30
- zsn, 1996, Papillomavirus infections—a major cause of human cancerxs, Biochem Biophys Acta, 1288, 55
- zur Hausen, 2000, Papillomavirus causing cancer: evasion from host-cell control in early events in carcinogenesis, J Natl Cancer Inst, 92, 690, 10.1093/jnci/92.9.690 · DOI
- Dyson, 1989, The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product, Science, 243, 934, 10.1126/science.2537532 · DOI · Paper page
- Münger, 1989, Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product, EMBO J, 8, 4099, 10.1002/j.1460-2075.1989.tb08594.x · DOI · Paper page
- Scheffner, 1990, The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53, Cell, 63, 1129, 10.1016/0092-8674(90)90409-8 · DOI · Paper page
- Sherman, 1996, Serum- and calcium-induced differentiation of human keratinocytes is inhibited by the E6 oncoprotein of human papillomavirus type 16, J Virol, 70, 3269, 10.1128/jvi.70.5.3269-3279.1996 · DOI
- Münger, 1989, The E6 and E7 genes of human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes, J Virol, 63, 4417, 10.1128/jvi.63.10.4417-4421.1989 · DOI · Paper page
- Schlegel, 1988, Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma, EMBO J, 7, 3181, 10.1002/j.1460-2075.1988.tb03185.x · DOI · Paper page
- Takakura, 1998, Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer, Cancer Res, 58, 1558
- Snijders, 1998, Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high risk human papillomavirus DNA, Cancer Res, 58, 3812
- Bodnar, 1998, Extension of life span by introduction of telomerase into normal human cells, Science, 279, 349, 10.1126/science.279.5349.349 · DOI · Paper page
- Counter, 1998, Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit telomerase, Oncogene, 16, 1217, 10.1038/sj.onc.1201882 · DOI
- Klingelhutz, 1996, Telomerase activation by the E6 gene product of human papillomavirus type 16, Nature, 380, 79, 10.1038/380079a0 · DOI · Paper page
- Veldman, 2001, Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein, J Virol, 75, 4467, 10.1128/JVI.75.9.4467-4472.2001 · DOI · Paper page
- Gewin, 2001, E box-dependent activation of telomerase by human papillomavirus type 16 E6 does not require induction of c-myc, J Virol, 75, 7198, 10.1128/JVI.75.15.7198-7201.2001 · DOI · Paper page
- Kim, 1994, Specific association of human telomerase with immortal cells and cancer, Science, 266, 2011, 10.1126/science.7605428 · DOI · Paper page
- Anderson, 1997, Telomerase activation in cervical cancer, Am J Pathol, 151, 25
- Nees, 2001, Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappa-responsive genes in cervical keratinocytes, J Virol, 75, 4283, 10.1128/JVI.75.9.4283-4296.2001 · DOI
- Nakamura, 1997, Telomerase catalytic subunit homologs from fission yeast and human, Science, 277, 955, 10.1126/science.277.5328.955 · DOI · Paper page
- Laborda, 1991, 36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO, Nucl Acid Res, 19, 3998, 10.1093/nar/19.14.3998 · DOI
- Stöppler, 1997, The human papillomavirus type 16 E6 and E7 oncoproteins dissociate cellular telomerase activity from the maintenance of telomere length, J Biol Chem, 272, 13332, 10.1074/jbc.272.20.13332 · DOI
- Steenbergen, 1996, Transition of human papillomavirus type 16 and 18 transfected human foreskin keratinocytes towards immortality: activation of telomerase and allele losses at 3p, 10p, 11p, 11q and/or 18q, Oncogene, 13, 1249
- Oh, 2001, Telomerase activation by human papillomavirus type 16 E6 protein: induction of human telomerase reverse transcriptase expression through myc and GC-rich sp1 binding sites, J Virol, 75, 5559, 10.1128/JVI.75.12.5559-5566.2001 · DOI · Paper page
- Blasco, 1996, Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis, Nat Genet, 12, 200, 10.1038/ng0296-200 · DOI
- Wisman, 2001, Telomerase in relation to clinicopathologic prognostic factors and survival in cervical cancer, Int J Cancer, 91, 658, 10.1002/1097-0215(200002)9999:9999<::AID-IJC1099>3.0.CO;2-7 · DOI
- Yasumoto, 1996, Telomerase activity in normal human epithelial cells, Oncogene, 13, 433
- Riethdorf, 2001, Relationship between telomerase activation and HPV 16/18 oncogene expression in squamous intraepithelial lesions and squamous cell carcinomas of the uterine cervix, Int J Gynecol Pathol, 20, 177, 10.1097/00004347-200104000-00011 · DOI
- Wisman, 1998, Telomerase activity as a biomarker for (pre)neoplastic cervical disease in scrapings and frozen sections from patients with abnormal cervical smears, J Clin Oncol, 16, 2238, 10.1200/JCO.1998.16.6.2238 · DOI
- Yashima, 1998, Telomerase activity and expression of its RNA component in cervical lesions, Cancer, 82, 1319, 10.1002/(SICI)1097-0142(19980401)82:7<1319::AID-CNCR15>3.0.CO;2-9 · DOI
- Multirangura, 1998, Telomerase activity and human papillomavirus in malignant, premalignant and benign cervical lesions, Br J Cancer, 78, 933, 10.1038/bjc.1998.604 · DOI
Cited by
Gewin, L., Myers, H., Kiyono, T., & Galloway, D. A. (2004) · Genes & Development · doi:10.1101/gad.1214704 · Cited by 277
Horikawa, I., & Barrett, J. C. (2003) · Carcinogenesis · doi:10.1093/carcin/bgg085 · Cited by 211
Metadata
- Authors
- Baege, A. C., Berger, A., Schlegel, R., Veldman, T., & Schlegel, R.
- Venue
- The American Journal of Pathology
- Publisher
- Elsevier BV
- Published
- 2002-04
- Volume
- 160
- Issue
- 4
- Pages
- 1251-1257
- ISSN
- 0002-9440
- Cited by
- 41
- References
- 3
- Language
- en
- Funders
- National Institutes of Health (R01CA53371)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review