Free radicals and tissue damage produced by exercise

Methods in Enzymology , Vol

Colowick, S. P., Joshi, M. D., Jagannathan, & KAPLAN, N. O. (1966) · Cited by 26,137

Hydroperoxide metabolism in mammalian organs.

Chance, B., Sies, H., & Boveris, A. (1979) · Physiological Reviews · doi:10.1152/physrev.1979.59.3.527 · Cited by 5,827

Free Radicals in Biology

Pryor, W. A. (1976) · Cited by 1,876

Biochemical Adaptations in Muscle

Holloszy, J. O. (1967) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)96046-1 · Cited by 1,517

Superoxide, hydrogen peroxide, and singlet oxygen in lipid peroxidation by a xanthine oxidase system.

Kellogg, E. W., & Fridovich, I. (1975) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)40745-x · Cited by 966

Effects of exercise, vitamin E, and ozone on pulmonary function and lipid peroxidation

Dillard, C. J., Litov, R. E., SAVIN, W. M., Dumelin, E. E., & Tappel, A. L. (1978) · Journal of Applied Physiology · doi:10.1152/jappl.1978.45.6.927 · Cited by 561

Biochemical adaptation of mitochondria, muscle, and whole-animal respiration to endurance training

Davies, K. J. A., Packer, L., & Brooks, G. A. (1981) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(81)90312-x · Cited by 430

Effect of exercise and training on mitochondria of rat skeletal muscle

Gollnick, P., & King, D. S. (1969) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1969.216.6.1502 · Cited by 280

Temperature, skeletal muscle mitochondrial functions, and oxygen debt

Brooks, G., Hittelman, K., Faulkner, J., & Beyer, R. (1971) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1971.220.4.1053 · Cited by 261

Effect of exercise on synthesis and degradation of muscle protein

Dohm, G. L., Kasperek, G. J., Tapscott, E. B., & Beecher, G. R. (1980) · Biochemical Journal · doi:10.1042/bj1880255 · Cited by 145

Intracellular proteolytic systems may function as secondary antioxidant defenses: An hypothesis

Davies, K. J. A. (1986) · Journal of Free Radicals in Biology & Medicine · doi:10.1016/s0748-5514(86)80066-6 · Cited by 276

Effect of Vitamin C Supplements on Antioxidant Defence and Stress Proteins in Human Lymphocytes and Skeletal Muscle

Khassaf, M. B., McArdle, A., Esanu, C., Vasilaki, A., McArdle, F., Griffiths, R. D., Brodie, D. A., & Jackson, M. J. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.040303 · Cited by 273

The effect of exercise training on oxidative damage of lipids, proteins, and DNA in rat skeletal muscle: evidence for beneficial outcomes

Radak, Z. O., Kaneko, T., Tahara, S., Nakamoto, H., Ohno, H., Sasvári, M., Nyakas, C. J., & Goto, S. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00038-6 · Cited by 273

Exercise-induced lipid peroxidation and leakage of enzymes before and after vitamin E supplementation

Sumida, S., Tanaka, K., Kitao, H., & Nakadomo, F. (1989) · International Journal of Biochemistry · doi:10.1016/0020-711x(89)90280-2 · Cited by 272

Oxidative stress associated with exercise, psychological stress and life-style factors

Møller, P., Wallin, H., & Knudsen, L. E. (1996) · Chemico-Biological Interactions · doi:10.1016/0009-2797(96)03729-5 · Cited by 270

Mitochondrial physiology and pathology; concepts of programmed death of organelles, cells and organisms

Skulachev, V. P. (1999) · Molecular Aspects of Medicine · doi:10.1016/s0098-2997(99)00008-4 · Cited by 272

Exercise and endothelial function: Role of endothelium-derived nitric oxide and oxidative stress in healthy subjects and hypertensive patients

Higashi, Y., & Yoshizumi, M. (2004) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2004.02.003 · Cited by 271

The aging process and potential interventions to extend life expectancy.

Tosato, M., Zamboni, V., Ferrini, A., & Cesari, M. (2007) · PubMed Central · Cited by 260

Blood antioxidant status and erythrocyte lipid peroxidation following distance running

Duthie, G. G., Robertson, J. D., Maughan, R. J., & Morrice, P. C. (1990) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(90)90089-h · Cited by 258

Exercise-induced Quadriceps Oxidative Stress and Peripheral Muscle Dysfunction in Patients with Chronic Obstructive Pulmonary Disease

Couillard, A., Maltais, F., Saey, D., Debigaré, R., Michaud, A., Koechlin‐Ramonatxo, C., Leblanc, P., & PREFAUT, C. G. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200209-1028oc · Cited by 262

ERK1/2 and p38-MAPK signalling pathways, through MSK1, are involved in NF-κB transactivation during oxidative stress in skeletal myoblasts

Kefaloyianni, E., Gaitanaki, C., & Beis, I. D. (2006) · Cellular Signalling · doi:10.1016/j.cellsig.2006.05.004 · Cited by 259

Maximum Strength-Power-Performance Relationships in Collegiate Throwers

STONE, M. H., SANBORN, K., OʼBRYANT, H. S., HARTMAN, M., STONE, M. E., PROULX, C., WARD, B., & HRUBY, J. (2003) · Journal of Strength and Conditioning Research · doi:10.1519/00124278-200311000-00019 · Cited by 254

Mitochondrial biogenesis in exercise and in ageing☆

Viña, J., Gómez‐Cabrera, M. C., Borrás, C., Froio, T., Sanchis‐Gomar, F., Martinez-Bello, V. E., & Pallardó, F. V. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.06.006 · Cited by 261

Marine Collagen: A Promising Biomaterial for Wound Healing, Skin Anti-Aging, and Bone Regeneration

Geahchan, S., Baharlouei, P., & Rahman, M. A. (2022) · Marine Drugs · doi:10.3390/md20010061 · Cited by 258

An analysis of the role of coenzyme Q in free radical generation and as an antioxidant

Beyer, R. E. (1992) · Biochemistry and Cell Biology · doi:10.1139/o92-061 · Cited by 251

Regulation of antioxidant enzyme gene expression in response to oxidative stress and during differentiation of mouse skeletal muscle

Franco, A. A., Odom, R. S., & Rando, T. A. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00166-5 · Cited by 248

Mitochondrial fatty acid oxidation in obesity

Serra, D., Mera, P., Malandrino, M. I., Mir, J. F., & Herrero, L. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4875 · Cited by 246

Changes in blood lipid peroxidation markers and antioxidants after a single sprint anaerobic exercise

Groussard, C., Rannou‐Bekono, F., Machefer, G., Chevanne, M., Vincent, S., Sergent, O., Cillard, J., & Gratas‐Delamarche, A. (2003) · European Journal of Applied Physiology · doi:10.1007/s00421-002-0767-1 · Cited by 246

Oxidative Stress Responses in Older Men during Endurance Training and Detraining

Fatouros, I. G., Jamurtas, A. Z., Villiotou, V., POULIOPOULOU, S., Foteinakis, P. F., Taxildaris, K., & Deliconstantinos, G. (2004) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000147632.17450.ff · Cited by 246

Vitamin E and C supplementation reduces oxidative stress, improves antioxidant enzymes and positive muscle work in chronically loaded muscles of aged rats

Ryan, M. J., Dudash, H. J., Docherty, M., Geronilla, K. B., Baker, B. A., Haff, G. G., Cutlip, R. G., & Alway, S. E. (2010) · Experimental Gerontology · doi:10.1016/j.exger.2010.08.002 · Cited by 245

Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

Gliemann, L., Schmidt, J. F., Olesen, J., Biensø, R. S., Peronard, S. L., Grandjean, S. U., Mortensen, S. P., Nyberg, M., Bangsbo, J., Pilegaard, H., et al. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2013.258061 · Cited by 244

Free radical theory of aging: Consequences of mitochondrial aging

Harman, D. (1983) · AGE · doi:10.1007/bf02432509 · Cited by 244

Free radical scavenging and antioxidant effects of lactate ion: an in vitro study

Groussard, C., Morel, I., Chevanne, M., Monnier, M., Cillard, J., & Delamarche, A. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.1.169 · Cited by 241

Oxidative stress impairs the function of sarcoplasmic reticulum by oxidation of sulfhydryl groups in the Ca2+-ATPase

Scherer, N. M., & Deamer, D. W. (1986) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(86)90314-0 · Cited by 241

Oxidant, antioxidant and physical exercise

Banerjee, A. K., Mandal, A., Chanda, D., & Chakraborti, S. (2003) · Molecular and Cellular Biochemistry · doi:10.1023/a:1026032404105 · Cited by 240

[51] Protein degradation as an index of oxidative stress

Pacifici, R. E., & Davies, K. J. A. (1990) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(90)86143-j · Cited by 239

Effect of vitamin E and eccentric exercise on selected biomarkers of oxidative stress in young and elderly men

Sacheck, J. M., Milbury, P. E., Cannon, J. G., Roubenoff, R., & Blumberg, J. B. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(03)00187-4 · Cited by 238

Vitamin E, vitamin C, and exercise

Evans, W. J. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.2.647s · Cited by 238

The Role of Oxidative Stress in Skeletal Muscle Myogenesis and Muscle Disease

Lian, D., Chen, M.-M., Wu, H., Deng, S., & Hu, X. (2022) · Antioxidants · doi:10.3390/antiox11040755 · Cited by 232

N -acetylcysteine enhances muscle cysteine and glutathione availability and attenuates fatigue during prolonged exercise in endurance-trained individuals

Medved, I., Brown, M. J., Bjorksten, A. R., Murphy, K. T., Petersen, A. C., Sostaric, S. M., Gong, X., & McKenna, M. J. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00371.2004 · Cited by 232

Superoxide dismutase gene expression is activated by a single bout of exercise in rat skeletal muscle

Hollander, J. M., Fiebig, R., Gore, M. T., Ookawara, T., Ohno, H., & Ji, L. (2001) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s004240100539 · Cited by 231

Muscle-derived ROS and thiol regulation in muscle fatigue

Ferreira, L. F., & Reid, M. B. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00953.2007 · Cited by 230

Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise

Henríquez-Olguin, C., Knudsen, J. R., Raun, S. H., Li, Z., Dalbram, E., Treebak, J. T., Sylow, L., Holmdahl, R., Richter, E. A., Jaimovich, E., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12523-9 · Cited by 228

Physiological roles of muscle-derived interleukin-6 in response to exercise

Pedersen, B. K., & Fischer, C. P. (2007) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e3280ebb5b3 · Cited by 227

Antioxidant supplements and endurance exercise: Current evidence and mechanistic insights

Mason, S. A., Trewin, A. J., Parker, L., & Wadley, G. D. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101471 · Cited by 236

Muscle damage, inflammatory, immune and performance responses to three football games in 1 week in competitive male players

Mohr, M., Draganidis, D., Chatzinikolaou, A., Álvarez, J. C. B., Castagna, C., DOUROUDOS, I. I., Avloniti, A. A., Margeli, A. P., Papassotiriou, I., Flouris, A. D., et al. (2015) · European Journal of Applied Physiology · doi:10.1007/s00421-015-3245-2 · Cited by 253

Short- and long-term alterations of mitochondrial morphology, dynamics and mtDNA after transient oxidative stress

Jendrach, M., Mai, S., Pohl, S., Vöth, M., & Bereiter‐Hahn, J. (2008) · Mitochondrion · doi:10.1016/j.mito.2008.06.001 · Cited by 225

Rigorous exercise training increases superoxide dismutase activity in ventricular myocardium

Powers, S. K., Criswell, D. S., Lawler, J., Martin, D., Lieu, F., Ji, L. L., & Herb, R. A. (1993) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1993.265.6.h2094 · Cited by 223

The role of declining adaptive homeostasis in ageing

Pomatto, L. C. D., & Davies, K. J. A. (2017) · The Journal of Physiology · doi:10.1113/jp275072 · Cited by 231

Acute phase response in exercise. II. Associations between vitamin E, cytokines, and muscle proteolysis

Cannon, J. G., Meydani, S. N., Fielding, R. A., FIATARONE, M. A., Meydani, M., Farhangmehr, M., Orencole, S. F., Blumberg, J. B., & Evans, W. J. (1991) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1991.260.6.r1235 · Cited by 223

Exercise, Oxidative Damage and Effects of Antioxidant Manipulation ,

Witt, E. H., Reznick, A. Z., Viguie, C. A., Starke-Reed, P. E., & Packer, L. (1992) · Journal of Nutrition · doi:10.1093/jn/122.suppl_3.766 · Cited by 221

Carbonic anhydrase III protects cells from hydrogen peroxide‐induced apoptosis

Räisänen, S. R., Lehenkari, P. P., Tasanen, M. J., Rahkila, P., Härkönen, P. L., & Väänänen, H. K. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.3.513 · Cited by 220

Time course of responses of human skeletal muscle to oxidative stress induced by nondamaging exercise

Khassaf, M., Child, R. B., McArdle, A., Brodie, D. A., Esanu, C., & Jackson, M. J. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.3.1031 · Cited by 219

Free radical generation by skeletal muscle of adult and old mice: effect of contractile activity

Vasilaki, A., Mansouri, A., Remmen, H. V., van der Meulen, J. H., Larkin, L. M., Richardson, A. G., McArdle, A., Faulkner, J. A., & Jackson, M. J. (2006) · Aging Cell · doi:10.1111/j.1474-9726.2006.00198.x · Cited by 215

Lipid peroxidation and antioxidative vitamins under extreme endurance stress*

Rokitzki, L., Logemann, E., Sagredos, A. N., MURPHY, M., WETZEL‐ROTH, W., & Keul, J. (1994) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1994.tb09732.x · Cited by 215

Mitochondria in Exercise-Induced Oxidative Stress

Meo, S. D., & Venditti, P. (2001) · Neurosignals · doi:10.1159/000046880 · Cited by 214

Edward F. Adolph Distinguished Lecture: Muscle as an endocrine organ: IL-6 and other myokines

Pedersen, B. K. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00734.2009 · Cited by 221

The Effect of Muscle-Damaging Exercise on Blood and Skeletal Muscle Oxidative Stress

Nikolaidis, M. G., Jamurtas, A. Z., Paschalis, V., Fatouros, I. G., Koutedakis, Y., & Kouretas, D. (2008) · Sports Medicine · doi:10.2165/00007256-200838070-00005 · Cited by 212

Free Radicals in Exhaustive Physical Exercise: Mechanism of Production, and Protection by Antioxidants

Viña, J., Gómez‐Cabrera, M. C., Lloret, A., Marquez, R., Miñana, J. B., Pallardó, F. V., & Sastre, J. (2000) · IUBMB Life · doi:10.1080/713803729 · Cited by 211

The production of reactive oxygen and nitrogen species by skeletal muscle

Jackson, M. J., Pye, D., & Palomero, J. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01102.2006 · Cited by 212

The participation of coenzyme Q in free radical production and antioxidation

Beyer, R. E. (1990) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(90)90154-b · Cited by 209

Formation of hydrogen peroxide and nitric oxide in rat skeletal muscle cells during contractions

Silveira, L. R., Pereira-da-Silva, L., Juel, C., & Hellsten, Y. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(03)00271-5 · Cited by 208

MDA content increases in fast- and slow-twitch skeletal muscle with intensity of exercise in a rat

Alessio, H. M., Goldfarb, A. H., & Cutler, R. G. (1988) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1988.255.6.c874 · Cited by 206

Exercise-Induced Muscle Damage and the Potential Protective Role of Estrogen

Kendall, B., & Eston, R. G. (2002) · Sports Medicine · doi:10.2165/00007256-200232020-00003 · Cited by 206

Nutritional modulation of training-induced skeletal muscle adaptations

Hawley, J. A., Burke, L. M., Phillips, S. M., & Spriet, L. L. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00949.2010 · Cited by 205

Exercise at Old Age: Does It Increase or Alleviate Oxidative Stress?

Ji, L. L. (2001) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2001.tb05653.x · Cited by 214

Exercise activation of muscle peroxisome proliferator-activated receptor-γ coactivator-1α signaling is redox sensitive

Kang, C., OʼMoore, K. M., Dickman, J. R., & Ji, L. L. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.08.007 · Cited by 213

Release of reactive oxygen and nitrogen species from contracting skeletal muscle cells

Pattwell, D. M., McArdle, A., Morgan, J. E., Patridge, T. A., & Jackson, M. J. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.06.026 · Cited by 204

Mechanism of Free Radical Production in Exhaustive Exercise in Humans and Rats; Role of Xanthine Oxidase and Protection by Allopurinol

Viña, J., Gimeno, A., Sastre, J., Desco, C., Asensi, M. A., Pallardó, F. V., Cuesta, A. Z., Ferrero, J. A., Terada, L. S., & Repine, J. E. (2000) · IUBMB Life · doi:10.1080/15216540050167098 · Cited by 203

Diabetes, Oxidative Stress and Physical Exercise

Atalay, M., & Laaksonen, D. E. (2002) · Journal of Sports Science and Medicine · doi:10.52082/jssm.2002.1 · Cited by 203

Free radical generation and oxidative stress with ageing and exercise: Differential effects in the myocardium and liver

Bejma, Ramires, J. A. F., & Ji (2000) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2000.00745.x · Cited by 203

Nitric oxide, reactive oxygen species, and skeletal muscle contraction

Reid, M. B. (2001) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200103000-00006 · Cited by 198

The general case for redox control of wound repair

Sen, C. K. (2003) · Wound Repair and Regeneration · doi:10.1046/j.1524-475x.2003.11607.x · Cited by 197

Redox Control of Skeletal Muscle Regeneration

Moal, E. L., Pialoux, V., Juban, G., Groussard, C., Zouhal, H., Chazaud, B., & Mounier, R. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6782 · Cited by 206

The excitation–contraction coupling mechanism in skeletal muscle

Calderón, J. C., Bolaños, P., & Caputo, C. A. (2014) · Biophysical Reviews · doi:10.1007/s12551-013-0135-x · Cited by 230

Changes in the glutathione status of plasma, liver and muscle following exhaustive exercise in rats

Lew, H., Pyke, S., & Quintanilha, A. T. (1985) · FEBS Letters · doi:10.1016/0014-5793(85)80919-4 · Cited by 196

L-Propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector

Vanella, A., Russo, A., Acquaviva, R., Campisi, A., Giacomo, C. D., Sorrenti, V., & Barcellona, M. L. (2000) · Cell Biology and Toxicology · doi:10.1023/a:1007638025856 · Cited by 194

Apoptosis and exercise

Phaneuf, S., & Leeuwenburgh, C. (2001) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200103000-00010 · Cited by 193

Alteration of Liver Cell Function and Proliferation: Differentiation Between Adaptation and Toxicity

Williams, G. M., & Iatropoulos, M. J. (2002) · Toxicologic Pathology · doi:10.1080/01926230252824699 · Cited by 191

Does Oxidative Stress Alter Quadriceps Endurance in Chronic Obstructive Pulmonary Disease?

Koechlin‐Ramonatxo, C., Couillard, A., Simar, D., Cristol, J., Bellet, H., Hayot, M., & PREFAUT, C. G. (2004) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200310-1465oc · Cited by 197

Exercise increases BDNF levels in the striatum and decreases depressive-like behavior in chronically stressed rats

Marais, L., Stein, D. J., & Daniels, W. M. U. (2009) · Metabolic Brain Disease · doi:10.1007/s11011-009-9157-2 · Cited by 197

Soccer players under regular training show oxidative stress but an improved plasma antioxidant status

Brites, F. D., Evelson, P., CHRISTIANSEN, M. G., NICOL, M. Í. F., BASÍLICO, M. J., Wikinski, R. L. W., & Llesuy, S. (1999) · Clinical Science · doi:10.1042/cs0960381 · Cited by 187

Adaptive Response and Oxidative Stress

Crawford, D. R., & Davies, K. J. A. (1994) · Environmental Health Perspectives · doi:10.1289/ehp.94102s1025 · Cited by 187

Electron spin resonance spectroscopic detection of oxygen-centred radicals in human serum following exhaustive exercise

Ashton, T., Rowlands, C. C., Jones, E., Young, I. S., Jackson, S. K., Davies, B., & Peters, J. R. (1998) · European Journal of Applied Physiology · doi:10.1007/s004210050366 · Cited by 185

Redefining the major contributors to superoxide production in contracting skeletal muscle. The role of NAD(P)H oxidases

Sakellariou, G. K., Jackson, M. J., & Vasilaki, A. (2014) · Free Radical Research · doi:10.3109/10715762.2013.830718 · Cited by 184

Antioxidant signaling in skeletal muscle: A brief review

Ji, L. L. (2007) · Experimental Gerontology · doi:10.1016/j.exger.2007.03.002 · Cited by 196

Intense physical training decreases circulating antioxidants and endothelium-dependent vasodilatation in vivo

Bergholm, R., Mäkimattila, S., Valkonen, M. M., Liu, M., Lahdenperä, S., Taskinen, M., Sovijärvi, A. R. A., Malmberg, L. P., & Yki-Järvinen, H. (1999) · Atherosclerosis · doi:10.1016/s0021-9150(99)00089-1 · Cited by 182

Contractile response to low peroxide concentrations: myofibrillar calcium sensitivity as a likely target for redox‐modulation of skeletal muscle function

Andrade, F. H., Reid, M. B., & Westerblad, H. (2000) · The FASEB Journal · doi:10.1096/fj.00-0507fje · Cited by 181

Changes in skeletal muscle heat shock proteins Pathological significance

Liu, Y. (2001) · Frontiers in bioscience · doi:10.2741/liu · Cited by 180

Oxidative Stress and Aging: Role of Exercise and Its Influences on Antioxidant Systems

Ji, L. L., Leeuwenburgh, C., Leichtweis, S. B., Gore, M., Fiebig, R., Hollander, J. M., & Bejma, J. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb09896.x · Cited by 185

Age‐related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species

Jackson, M. J., & McArdle, A. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.206623 · Cited by 177

The Mitochondrial Free Radical Theory of Aging: A Critical View

Sanz, A., & Stefanatos, R. K. A. (2008) · Current Aging Science · doi:10.2174/1874609810801010010 · Cited by 177

Elevated serum antioxidant capacity and plasma malondialdehyde concentration in response to a simulated half-marathon run

Child, R. B., Wilkinson, D. M., FALLOWFIELD, J. L., & Donnelly, A. (1998) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199811000-00008 · Cited by 177

Oxidative Stress Regulation of Stem and Progenitor Cells

Pervaiz, S., Taneja, R., & Ghaffari, S. (2009) · Antioxidants & Redox Signaling · doi:10.1089/ars.2009.2804 · Cited by 176

HSP72 as a complementary protection against oxidative stress induced by exercise in the soleus muscle of rats

Smolka, M. B., Zoppi, C. C., Alves, A. A., Silveira, L. R., Marangoni, S., Pereira-da-Silva, L., Novello, J. C., & de Macedo, D. V. (2000) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2000.279.5.r1539 · Cited by 176

Vitamin E prevents exercise-induced DNA damage

Hartmann, A., Nieβ, A. M., Grünert-Fuchs, M., Poch, B., & Speit, G. (1995) · Mutation Research Letters · doi:10.1016/0165-7992(95)90035-7 · Cited by 176

Exercise-induced hormesis and skeletal muscle health

Ji, L. L., Kang, C., & Zhang, Y. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.02.025 · Cited by 182

The role of vitamin E in normal and damaged skin

Nachbar, F., & Korting, H. C. (1995) · Journal of Molecular Medicine · doi:10.1007/bf00203614 · Cited by 175

Exercise and skeletal muscle ageing: cellular and molecular mechanisms

McArdle, A., Vasilaki, A., & Jackson, M. J. (2002) · Ageing Research Reviews · doi:10.1016/s0047-6374(01)00368-2 · Cited by 174

The oxidant/antioxidant equilibrium in horses

Kirschvink, N. A., de Moffarts, B., & Lekeux, P. M. (2007) · The Veterinary Journal · doi:10.1016/j.tvjl.2007.07.033 · Cited by 174

Age‐associated increases in oxidative stress and nuclear transcription factor κB activation are attenuated in rat liver by regular exercise

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