Cited by 247Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychotherapy Techniques and Applications

The DOI matches its Crossref record; 43 of the 44 references it cites were found in a registry or an index.

Major depressive subtypes and treatment response

Fava, Maurizio, Uebelacker, Lisa A., Alpert, Jonathan E., Nierenberg, Andrew A., Pava, Joel A., Rosenbaum, Jerrold F.·1997·Biological Psychiatry

DOI 10.1016/s0006-3223(96)00440-4

Open this paper in CoChat — free account

Abstract

The purpose of this study was to investigate the relationships between depressive subtypes and response to fluoxetine treatment in a large cohort of outpatients. We studied 294 outpatients with major depressive disorder who were then treated with fluoxetine 20 mg/day for 8 weeks. Treatment outcome was evaluated with the Hamilton Depression Rating Scale (HDRS)-17, the Clinical Global Impressions-Severity, and with the HDRS-8; the latter is proposed to be a relatively more specific measure of depression severity than the HDRS-17. We assessed the relationships between degree of treatment response and several depressive subtypes (melancholic, atypical, hostile, and anxious depression, double depression, and depression with comorbid personality disorders), after adjusting for baseline depression severity. We found that nonanxious depressives (patients without any comorbid anxiety disorder) improved slightly but significantly more during treatment than anxious depressives on all outcome measures. Melancholic depression was associated with slightly less improvement on the HDRS-17 only, whereas the other subtypes of depression were not associated with differences in treatment outcome.

Integrity signals

Registry

Crossref · 10.1016/s0006-3223(96)00440-4

Cites

43 of 43 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A rating scale for depression
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Untitled work
(1976) · Medical Entomology and Zoology · Cited by 8,899
The Structured Clinical Interview for DSM-III-R (SCID): I: History, Rationale, and Description
Spitzer, R. L. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820080032005 · Cited by 4,336
Structured Clinical Interview for DSM-III-R Personality Disorders
First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (2012) · PsycTESTS Dataset · doi:10.1037/t07827-000 · Cited by 1,403
"Double depression": superimposition of acute depressive episodes on chronic depressive disorders
Keller, M. B., & Shapiro, R. W. (1982) · American Journal of Psychiatry · doi:10.1176/ajp.139.4.438 · Cited by 364
Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia
Roose, S. P., Glassman, A. H., Attia, E., & Woodring, S. (1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.12.1735 · Cited by 286
148th Annual Meeting of the American Psychiatric Association
Dittmann, V., Krausz, M. R., Haasen, C., Mass, R., Wagner, H.-B., Peter, H., Freyberger, H. J., Wïttchen, H., Perkonigg, A., Krausz, M. R., et al. (2010) · European Addiction Research · doi:10.1159/000319611 · Cited by 259
Comorbidity of personality disorders and depression: Implications for treatment.
Shea, M. T., Widiger, T. A., & Klein, M. H. (1992) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.60.6.857 · Cited by 255
Melancholic symptom features and DSM-IV
Rush, A. J., & Weissenburger, J. (1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.4.489 · Cited by 254
"Double depression": two-year follow-up
Keller, M. B., Lavori, P. W., Endicott, J., Coryell, W. H., & Klerman, G. L. (1983) · American Journal of Psychiatry · doi:10.1176/ajp.140.6.689 · Cited by 250

Show all 44 references

Research works printed but not linked: 1

Fava, 1991, Anger attacks in depressed outpatients, Psychopharmacol Bull, 27, 275

Sorted by citations

Items 101–200 of 244

Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis
Li, D., Pain, O., Fabbri, C., Wong, W. L. E., Lo, C. W. H., Ripke, S., Cattaneo, A., Souery, D., Dernovšek, M. Z., Henigsberg, N., et al. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02981-1 · Cited by 40
EEG Hemispheric Asymmetries during Cognitive Tasks in Depressed Patients with High versus Low Trait Anxiety
Manna, C. B. G., Tenke, C. E., Gates, N. A., Jürgen Kayser, A., Borod, J. C., Stewart, J. W., McGrath, P. J., & Bruder, G. E. (2010) · Clinical EEG and Neuroscience · doi:10.1177/155005941004100406 · Cited by 37
A quantitative review on outcome-to-antidepressants in melancholic unipolar depression
Valerio, M. P., Szmulewicz, A., & Martino, D. J. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.03.088 · Cited by 37
Machine learning, pharmacogenomics, and clinical psychiatry: predicting antidepressant response in patients with major depressive disorder
Bobo, W. V., Ommeren, B. V., & Athreya, A. P. (2022) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2022.2112949 · Cited by 39
Diurnal mood variation in outpatients with major depressive disorder
Morris, D. W., Trivedi, M. H., D, M. F. M., Wisniewski, S. R., Balasubramani, G. K., Khan, A. Y., Jain, S. B., & Rush, A. J. (2009) · Depression and Anxiety · doi:10.1002/da.20557 · Cited by 38
Anxious Depression and Response to Treatment
Nelson, J. C. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07121927 · Cited by 35
Electroencephalogram patterns in patients comorbid with major depressive disorder and anxiety symptoms: Proposing a hypothesis based on hypercortical arousal and not frontal or parietal alpha asymmetry
Lin, I., Chen, T., Lin, H., Wang, S.-Y., Sung, J.-L., & Yen, C. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.01.001 · Cited by 35
Association of Baseline Anxiety With Depression Persistence at 6 Months in Patients With Acute Cardiac Illness
Celano, C. M., Mastromauro, C. A., Lenihan, E. C., Januzzi, J. L., Rollman, B. L., & Huffman, J. C. (2011) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31823d38bc · Cited by 36
Prevalence, structure and correlates of anxiety-depression in boys with an autism spectrum disorder
Bitsika, V., Sharpley, C. F., Andronicos, N. M., & Agnew, L. L. (2016) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2015.11.011 · Cited by 37
Anger Attacks in Depressed Turkish Outpatients
Sayar, K., Güzelhan, Y., Solmaz, M., Özer, Ö. A., Öztürk, M., Acar, B., & Arikan, M. (2000) · Annals of Clinical Psychiatry · doi:10.1023/a:1009082409702 · Cited by 34
Relationships between major depressive disorder and comorbid anxiety and personality disorders
Farabaugh, A. H., D, M. F. M., Mischoulon, D., Sklarsky, K., Petersen, T., & Alpert, J. E. (2005) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2004.10.005 · Cited by 34
Self-citation
The predictive power of subgroups: An empirical approach to identify depressive symptom patterns that predict response to treatment
Bühler, J., Seemüller, F., & Läge, D. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.03.053 · Cited by 35
Depression and anxiety in supportive oncology
Li, M., Boquiren, V., Lo, C., & Rodin, G. (2011) · Supportive Oncology · doi:10.1016/b978-1-4377-1015-1.00052-7 · Cited by 32
Baseline mood-state measures as predictors of antidepressant response to scopolamine
Furey, M. L., Nugent, A. C., Speer, A. M., Luckenbaugh, D. A., Hoffman, E. M., Frankel, E., Drevets, W. C., & Zarate, C. A. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2012.01.003 · Cited by 32
Effects of tandospirone augmentation in major depressive disorder patients with high anxiety: A multicenter, randomized, parallel-controlled, open-label study
Lin, J., Su, Y., Wang, C., Yang, F., Xu, Y., Yuan, Y., Yuan, Y., Wang, X., Yu, X., & Si, T. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.01.020 · Cited by 32
Prospective evaluation of specialist inpatient treatment for refractory affective disorders
Wooderson, S. C., Juruena, M. F., Fekadu, A., Commane, C., Donaldson, C., Cowan, M., Tomlinson, M., Poon, L., Markopoulou, K., Rane, L. J., et al. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.11.002 · Cited by 31
Clinical and sociodemographic predictors of response to augmentation, or dose increase among depressed outpatients resistant to fluoxetine 20 mg/day
Perlis, R. H., Alpert, J. E., Nierenberg, A. A., Mischoulon, D., Yeung, A., Rosenbaum, J. F., & D, M. F. M. (2003) · Acta Psychiatrica Scandinavica · doi:10.1046/j.0001-690x.2003.00168.x · Cited by 31
Self-citation
Selective serotonin reuptake inhibitor efficacy in severe and melancholic depression
Amsterdam, J. D. (1998) · Journal of Psychopharmacology · doi:10.1177/0269881198012003061 · Cited by 32
Correlates and outcomes of depressed out-patients with greater and fewer anxious symptoms: a CO-MED report
Chan, H. N., Rush, A. J., Nierenberg, A. A., Trivedi, M., Wisniewski, S. R., Balasubramani, G. K., Friedman, E. S., Gaynes, B. N., Davis, L., Morris, D., et al. (2012) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145711001660 · Cited by 30
Self-citation
Algorithms For Treatment of Major Depressive Disorder: Efficacy and Cost-Effectiveness
Bauer, M., Rush, A. J., Ricken, R., Pilhatsch, M., & Adli, M. (2018) · Pharmacopsychiatry · doi:10.1055/a-0643-4830 · Cited by 32
Impaired fear learning and extinction, but not generalization, in anxious and non-anxious depression
Wurst, C., Schiele, M. A., Stonawski, S., Weiß, C., Nitschke, F., Hommers, L. G., Domschke, K., Herrmann, M. J., Pauli, P., Deckert, J., et al. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.01.034 · Cited by 30
Surrogate markers of treatment outcome in major depressive disorder
Papakostas, G. I. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145711001246 · Cited by 29
Generalized anxiety disorder within the course of major depressive disorder: examining the utility of the DSM‐IV hierarchy rule
Lawrence, A. E., Liverant, G. I., Rosellini, A. J., & Brown, T. A. (2009) · Depression and Anxiety · doi:10.1002/da.20607 · Cited by 28
Emerging treatments for depression
Holtzheimer, P. E., & Nemeroff, C. B. (2006) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.7.17.2323 · Cited by 27
Effect of Medical Comorbidity on Response to Fluoxetine Augmentation or Dose Increase in Outpatients With Treatment-Resistant Depression
Perlis, R. H., Iosifescu, D. V., Alpert, J. E., Nierenberg, A. A., Rosenbaum, J. F., & D, M. F. M. (2004) · Psychosomatics · doi:10.1176/appi.psy.45.3.224 · Cited by 27
Self-citation
Personality traits as predictors of depression across the lifespan
Yang, Z., Li, A., Roske, C., Alexander, N., & Gabbay, V. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.03.073 · Cited by 27
The Efficacy and Tolerability of Duloxetine in the Treatment of Anxious Versus Non-Anxious Depression: A Post-Hoc Analysis of an Open-Label Outpatient Study
Fava, M., Martinez, J. M., Greist, J., Marangell, L. B., Brown, E., Chen, L., & Wohlreich, M. M. (2007) · Annals of Clinical Psychiatry · doi:10.1080/10401230701465178 · Cited by 25
What Is the Best Sequential Treatment Strategy in the Treatment of Depression? Adding Pharmacotherapy to Psychotherapy or Vice Versa?
Dekker, J., Van, H. L., Hendriksen, M., Koelen, J. A., Schoevers, R. A., Kool, S., van Aalst, G., & Peen, J. (2012) · Psychotherapy and Psychosomatics · doi:10.1159/000341177 · Cited by 26
Behavioral Activation for the Treatment of Atypical Depression: A Pilot Open Trial
Weinstock, L. M., Munroe, C., & Miller, I. W. (2011) · Behavior Modification · doi:10.1177/0145445511405646 · Cited by 25
Determinants of Treatment-Resistant Depression
Parker, G. B., & Graham, R. (2015) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000348 · Cited by 25
Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models
Hughes, M. C., Pradier, M. F., Ross, A. S., McCoy, T. H., Perlis, R. H., & Doshi‐Velez, F. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.5308 · Cited by 25
Fluoxetine-clonazepam cotherapy for anxious depression: an exploratory, post-hoc analysis of a randomized, double blind study
Papakostas, G. I., Clain, A. J., Ameral, V., Baer, L., Brintz, C., Smith, W. T., Londborg, P. D., Glaudin, V., Painter, J. R., & D, M. F. M. (2009) · International Clinical Psychopharmacology · doi:10.1097/yic.0b013e32833205a4 · Cited by 24
A preliminary assessment of a combination of rhodiola and saffron in the management of mild–moderate depression
Bangratz, M., Abdellah, S. A., Berlin, A., Blondeau, C., Guilbot, A., Dubourdeaux, M., & Lemoine, P. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s169575 · Cited by 24
Variability in Anxiety and Depression Over Time Following Diagnosis in Patients with Prostate Cancer
Sharpley, C. F., Christie, D., & Bitsika, V. (2010) · Journal of Psychosocial Oncology · doi:10.1080/07347332.2010.516810 · Cited by 24
Biological Markers of Atypical Depression
Posternak, M. A. (2003) · Harvard Review of Psychiatry · doi:10.1080/10673220303941 · Cited by 24
Clinical Characteristics Associated With Treatment-Resistant Bipolar Disorder
Parker, G. B., & Graham, R. (2016) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000517 · Cited by 23
Perceived Stress and Cognitive Vulnerability Mediate the Effects of Personality Disorder Comorbidity on Treatment Outcome in Major Depressive Disorder
Candrian, M., Farabaugh, A. H., Pizzagalli, D. A., Baer, L., & D, M. F. M. (2007) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0b013e318142cbd5 · Cited by 23
Lurasidone for major depressive disorder with mixed features and anxiety: a post-hoc analysis of a randomized, placebo-controlled study
Tsai, J., Thase, M. E., Mao, Y., Ng-Mak, D., Pikalov, A., & Loebel, A. (2017) · CNS Spectrums · doi:10.1017/s1092852917000074 · Cited by 22
Personality classification enhances blood metabolome analysis and biotyping for major depressive disorders: two-species investigation
Setoyama, D., Yoshino, A., Takamura, M., Okada, G., Iwata, M., Tsunetomi, K., Ohgidani, M., Kuwano, N., Yoshimoto, J., Okamoto, Y., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.09.118 · Cited by 23
Do hormone treatments for prostate cancer cause anxiety and depression?
Sharpley, C. F., Christie, D., & Bitsika, V. (2013) · International Journal of Clinical Oncology · doi:10.1007/s10147-013-0569-y · Cited by 22
Fluoxetine treatment of depressed patients with comorbid anxiety disorders
Sonawalla, S. B., Farabaugh, A. H., Johnson, M. W., Morray, M., Delgado, M. L., Pingol, M. G., Rosenbaum, J. F., & D, M. F. M. (2002) · Journal of Psychopharmacology · doi:10.1177/026988110201600304 · Cited by 22
Self-citation
Melancholia and axis II comorbidity
Tedlow, J. R., Smith, M. M., Neault, N. B., Polania, L. M., Alpert, J. E., Nierenberg, A. A., & D, M. F. M. (2002) · Comprehensive Psychiatry · doi:10.1053/comp.2002.34631 · Cited by 22
Self-citation
Individual Deviations from Normative Electroencephalographic Connectivity Predict Antidepressant Response
Tong, X., Xie, H., Wu, W., Keller, C. J., Fonzo, G. A., Chidharom, M., Carlisle, N. B., Etkin, A., & Zhang, Y. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.01.177 · Cited by 22
IRRITABLE MOOD IN ADULT MAJOR DEPRESSIVE DISORDER: RESULTS FROM THE WORLD MENTAL HEALTH SURVEYS
Kovess–Masféty, V., Alonso, J., Angermeyer, M. C., Bromet, E. J., de Girolamo, G., de Jonge, P., Demyttenaere, K., Florescu, S., Gruber, M. J., Gureje, O., et al. (2013) · Depression and Anxiety · doi:10.1002/da.22033 · Cited by 21
Genome-wide association study of co-occurring anxiety in major depression
Schosser, A., Butler, A. W., Uher, R., Ng, M., Cohen‐Woods, S., Craddock, N. J., Owen, M., Korszun, A., Gill, M., Rice, J. P., et al. (2013) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2013.782107 · Cited by 21
The Role of Anger/Hostility in Treatment-Resistant Depression
Fisher, L. B., D, M. F. M., Doros, G. D., Alpert, J. E., Henry, M. W., Huz, I., & Freeman, M. P. (2015) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000364 · Cited by 22
Self-citation
Stability of symptoms across major depressive episodes in bipolar disorder
Perlis, R. H., Ostacher, M. J., Uher, R., Nierenberg, A. A., Casamassima, F., Kansky, C., Calabrese, J. R., Thase, M. E., & Sachs, G. S. (2009) · Bipolar Disorders · doi:10.1111/j.1399-5618.2009.00764.x · Cited by 23
Self-citation
Antidepressant Response and Well-Being in Pre-, Peri- and Postmenopausal Women with Major Depressive Disorder Treated with Fluoxetine
Cassano, P., Soares, C. N., Cusin, C., Mascarini, A., Cohen, L. S., & D, M. F. M. (2005) · Psychotherapy and Psychosomatics · doi:10.1159/000087783 · Cited by 21
Assessing anxious features in depressed outpatients
McClintock, S. M., Husain, M. M., Bernstein, I. H., Wisniewski, S. R., Trivedi, M. H., Morris, D. W., Alpert, J. E., Warden, D., Luther, J. F., Kornstein, S. G., et al. (2011) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.353 · Cited by 20
Self-citation
The Roles of Exercise and Yoga in Ameliorating Depression as a Risk Factor for Cognitive Decline
Mathersul, D. C., & Rosenbaum, S. (2016) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2016/4612953 · Cited by 20
Behavioral and Emotional Disturbances in the Offspring of Depressed Parents with Anger Attacks
Alpert, J. E., Petersen, T., Roffi, P. A., Papakostas, G. I., Freed, R. D., Smith, M. M., Spector, A. R., Nierenberg, A. A., Rosenbaum, J. F., & D, M. F. M. (2003) · Psychotherapy and Psychosomatics · doi:10.1159/000068682 · Cited by 20
Self-citation
Raising the Minimum Effective Dose of Serotonin Reuptake Inhibitor Antidepressants: Adverse Drug Events
Safer, D. J. (2016) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000000564 · Cited by 19
Sex- and age-related differences in major depressive disorder with comorbid anxiety treated with fluoxetine
Cassano, P., Soares, C. N., Cohen, L. S., Lyster, A. K., & D, M. F. M. (2004) · Archives of Women s Mental Health · doi:10.1007/s00737-004-0051-y · Cited by 19
Identifying Patients at Risk of Complete Nonresponse in the Outpatient Treatment of Depression
Van, H. L., Dekker, J., Peen, J., van Aalst, G., & Schoevers, R. A. (2008) · Psychotherapy and Psychosomatics · doi:10.1159/000151389 · Cited by 18
Differences in major depressive disorder and generalised anxiety disorder symptomatology between prostate cancer patients receiving hormone therapy and those who are not
Sharpley, C. F., Bitsika, V., Wootten, A. C., & Christie, D. (2014) · Psycho-Oncology · doi:10.1002/pon.3566 · Cited by 17
Is there a relationship between depression with anxious distress DSM-5 specifier and bipolarity? A multicenter cohort study on patients with unipolar, bipolar I and II disorders
Tundo, A., Musetti, L., de Filippis, R., Grande, C. D., Falaschi, V., Proietti, L., & Dell’Osso, L. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.11.024 · Cited by 17
Are SSRIs Really More Effective for Anxious Depression?
Panzer, M. J. (2005) · Annals of Clinical Psychiatry · doi:10.1080/10401230590905317 · Cited by 17
Resistance to antidepressant treatment among patients with major depressive disorder: a nationwide study
Chen, L.-C., Chen, M., Bai, Y., Chen, T.-J., & Su, T. (2024) · International Clinical Psychopharmacology · doi:10.1097/yic.0000000000000574 · Cited by 18
Incidence and nature of anxiety–depression comorbidity in prostate cancer patients
Sharpley, C. F., Bitsika, V., & Christie, D. (2010) · Journal of Men s Health · doi:10.1016/j.jomh.2010.03.003 · Cited by 16
Screening for anxiety disorders in depressed patients
Zimmerman, M. A., & Chelminski, I. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2005.03.001 · Cited by 16
Treatment of depression with comorbid anxiety disorders: differential efficacy of paroxetine versus moclobemide
Pini, S., AMADOR, X. F., Osso, L. D., Rossi, N. B., Cassano, P., Savino, M., & Cassano, G. B. (2003) · International Clinical Psychopharmacology · doi:10.1097/00004850-200301000-00003 · Cited by 16
Does the presence of accompanying symptom clusters differentiate the comparative effectiveness of second-line medication strategies for treating depression?
Gaynes, B. N., Farley, J. F., Dusetzina, S. B., Ellis, A. R., Hansen, R. A., Miller, W. C., & Stürmer‎, T. (2011) · Depression and Anxiety · doi:10.1002/da.20898 · Cited by 15
Does comorbid subthreshold anxiety predict treatment response in depression? Results from a naturalistic cohort study (the CRESCEND study)
Seo, H.-J., Song, H. R., Jeong, S., Kim, J.-B., Lee, M.-S., Kim, J.-M., Yim, H. W., & Jun, T.-Y. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.09.037 · Cited by 13
Effects of Anxious Depression on Antidepressant Treatment Response
Hampf, C., Scherf‐Clavel, M., Weiß, C., Klüpfel, C., Stonawski, S., Hommers, L. G., Lichter, K., Erhardt, A., Unterecker, S., Domschke, K., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417128 · Cited by 13
Mental Health of Cross-Cultural Healthcare Missionaries
Strand, M. A., Pinkston, L. M., Chen, A. I., & Richardson, J. W. (2015) · Journal of Psychology and Theology · doi:10.1177/009164711504300406 · Cited by 13
Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures
Harris, M. A., Shen, X., Cox, S. R., Gibson, J., Adams, M. J., Clarke, T., Deary, I. J., Lawrie, S. M., McIntosh, A. M., & Whalley, H. C. (2019) · Psychological Medicine · doi:10.1017/s003329171900165x · Cited by 13
Mental Health Resource Utilization and Health Care Costs Associated With Race and Comorbid Anxiety Among Medicaid Enrollees with Major Depressive Disorder
Wu, C., Erickson, S. R., Piette, J. D., & Balkrishnan, R. (2012) · Journal of the National Medical Association · doi:10.1016/s0027-9684(15)30121-8 · Cited by 12
The Next Big Thing in Child and Adolescent Psychiatry
Shoemaker, E. Z., Tully, L. M., Niendam, T. A., & Peterson, B. S. (2015) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2015.05.010 · Cited by 12
Is there a place for tricyclic antidepressants and subsequent augmentation strategies in obtaining remission for patients with treatment resistant depression?
Gervasoni, N., Aubry, J., Gex‐Fabry, M., Bertschy, G., & Bondolfi, G. (2008) · Pharmacological Research · doi:10.1016/j.phrs.2008.11.005 · Cited by 12
Treating each and every depressed patient
Kennedy, S. H. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881108093270 · Cited by 12
Anxious depression among the elderly: Clinical and phenomenological correlates
Lynch, T. R., Compton, J. S., Mendelson, T., Robins, C. J., & Krishnan, K. (2000) · Aging & Mental Health · doi:10.1080/713649922 · Cited by 11
Monoaminergic‐based Pharmacotherapy for Depression
Papakostas, G. I., & D, M. F. M. (2005) · Wiley eBooks · doi:10.1002/9783527619672.ch6 · Cited by 11
Serotonin and the prediction of response time to fluoxetine in patients with mild depression
New, A. S., Woo-Ming, A. M., Mitropoulou, V., Silverman, J. M., Reynolds, D. A., Schopick, F., Trestman, R. L., & Siever, L. J. (1999) · Psychiatry Research · doi:10.1016/s0165-1781(99)00057-8 · Cited by 11
Assessment and treatment of depression associated with dementia
Hughes, L. D., Murphy, F., & Findlay, D. J. (2019) · British Journal of Hospital Medicine · doi:10.12968/hmed.2019.80.3.151 · Cited by 10
Predictors of the effectiveness of an early medication change strategy in patients with major depressive disorder
Dreimüller, N., Wagner, S., Engel, A., Braus, D. F., Roll, S. C., Elsner, S., Tadić, A., & Lieb, K. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2014-x · Cited by 10
Anxiety Symptom Severity and Long‐term Risk for Suicidal Behavior in Depressive Disorders
Coryell, W. H., Fiedorowicz, J. G., Solomon, D., Endicott, J., & Keller, M. B. (2019) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.12555 · Cited by 9
Mixed, Melancholic, and Anxious Features in Depression: A Cross-Sectional Study of Sociodemographic and Clinical Correlates
Zaninotto, L., Souery, D., Calati, R., Scudellari, P., Janiri, L., Montgomery, S., Kasper, S. F., Zohar, J., Mendlewicz, J., & Serretti, A. (2014) · Annals of Clinical Psychiatry · doi:10.1177/104012371402600402 · Cited by 8
The effects of aripiprazole on the subscales of the Kellner Symptom Questionnaire in treatment resistant depression
Dording, C. M., Cassiello-Robbins, C. F., King, F., Pencina, M. J., D, M. F. M., & Mischoulon, D. (2013) · International Clinical Psychopharmacology · doi:10.1097/yic.0b013e32836220df · Cited by 8
Sublingually Administered Fluoxetine for Major Depression in Medically Compromised Patients
Pakyürek, M., & Pasol, E. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.11.1833-a · Cited by 8
Perspectives on the success rate of current antidepressant pharmacotherapy
Goldberg, J. F. (2022) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2022.2138333 · Cited by 6
The effects of levomilnacipran ER in adult patients with first-episode, highly recurrent, or chronic MDD
Kornstein, S. G., Gommoll, C., Chen, C., & Kramer, K. L. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.12.058 · Cited by 6
Deep brain stimulation improves symptoms across all dimensions in treatment-resistant depression
Runia, N., Mol, G. J. J., Denys, D. A. J. P., Ardon, H., Beute, G. N., Bot, M., de Waardt, D. A., de Knijff, D. W. W., Mocking, R. J. T., Notten, P., et al. (2025) · Neurotherapeutics · doi:10.1016/j.neurot.2025.e00623 · Cited by 5
Antidepressant and antianxiety properties of saffron
Mohajeri, S. A., Sepahi, S., & Ghorani‐Azam, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818638-1.00028-9 · Cited by 6
Co-occurring anxiety and depression: concepts, significance, and treatment implications
McGrath, P. J., & Miller, J. M. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511777578.011 · Cited by 5
The Association Between the Sedative Loads and Clinical Severity Indicators in the First-Onset Major Depressive Disorder
Wang, Y.-C., Lin, H.-T., Lu, M., Huang, M., Chen, C.-H., Wu, T., Wang, S. Z., Mao, W., Kuo, P., & Chen, H. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00129 · Cited by 5
Personalized Medicine
Foster, S. L., Petrie, S. R., Mischoulon, D., & D, M. F. M. (2018) · Springer eBooks · doi:10.1007/978-3-319-97241-1_8 · Cited by 6
Particularités médicosociales de la dépression du sujet âgé : le point en 2008
Thomas, P., & Hazif‐Thomas, C. (2008) · NPG. Neurologie, psychiatrie, gériatrie/NPG · doi:10.1016/j.npg.2008.02.001 · Cited by 5
RETRACTED–Effect of ketamine on anxiety: findings from the Ketamine for Adult Depression Study
Mills, N. T., Nikolin, S., Glozier, N., Barton, D., Baune, B. T., Fitzgerald, P. B., Glue, P., Sarma, S., Rodgers, A., Hadzi-Pavlovic, D., et al. (2025) · The British Journal of Psychiatry · doi:10.1192/bjp.2024.250 · Cited by 4
Retracted
Komorbide Störungen
Gouzoulis‐Mayfrank, E., Schweiger, U., & Sipos, V. (2008) · Elsevier eBooks · doi:10.1016/b978-343723730-0.50034-3 · Cited by 4
Depression and Anxiety Emerging From Heavy Metals
Lahouaoui, H., Aimrane, A., Khamsi, Y., Zouhairi, N., Benammi, H., Hidan, M. A. E., Draoui, A., Alahyane, H., & Bouazza, A. (2019) · Advances in environmental engineering and green technologies book series · doi:10.4018/978-1-5225-7775-1.ch015 · Cited by 4
Definición e impacto de las depresiones resistentes/refractarias al tratamiento
Tamayo, J. M., Rosales-Barrera, J. I., Villaseñor-Bayardo, S. J., & Rojas-Malpica, C. (2011) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 4
A preliminary open study of the tolerability and effectiveness of nefazodone in major depressive disorder: Comparing patients who recently discontinued an ssri with those on no recent antidepressant treatment
Mischoulon, D., OPITZ, G. M., Kelly, K. E., D, M. F. M., & Rosenbaum, J. F. (2004) · Depression and Anxiety · doi:10.1002/da.10127 · Cited by 4
Self-citation
Beyond total depressive symptoms: Differential associations between depressive domains, HIV status and disease characteristics
Prescott, M., Wang, C., Gentry, M. M., Franklin, D., Stein, M. B., Atkinson, J. H., Ellis, R. J., Heaton, R. K., Montoya, J. L., Moore, D. J., et al. (2025) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2025.112311 · Cited by 3
Personalised transcranial magnetic stimulation for treatment-resistant depression, depression with comorbid anxiety and negative symptoms of schizophrenia: a narrative review
Tan, X. W., Singh, H. K. G., Koh, J. Z. J., Tan, R. S. Y., & Tor, P. C. (2024) · Singapore Medical Journal · doi:10.4103/singaporemedj.smj-2024-133 · Cited by 3
A quick behavioral dichotic word test is prognostic for clinical response to cognitive therapy for depression: A replication study
Bruder, G. E., Haggerty, A. E., & Siegle, G. J. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.12.011 · Cited by 3
Diagnosis, classification, and differential diagnosis of the mood disorders
Parker, G. B. (2012) · doi:10.1093/med/9780199696758.003.0085 · Cited by 3
Defining and Differentiating Treatment-Resistant Depression
Treviño, K. (2012) · Cited by 3
Correction: Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis
Li, D., Pain, O., Fabbri, C., Wong, W. L. E., Lo, C. W. H., Ripke, S., Cattaneo, A., Souery, D., Dernovšek, M. Z., Henigsberg, N., et al. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03064-x · Cited by 3
Similarities and differences of regional brain activity between first-episode drug-naïve anxious and nonanxious MDD patients
Liu, G., Sun, Z., Zhou, C., Wang, X., Dai, M., Zhang, J., Zhang, R., Xu, H., & Zhang, G. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-07513-9 · Cited by 2
Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms
Ahn, I., Chang, S., Lee, J., Choi, S. H., Han, J., & Kim, Y. (2025) · Advanced Science · doi:10.1002/advs.202508383 · Cited by 2

Authors: Fava, M., Uebelacker, L. A., Alpert, J. E., Nierenberg, A. A., Pava, J. A., & Rosenbaum, J. F.
Affiliations: Massachusetts General Hospital (US)
ORCID: Uebelacker, Lisa A.
Alpert, Jonathan E.
Nierenberg, Andrew A.
Venue: Biological Psychiatry
Publisher: Elsevier BV
Published: 1997-10
Volume: 42
Issue: 7
Pages: 568-576
ISSN: 0006-3223 (ISSN-L)
DOI: 10.1016/s0006-3223(96)00440-4
OpenAlex: W1972105422
Cited by: 247
References: 44
Citations by year: 2026: 2 · 2025: 7 · 2024: 9 · 2023: 5 · 2022: 5 · 2021: 4 · 2020: 5 · 2019: 7 · 2018: 9 · 2017: 8 · 2016: 9 · 2015: 10 · 2014: 8 · 2013: 10 · 2012: 11
FWCI: 3.35
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Biological Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (1r01mh048483-01a1)
National Institute of Mental Health (R01 MH48483-01)
Topics: Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords: major depressive disorder, depression subtypes, fluoxetine, treatment response, endogenous depression, atypical depression, anxious depression, double depression, comorbid personality disorders, comorbid anxiety disorders, depression severity, outpatients
MeSH terms: Adolescent, Adult, Aged, Anxiety, Depressive Disorder, Female, Fluoxetine, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Antidepressive Agents, Second-Generation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Major depressive subtypes and treatment response

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks