Cited by 101Neuroscience and Neuropharmacology ResearchMemory and Neural MechanismsNeural dynamics and brain function

Morphological evidence that CA1 hippocampal afferents monosynaptically innervate PV-containing neurons and NADPH-diaphorase reactive cells in the medial prefrontal cortex (Areas 25/32) of the rat

Gabbott, Paul, Headlam, Anthony, Busby, Sarah·2002·Brain Research

Abstract

Immunocytochemical and ultrastructural evidence is presented indicating that direct inputs from the hippocampal CA1 field to prelimbic (area 32) and infralimbic (area 25) cortices in the rat, innervate not only 'spiny' (presumed pyramidal) neurons but also monosynaptically contact NADPH-diaphorase reactive cells and parvalbumin-containing local circuit neurons-the latter cell type is shown to be GABA immunoreactive. Similar evidence of direct CA1 input to local circuit neurons containing either calbindin or calretinin was not found.

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Crossref · 10.1016/s0006-8993(02)02487-3

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Authors
Gabbott, P., Headlam, A., & Busby, S.
Affiliations
University of Oxford (GB)
Corresponding author
Gabbott, Paul
Venue
Brain Research
Publisher
Elsevier BV
Published
2002-08
Volume
946
Issue
2
Pages
314-322
ISSN
0006-8993 (ISSN-L)
OpenAlex
W2111161101
Cited by
101
References
43
Citations by year
2026: 1 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 5 · 2020: 8 · 2019: 5 · 2018: 7 · 2017: 6 · 2016: 7 · 2015: 2 · 2014: 8 · 2013: 6 · 2012: 4
FWCI
1.39
Type
journal article
Language
en
Open access
closed
Locations
  • Brain Research (publishedVersion)
  • PubMed (publishedVersion)
  • Open Research Online (The Open University) (submittedVersion)
Funders
  • Wellcome Trust
  • Royal Society
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords
hippocampal CA1, medial prefrontal cortex, parvalbumin, NADPH-diaphorase, local circuit neurons, GABA immunoreactivity, calbindin, calretinin, pyramidal neurons
MeSH terms
Afferent Pathways, Animals, Electrophysiology, gamma-Aminobutyric Acid, Hippocampus, Immunohistochemistry, Limbic System, Male, NADPH Dehydrogenase, Neurons, Afferent, Parvalbumins, Synapses, Rats, Sprague-Dawley, Prefrontal Cortex, Rats, Calbindins, S100 Calcium Binding Protein G, Calbindin 2

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