Influence of the hippocampus on interneurons of the rat prefrontal cortex
Abstract
The hippocampus and prefrontal cortex (PFC), two structures implicated in learning and memory processes, are linked by a direct hippocampo-prefrontal pathway. It has been shown that PFC pyramidal cells receive monosynaptic excitatory inputs from the hippocampus and, in this study, we sought to determine the influence of the hippocampus on PFC interneurons in anesthetized rats. Extracellular recordings were coupled to juxtacellular injections of neurobiotin or biotinylated dextran amine to morphologically differentiate interneurons from pyramidal cells. In all cases, the action potentials of labeled interneurons were of shorter duration (< 0.70 ms) than those of identified pyramidal cells (> 0.70 ms). Single pulse stimulation of the hippocampal CA1/subiculum region induced an excitatory response in 70% of recorded interneurons in the prelimbic and medial-orbital areas of the PFC. In contrast to the one to two action potentials generated by pyramidal cells, an important group of interneurons fired a burst of action potentials in response to hippocampal stimulation. A large proportion of these excitatory responses was probably monosynaptic as their latency is consistent with the conduction time of the hippocampo-prefrontal pathway. In addition, when both a pyramidal cell and an interneuron were simultaneously recorded and both responded to stimulation, the interneuron consistently fired before the pyramidal cell. In conclusion, the hippocampus exerts a direct excitatory influence on PFC interneurons and is thus capable of feedforward inhibition of pyramidal cells. Hippocampal output is spatially and temporally focalized via this inhibitory process and consequently could facilitate the synchronization of a specific subset of PFC neurons with hippocampal activity.
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The hippocampus-mPFC pathway makes synaptic contact both with glutamatergic pyramidal neurons and GABAergic interneurons within the mPFC.
“This hippocampus-mPFC pathway makes synaptic contact both with glutamatergic pyramidal neurons and GABAergic interneurons within the mPFC”
From The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties (2020) · cites this paper as Tierney et al., 2004
Cites
Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.
Squire, L. R. (1992) · Psychological Review · doi:10.1037/0033-295x.99.2.195 · Cited by 5,376 · see citing works
Ledent, C. A., Valverde, O., Cossu, G., Petitet, F., Aubert, J.-F., Beslot, F., Böhme, G. A., Impérato, A., Pedrazzini, T., Roques, B. P., et al. (1999) · Science · doi:10.1126/science.283.5400.401 · Cited by 3,612 · see citing works
Cellular basis of working memory
Goldman-Rakic, P. S. (1995) · Neuron · doi:10.1016/0896-6273(95)90304-6 · Cited by 2,663 · see citing works
The human hippocampus and spatial and episodic memory
Burgess, N., Maguire, E. A., & O'Keefe, J. (2002) · Neuron · doi:10.1016/s0896-6273(02)00830-9 · Cited by 2,401 · see citing works
Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia
Weinberger, D. R. (1986) · Archives of General Psychiatry · doi:10.1001/archpsyc.1986.01800020020004 · Cited by 2,019 · see citing works
Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex
McCormick, D. A., Connors, B. W., Lighthall, J. W., & Prince, D. A. (1985) · Journal of Neurophysiology · doi:10.1152/jn.1985.54.4.782 · Cited by 1,935 · see citing works
Cholinergic and inhibitory synapses in a pathway from motor‐axon collaterals to motoneurones
Eccles, J. C., Fatt, P., & KOKETSU, K. (1954) · The Journal of Physiology · doi:10.1113/jphysiol.1954.sp005226 · Cited by 1,198 · see citing works
Coordinated interactions between hippocampal Ripples and Cortical Spindles during Slow-Wave Sleep
Siapas, A. G., & Wilson, M. A. (1998) · Neuron · doi:10.1016/s0896-6273(00)80629-7 · Cited by 1,052 · see citing works
Organizing principles for a diversity of GABAergic interneurons and synapses in the neocortex
Gupta, A., Wang, Y., & Markram, H. (2000) · Science · doi:10.1126/science.287.5451.273 · Cited by 1,036 · see citing works
Akbarian, S. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950160008002 · Cited by 1,002 · see citing works
Schizophrenics Show Spatial Working Memory Deficits
Park, S. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820120063009 · Cited by 946 · see citing works
Intracellular Features Predicted by Extracellular Recordings in the Hippocampus In Vivo
Henze, D. A., Borhegyi, Z., Csicsvari, J., Mamiya, A., Harris, K. D., & Buzsáki, G. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.84.1.390 · Cited by 942 · see citing works
Hashimoto, T., Volk, D. W., Eggan, S. M., Mirnics, K., Pierri, J. N., Sun, Z., Sampson, A. R., & Lewis, D. A. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-15-06315.2003 · Cited by 938 · see citing works
Gray, C. M., & McCormick, D. A. (1996) · Science · doi:10.1126/science.274.5284.109 · Cited by 906 · see citing works
Abnormally High Neuronal Density in the Schizophrenic Cortex
Selemon, L. D. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950220015005 · Cited by 876 · see citing works
Jay, T. M., & Witter, M. P. (1991) · The Journal of Comparative Neurology · doi:10.1002/cne.903130404 · Cited by 841 · see citing works
Regional and cellular fractionation of working memory
Goldman‐Rakic, P. S. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.13473 · Cited by 810 · see citing works
Goldman‐Rakic, P. S., Selemon, L. D., & Schwartz, M. L. (1984) · Neuroscience · doi:10.1016/0306-4522(84)90166-0 · Cited by 782 · see citing works
Response properties of vibrissa units in rat SI somatosensory neocortex
Simons, D. J. (1978) · Journal of Neurophysiology · doi:10.1152/jn.1978.41.3.798 · Cited by 771 · see citing works
Floresco, S., Seamans, J. K., & Phillips, A. G. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-05-01880.1997 · Cited by 734 · see citing works
Pinault, D. (1996) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(95)00144-1 · Cited by 720 · see citing works
Lipska, B. K., Jaskiw, G. E., & Weinberger, D. R. (1993) · Neuropsychopharmacology · doi:10.1038/npp.1993.44 · Cited by 697 · see citing works
Mountcastle, V. B., Talbot, W. H., Sakata, H., & Hyvärinen, J. (1969) · Journal of Neurophysiology · doi:10.1152/jn.1969.32.3.452 · Cited by 683 · see citing works
Hippocampal Efferents Reach Widespread Areas of Cerebral Cortex and Amygdala in the Rhesus Monkey
Rosene, D. L., & Hoesen, G. W. V. (1977) · Science · doi:10.1126/science.410102 · Cited by 678 · see citing works
Integrator or coincidence detector? The role of the cortical neuron revisited
Peter König, B., Engel, A. K., & Singer, W. (1996) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)80019-1 · Cited by 674 · see citing works
Kawaguchi, Y., & Kubota, Y. (1993) · Journal of Neurophysiology · doi:10.1152/jn.1993.70.1.387 · Cited by 558 · see citing works
Kawaguchi, Y. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-04-02638.1995 · Cited by 533 · see citing works
A direct projection from Ammon's horn to prefrontal cortex in the rat
Swanson, L. W. (1981) · Brain Research · doi:10.1016/0006-8993(81)90192-x · Cited by 533 · see citing works
Feed-forward inhibition in the hippocampal formation
BUZSAKI, G. (1984) · Progress in Neurobiology · doi:10.1016/0301-0082(84)90023-6 · Cited by 453 · see citing works
Feldmeyer, D., Egger, V., Lübke, J., & Sakmann, B. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.00169.x · Cited by 441 · see citing works
Parvalbumin-immunoreactive neurons are reduced in the prefrontal cortex of schizophrenics
BEASLEY, C., & REYNOLDS, G. (1997) · Schizophrenia Research · doi:10.1016/s0920-9964(96)00122-3 · Cited by 426 · see citing works
Thomson, A. M. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.9.936 · Cited by 420 · see citing works
Dopamine gates LTP induction in lateral amygdala by suppressing feedforward inhibition
Bissière, S., Humeau, Y., & Lüthi, A. (2003) · Nature Neuroscience · doi:10.1038/nn1058 · Cited by 415 · see citing works
Rao, S. G., Williams, G. V., & Goldman-Rakic, P. S. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-01-00485.2000 · Cited by 407 · see citing works
Kawaguchi, Y. (1993) · Journal of Neurophysiology · doi:10.1152/jn.1993.69.2.416 · Cited by 390 · see citing works
Distal Initiation and Active Propagation of Action Potentials in Interneuron Dendrites
Martina, M., Vida, I., & Jonas, P. (2000) · Science · doi:10.1126/science.287.5451.295 · Cited by 375 · see citing works
Fast-spike Interneurons and Feedforward Inhibition in Awake Sensory Neocortex
Swadlow, H. A. (2002) · Cerebral Cortex · doi:10.1093/cercor/13.1.25 · Cited by 354 · see citing works
A role for inhibition in shaping the temporal flow of information in prefrontal cortex
Constantinidis, C., Williams, G. V., & Goldman-Rakic, P. S. (2002) · Nature Neuroscience · doi:10.1038/nn799 · Cited by 348 · see citing works
Porter, J. T., Johnson, C. K., & Agmon, A. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-08-02699.2001 · Cited by 344 · see citing works
Miles, R. (1990) · The Journal of Physiology · doi:10.1113/jphysiol.1990.sp018200 · Cited by 315 · see citing works
Neuroanatomical bases of spatial memory
Becker, J. T., Walker, J. A., & Olton, D. S. (1980) · Brain Research · doi:10.1016/0006-8993(80)90922-1 · Cited by 308 · see citing works
Selectivity of the hippocampal projection to the prelimbic area of the prefrontal cortex in the rat
Jay, T. M., Glowinski, J., & Thierry, A. M. (1989) · Brain Research · doi:10.1016/0006-8993(89)91464-9 · Cited by 295 · see citing works
Self-citationBenes, F. M., Vincent, S. L., Marie, A. S., & Khan, Y. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00328-4 · Cited by 274 · see citing works
GABAergic local circuit neurons and prefrontal cortical dysfunction in schizophrenia
Lewis, D. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00042-9 · Cited by 257 · see citing works
Steriade, M., Timofeev, I., Dürmüller, N., & Grenier, F. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.1.483 · Cited by 254 · see citing works
Du, J., Zhang, L., Weiser, M., Rudy, B., & McBain, C. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-02-00506.1996 · Cited by 246 · see citing works
Ferino, F., Thierry, A. M., & Glowinski, J. (1987) · Experimental Brain Research · doi:10.1007/bf00236315 · Cited by 246 · see citing works
Self-citationDifferentially Interconnected Networks of GABAergic Interneurons in the Visual Cortex of the Cat
Tamás, G., Somogyi, P., & Buhl, E. H. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-11-04255.1998 · Cited by 242 · see citing works
Jay, T. M., Thierry, A., Wiklund, L., & Glowinski, J. (1992) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1992.tb00154.x · Cited by 187 · see citing works
Self-citationThe effects of fornix and medial prefrontal lesions on delayed non-matching-to-sample by rats
Shaw, C., & Aggleton, J. P. (1993) · Behavioural Brain Research · doi:10.1016/0166-4328(93)90051-q · Cited by 181 · see citing works
Akbarian, S., Huntsman, M. M., Kim, J. J., Tafazzoli, A., Potkin, S. G., Bunney, W. E., & Jones, E. G. (1995) · Cerebral Cortex · doi:10.1093/cercor/5.6.550 · Cited by 181 · see citing works
Delatour, B., & Gisquet-Verrier, P. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(99)00168-0 · Cited by 170 · see citing works
Stress-induced activation of nitric oxide-producing neurons in the rat brain
Krukoff, T. L., & Khalili, P. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19970127)377:4 · Cited by 167 · see citing works
Dégenètais, E. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.1.1 · Cited by 152 · see citing works
Self-citationGABAergic neuronal subtypes in the human frontal cortex — development and deficits in schizophrenia
Reynolds, G. P., & Beasley, C. L. (2001) · Journal of Chemical Neuroanatomy · doi:10.1016/s0891-0618(01)00113-2 · Cited by 138 · see citing works
Pennartz, C. M. A., & Kitai, S. (1991) · Journal of Neuroscience · doi:10.1523/jneurosci.11-09-02838.1991 · Cited by 137 · see citing works
Comparisons of behavioral effects of hippocampal and prefrontal cortex lesions in the rat.
Nonneman, A. J., Voigt, J., & Kolb, B. E. (1974) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0036864 · Cited by 136 · see citing works
Angulo, M. C., Lambolez, B., Audinat, É., Hestrin, S., & Rossier, J. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-17-06685.1997 · Cited by 136 · see citing works
Dégenètais, E. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.7.782 · Cited by 127 · see citing works
Self-citationActivity of different classes of neurons of the motor cortex during locomotion
Beloozerova, I. N., Sirota, M. G., & Swadlow, H. A. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-03-01087.2003 · Cited by 126 · see citing works
Gabbott, P., Headlam, A., & Busby, S. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02487-3 · Cited by 101 · see citing works
Mulder, A. B., Nordquist, R. E., Örgüt, O., & Pennartz, C. M. A. (2003) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.09.016 · Cited by 84 · see citing works
The Influence of Single VB Thalamocortical Impulses on Barrel Columns of Rabbit Somatosensory Cortex
Swadlow, H. A., & Gusev, A. G. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.5.2802 · Cited by 84 · see citing works
de Bruin, J. P. C., Feenstra, M. G. P., Broersen, L. M., van Leeuwen, M., Arens, C., de Vries, S. I., & Joosten, R. N. J. M. A. (2000) · Progress in brain research · doi:10.1016/s0079-6123(00)26010-x · Cited by 72 · see citing works
Interhemispheric and subcortical collaterals of medial prefrontal cortical neurons in the rat
Ferino, F., Thierry, A. M., Saffroy, M., & Glowinski, J. (1987) · Brain Research · doi:10.1016/0006-8993(87)90450-1 · Cited by 72 · see citing works
Self-citationUnit activity of the medial wall of the frontal cortex during delayed performance in rats
Batuev, A. S. (1990) · Behavioural Brain Research · doi:10.1016/0166-4328(90)90145-5 · Cited by 67 · see citing works
Sakurai, Y., & Sugimoto, S. (1985) · Behavioural Brain Research · doi:10.1016/0166-4328(85)90045-2 · Cited by 56 · see citing works
Behavioral effects of large and small lesions of the rat medial frontal cortex
Silva, M. G., Boyle, M. A., Finger, S., Numan, B., Bouzrara, A., & Almli, C. R. (1986) · Experimental Brain Research · doi:10.1007/bf00243840 · Cited by 34 · see citing works
Large and small medial frontal cortex lesions and spatial performance of the rat
Wolf, C., Waksman, D., Finger, S., & Almli, C. R. (1987) · Brain Research Bulletin · doi:10.1016/0361-9230(87)90025-6 · Cited by 32 · see citing works
Chandelier cells: shedding light on altered cortical circuitry in schizophrenia
Lewis, D. A. (1998) · Molecular Psychiatry · doi:10.1038/sj.mp.4000469 · Cited by 17 · see citing works
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Homayoun, H., & Moghaddam, B. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.2213-07.2007 · Cited by 1,231 · see citing works
Prefrontal phase locking to hippocampal theta oscillations
Siapas, A. G., Lubenov, E. V., & Wilson, M. A. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.028 · Cited by 1,014 · see citing works
Entrainment of Neocortical Neurons and Gamma Oscillations by the Hippocampal Theta Rhythm
Sirota, A., Montgomery, S., Fujisawa, S., Isomura, Y., Zugaro, M., & Buzsáki, G. (2008) · Neuron · doi:10.1016/j.neuron.2008.09.014 · Cited by 1,015 · see citing works
Benchenane, K., Peyrache, A., Khamassi, M., Tierney, P. L., Gioanni, Y., Battaglia, F. P., & Wiener, S. I. (2010) · Neuron · doi:10.1016/j.neuron.2010.05.013 · Cited by 872 · see citing works
Adhikari, A., Topiwala, M. A., & Gordon, J. A. (2010) · Neuron · doi:10.1016/j.neuron.2009.12.002 · Cited by 729 · see citing works
The prefrontal cortex as a key target of the maladaptive response to stress
Cerqueira, J. J., Mailliet, F., Almeida, O. F. X., Jay, T. M., & Sousa, N. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.4372-06.2007 · Cited by 599 · see citing works
Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression
Courtin, J., Chaudun, F., Rozeske, R. R., Karalis, N., Gonzalez-Campo, C., Wurtz, H., Abdi, A., Baufreton, J., Bienvenu, T. C. M., & Herry, C. (2014) · Nature · doi:10.1038/nature12755 · Cited by 524 · see citing works
Stress-induced prefrontal reorganization and executive dysfunction in rodents
Holmes, A., & Wellman, C. L. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.11.005 · Cited by 469 · see citing works
Oscillations in the prefrontal cortex: a gateway to memory and attention
Benchenane, K., Tiesinga, P. H., & Battaglia, F. P. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.01.004 · Cited by 366 · see citing works
Goriounova, N. A., & Mansvelder, H. D. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a012120 · Cited by 307 · see citing works
“Feedforward inhibition in the PFC plays an important role in the integration of hippocampal inputs, which enter the PFC through superficial layers (Jay and Witter 1991; Tierney et al. 2004).”
BackgroundPrefrontal-Hippocampal Interactions in Memory and Emotion
Jin, J., & Maren, S. (2015) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2015.00170 · Cited by 313 · see citing works
“…area CA1 or the subiculum produces a monosynaptic excitatory postsynaptic potential (EPSP) followed by fast and slow inhibitory postsynaptic potentials (IPSPs); the latter are due to both feedforward (Jay et al., 1992; Tierney et al., 2004) and feedback inhibition (Dégenètais et al., 2003).”
BackgroundState-dependent spike-timing relationships between hippocampal and prefrontal circuits during sleep
Wierzynski, C. M., Lubenov, E. V., Gu, M., & Siapas, A. G. (2009) · Neuron · doi:10.1016/j.neuron.2009.01.011 · Cited by 289 · see citing works
Sierra‐Mercado, D., Corcoran, K. A., Lebrón‐Milad, K., & Quirk, G. J. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05014.x · Cited by 255 · see citing works
Anderson, K. L., Rajagovindan, R., Ghacibeh, G. A., Meador, K. J., & Ding, M. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhp223 · Cited by 222 · see citing works
Marek, R., Jin, J., Goode, T. D., Giustino, T. F., Wang, Q., Acca, G. M., Holehonnur, R., Ploski, J. E., Fitzgerald, P. J., Lynagh, T., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0073-9 · Cited by 226 · see citing works
Floresco, S. B., & Tse, M. T. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5474-06.2007 · Cited by 204 · see citing works
Brockmann, M. D., Pöschel, B., Cichon, N., & Hanganu-Opatz, I. L. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.041 · Cited by 186 · see citing works
Perry, J. L., Joseph, J. E., Jiang, Y., Zimmerman, R. S., Kelly, T. H., Darna, M., Huettl, P., Dwoskin, L. P., & Bardo, M. T. (2011) · Brain Research Reviews · doi:10.1016/j.brainresrev.2010.09.001 · Cited by 180 · see citing works
Chao, O. Y., de Souza Silva, M. A., Yang, Y.-M., & Huston, J. P. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.04.007 · Cited by 158 · see citing works
Llado-Pelfort, L., Santana, N., Ghisi, V., Artigas, F., & Celada, P. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhr220 · Cited by 156 · see citing works
Di Pietro, N. C., Black, Y. D., & Kantak, K. M. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05193.x · Cited by 107 · see citing works
de Novellis, V., Vita, D., Gatta, L., Luongo, L., Bellini, G., De Chiaro, M., Marabese, I., Siniscalco, D., Boccella, S., Piscitelli, F., et al. (2011) · Molecular Pain · doi:10.1186/1744-8069-7-7 · Cited by 90 · see citing works
Juárez, I., Gratton, A., & Flores, G. (2008) · Journal of Comparative Neurology · doi:10.1002/cne.21651 · Cited by 89 · see citing works
Lagler, M., Ozdemir, A. T., Lagoun, S., Malagon-Vina, H., Borhegyi, Z., Hauer, R., Jelem, A., & Klausberger, T. (2016) · Neuron · doi:10.1016/j.neuron.2016.08.010 · Cited by 67 · see citing works
Goriounova, N. A., & Mansvelder, H. D. (2012) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2012.00003 · Cited by 65 · see citing works
Chronic stress disrupts neural coherence between cortico-limbic structures
Oliveira, J. F., Dias, N. S., Correia, M., Gama-Pereira, F., Sardinha, V. M., Lima, A., Oliveira, A. F., Jacinto, L. R., Ferreira, D. S., Silva, A. M., et al. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00010 · Cited by 55 · see citing works
Altered short-term plasticity in the prefrontal cortex after early life seizures
Hernan, A. E., Holmes, G. L., Isaev, D., Scott, R. C., & Isaeva, E. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.10.007 · Cited by 49 · see citing works
Pathways for Contextual Memory: The Primate Hippocampal Pathway to Anterior Cingulate Cortex
Wang, J., John, Y., & Barbas, H. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhaa333 · Cited by 39 · see citing works
Amygdala Inputs to the Prefrontal Cortex Elicit Heterosynaptic Suppression of Hippocampal Inputs
Tejeda, H. A., & O'Donnell, P. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.0837-14.2014 · Cited by 11 · see citing works
- Authors
- Tierney, P. L., Dégenètais, E., Thierry, A., Glowinski, J., & Gioanni, Y.
- Affiliations
- Inserm (FR)
- Corresponding author
- Gioanni, Yves
- Venue
- European Journal of Neuroscience
- Publisher
- Wiley
- Published
- 2004-06-21
- Volume
- 20
- Issue
- 2
- Pages
- 514-524
- ISSN
- 0953-816X (ISSN-L)
- 1460-9568
- OpenAlex
- W1992991285
- Cited by
- 192
- References
- 71
- Citations by year
- 2026: 1 · 2025: 9 · 2024: 2 · 2023: 8 · 2022: 6 · 2021: 1 · 2020: 9 · 2019: 7 · 2018: 10 · 2017: 9 · 2016: 3 · 2015: 14 · 2014: 11 · 2013: 10 · 2012: 13
- FWCI
- 5.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministère de l'Enseignement Supérieur et de la Recherche
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- hippocampus, prefrontal cortex, hippocampal interneurons, pyramidal neurons, feedforward inhibition, action potential duration, action potential bursting, prelimbic cortex, hippocampal output, neuronal synchronization
- MeSH terms
- Action Potentials, Animals, Cell Count, Electric Stimulation, Hippocampus, Interneurons, Male, Membrane Potentials, Neural Inhibition, Time Factors, Rats, Sprague-Dawley, Prefrontal Cortex, Pyramidal Cells, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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