The DOI matches its Crossref record; 36 of the 37 references it cites were found in a registry or an index.
The place of the hippocampus in fear conditioning
Abstract
Pavlovian fear conditioning is a phenomenon amenable to laboratory analysis of the neurobiology of fear and the investigation of neural mechanisms of learning and memory. Investigators have made much progress in delineating the neurocircuitry and neurochemistry of fear conditioning. The place of the hippocampus in context fear remains a controversial issue. In this review, we examine the evidence that the hippocampus plays a role in fear conditioning. We then critically examine hypotheses concerning its exact role in learning and memory for cued and context fear conditioning.
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“The hippocampus is an important component of contextual fear conditioning (Phillips and LeDoux [181]; Maren [182]; Sanders et al. [183]; Rudy et al. [184]).”
From The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law (2007) · cites this paper as Sanders et al. [183]
In the citing paper
“It is well known that hippocampal damage or inactivation can interfere with contextual, but not cued, fear conditioning (Phillips and LeDoux [181]; Maren [182]; Sanders et al. [183]; Rudy et al. [184]).”
From The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law (2007) · cites this paper as Sanders et al. [183]
In the citing paper
“Thus, the performance of rats given prolonged pretraining stress was equivalent to the severe contextual memory impairment which has been reported in rats with an inactivated or damaged hippocampus (Phillips and LeDoux [181]; Maren [182]; Sanders et al. [183]; Rudy et al. [184]).”
From The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law (2007) · cites this paper as Sanders et al. [183]
Citations
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“A critical component of the emotion-induced enhancement of LTP involves the activation of the hippocampus by the amygdala.”
Background
Metadata
- Authors
- Sanders, M. J., Wiltgen, B. J., & Fanselow, M. S.
- Affiliations
- University of California, Los Angeles (US)
- Corresponding author
- Fanselow, Michael S
- Venue
- European Journal of Pharmacology
- Publisher
- Elsevier BV
- Published
- 2003-02
- Volume
- 463
- Issue
- 1-3
- Pages
- 217-223
- ISSN
- 0014-2999 (ISSN-L)
- OpenAlex
- W1964772923
- Cited by
- 316
- References
- 37
- Citations by year
- 2026: 7 · 2025: 5 · 2024: 7 · 2023: 8 · 2022: 12 · 2021: 7 · 2020: 10 · 2019: 12 · 2018: 9 · 2017: 15 · 2016: 10 · 2015: 13 · 2014: 14 · 2013: 14 · 2012: 14
- FWCI
- 10.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation
- National Institute of Mental Health (R01-MH62122, R01MH062122)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Keywords
- hippocampus, fear conditioning, cued fear, learning and memory, neurobiology of fear, neurocircuitry, neurochemistry
- MeSH terms
- Animals, Conditioning, Psychological, Conditioning, Classical, Fear, Hippocampus, Memory, Nerve Net
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