Cited by 305Redox biology and oxidative stressNitric Oxide and Endothelin EffectsAntioxidant Activity and Oxidative Stress

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Protection against peroxynitrite

Arteel, Gavin E., Briviba, Karlis, Sies, Helmut·1999·FEBS Letters

DOI 10.1016/s0014-5793(99)00073-3

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Abstract

Peroxynitrite formed in vivo from superoxide and nitric oxide can mediate oxidation, nitration, or nitrosation reactions, leading to impaired function, toxicity, and alterations in signaling pathways. Protection against peroxynitrite is important for defense of normal tissue, especially during inflammation. Biological protection against peroxynitrite is organized in three categories: prevention, interception, and repair. Prevention is the control of the formation of peroxynitrite precursors, nitric oxide and superoxide. Interception is by direct reaction with peroxynitrite, leading to non‐toxic products. In this regard, organoselenium compounds, metalloporphyrin derivatives, and peroxidases (e.g. glutathione peroxidase and myeloperoxidase) exhibit high second‐order rate constants with peroxynitrite. Ebselen, like glutathione peroxidase, protects in a catalytic fashion utilizing glutathione as reductant in the peroxynitrite reductase reaction. Protection by metalloporphyrins can be maintained through glutathione or ascorbate. Repair processes remove damaged products and restitute intact biomolecules.

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Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., & Freeman, B. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1620 · Cited by 7,029
Peroxynitrite oxidation of sulfhydryls.
Radí, R., Beckman, J. S., Bush, K., & Freeman, B. Α. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)64313-7 · Cited by 2,492
Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
Radí, R., Beckman, J. S., Bush, K. M., & Freeman, B. Α. (1991) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(91)90224-7 · Cited by 2,201
The reaction of NO with superoxide
Huie, R. E., & Padmaja, S. (1993) · Free Radical Research Communications · doi:10.3109/10715769309145868 · Cited by 2,121
Strategies of antioxidant defense
SIES, H. (1993) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1993.tb18025.x · Cited by 1,976
Self-citation
Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide
Koppenol, W. H., Moreno, J. J., Pryor, W. A., Ischiropoulos, H., & Beckman, J. S. (1992) · Chemical Research in Toxicology · doi:10.1021/tx00030a017 · Cited by 1,338
Extensive Nitration of Protein Tyrosines in Human Atherosclerosis Detected by Immunohistochemistry
Beckman, J. S., Ye, Y. Z., Anderson, P. G., Chen, J., Accavitti, M. A., Tarpey, M. M., & White, C. R. (1994) · Biological Chemistry Hoppe-Seyler · doi:10.1515/bchm3.1994.375.2.81 · Cited by 1,122
Peroxynitrite formation from macrophage-derived nitric oxide
Ischiropoulos, H., Zhu, L., & Beckman, J. S. (1992) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(92)90433-w · Cited by 1,099
Methionine residues as endogenous antioxidants in proteins
Levine, R. L., Mosoni, L., Berlett, B. S., & Stadtman, E. R. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.26.15036 · Cited by 1,041
Biological Tyrosine Nitration: A Pathophysiological Function of Nitric Oxide and Reactive Oxygen Species
Ischiropoulos, H. (1998) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1998.0755 · Cited by 1,025

Show all 74 references

Research works printed but not linked: 3

Ogawa A. Yoshimoto T. Kikuchi H. Sano K. Saito I. Yamaguchi T. and Yasuhara H. (1998) Cerebrovasc. Dis. (in press).
Arteel G.E., 1998, Biol. Chem., 379, 1201
da Silva E.L., 1998, Biochem. Mol. Biol. Int., 46, 343

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Authors: Arteel, G. E., Briviba, K., & Sies, H.
Affiliations: Heinrich Heine University Düsseldorf (DE)
Corresponding author: Sies, Helmut
ORCID: Arteel, Gavin E.
Briviba, Karlis
Sies, Helmut
Venue: FEBS Letters
Publisher: Wiley
Published: 1999-02-26
Volume: 445
Issue: 2-3
Pages: 226-230
ISSN: 0014-5793 (ISSN-L)
1873-3468
DOI: 10.1016/s0014-5793(99)00073-3
OpenAlex: W2027107445
Cited by: 305
References: 74
Citations by year: 2026: 2 · 2025: 3 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 11 · 2020: 4 · 2019: 1 · 2018: 5 · 2017: 3 · 2016: 7 · 2015: 8 · 2014: 10 · 2013: 13 · 2012: 10
FWCI: 2.34
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 31 d)
Locations: FEBS Letters (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
Keywords: peroxynitrite, peroxynitrite scavenging, superoxide, nitric oxide, ebselen, glutathione peroxidase, myeloperoxidase, metalloporphyrins, organoselenium compounds, nitration, nitrosation, oxidative stress, inflammation
MeSH terms: Animals, Humans, Nitrates, Molecular Structure, Oxidants

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