Anaerobic Degradation of Choline
Open accessIntegrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Gut microbial metabolism of choline results in the production of trimethylamine (TMA).
“Previous studies have established that gut microbial metabolism of choline results in the production of trimethylamine (TMA) (12–14).”
Cites
THE COLORIMETRIC DETERMINATION OF PHOSPHORUS
Fiske, C. H., & Subbarow, Y. (1925) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)84756-1 · Cited by 19,155 · see citing works
COENZYME A FUNCTION IN AND ACETYL TRANSFER BY THE PHOSPHOTRANSACETYLASE SYSTEM
Stadtman, E. R., Novelli, G. D., & Lipmann, F. A. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50986-8 · Cited by 505 · see citing works
ENZYMATIC PHOSPHORYLATION OF ACETATE
Rose, I. A., GRUNBERG‐MANAGO, M., Korey, S. R., & Ochoa, S. (1954) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71161-7 · Cited by 387 · see citing works
ASPARTIC β-SEMIALDEHYDE DEHYDROGENASE AND ASPARTIC β-SEMIALDEHYDE
Black, S., & Wright, N. G. (1955) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71042-9 · Cited by 249 · see citing works
ALDEHYDE DEHYDROGENASE, A DIPHOSPHOPYRIDINE NUCLEOTIDE-LINKED ENZYME
Racker, E. (1949) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)57033-2 · Cited by 205 · see citing works
THE OXIDATION OF ACETALDEHYDE TO ACETYL COENZYME A
Burton, R. M., & Stadtman, E. R. (1953) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66200-3 · Cited by 170 · see citing works
Black, S. (1951) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(51)80013-4 · Cited by 167 · see citing works
ANAEROBIC DEGRADATION OF CHOLINE I. , Vibrio cholinicus n. sp
Hayward, H. R., & Stadtman, T. C. (1959) · Journal of Bacteriology · doi:10.1128/jb.78.4.557-561.1959 · Cited by 68 · see citing works
Self-citationJakoby, W. B. (1958) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)70376-1 · Cited by 59 · see citing works
The Separation of Choline Esters by Paper Chromatography.
Augustinsson, K., Grahn, M., Fex, H. F. D., Högberg, B., Linderot, T., & Rosenberg, T. (1953) · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · doi:10.3891/acta.chem.scand.07-0906 · Cited by 49 · see citing works
Anaerobic Degradation of Choline
Hayward, H. R., & Stadtman, T. C. (1960) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69563-8 · Cited by 34 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Romano, K. A., Vivas, E. I., Amador-Noguez, D., & Rey, F. E. (2015) · mBio · doi:10.1128/mbio.02481-14 · Cited by 777 · see citing works
Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme
Craciun, S., & Balskus, E. P. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1215689109 · Cited by 701 · see citing works
Dissimilatory Sulfate- and Sulfur-Reducing Prokaryotes
Rabus, R., Hansen, T. A., & Widdel, F. (2013) · Springer eBooks · doi:10.1007/978-3-642-30141-4_70 · Cited by 444 · see citing works
Rabus, R., Venceslau, S. S., Wöhlbrand, L., Voordouw, G., Wall, J. D., & Pereira, I. A. C. (2015) · Advances in microbial physiology/Advances in Microbial Physiology · doi:10.1016/bs.ampbs.2015.05.002 · Cited by 355 · see citing works
Dissimilatory Sulfate- and Sulfur-Reducing Prokaryotes
Rabus, R., Hansen, T. A., & Widdel, F. (2006) · Springer eBooks · doi:10.1007/0-387-30742-7_22 · Cited by 265 · see citing works
Physiology and ecology of the sulphate‐reducing bacteria
Gibson, G. R. (1990) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1990.tb01575.x · Cited by 234 · see citing works
Osmotic control of glycine betaine biosynthesis and degradation in Rhizobium meliloti
Smith, L. T., Pocard, J., Bernard, T., & Rudulier, D. L. (1988) · Journal of Bacteriology · doi:10.1128/jb.170.7.3142-3149.1988 · Cited by 232 · see citing works
Martínez-del Campo, A., Bodea, S., Hamer, H. A., Marks, J. A., Haiser, H. J., Turnbaugh, P. J., & Balskus, E. P. (2015) · mBio · doi:10.1128/mbio.00042-15 · Cited by 224 · see citing works
Metabolism of sulfate-reducing prokaryotes
Hansen, T. A. (1994) · Antonie van Leeuwenhoek · doi:10.1007/bf00871638 · Cited by 197 · see citing works
Recent advances in the study of the sulfate-reducing bacteria
Postgate, J. R. (1965) · Bacteriological Reviews · doi:10.1128/br.29.4.425-441.1965 · Cited by 174 · see citing works
Zeisel, S. H., daCosta, K. A., Youssef, M., & Hensey, S. (1989) · The Journal of Nutrition · doi:10.1093/jn/119.5.800 · Cited by 151 · see citing works
The Clostridial Fermentations of Choline and Ethanolamine
Bradbeer, C. (1965) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)97007-9 · Cited by 116 · see citing works
The aerobic decomposition of choline by microorganisms
Kortstee, G. J. J. (1970) · Archives of Microbiology · doi:10.1007/bf00410157 · Cited by 81 · see citing works
Volatile constituents of dog (Canis familiaris) and coyote (Canis latrans) anal sacs
Preti, G., MUETTERTIES, E. L., FURMAN, J. M. R., Kennelly, J. J., & Johns, B. E. (1976) · Journal of Chemical Ecology · doi:10.1007/bf00987740 · Cited by 75 · see citing works
Degradation of various amine compounds by mesophilic clostridia
M�ller, B., Hippe, H., & Gottschalk, G. (1986) · Archives of Microbiology · doi:10.1007/bf00413032 · Cited by 50 · see citing works
Niizeki, N., Daikoku, T., Hirata, T., El-Shourbagy, I., Song, X., & Sakaguchi, M. (2002) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s1096-4959(01)00508-5 · Cited by 38 · see citing works
Fixation of Dinitrogen by Free-Living Microorganisms
Dalton, H. (1974) · CRC Critical Reviews in Microbiology · doi:10.3109/10408417409108750 · Cited by 37 · see citing works
Choline and N , N -Dimethylethanolamine as Direct Substrates for Methanogens
Watkins, A. J., Roussel, E. G., Webster, G., Parkes, R. J., & Sass, H. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.01941-12 · Cited by 36 · see citing works
Role of Acetaldehyde in Metabolism: A Review 1. Enzymes Catalyzing Reactions Involving Acetaldehyde
Lees, G. J., & Jago, G. R. (1978) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(78)83708-4 · Cited by 35 · see citing works
Converging on a mechanism for choline degradation
Thibodeaux, C. J., & van der Donk, W. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219534110 · Cited by 28 · see citing works
Significance of yeast peroxisomes in the metabolism of choline and ethanolamine
Zwart, K. B., Marten Veenhuis, A., & Harder, W. (1983) · Antonie van Leeuwenhoek · doi:10.1007/bf00399317 · Cited by 27 · see citing works
Chao, C.-K., & Zeisel, S. H. (1990) · The Journal of Nutritional Biochemistry · doi:10.1016/0955-2863(90)90055-p · Cited by 23 · see citing works
Aerobic degradation of choline by <i>Proteus mirabilis</i>: enzymatic requirements and pathway
Sandhu, S. S., & Chase Jr., T. (1986) · Canadian Journal of Microbiology · doi:10.1139/m86-135 · Cited by 18 · see citing works
Biotransformation of alkanoylcholines under methanogenic conditions
Watson, M. K., Tezel, U., & Pavlostathis, S. G. (2012) · Water Research · doi:10.1016/j.watres.2012.03.021 · Cited by 17 · see citing works
Mechanism of biosynthesis of trimethylamine oxide in tilapia reared under seawater conditions
Niizeki, N., Daikoku, T., Hirata, T., El-Shourbagy, I., Song, X., & Sakaguchi, M. (2003) · Fisheries Science · doi:10.1046/j.1444-2906.2003.00590.x · Cited by 15 · see citing works
Über die Abbaufähigkeit bestimmterPseudomonas-Species für (—)-Carnitin
Strack, E., Aurich, H., & Grüner, E. (1964) · Journal of Basic Microbiology · doi:10.1002/jobm.3630040208 · Cited by 12 · see citing works
15 B12 Coenzyme-Dependent Amino Group Migrations
Stadtman, T. C. (1972) · The Enzymes · doi:10.1016/s1874-6047(08)60050-5 · Cited by 11 · see citing works
Kaech, A., & Egli, T. W. (2001) · Systematic and Applied Microbiology · doi:10.1078/0723-2020-00043 · Cited by 10 · see citing works
Englard, S., Blanchard, J. S., & Miura-Fraboni, J. (1983) · Archives of Microbiology · doi:10.1007/bf00413486 · Cited by 10 · see citing works
Kaech, A., Vallotton, N., & Egli, T. W. (2005) · Systematic and Applied Microbiology · doi:10.1016/j.syapm.2004.12.004 · Cited by 9 · see citing works
Über die Abbaufähigkeit bestimmter Pseudomonas‐Species für (—)‐Carnitin
Strack, E., Aurich, H., & Grüner, E. (1964) · Zeitschrift für allgemeine Mikrobiologie · doi:10.1002/jobm.19640040208 · Cited by 8 · see citing works
Infrared Spectra of some Sulphate-Reducing Bacteria
Booth, G. H., Miller, J. D., Paisley, H. M., & Saleh, A. M. (1966) · Journal of General Microbiology · doi:10.1099/00221287-44-1-83 · Cited by 8 · see citing works
Ren, J., Zhou, Y., Zhou, Y., Zhou, C. Q., Li, Z., Lin, Q., & Huang, H. (2014) · Food and Bioprocess Technology · doi:10.1007/s11947-014-1394-7 · Cited by 7 · see citing works
HATT, H. D., & ZVIRBULIS, E. (1967) · International Journal of Systematic Bacteriology · doi:10.1099/00207713-17-2-171 · Cited by 7 · see citing works
Chen, P., Ho, C., Shahidi, F., & Pan, M. (2018) · Journal of Food Bioactives · doi:10.31665/jfb.2018.3151 · Cited by 6 · see citing works
Osmoregulation in Rhizobium Meliloti: Control of Glycine Betaine Biosynthesis and Catabolism
Rudulier, D. L., & Pocard, J. (1991) · Springer eBooks · doi:10.1007/978-1-4615-3730-4_11 · Cited by 1 · see citing works
Recent Advances intheStudyoftheSulfate-Reducing Bacteria
Postgate, J. R. (1965)
Dissimilation of Ethanol and Related Compounds by Desulfovibrio Strains
Hansen, T. A., & Kremer, D. R. (1990) · Springer eBooks · doi:10.1007/978-1-4613-0613-9_16
Epigenetics and Modification of Gene Expression in Metabolism
Heber, D. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-15315-0.00009-2
Steric and Electronic Effects in the Enzymatic Catalysis of Choline-TMA Lyase
Gogonea, V., & Hazen, S. L. (2025) · Biomolecules · doi:10.3390/biom16010037
- Authors
- Hayward, H. R.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Hayward, Hugh R.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1960-12
- Volume
- 235
- Issue
- 12
- Pages
- 3592-3596
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2406333640
- Cited by
- 40
- References
- 11
- Citations by year
- 2025: 1 · 2023: 1 · 2018: 1 · 2015: 3 · 2014: 1 · 2013: 1 · 2012: 4
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Biological Chemistry (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Steroid Chemistry and Biochemistry
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial metabolism and enzyme function
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Polyamine Metabolism and Applications
- Keywords
- choline, anaerobic biodegradation, quaternary ammonium compounds, microbial metabolism
- MeSH terms
- Acetaldehyde, Choline, Fermentation, Vibrio, Desulfovibrio desulfuricans
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review