Induction of Rat Hepatic N-Nitrosodimethylamine Demethylase by Acetone Is Due to Protein Stabilization

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

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P450 GENES: STRUCTURE, EVOLUTION, AND REGULATION

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Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme.

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Ethanol-, fasting-, and aceton-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies

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Identification of ethanol-inducible P-450 isozyme 3a as the acetone and acetol monooxygenase of rabbit microsomes.

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Mammalian cytochromes P-450

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Mechanisms of hydroxyl radical formation and ethanol oxidation by ethanol-inducible and other forms of rabbit liver microsomal cytochromes P-450.

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Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols.

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Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid.

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The induction of a specific form of cytochrome P-450 (P-450j) by fasting

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Stabilization of Cytochrome P450j Messenger Ribonucleic Acid in the Diabetic Rat

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Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture.

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Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures

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SUBFRACTIONATION AND COMPOSITION OF MICROSOMAL MEMBRANES: A REVIEW

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Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic rats

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Measurement of Protein Turnover in Rat Liver with [14C]Carbonate

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The rat P450IIE1 gene: complete intron and exon sequence, chromosome mapping, and correlation of developmental expression with specific 5' cytosine demethylation.

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Monoclonal antibodies to ethanol-induced rat liver cytochrome P-450 that metabolizes aniline and nitrosamines.

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[18] Methods for analysis of enzyme synthesis and degradation in animal tissues

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Synthesis and degradation of 3-methylcholanthrene-inducible cytochromes P-450 and their mRNAs in primary monolayer cultures of adult rat hepatocytes

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Comparison of different techniques for estimating rates of protein synthesis in vivo in healthy and bacteraemic rats

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The in vivo turnover of rat liver microsomal epoxide hydrolase and both the apoprotein and heme moieties of specific cytochrome P-450 isozymes

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Detection and purification of cytochromes P-450 in animal tissues with monoclonal antibodies.

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Inducers of cytochrome P-450d: Influence on microsomal catalytic activities and differential regulation by enzyme stabilization

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Cloning of a cDNA coding for P-450 LM3c from rabbit liver microsomes and regulation of its expression

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Hepatotoxicity and Mechanism of Action of Haloalkanes: Carbon Tetrachloride as a Toxicological Model

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Inhibition and Induction of Cytochrome P450 and the Clinical Implications

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CYP2E1 and oxidative liver injury by alcohol

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Human Cytochrome P450 Enzymes

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Role of CYP2E1 in the Hepatotoxicity of Acetaminophen

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Metabolic zonation of the liver: Regulation and implications for liver function

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Role of oxidative stress in alcohol-induced liver injury

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Inhibition and induction of human cytochrome P450 enzymes: current status

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Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1

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Phenobarbital induction of cytochrome P -450 gene expression

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Evolution of the P450 gene superfamily:

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Alcohol and the liver: 1994 update

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Role of Human Cytochromes P450 in the Metabolic Activation of Chemical Carcinogens and Toxins

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Molecular genetics of the P-450 superfamily

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Microsomal Ethanol‐Oxidizing System (MEOS): The First 30 Years (1968‐1998)–A Review

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Inhibition and induction of CYP enzymes in humans: an update

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Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury

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Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms

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Acetaminophen Hepatotoxicity: The First 35 Years

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Role of Oxidative Stress and Antioxidant Therapy in Alcoholic and Nonalcoholic Liver Diseases

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Ethanol Induces CYP2E1 by Protein Stabilization

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Developmental Expression of CYP2E1 in the Human Liver

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CYP induction-mediated drug interactions: in vitro assessment and clinical implications

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Bioactivation of Halogenated Hydrocarbons by Cytochrome P4502E1

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Mechanisms of cytochrome P450 induction

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Cytochromes P-450 in rats: structures, functions, properties and relevant human forms

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Oxidative stress and depletion of hepatic long-chain polyunsaturated fatty acids may contribute to nonalcoholic fatty liver disease

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Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA

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Zonation of hepatic cytochrome P-450 expression and regulation

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Peroxisome Proliferator-activated Receptor α Controls the Hepatic CYP4A Induction Adaptive Response to Starvation and Diabetes

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Expression of xenobiotic-metabolizing cytochrome P450 Forms in human full-term placenta

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CYP2E1

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Peroxisome proliferator-activated receptor ? protects against alcohol-induced liver damage

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Different Regulation and Expression of the Human CYP2E1 Gene Due to the Rsal Polymorphism in the 5'-Flanking Region1

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Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans

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Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion

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Human CYP2E1 is regulated by miR-378

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Peroxisome proliferator-activated receptor α protects against alcohol-induced liver damage

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Degradation of cytochrome P450 2E1: Selective loss after labilization of the enzyme

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Ethanol‐Inducible Cytochrome P450 (CYP2E1): Biochemistry, Molecular Biology and Clinical Relevance: 1996 Update

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Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications

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Ethanol and production of the hepatotoxic metabolite of acetaminophen in healthy adults

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Constitutive expression of hepatic cytochrome P450 genes

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The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading

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Cytochrome P450S and Alcoholic Liver Disease

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Cytochrome P450IIE1 Is Elevated in Lymphocytes from Poorly Controlled Insulin-Dependent Diabetics*

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Genetic Polymorphism in CYP2E1: Population Distribution of CYP2E1 Activity

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Regulation of Hepatic Microsomal Cytochrome P450IIE1 Level by Dietary Lipids and Carbohydrates in Rats

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Evidence of Proteasome-mediated Cytochrome P-450 Degradation

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CYP2E1 – Biochemical and Toxicological Aspects and Role in Alcohol-Induced Liver Injury

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Role of CYP2E1 in Mitochondrial Dysfunction and Hepatic Injury by Alcohol and Non-Alcoholic Substances

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Mechanisms of Ethanol-Drug-Nutrition Interactions

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Pre-translational regulation of cytochrome P450 genes is responsible for disease-specific changes of individual P450 enzymes among patients with cirrhosis

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A dual inhibition: microRNA-552 suppresses both transcription and translation of cytochrome P450 2E1

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P450 and Human Cancer

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The complex interaction between ethanol and acetaminophen*

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Transcriptional Control of the Rat Hepatic CYP2E1 Gene

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Protein Quality Control as a Strategy for Cellular Regulation: Lessons from Ubiquitin-Mediated Regulation of the Sterol Pathway

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Robust protein nitration contributes to acetaminophen-induced mitochondrial dysfunction and acute liver injury

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Noncoding microRNAs: small RNAs play a big role in regulation of ADME?

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Proteolytic Degradation of Heme-Modified Hepatic Cytochromes P450: A Role for Phosphorylation, Ubiquitination, and the 26S Proteasome?

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Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole

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CYP2E1 is Preferentially Expressed in Clara Cells of Murine Lung: Localization by in Situ Hybridization and Immunohistochemical Methods

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Expression and Distribution of Cytochrome P450 Enzymes in Male Rat Kidney: Effects of Ethanol, Acetone and Dietary Conditions

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Characterization of Cytochrome P4502E1 Turnover in Transfected HepG2 Cells Expressing Human CYP2E1

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Insulin Differentially Affects Xenobiotic-Enhanced, Cytochrome P-450 (CYP)2E1, CYP2B, CYP3A, and CYP4A Expression in Primary Cultured Rat Hepatocytes

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Endosulfan Elevates Testosterone Biotransformation and Clearance in CD-1 Mice

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Rapid decrease of cytochrome P-450IIE1 in primary hepatocyte culture and its maintenance by added 4-methylpyrazole

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Constitutive and Inducible Expression of Hepatic CYP2E1 in Leptin-deficient ob/ob Mice

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Nrf2 and antioxidant defense against CYP2E1 toxicity

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Induction of Cytochrome P450 Enzymes That Metabolize Xenobiotics

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CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury

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Functional Roles of Protein Nitration in Acute and Chronic Liver Diseases

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Acetone-dependent regulation of cytochrome P-450j (IIE1) and P-450b (IIB1) in rat liver

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Effects of acetone administration on drug-metabolizing enzymes in mice: presence of a high-affinity diethylnitrosamine de-ethylase

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Induction of a high affinity nitrosamine demethylase in rat liver microsomes by acetone and isopropanol

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Regulation of rat hepatic cytochrome P450IIE1 in primary monolayer hepatocyte culture

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Studies on the mechanisms of induction of N-nitrosodimethylamine demethylase by fasting, acetone, and ethanol

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