The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
General methods for the analysis of metabolic profiles of bile acids and related compounds in feces.
Open accessAbstract
A general method is described for the detailed qualitative and quantitative analysis of bile acids and related compounds from feces. The technique utilizes a novel combination of liquid-gel and liquid-solid extraction, lipophilic ion exchange chromatography, and capillary column gas-liquid chromatography coupled to mass spectrometry, which permits the detailed composition of bile acids in feces in terms of both the individual bile acids present and their mode of conjugation in the original fecal sample. The extraction, purification, and isolation procedures have been evaluated using fecal samples containing endogenous radioactive bile acid metabolites and from the addition of radiolabeled standards to fecal homogenates. The applicability of the general procedure is illustrated with examples from the analysis of bile acids and sterols in the feces collected from normal healthy subjects, patients with chronic diarrhea, and an adult female Sprague-Dawley rat. The flexibility of the method, and the general problems encountered in the extraction, purification, and isolation of bile acids and related classes of compounds from feces for subsequent analysis of gas-liquid chromatography are discussed in detail.
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Citations
Cites
Quantitative isolation and gas–liquid chromatographic analysis of total fecal bile acids
Grundy, S. M., Ahrens, E. H., & Miettinen, T. A. (1965) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39310-x · Cited by 883
Almé, B., Bremmelgaard, A., Sjövall, J., & Thomassen, P. (1977) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41684-0 · Cited by 491
Self-citationBreath test for altered bile-acid metabolism
Fromm, H., & Hofmann, A. F. (1971) · The Lancet · doi:10.1016/s0140-6736(71)80068-5 · Cited by 337
Quantitative analysis of fecal bile acids by gas-liquid chromatography
Makita, M., & Wells, W. W. (1963) · Analytical Biochemistry · doi:10.1016/0003-2697(63)90072-1 · Cited by 272
Shackleton, C. H. L., & Whitney, J. O. (1980) · Clinica Chimica Acta · doi:10.1016/0009-8981(80)90451-9 · Cited by 252
Bile acid sulfates. I. Synthesis of lithocholic acid sulfates and their identification in human bile
PALMER, R. H., & BOLT, M. G. (1971) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39454-2 · Cited by 220
Setchell, K. D. R., & Worthington, J. (1982) · Clinica Chimica Acta · doi:10.1016/0009-8981(82)90190-5 · Cited by 195
Self-citationEneroth, P., Gordon, B., Ryhage, R., & Sjövall, J. (1966) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39261-0 · Cited by 183
Self-citationGas-liquid chromatographic determination of human fecal bile acids
Evrard, E., & Janssen, G. (1968) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)43123-2 · Cited by 177
Setchell, K. D. R., & Matsui, A. (1983) · Clinica Chimica Acta · doi:10.1016/0009-8981(83)90070-0 · Cited by 176
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Diet rapidly and reproducibly alters the human gut microbiome
David, L. A., Maurice, C. F., Carmody, R. N., Gootenberg, D. B., Button, J. E., Wolfe, B. E., Ling, A. V., Devlin, A. S., Varma, Y., Fischbach, M. A., et al. (2014) · Nature · doi:10.1038/nature12820 · Cited by 10,100
Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
Lefebvre, P., Cariou, B., Lien, F., Kuipers, F., & Staels, B. (2009) · Physiological Reviews · doi:10.1152/physrev.00010.2008 · Cited by 1,678
Russell, D. W., & Setchell, K. D. R. (1992) · Biochemistry · doi:10.1021/bi00135a001 · Cited by 819
Diversification of host bile acids by members of the gut microbiota
Winston, J. A., & Theriot, C. M. (2020) · Gut Microbes · doi:10.1080/19490976.2019.1674124 · Cited by 587
A biosynthetic pathway for a prominent class of microbiota-derived bile acids
Devlin, A. S., & Fischbach, M. A. (2015) · Nature Chemical Biology · doi:10.1038/nchembio.1864 · Cited by 448
Metadata
- Authors
- Setchell, K. D., Lawson, A. M., Tanida, N., & Sjövall, J.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 1983-08
- Volume
- 24
- Issue
- 8
- Pages
- 1085-1100
- ISSN
- 0022-2275 (ISSN-L)
- OpenAlex
- W2340570492
- Cited by
- 285
- References
- 37
- FWCI
- 16.34
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Setchell, K. D., Lawson, A. M., Tanida, N., & Sjövall, J. (1983). General methods for the analysis of metabolic profiles of bile acids and related compounds in feces. Journal of Lipid Research. https://doi.org/10.1016/s0022-2275(20)37923-2
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
