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REACTIONS OF STRIPS OF RABBIT AORTA TO EPINEPHRINE, ISOPROPYLARTERENOL, SODIUM NITRITE AND OTHER DRUGS
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“In 1952 Furchgott and Bhadrakhom demonstrated the ability of nitrite to effect relaxation of pre-constricted aortic vessels, but the concentrations used where substantially higher than that found in physiological conditions (100 μM compared to normal levels of tens to hundreds of nanomolar) [27].”
From Mechanisms of nitrite bioactivation (2014) · cites this paper as [27]
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Metadata
- Authors
- Furchgott, R. F., & Bhadrakom, S.
- Affiliations
- Washington University in St. Louis (US)
- Venue
- The Journal of Pharmacology and Experimental Therapeutics
- Publisher
- Elsevier BV
- Published
- 1953-06
- Volume
- 108
- Issue
- 2
- Pages
- 129-143
- ISSN
- 0022-3565 (ISSN-L)
- OpenAlex
- W2302863210
- Cited by
- 655
- References
- 0
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 8 · 2018: 6 · 2017: 6 · 2016: 9 · 2015: 9 · 2014: 13 · 2013: 7 · 2012: 9
- FWCI
- 2.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Pharmacology and Experimental Therapeutics (publishedVersion)
- PubMed (publishedVersion)
- PubMed
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Health Sciences › Medicine › Surgery › Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Keywords
- rabbit aorta, epinephrine, isoproterenol, sodium nitrite, norepinephrine, histamine, acetylcholine, vascular smooth muscle contraction, drug sensitivity, drug antagonism
- MeSH terms
- Animals, Aorta, Epinephrine, Isoproterenol, Norepinephrine, Rabbits, Sodium Nitrite
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