Glycemic control and major depression in patients with type 1 and type 2 diabetes mellitus
Abstract
The current study evaluated the association of glycemic control and major depression in 33 type 1 and 39 type 2 diabetes mellitus patients. Type 1 patients with a lifetime history of major depression showed significantly worse glycemic control than patients without a history of psychiatric illness (t = 2.09; df = 31, p < 0.05). Type 2 diabetes patients with a lifetime history of major depression did not have significantly worse control than those with no history of psychiatric illness. Findings from this study indicate different relationships between lifetime major depression and glycemic control for patients with type 1 and type 2 diabetes. Treatment implications for glycemic control in type 1 and type 2 diabetes patients are discussed.
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The heterogeneity (I2) for the pooled prevalence of depressive disorders in people with type 1 diabetes based on interviews was 91.18%.
“| [20-23,29-31,34-39,41,42,44,45,48,52,53,55,58,59] | 18 | Interviews | 1250 | 14.35 | 10.65-18.05 | 91.18% |”
From Prevalence of mental disorders in people living with type 1 diabetes: A systematic literature review and meta-analysis (2023) · cites this paper as [36]
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Cites
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“All but one study examining the relationship between depression and glycemic control, to date, have been cross-sectional designs [ 2 , 4, 23].”
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“5% [1–11].”
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- Authors
- de Groot, M., Jacobson, A. M., Samson, J. A., & Welch, G.
- Affiliations
- Joslin Diabetes Center (US)
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 1999-05
- Volume
- 46
- Issue
- 5
- Pages
- 425-435
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W2171552218
- Cited by
- 141
- References
- 3
- Citations by year
- 2026: 1 · 2025: 2 · 2023: 1 · 2022: 5 · 2021: 1 · 2020: 2 · 2019: 8 · 2018: 5 · 2017: 4 · 2016: 7 · 2015: 3 · 2014: 9 · 2013: 7 · 2012: 2
- FWCI
- 3.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01am027845-05)
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK042315, DK42315-02)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- glycemic control, major depressive disorder, type 1 diabetes, type 2 diabetes, psychiatric comorbidity, HbA1c, diabetes treatment
- MeSH terms
- Adult, Aged, Analysis of Variance, Chronic Disease, Major Depressive Disorder, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Female, Glycated Hemoglobin, Humans, Hypoglycemic Agents, Male, Middle Aged, Patient Compliance
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