Phosphenes and transient scotomas induced by magnetic stimulation of the occipital lobe: their topographic relationship
Abstract
Transcranial magnetic stimulation (TMS) of the visual cortex is known to induce phosphenes and is able to suppress visual perception. To address the topographic relationship of phosphenes and transient scotomas, the visual field of 10 normal subjects was investigated using a perimetric approach. The central visual field (diameter: 20 degrees) was tested at 32 sites. Perceptual thresholds were determined by presenting 1 ms test spots flashed with varying intensity in random order. TMS was applied with a focal figure-of-eight coil placed over the inion. All subjects perceived phosphenes, mostly restricted to one of the lower quadrants within the visual field. In 13 out of 15 investigations, a magnetic stimulus triggered 100 ms after the visual target resulted in a relative scotoma with threshold changes of 8 dB or more. In 9 of 13 investigations, scotomas coincided spatially with sketches of phosphenes made by subjects in a separate test. Scotomas covered only a small percentage of the total visual field, which may explain the failure of previous studies to find perceptual suppression with the focal coil. The present result demonstrates that phosphenes evoked during TMS can serve as a guide for optimal visual stimulus alignment in neuropsychological experiments.
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Modeling and experimental work suggest that the spatial resolution of direct TMS stimulation is 5-10 mm.
“Modeling and experimental work suggest that the spatial resolution of direct TMS stimulation is 5–10 mm (11, 41).”
From Disruption of the right temporoparietal junction with transcranial magnetic stimulation reduces the role of beliefs in moral judgments (2010) · cites this paper as [41]
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- Authors
- Kammer, T.
- Affiliations
- Max Planck Society (DE)
- Corresponding author
- Kammer, Thomas
- ORCID
- Kammer, Thomas
- Venue
- Neuropsychologia
- Publisher
- Elsevier BV
- Published
- 1998-11
- Volume
- 37
- Issue
- 2
- Pages
- 191-198
- ISSN
- 0028-3932 (ISSN-L)
- OpenAlex
- W1494786883
- Cited by
- 170
- References
- 5
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 6 · 2021: 6 · 2020: 7 · 2019: 1 · 2018: 2 · 2017: 6 · 2016: 5 · 2015: 8 · 2014: 6 · 2013: 8 · 2012: 3
- FWCI
- 3.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropsychologia (publishedVersion)
- PubMed (publishedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Keywords
- phosphenes, transcranial magnetic stimulation, visual cortex, occipital lobe, visual field topography, perceptual suppression, visual perception, visual field testing
- MeSH terms
- Adult, Brain Mapping, Female, Humans, Magnetics, Male, Occipital Lobe, Phosphenes, Scotoma, Time Factors, Visual Fields
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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