Cited by 170Transcranial Magnetic Stimulation StudiesVisual perception and processing mechanismsTactile and Sensory Interactions

Phosphenes and transient scotomas induced by magnetic stimulation of the occipital lobe: their topographic relationship

Kammer, Thomas·1998·Neuropsychologia

Abstract

Transcranial magnetic stimulation (TMS) of the visual cortex is known to induce phosphenes and is able to suppress visual perception. To address the topographic relationship of phosphenes and transient scotomas, the visual field of 10 normal subjects was investigated using a perimetric approach. The central visual field (diameter: 20 degrees) was tested at 32 sites. Perceptual thresholds were determined by presenting 1 ms test spots flashed with varying intensity in random order. TMS was applied with a focal figure-of-eight coil placed over the inion. All subjects perceived phosphenes, mostly restricted to one of the lower quadrants within the visual field. In 13 out of 15 investigations, a magnetic stimulus triggered 100 ms after the visual target resulted in a relative scotoma with threshold changes of 8 dB or more. In 9 of 13 investigations, scotomas coincided spatially with sketches of phosphenes made by subjects in a separate test. Scotomas covered only a small percentage of the total visual field, which may explain the failure of previous studies to find perceptual suppression with the focal coil. The present result demonstrates that phosphenes evoked during TMS can serve as a guide for optimal visual stimulus alignment in neuropsychological experiments.

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Crossref · 10.1016/s0028-3932(98)00093-1

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Authors
Kammer, T.
Affiliations
Max Planck Society (DE)
Corresponding author
Kammer, Thomas
Venue
Neuropsychologia
Publisher
Elsevier BV
Published
1998-11
Volume
37
Issue
2
Pages
191-198
ISSN
0028-3932 (ISSN-L)
OpenAlex
W1494786883
Cited by
170
References
5
Citations by year
2026: 2 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 6 · 2021: 6 · 2020: 7 · 2019: 1 · 2018: 2 · 2017: 6 · 2016: 5 · 2015: 8 · 2014: 6 · 2013: 8 · 2012: 3
FWCI
3.03
Type
journal article
Language
en
Open access
closed
Locations
  • Neuropsychologia (publishedVersion)
  • PubMed (publishedVersion)
  • MPG.PuRe (Max Planck Society) (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
Keywords
phosphenes, transcranial magnetic stimulation, visual cortex, occipital lobe, visual field topography, perceptual suppression, visual perception, visual field testing
MeSH terms
Adult, Brain Mapping, Female, Humans, Magnetics, Male, Occipital Lobe, Phosphenes, Scotoma, Time Factors, Visual Fields

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