Cited by 343biodegradable polymer synthesis and propertiesPolymer crystallization and propertiesSurgical Sutures and Adhesives

Syntheses and application of polylactides

Kricheldorf, Hans R·2001·Chemosphere

Abstract

Polylactides can be prepared by direct polycondensation of lactic acid, or better, by ring-opening polymerization of cyclic dilactides (usually called lactides). These lactides exist in the form of four stereoisomers two of which (L,L- and rac. -D,L-) are technically produced in large quantities. These lactides can by polymerized via four different classes of initiators and reaction mechanisms. The characteristics mechanistic and preparative features of the cationic polymerization, anionic polymerization and of the coordination-insertion mechanism are described. Furthermore, copolymerizations of lactides with glycolide or epsilon-caprolactone and their analytical problems are discussed. Finally, a new type of wound dressing based on transparent are resorbable films of copolylactides is mentioned.

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Crossref · 10.1016/s0045-6535(00)00323-4

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Authors
Kricheldorf, H. R.
Affiliations
Universität Hamburg (DE)
Corresponding author
Kricheldorf, Hans R
Venue
Chemosphere
Publisher
Elsevier BV
Published
2001-04
Volume
43
Issue
1
Pages
49-54
ISSN
0045-6535 (ISSN-L)
OpenAlex
W1995595540
Cited by
343
References
25
Citations by year
2026: 2 · 2025: 9 · 2024: 5 · 2023: 9 · 2022: 9 · 2021: 17 · 2020: 8 · 2019: 11 · 2018: 9 · 2017: 16 · 2016: 15 · 2015: 12 · 2014: 18 · 2013: 23 · 2012: 26
FWCI
5.11
Type
journal article
Language
en
Open access
closed
Locations
  • Chemosphere (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
  • Physical Sciences › Materials Science › Polymers and Plastics › Polymer crystallization and properties
  • Health Sciences › Medicine › Surgery › Surgical Sutures and Adhesives
Keywords
polylactic acid, lactide ring-opening polymerization, stereoisomers, cationic polymerization, anionic polymerization, coordination-insertion mechanism, wound dressings, biodegradable polymers
MeSH terms
Bandages, Biocompatible Materials, Humans, Polyesters, Polymers

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