The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Lung Organogenesis
Open accessAbstract
Developmental lung biology is a field that has the potential for significant human impact: lung disease at the extremes of age continues to cause major morbidity and mortality worldwide. Understanding how the lung develops holds the promise that investigators can use this knowledge to aid lung repair and regeneration. In the decade since the “molecular embryology” of the lung was first comprehensively reviewed, new challenges have emerged—and it is on these that we focus the current review. Firstly, there is a critical need to understand the progenitor cell biology of the lung in order to exploit the potential of stem cells for the treatment of lung disease. Secondly, the current familiar descriptions of lung morphogenesis governed by growth and transcription factors need to be elaborated upon with the reinclusion and reconsideration of other factors, such as mechanics, in lung growth. Thirdly, efforts to parse the finer detail of lung bud signaling may need to be combined with broader consideration of overarching mechanisms that may be therapeutically easier to target: in this arena, we advance the proposal that looking at the lung in general (and branching in particular) in terms of clocks may yield unexpected benefits.
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Cites
Matrix elasticity directs stem cell lineage specification
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Identification of Novel Genes Coding for Small Expressed RNAs
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A decade of molecular biology of retinoic acid receptors
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“RA signaling is mediated by its nuclear receptors of the steroid hormone receptor superfamily: RAR (α, β, γ) and retinoid RXR (α, β, γ) (Chambon, 1996).”
BackgroundPDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis
Boström, H., Willetts, K., Pekny, M., Levéen, P., Lindahl, P., Hedstrand, H., Pekna, M., Hellström, M., Gebre-Medhin, S., Schalling, M., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81270-2 · Cited by 864
The Role of Hypoxia in Development of the Mammalian Embryo
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The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes
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Cited by
Song, H., Yao, E., Lin, C., Gacayan, R., Chen, M.-H., & Chuang, P.-T. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1207238109 · Cited by 311
Extracellular matrix in lung development, homeostasis and disease
Zhou, Y., Horowitz, J. C., Naba, A., Ambalavanan, N., Atabai, K., Balestrini, J., Bitterman, P. B., Corley, R. A., Ding, B.-S., Engler, A. J., et al. (2018) · Matrix Biology · doi:10.1016/j.matbio.2018.03.005 · Cited by 284
Sculpting Organs: Mechanical Regulation of Tissue Development
Nelson, C. M., & Gleghorn, J. P. (2012) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071811-150043 · Cited by 130
Age-driven developmental drift in the pathogenesis of idiopathic pulmonary fibrosis
Selman, M., López-Otín, C., & Pardo, A. (2016) · European Respiratory Journal · doi:10.1183/13993003.00398-2016 · Cited by 122
Varma, S., Cao, Y., Tagne, J.-B., Lakshminarayanan, M., Li, J., Friedman, T. B., Morell, R. J., Warburton, D., Kotton, D. N., & Ramirez, M. I. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.408401 · Cited by 79
Self-citation
Metadata
- Authors
- Warburton, D., El-Hashash, A., Carraro, G., Tiozzo, C., Sala, F., Rogers, O., Langhe, S. D., Kemp, P. J., Riccardi, D., Torday, J., Bellusci, S., Shi, W., Lubkin, S. R., & Jesudason, E.
- Venue
- Current Topics in Developmental Biology
- Publisher
- Elsevier
- Published
- 2010
- Volume
- 90
- Pages
- 73-158
- ISSN
- 0070-2153 (ISSN-L)
- OpenAlex
- W4211072041
- Cited by
- 421
- References
- 7
- FWCI
- 143.87
- Type
- book chapter
- Language
- en
- Open access
- green
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- Warburton, D., El-Hashash, A., Carraro, G., Tiozzo, C., Sala, F., Rogers, O., Langhe, S. D., Kemp, P. J., Riccardi, D., Torday, J., Bellusci, S., Shi, W., Lubkin, S. R., & Jesudason, E. (2010). Lung Organogenesis. Current Topics in Developmental Biology. https://doi.org/10.1016/s0070-2153(10)90003-3
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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