A connectome of a learning and memory center in the adult Drosophila brain
Open accessAbstract
Understanding memory formation, storage and retrieval requires knowledge of the underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of associative learning. We reconstructed the morphologies and synaptic connections of all 983 neurons within the three functional units, or compartments, that compose the adult MB’s α lobe, using a dataset of isotropic 8 nm voxels collected by focused ion-beam milling scanning electron microscopy. We found that Kenyon cells (KCs), whose sparse activity encodes sensory information, each make multiple en passant synapses to MB output neurons (MBONs) in each compartment. Some MBONs have inputs from all KCs, while others differentially sample sensory modalities. Only 6% of KC>MBON synapses receive a direct synapse from a dopaminergic neuron (DAN). We identified two unanticipated classes of synapses, KC>DAN and DAN>MBON. DAN activation produces a slow depolarization of the MBON in these DAN>MBON synapses and can weaken memory recall.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The MBs are known to be a centre for learning and memory in the fly brain.
“For example, the MBs are known to be a centre for learning and memory in the fly brain32.”
From Network statistics of the whole-brain connectome of Drosophila (2024) · cites this paper as [32]
The higher post-synapse counts in the hemibrain mushroom body lobes are explained by certain connections, especially KC-to-KC connections, being much more prevalent in the hemibrain than in FlyWire.
“This appears to be explained by certain connections (especially KC to KC connections, which are predominantly arranged with an unusual rosette configuration along axons and of which the functional significance is poorly understood121) being much more prevalent in the hemibrain than in FlyWire (Extended Data Fig. 7d).”
From Whole-brain annotation and multi-connectome cell typing of Drosophila (2024) · cites this paper as [121]
Previous dense reconstructions have demonstrated that existing catalogs of cell types are incomplete, even in well-covered regions.
“Previous dense reconstructions have demonstrated that existing catalogs of cell types are incomplete, even in well-covered regions (Takemura et al., 2017).”
From A connectome and analysis of the adult Drosophila central brain (2020) · cites this paper as Takemura et al., 2017
Previous EM reconstructions were either dense in much smaller volumes or sparse in larger volumes.
“Previous reconstructions were either dense in much smaller EM volumes (such as Meinertzhagen and O'Neil, 1991; Helmstaedter et al., 2013; Takemura et al., 2017) or sparse in larger volumes (such as Eichler et al., 2017 or Zheng et al., 2018).”
From A connectome and analysis of the adult Drosophila central brain (2020) · cites this paper as Takemura et al., 2017
Two previous connectomics efforts are available as well.
“Two previous connectomics efforts are available as well (a seven-column optic lobe reconstruction [Takemura et al., 2015] and the alpha lobe of the mushroom body [Takemura et al., 2017]).”
From A connectome and analysis of the adult Drosophila central brain (2020) · cites this paper as Takemura et al., 2017
The least tightly bound large motif is a cell that connects either to or from (but not both) all cells of a given type; this motif is very common, with more than 500 examples in the fly's brain.
“The least tightly bound large motif is a cell that connects either to or from (but not both) all cells of a given type, as shown in Figure 22(c). Examples include the mushroom body output neurons (Takemura et al., 2017). This is a very common motif, found in many regions. We find more than 500 examples of this in the fly’s brain.”
From A connectome and analysis of the adult Drosophila central brain (2020) · cites this paper as Takemura et al., 2017
Broadcasters include a large number of Mi1 and Tm3 neurons-excitatory cells in the ME known to have key roles in the motion detection circuit.
“Broadcasters include a large number of Mi1 and Tm3 neurons—excitatory cells in the ME known to have key roles in the motion detection circuit32,40.”
From Network statistics of the whole-brain connectome of Drosophila (2024) · cites this paper as [32]
The Introduction (Figure 1) and Results (Cell type identification) describe mushroom-body circuits, not medulla motion-detection neurons. Searches for Mi1, Tm3, broadcasters, and the motion-detection circuit found no passage in our copy addressing the attributed claim. (LLM, conf=0.78)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Fiji: an open-source platform for biological-image analysis
Schindelin, J., Arganda-Carreras, I., Frise, E., Kaynig, V., Longair, M., Pietzsch, T., Preibisch, S., Rueden, C., Saalfeld, S., Schmid, B., et al. (2012) · Nature Methods · doi:10.1038/nmeth.2019 · Cited by 66,890 · see citing works
Lecture Notes in Computer Science 1205
(1999) · Industrial Robot the international journal of robotics research and application · doi:10.1108/ir.1999.04926fae.001 · Cited by 39,228 · see citing works
Rescorla, R. A. (1972) · Medical Entomology and Zoology · Cited by 7,268 · see citing works
Predictive reward signal of dopamine neurons
Schultz, W. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.1.1 · Cited by 4,564 · see citing works
Independent optical excitation of distinct neural populations
Klapoetke, N. C., Murata, Y., Kim, S. S., Pulver, S. R., Birdsey-Benson, A., Cho, Y. K., Morimoto, T. K., Chuong, A. S., Carpenter, E. J., Tian, Z., et al. (2014) · Nature Methods · doi:10.1038/nmeth.2836 · Cited by 2,344 · see citing works
Neuronal circuits for fear and anxiety
Tovote, P., Fadok, J. P., & Lüthi, A. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3945 · Cited by 1,786 · see citing works
Molecular Biology of Learning: Modulation of Transmitter Release
Kandel, E. R., & Schwartz, J. H. (1982) · Science · doi:10.1126/science.6289442 · Cited by 1,551 · see citing works
Spatiotemporal Rescue of Memory Dysfunction in Drosophila
McGuire, S. E., Le, P. T., Osborn, A. J., Matsumoto, K., & Davis, R. L. (2003) · Science · doi:10.1126/science.1089035 · Cited by 1,318 · see citing works
Mushroom body memoir: from maps to models
Heisenberg, M. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1074 · Cited by 1,286 · see citing works
Classical conditioning and retention in normal and mutantDrosophila melanogaster
Tully, T., & Quinn, W. G. (1985) · Journal of Comparative Physiology A · doi:10.1007/bf01350033 · Cited by 1,189 · see citing works
Strausfeld, N. (1976) · Springer Berlin Heidelberg · doi:10.1007/978-3-642-66179-2 · Cited by 1,178 · see citing works
The neuronal architecture of the mushroom body provides a logic for associative learning
Aso, Y., Hattori, D., Yu, Y., Johnston, R. M., Iyer, N. A., Ngo, T.-T., Dionne, H., Abbott, L., Axel, R., Tanimoto, H., et al. (2014) · eLife · doi:10.7554/elife.04577 · Cited by 1,051 · see citing works
Self-citationStrausfeld, N. J. (1976) · Medical Entomology and Zoology · Cited by 967 · see citing works
Schwaerzel, M., Monastirioti, M., Scholz, H., Friggi-Grelin, F., Birman, S., & Heisenberg, M. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-33-10495.2003 · Cited by 871 · see citing works
Associative Odor Learning in Drosophila Abolished by Chemical Ablation of Mushroom Bodies
de Belle, J. S., & Heisenberg, M. (1994) · Science · doi:10.1126/science.8303280 · Cited by 797 · see citing works
Oscillations and Sparsening of Odor Representations in the Mushroom Body
Pérez-Orive, J., Mazor, O., Turner, G. C., Cassenaer, S., Wilson, R. I., & Laurent, G. (2002) · Science · doi:10.1126/science.1070502 · Cited by 792 · see citing works
Self-citationIto, K., Awano, W., Suzuki, K., Hiromi, Y., & Yamamoto, D. (1997) · Development · doi:10.1242/dev.124.4.761 · Cited by 757 · see citing works
Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila
Aso, Y., Sitaraman, D., Ichinose, T., Kaun, K. R., Vogt, K., Belliart-Guérin, G., Plaçais, P.-Y., Robie, A. A., Yamagata, N., Schnaitmann, C., et al. (2014) · eLife · doi:10.7554/elife.04580 · Cited by 707 · see citing works
Self-citationDrosophila Mushroom Body Mutants are Deficient in Olfactory Learning
Heisenberg, M., Borst, A., Wagner, S., & Byers, D. (1985) · Journal of Neurogenetics · doi:10.3109/01677068509100140 · Cited by 697 · see citing works
A visual motion detection circuit suggested by Drosophila connectomics
Takemura, S.-Y., Bharioke, A., Lu, Z., Nern, A., Vitaladevuni, S., Rivlin, P. K., Katz, W. T., Olbris, D. J., Plaza, S. M., Winston, P., et al. (2013) · Nature · doi:10.1038/nature12450 · Cited by 686 · see citing works
Self-citationA subset of dopamine neurons signals reward for odour memory in Drosophila
Liu, C., Plaçais, P.-Y., Yamagata, N., Pfeiffer, B. D., Aso, Y., Friedrich, A. B., Siwanowicz, I., Rubin, G. M., Préat, T., & Tanimoto, H. (2012) · Nature · doi:10.1038/nature11304 · Cited by 623 · see citing works
Self-citationLayered reward signalling through octopamine and dopamine in Drosophila
Burke, C. J., Huetteroth, W., Owald, D., Perisse, E., Krashes, M. J., Das, G., Gohl, D., Silies, M., Certel, S., & Waddell, S. (2012) · Nature · doi:10.1038/nature11614 · Cited by 614 · see citing works
Localization of a Short-Term Memory in Drosophila
Zars, T. D., Fischer, M., Schulz, R. A., & Heisenberg, M. (2000) · Science · doi:10.1126/science.288.5466.672 · Cited by 600 · see citing works
A Neural Circuit Mechanism Integrating Motivational State with Memory Expression in Drosophila
Krashes, M. J., DasGupta, S., Vreede, A., White, B., Armstrong, J. D., & Waddell, S. (2009) · Cell · doi:10.1016/j.cell.2009.08.035 · Cited by 598 · see citing works
A mathematical model for simple learning.
Bush, R. R., & Mosteller, F. C. (1951) · Psychological Review · doi:10.1037/h0054388 · Cited by 590 · see citing works
Schroll, C., Riemensperger, T. D., Bucher, D. B., Ehmer, J., Völler, T., Erbguth, K., Gerber, B., Hendel, T., Nagel, G., Buchner, E., et al. (2006) · Current Biology · doi:10.1016/j.cub.2006.07.023 · Cited by 587 · see citing works
Livingstone, M. S., Sziber, P. P., & Quinn, W. G. (1984) · Cell · doi:10.1016/0092-8674(84)90316-7 · Cited by 587 · see citing works
Spatial Representation of the Glomerular Map in the Drosophila Protocerebrum
Wong, A. M., Wang, J. W., & Axel, R. (2002) · Cell · doi:10.1016/s0092-8674(02)00707-9 · Cited by 560 · see citing works
Self-citationCardin, J. A., Carlén, M., Meletis, K., Knoblich, U., Zhang, F., Deisseroth, K. A., Tsai, L., & Moore, C. I. (2010) · Nature Protocols · doi:10.1038/nprot.2009.228 · Cited by 542 · see citing works
Mao, Z. (2009) · Frontiers in Neural Circuits · doi:10.3389/neuro.04.005.2009 · Cited by 532 · see citing works
Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate
Stuber, G. D., Hnasko, T. S., Britt, J. P., Edwards, R. H., & Bonci, A. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1754-10.2010 · Cited by 529 · see citing works
The Drosophila learning and memory gene rutabaga encodes a - adenylyl cyclase
Levin, L. R., Han, P.-L., Hwang, P. M., Feinstein, P. G., Davis, R. L., & Reed, R. R. (1992) · Cell · doi:10.1016/0092-8674(92)90185-f · Cited by 517 · see citing works
Writing Memories with Light-Addressable Reinforcement Circuitry
Claridge-Chang, A., Roorda, R. D., Vrontou, E., Sjulson, L., Li, H., Hirsh, J., & Miesenböck, G. (2009) · Cell · doi:10.1016/j.cell.2009.08.034 · Cited by 484 · see citing works
Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain
Garris, P. A., Ciolkowski, E. L., Pastore, P., & Wightman, R. M. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-10-06084.1994 · Cited by 475 · see citing works
Neuronal assemblies of the <i>Drosophila</i> mushroom body
Tanaka, N. K., Tanimoto, H., & Ito, K. (2008) · Journal of Comparative Neurology · doi:10.1002/cne.21692 · Cited by 470 · see citing works
The Role of Drosophila Mushroom Body Signaling in Olfactory Memory
McGuire, S. E., Le, P. T., & Davis, R. L. (2001) · Science · doi:10.1126/science.1062622 · Cited by 457 · see citing works
Neuronal architecture of the antennal lobe in Drosophila melanogaster
Stocker, R. F., Lienhard, M. C., Borst, A., & Fischbach, K. F. (1990) · Cell and Tissue Research · doi:10.1007/bf00327741 · Cited by 457 · see citing works
Schmitz, D., Schuchmann, S., Fisahn, A., Draguhn, A., Buhl, E. H., Petrasch‐Parwez, E., Dermietzel, R., Heinemann, U., & Traub, R. D. (2001) · Neuron · doi:10.1016/s0896-6273(01)00410-x · Cited by 456 · see citing works
Dubnau, J., Grady, L., Kitamoto, T., & Tully, T. (2001) · Nature · doi:10.1038/35078077 · Cited by 455 · see citing works
Tripartite Mushroom Body Architecture Revealed by Antigenic MarkersPreprint
Crittenden, J. R., Skoulakis, E. M. C., Han, K., Kalderon, D., & Davis, R. L. (1998) · Learning & Memory · doi:10.1101/lm.5.1.38 · Cited by 446 · see citing works
Coordinated and compartmentalized neuromodulation shapes sensory processing in Drosophila
Cohn, R., Morantte, I., & Ruta, V. (2015) · Cell · doi:10.1016/j.cell.2015.11.019 · Cited by 430 · see citing works
Olfactory Representations by Drosophila Mushroom Body Neurons
Turner, G. C., Bazhenov, M., & Laurent, G. (2007) · Journal of Neurophysiology · doi:10.1152/jn.01283.2007 · Cited by 416 · see citing works
Self-citationLocalization of short‐term memory in the brain of the bee, Apis mellifera
Erber, J., Masuhr, T., & Menzel, R. (1980) · Physiological Entomology · doi:10.1111/j.1365-3032.1980.tb00244.x · Cited by 412 · see citing works
Enhanced FIB-SEM systems for large-volume 3D imaging
Xu, C. S., Hayworth, K. J., Lu, Z., Grob, P., Hassan, A. M., García-Cerdán, J. G., Niyogi, K. K., Nogales, E., Weinberg, R. J., & Hess, H. F. (2017) · eLife · doi:10.7554/elife.25916 · Cited by 411 · see citing works
Self-citationRandom convergence of olfactory inputs in the Drosophila mushroom body
Caron, S. J. C., Ruta, V., Abbott, L. F., & Axel, R. (2013) · Nature · doi:10.1038/nature12063 · Cited by 409 · cited 1× · see citing works
“…projection neurons of olfactory and other modalities including visual, gustatory and thermal (Vogt et al., 2016; Kirkhart and Scott, 2015; Yagi et al., 2016; Caron et al., 2013; Stocker et al., 1990; Wong et al., 2002; Strausfeld, 1976; Tanaka et al., 2004; Liu et al., 2015; Frank et al., 2015).”
BackgroundThe cerebellar microcircuit as an adaptive filter: experimental and computational evidence
Dean, P., Porrill, J., Ekerot, C. ‐., & Jörntell, H. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2756 · Cited by 395 · see citing works
The Mushroom Body of Adult Drosophila Characterized by GAL4 Drivers
Aso, Y., Grübel, K., Busch, S., Friedrich, A. B., Siwanowicz, I., & Tanimoto, H. (2009) · Journal of Neurogenetics · doi:10.1080/01677060802471718 · Cited by 381 · see citing works
Self-citationLocalization of Long-Term Memory Within the Drosophila Mushroom Body
Pascual, A., & Préat, T. (2001) · Science · doi:10.1126/science.1064200 · Cited by 368 · see citing works
Activity of Defined Mushroom Body Output Neurons Underlies Learned Olfactory Behavior in Drosophila
Owald, D., Felsenberg, J., Talbot, C. B., Das, G., Perisse, E., Huetteroth, W., & Waddell, S. (2015) · Neuron · doi:10.1016/j.neuron.2015.03.025 · Cited by 367 · see citing works
Kim, Y.-C., Lee, H.-G., & Han, K. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1167-07.2007 · Cited by 365 · see citing works
Heterosynaptic plasticity underlies aversive olfactory learning in Drosophila
Hige, T., Aso, Y., Modi, M. N., Rubin, G. M., & Turner, G. C. (2015) · Neuron · doi:10.1016/j.neuron.2015.11.003 · Cited by 354 · see citing works
Punishment Prediction by Dopaminergic Neurons in Drosophila
Riemensperger, T. D., Völler, T., Stock, P., Buchner, E., & Fiala, A. (2005) · Current Biology · doi:10.1016/j.cub.2005.09.042 · Cited by 350 · see citing works
Ito, K., Suzuki, K., Estes, P. S., Ramaswami, M., Yamamoto, D., & Strausfeld, N. J. (1998) · Learning & Memory · doi:10.1101/lm.5.1.52 · Cited by 337 · see citing works
Waddell, S., Armstrong, J. D., Kitamoto, T., Kaiser, K., & Quinn, W. G. (2000) · Cell · doi:10.1016/s0092-8674(00)00183-5 · Cited by 332 · see citing works
Specific Dopaminergic Neurons for the Formation of Labile Aversive Memory
Aso, Y., Siwanowicz, I., Bräcker, L. B., Ito, K., Kitamoto, T., & Tanimoto, H. (2010) · Current Biology · doi:10.1016/j.cub.2010.06.048 · Cited by 324 · see citing works
Self-citationAn elegant mind: Learning and memory in <i>Caenorhabditis elegans</i>
Ardiel, E. L., & Rankin, C. H. (2010) · Learning & Memory · doi:10.1101/lm.960510 · Cited by 323 · see citing works
Three Dopamine Pathways Induce Aversive Odor Memories with Different Stability
Aso, Y., Herb, A., Ogueta, M., Siwanowicz, I., Templier, T., Friedrich, A. B., Ito, K., Scholz, H., & Tanimoto, H. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002768 · Cited by 320 · see citing works
Self-citationSparse, decorrelated odor coding in the mushroom body enhances learned odor discrimination
Lin, A. C., Bygrave, A. M., de Calignon, A., Lee, T., & Miesenböck, G. (2014) · Nature Neuroscience · doi:10.1038/nn.3660 · Cited by 317 · see citing works
Dopaminergic neurons write and update memories with cell-type-specific rules
Aso, Y., & Rubin, G. M. (2016) · eLife · doi:10.7554/elife.16135 · Cited by 306 · see citing works
Self-citationGonon, F. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-15-05972.1997 · Cited by 301 · see citing works
A Neural Computational Model of Incentive Salience
Zhang, J., Berridge, K. C., Tindell, A. J., Smith, K. S., & Aldridge, J. W. (2009) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000437 · Cited by 299 · see citing works
Krashes, M. J., & Waddell, S. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5333-07.2008 · Cited by 297 · see citing works
The glia of the adult D rosophila nervous system
Kremer, M. C., Jung, C., Batelli, S., Rubin, G. M., & Gaul, U. (2017) · Glia · doi:10.1002/glia.23115 · Cited by 297 · see citing works
Self-citationDopamine Is Required for Learning and Forgetting in Drosophila
Berry, J. A., Cervantes-Sandoval, I., Nicholas, E. P., & Davis, R. L. (2012) · Neuron · doi:10.1016/j.neuron.2012.04.007 · Cited by 296 · see citing works
DAMB, a Novel Dopamine Receptor Expressed Specifically in Drosophila Mushroom Bodies
Han, K., Millar, N. S., Grotewiel, M. S., & Davis, R. L. (1996) · Neuron · doi:10.1016/s0896-6273(00)80139-7 · Cited by 290 · see citing works
Distinct dopamine neurons mediate reward signals for short- and long-term memories
Yamagata, N., Ichinose, T., Aso, Y., Plaçais, P.-Y., Friedrich, A. B., Sima, R., Préat, T., Rubin, G. M., & Tanimoto, H. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1421930112 · Cited by 288 · see citing works
Self-citationReinforcement signalling in Drosophila; dopamine does it all after all
Waddell, S. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.01.005 · Cited by 287 · see citing works
Mushroom bodies of the cockroach: Their participation in place memory
Mizunami, M., Weibrecht, J. M., & Strausfeld, N. J. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19981228)402:4 · Cited by 284 · see citing works
Integration of Chemosensory Pathways in the Drosophila Second-Order Olfactory Centers
Tanaka, N. K., Awasaki, T., Shimada, T., & Ito, K. (2004) · Current Biology · doi:10.1016/j.cub.2004.03.006 · Cited by 280 · see citing works
Yu, D., Akalal, D.-B. G., & Davis, R. L. (2006) · Neuron · doi:10.1016/j.neuron.2006.10.030 · Cited by 266 · see citing works
Sweet Taste and Nutrient Value Subdivide Rewarding Dopaminergic Neurons in Drosophila
Huetteroth, W., Perisse, E., Lin, S., Klappenbach, M., Burke, C., & Waddell, S. (2015) · Current Biology · doi:10.1016/j.cub.2015.01.036 · Cited by 265 · see citing works
Parallels between cerebellum- and amygdala-dependent conditioning
Medina, J. F., Repa, J. C., Mauk, M. D., & LeDoux, J. E. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn728 · Cited by 265 · see citing works
Mushroom body efferent neurons responsible for aversive olfactory memory retrieval in Drosophila
Séjourné, J., Plaçais, P.-Y., Aso, Y., Siwanowicz, I., Trannoy, S., Thoma, V., Tedjakumala, S. R., Rubin, G. M., Tchénio, P., Ito, K., et al. (2011) · Nature Neuroscience · doi:10.1038/nn.2846 · Cited by 265 · see citing works
Self-citationTakemura, S.-Y., Xu, C. S., Lu, Z., Rivlin, P. K., Parag, T., Olbris, D. J., Plaza, S., Zhao, T., Katz, W. T., Umayam, L., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1509820112 · Cited by 264 · see citing works
Self-citationCellular-Resolution Population Imaging Reveals Robust Sparse Coding in the Drosophila Mushroom Body
Honegger, K. S., Campbell, R. A. A., & Turner, G. C. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1099-11.2011 · Cited by 250 · see citing works
Self-citationThe GABAergic anterior paired lateral neuron suppresses and is suppressed by olfactory learning
Liu, X., & Davis, R. L. (2009) · Nature Neuroscience · doi:10.1038/nn.2235 · Cited by 250 · see citing works
Sleep Facilitates Memory by Blocking Dopamine Neuron-Mediated Forgetting
Berry, J. A., Cervantes-Sandoval, I., Chakraborty, M., & Davis, R. L. (2015) · Cell · doi:10.1016/j.cell.2015.05.027 · Cited by 244 · see citing works
Technau, G. M. (1984) · Journal of Neurogenetics · doi:10.3109/01677068409107077 · Cited by 241 · see citing works
A Drosophila model for alcohol reward
Kaun, K. R., Azanchi, R., Maung, Z., Hirsh, J., & Heberlein, U. (2011) · Nature Neuroscience · doi:10.1038/nn.2805 · Cited by 234 · see citing works
Gervasi, N., Tchénio, P., & Préat, T. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.014 · Cited by 230 · see citing works
A Map of Olfactory Representation in the Drosophila Mushroom Body
Lin, H., Lai, J. S.-Y., Chin, A., Chen, Y., & Chiang, A. (2007) · Cell · doi:10.1016/j.cell.2007.03.006 · Cited by 224 · see citing works
Thirty years of olfactory learning and memory research in Drosophila melanogaster
McGuire, S. E., Deshazer, M., & Davis, R. L. (2005) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.09.003 · Cited by 220 · see citing works
Tomchik, S. M., & Davis, R. L. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.029 · Cited by 217 · see citing works
Perisse, E., Owald, D., Barnstedt, O., Talbot, C. B., Huetteroth, W., & Waddell, S. (2016) · Neuron · doi:10.1016/j.neuron.2016.04.034 · Cited by 216 · see citing works
Conditional modulation of spike-timing-dependent plasticity for olfactory learning
Cassenaer, S., & Laurent, G. (2012) · Nature · doi:10.1038/nature10776 · Cited by 215 · see citing works
Normalization for Sparse Encoding of Odors by a Wide-Field Interneuron
Papadopoulou, M., Cassenaer, S., Nowotny, T., & Laurent, G. (2011) · Science · doi:10.1126/science.1201835 · Cited by 214 · see citing works
Neural correlates of water reward in thirsty Drosophila
Lin, S., Owald, D., Chandra, V., Talbot, C. B., Huetteroth, W., & Waddell, S. (2014) · Nature Neuroscience · doi:10.1038/nn.3827 · Cited by 213 · see citing works
Gamma Neurons Mediate Dopaminergic Input during Aversive Olfactory Memory Formation in Drosophila
Qin, H., Cressy, M., Li, W., Coravos, J. S., Izzi, S. A., & Dubnau, J. (2012) · Current Biology · doi:10.1016/j.cub.2012.02.014 · Cited by 205 · see citing works
Short- and Long-Term Memory in Drosophila Require cAMP Signaling in Distinct Neuron Types
Blum, A. L., Li, W., Cressy, M., & Dubnau, J. (2009) · Current Biology · doi:10.1016/j.cub.2009.07.016 · Cited by 200 · see citing works
Synaptic circuits of the <i>Drosophila</i> optic lobe: The input terminals to the medulla
Takemura, S., Lu, Z., & Meinertzhagen, I. A. (2008) · Journal of Comparative Neurology · doi:10.1002/cne.21757 · Cited by 199 · see citing works
Self-citationMemory-Relevant Mushroom Body Output Synapses Are Cholinergic
Barnstedt, O., Owald, D., Felsenberg, J., Brain, R., Moszynski, J.-P., Talbot, C. B., Perrat, P. N., & Waddell, S. (2016) · Neuron · doi:10.1016/j.neuron.2016.02.015 · Cited by 197 · see citing works
A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster
Haynes, P. R., Christmann, B. L., & Griffith, L. C. (2015) · eLife · doi:10.7554/elife.03868 · Cited by 186 · see citing works
Temperature representation in the Drosophila brain
Frank, D. D., Jouandet, G. C., Kearney, P. J., Macpherson, L. J., & Gallio, M. (2015) · Nature · doi:10.1038/nature14284 · Cited by 178 · see citing works
Bouzaiane, E., Trannoy, S., Scheunemann, L., Plaçais, P.-Y., & Préat, T. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.04.044 · Cited by 175 · see citing works
Yu, D., Keene, A. C., Srivatsan, A., Waddell, S., & Davis, R. L. (2005) · Cell · doi:10.1016/j.cell.2005.09.037 · Cited by 167 · see citing works
Testing Odor Response Stereotypy in the Drosophila Mushroom Body
Murthy, M., Fiete, I., & Laurent, G. (2008) · Neuron · doi:10.1016/j.neuron.2008.07.040 · Cited by 163 · see citing works
Reward signal in a recurrent circuit drives appetitive long-term memory formation
Ichinose, T., Aso, Y., Yamagata, N., Abe, A., Rubin, G. M., & Tanimoto, H. (2015) · eLife · doi:10.7554/elife.10719 · Cited by 162 · see citing works
Self-citationA Higher Brain Circuit for Immediate Integration of Conflicting Sensory Information in Drosophila
Lewis, L., Siju, K. P., Aso, Y., Friedrich, A. B., Bulteel, A. J. B., Rubin, G. M., & Kadow, I. C. G. (2015) · Current Biology · doi:10.1016/j.cub.2015.07.015 · Cited by 161 · see citing works
Self-citationTraub, R. D., Pais, I. P., Bibbig, A., LeBeau, F. E. N., Buhl, E. H., Hormuzdi, S. G., Monyer, H., & Whittington, M. A. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337529100 · Cited by 159 · see citing works
Plasticity-driven individualization of olfactory coding in mushroom body output neurons
Hige, T., Aso, Y., Rubin, G. M., & Turner, G. C. (2015) · Nature · doi:10.1038/nature15396 · Cited by 157 · see citing works
Self-citationDopamine neurons encoding long-term memory of object value for habitual behavior
Kim, H. F., Ghazizadeh, A., & Hikosaka, O. (2015) · Cell · doi:10.1016/j.cell.2015.10.063 · Cited by 157 · see citing works
Strausfeld, N. J., Sinakevitch, I. G., & Vilinsky, I. (2003) · Microscopy Research and Technique · doi:10.1002/jemt.10368 · Cited by 155 · see citing works
Direct neural pathways convey distinct visual information to Drosophila mushroom bodies
Vogt, K., Aso, Y., Hige, T., Knapek, S., Ichinose, T., Friedrich, A. B., Turner, G. C., Rubin, G. M., & Tanimoto, H. (2016) · eLife · doi:10.7554/elife.14009 · Cited by 155 · see citing works
Self-citationIntegration of the olfactory code across dendritic claws of single mushroom body neurons
Gruntman, E., & Turner, G. C. (2013) · Nature Neuroscience · doi:10.1038/nn.3547 · Cited by 151 · see citing works
Self-citationGustatory Learning and Processing in the Drosophila Mushroom Bodies
Kirkhart, C. R., & Scott, K. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.3930-14.2015 · Cited by 150 · see citing works
Dopamine D1-Like Receptor Activation Excites Rat Striatal Large Aspiny NeuronsIn Vitro
Aosaki, T., Kiuchi, K., & Kawaguchi, Y. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-14-05180.1998 · Cited by 149 · see citing works
Diverse Odor-Conditioned Memories Require Uniquely Timed Dorsal Paired Medial Neuron Output
Keene, A. C., Stratmann, M., Keller, A., Perrat, P. N., Vosshall, L. B., & Waddell, S. (2004) · Neuron · doi:10.1016/j.neuron.2004.10.006 · Cited by 149 · see citing works
Lee, P.-T., Lin, H.-W., Chang, Y. A., Fu, T., Dubnau, J., Hirsh, J., Lee, T., & Chiang, A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019483108 · Cited by 147 · see citing works
Parallel Processing of Appetitive Short- and Long-Term Memories In Drosophila
Trannoy, S., Redt‐Clouet, C., Dura, J., & Préat, T. (2011) · Current Biology · doi:10.1016/j.cub.2011.08.032 · Cited by 147 · see citing works
A Pair of Inhibitory Neurons Are Required to Sustain Labile Memory in the Drosophila Mushroom Body
Pitman, J. L., Huetteroth, W., Burke, C. J., Krashes, M. J., Lai, S.-L., Lee, T., & Waddell, S. (2011) · Current Biology · doi:10.1016/j.cub.2011.03.069 · Cited by 137 · see citing works
Drosophila Dorsal Paired Medial Neurons Provide a General Mechanism for Memory Consolidation
Keene, A. C., Krashes, M. J., Leung, B., Bernard, J. A., & Waddell, S. (2006) · Current Biology · doi:10.1016/j.cub.2006.06.022 · Cited by 137 · see citing works
Imaging a Population Code for Odor Identity in the Drosophila Mushroom Body
Campbell, R. A. A., Honegger, K. S., Qin, H., Li, W., Demir, E., & Turner, G. C. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0682-12.2013 · Cited by 129 · see citing works
Self-citationDifferent Kenyon Cell Populations Drive Learned Approach and Avoidance in Drosophila
Perisse, E., Yin, Y., Lin, A. C., Lin, S., Huetteroth, W., & Waddell, S. (2013) · Neuron · doi:10.1016/j.neuron.2013.07.045 · Cited by 127 · see citing works
Kim, Y.-C., Lee, H.-G., Seong, C.-S., & Han, K. (2003) · Gene Expression Patterns · doi:10.1016/s1567-133x(02)00098-4 · Cited by 125 · see citing works
Pai, T.-P., Chen, C.-C., Lin, H., Chin, A., Lai, J. S.-Y., Lee, P.-T., Tully, T., & Chiang, A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1216336110 · Cited by 118 · see citing works
Bemerkungen zur funktion der corpora pedunculata im gehirn der insekten aus morphologischer sicht
Sch�rmann, F. W. (1974) · Experimental Brain Research · doi:10.1007/bf00234464 · Cited by 114 · see citing works
An Ultra-Short Dopamine Pathway Regulates Basal Ganglia Output
Zhou, F., Jin, Y. H., Matta, S. G., Xu, M., & Zhou, F.-M. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4402-08.2009 · Cited by 114 · see citing works
Four Individually Identified Paired Dopamine Neurons Signal Reward in Larval Drosophila
Rohwedder, A., Wenz, N. L., Stehle, B., Huser, A., Yamagata, N., Zlatic, M., Truman, J. W., Tanimoto, H., Saumweber, T., Gerber, B., et al. (2016) · Current Biology · doi:10.1016/j.cub.2016.01.012 · Cited by 114 · see citing works
Heterotypic Gap Junctions between Two Neurons in the Drosophila Brain Are Critical for Memory
Wu, C., Shih, M.-F. M., Lai, J. S.-Y., Yang, H.-T., Turner, G. C., Chen, L., & Chiang, A. (2011) · Current Biology · doi:10.1016/j.cub.2011.02.041 · Cited by 112 · see citing works
Self-citationCrocker, A., Guan, X.-J., Murphy, C. T., & Murthy, M. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.04.046 · Cited by 108 · see citing works
Boto, T., Louis, T., Jindachomthong, K., Jalink, K., & Tomchik, S. M. (2014) · Current Biology · doi:10.1016/j.cub.2014.03.021 · Cited by 107 · see citing works
Control of Sleep by Dopaminergic Inputs to the Drosophila Mushroom Body
Sitaraman, D., Aso, Y., Rubin, G. M., & Nitabach, M. N. (2015) · Frontiers in Neural Circuits · doi:10.3389/fncir.2015.00073 · Cited by 107 · see citing works
Self-citationSIFamide is a highly conserved neuropeptide: a comparative study in different insect species
Verleyen, P., Huybrechts, J., Baggerman, G., Lommel, A. V., LOOF, A. D., & Schoofs, L. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.05.173 · Cited by 103 · see citing works
Drosophila Learn Opposing Components of a Compound Food Stimulus
Das, G., Klappenbach, M., Vrontou, E., Perisse, E., Clark, C. M., Burke, C. J., & Waddell, S. (2014) · Current Biology · doi:10.1016/j.cub.2014.05.078 · Cited by 102 · see citing works
Thermosensory processing in the Drosophila brain
Liu, W. W., Mazor, O., & Wilson, R. I. (2015) · Nature · doi:10.1038/nature14170 · Cited by 102 · see citing works
Cervantes-Sandoval, I., Phan, A., Chakraborty, M., & Davis, R. L. (2017) · eLife · doi:10.7554/elife.23789 · Cited by 96 · see citing works
Delayed Dopamine Signaling of Energy Level Builds Appetitive Long-Term Memory in Drosophila
Musso, P., Tchénio, P., & Préat, T. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.01.036 · Cited by 92 · see citing works
SIFamide and SIFamide Receptor Define a Novel Neuropeptide Signaling to Promote Sleep in Drosophila
Park, S., Sonn, J. Y., Oh, Y., Lim, C., & Choe, J. (2014) · Molecules and Cells · doi:10.14348/molcells.2014.2371 · Cited by 90 · see citing works
Evolutionary progression at synaptic connections made by identified homologous neurones.
Shaw, S. R., & Meinertzhagen, I. A. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.20.7961 · Cited by 88 · see citing works
Schleyer, M. H., Saumweber, T., Nahrendorf, W., Fischer, B., von Alpen, D. C., Pauls, D., Thum, A. S., & Gerber, B. (2011) · Learning & Memory · doi:10.1101/lm.2163411 · Cited by 81 · see citing works
Convergence of multimodal sensory pathways to the mushroom body calyx in Drosophila melanogaster
Yagi, R., Mabuchi, Y., Mizunami, M., & Tanaka, N. K. (2016) · Scientific Reports · doi:10.1038/srep29481 · Cited by 80 · see citing works
Pech, U., Pooryasin, A., Birman, S., & Fiala, A. (2013) · The Journal of Comparative Neurology · doi:10.1002/cne.23388 · Cited by 79 · see citing works
Toward large-scale connectome reconstructions
Plaza, S. M., Scheffer, L. K., & Chklovskii, D. B. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.01.019 · Cited by 78 · see citing works
Self-citationMarder, E., Gutierrez, G. J., & Nusbaum, M. P. (2017) · Developmental Neurobiology · doi:10.1002/dneu.22410 · Cited by 73 · see citing works
Learning the specific quality of taste reinforcement in larval Drosophila
Schleyer, M. H., Miura, D., Tanimura, T., & Gerber, B. (2015) · eLife · doi:10.7554/elife.04711 · Cited by 70 · see citing works
Gap junction networks in mushroom bodies participate in visual learning and memory in Drosophila
Liu, Q., Yang, X., Tian, J., Gao, Z., Wang, M., Li, Y., & Guo, A. (2016) · eLife · doi:10.7554/elife.13238 · Cited by 60 · see citing works
Akalal, D.-B. G., Yu, D., & Davis, R. L. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.3190-10.2011 · Cited by 59 · see citing works
Distinct Traces for Appetitive versus Aversive Olfactory Memories in DPM Neurons of Drosophila
Cervantes-Sandoval, I., & Davis, R. L. (2012) · Current Biology · doi:10.1016/j.cub.2012.05.009 · Cited by 50 · see citing works
A Subset of Cholinergic Mushroom Body Neurons Requires Go Signaling to Regulate Sleep in Drosophila
Yi, W., Zhang, Y., Tian, Y., Guo, J., Li, Y., & Guo, A. (2013) · SLEEP · doi:10.5665/sleep.3206 · Cited by 48 · see citing works
Mancini, G., & Frontali, N. (1970) · Cell and Tissue Research · doi:10.1007/bf00335278 · Cited by 47 · see citing works
Deep and Wide Multiscale Recursive Networks for Robust Image LabelingPreprint
Huang, G. B., & Jain, V. (2013) · International Conference on Learning Representations · doi:10.48550/arxiv.1310.0354 · Cited by 45 · see citing works
Self-citationThompson, S. M., Fortunato, C., McKinney, R. A., M�ller, M., & G�hwiler, B. H. (1996) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19960902)372:4 · Cited by 45 · see citing works
Fine structure of the mushroom body neuropile of the brain of the roach, Periplaneta americana
Mancini, G., & Frontali, N. (1967) · Cell and Tissue Research · doi:10.1007/bf00336862 · Cited by 41 · see citing works
Fine structure of synaptic sites and circuits in mushroom bodies of insect brains
Schürmann, F. (2016) · Arthropod Structure & Development · doi:10.1016/j.asd.2016.08.005 · Cited by 35 · see citing works
A Context-Aware Delayed Agglomeration Framework for Electron Microscopy Segmentation
Parag, T., Chakraborty, A., Plaza, S. M., & Scheffer, L. K. (2015) · PLoS ONE · doi:10.1371/journal.pone.0125825 · Cited by 33 · see citing works
Self-citationMatsumoto, M. Y., Sasaki, K., Sato, M., Shozushima, M., & Takashima, K. (1988) · The Journal of Physiology · doi:10.1113/jphysiol.1988.sp017410 · Cited by 28 · see citing works
Small Sample Learning of Superpixel Classifiers for EM Segmentation
Parag, T., Plaza, S. M., & Scheffer, L. K. (2014) · Lecture notes in computer science · doi:10.1007/978-3-319-10404-1_49 · Cited by 17 · see citing works
Self-citationIdentifying Synapses Using Deep and Wide Multiscale Recursive NetworksPreprint
Huang, G. B., & Plaza, S. M. (2014) · arXiv (Cornell University) · doi:10.48550/arxiv.1409.1789 · Cited by 12 · see citing works
Self-citationLarge-Scale Electron Microscopy Image Segmentation in SparkPreprint
Plaza, S. M., & Berg, S. (2016) · arXiv (Cornell University) · doi:10.48550/arxiv.1604.00385 · Cited by 10 · see citing works
Self-citationWu, C., Shih, M.-F. M., Lai, J. S.-Y., Yang, H.-T., Turner, G. C., Chen, L., & Chiang, A. (2010) · F1000Research · doi:10.7490/f1000research.657.1 · Cited by 1 · see citing works
Self-citationGenes involved in sex pheromones discrimination and their context-dependent effect
Houot, B., Greenspan, R. J., & Ferveur, J. (2010) · HAL · Cited by 1 · see citing works
Flagged first, then by citations
1 of the 152 references couldn’t be matched to a known paper.
Research works printed but not linked: 4
- Eichler K LI, F Litwin-Kumar A Park Y Andrade I Schneider-Mizell C Saumweber T Huser A Eschbach C Gerber B Fetter RD Truman JW Priebe C Abbott LF Thum A Zlatic M Cardona A 2017 The complete wiring diagram of the larval Drosophila mushroom body Nature In press
- Qin H Cressy M Li W Coravos JS Izzi SA Dubnau J 2012b Gamma neurons mediate dopaminergic input during aversive olfactory memory formation in Drosophila Current Biology 22 608 614 10.1016/j.cub.2012.02.014 22425153 PMC3326180 · DOI
- Schürmann FW 1974 [On the functional anatomy of the corpora pedunculata in insects (author's transl)] Experimental Brain Research 19 406 432 4827867
- Yu D Keene AC Srivatsan A Waddell S Davis RL 2005b Drosophila DPM neurons form a delayed and branch-specific memory trace after olfactory classical conditioning Cell 123 945 957 10.1016/j.cell.2005.09.037 16325586 · DOI
Cited by
Sorted by citations
A connectome and analysis of the adult Drosophila central brain
Scheffer, L. K., Xu, C. S., Januszewski, M., Lu, Z., Takemura, S.-Y., Hayworth, K. J., Huang, G. B., Shinomiya, K., Maitlin-Shepard, J., Berg, S., et al. (2020) · eLife · doi:10.7554/elife.57443 · Cited by 1,128 · see citing works
“Previous reconstructions were either dense in much smaller EM volumes (such as Meinertzhagen and O’Neil, 1991; Helmstaedter et al., 2013; Takemura et al., 2017) or sparse in larger volumes (such as Eichler et al.”
BackgroundInfluentialSelf-citationA Complete Electron Microscopy Volume of the Brain of Adult Drosophila melanogaster
Zheng, Z., Lauritzen, J. S., Perlman, E., Robinson, C. G., Nichols, M., Milkie, D., Torrens, O., Price, J., Fisher, C. B., Sharifi, N., et al. (2018) · Cell · doi:10.1016/j.cell.2018.06.019 · Cited by 1,050 · see citing works
The complete connectome of a learning and memory centre in an insect brain
Eichler, K., Li, F., Litwin-Kumar, A., Park, Y., Andrade, I. V., Schneider-Mizell, C. M., Saumweber, T., Huser, A., Eschbach, C., Gerber, B., et al. (2017) · Nature · doi:10.1038/nature23455 · Cited by 494 · see citing works
The connectome of an insect brain
Winding, M., Pedigo, B. D., Barnes, C. L., Patsolic, H. G., Park, Y., Kazimiers, T., Fushiki, A., Andrade, I. V., Khandelwal, A., Valdes-Aleman, J., et al. (2023) · Science · doi:10.1126/science.add9330 · Cited by 435 · see citing works
Whole-brain annotation and multi-connectome cell typing of Drosophila
Schlegel, P., Yin, Y., Bates, A. S., Dorkenwald, S., Eichler, K., Brooks, P., Han, D. S., Gkantia, M., dos Santos, M., Munnelly, E. J., et al. (2024) · Nature · doi:10.1038/s41586-024-07686-5 · Cited by 413 · see citing works
Hulse, B. K., Haberkern, H., Franconville, R., Turner-Evans, D., Takemura, S.-Y., Wolff, T., Noorman, M., Dreher, M., Dan, C., Parekh, R., et al. (2021) · eLife · doi:10.7554/elife.66039 · Cited by 392 · see citing works
Self-citationThe connectome of the adult Drosophila mushroom body provides insights into function
Li, F., Lindsey, J. W., Marin, E. C., Otto, N., Dreher, M., Dempsey, G., Stark, I., Bates, A. S., Pleijzier, M. W., Schlegel, P., et al. (2020) · eLife · doi:10.7554/elife.62576 · Cited by 403 · see citing works
Self-citationCortical column and whole-brain imaging with molecular contrast and nanoscale resolution
Gao, R., Asano, S. M., Upadhyayula, S., Pisarev, I., Milkie, D. E., Liu, T., Singh, V. P., Graves, A. R., Huynh, G. H., Zhao, Y., et al. (2019) · Science · doi:10.1126/science.aau8302 · Cited by 375 · see citing works
Self-citationRecent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior
Nässel, D. R., & Zandawala, M. (2019) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2019.02.003 · Cited by 367 · see citing works
Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomics
Croset, V., Treiber, C. D., & Waddell, S. (2018) · eLife · doi:10.7554/elife.34550 · Cited by 299 · see citing works
Cognigni, P., Felsenberg, J., & Waddell, S. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.12.002 · Cited by 281 · see citing works
The natverse, a versatile toolbox for combining and analysing neuroanatomical data
Bates, A. S., Manton, J. D., Jagannathan, S. R., Costa, M., Schlegel, P., Rohlfing, T., & Jefferis, G. S. (2020) · eLife · doi:10.7554/elife.53350 · Cited by 215 · see citing works
Genetic Reagents for Making Split-GAL4 Lines in <i>Drosophila</i>
Dionne, H., Hibbard, K. L., Cavallaro, A., Kao, J.-C., & Rubin, G. M. (2018) · Genetics · doi:10.1534/genetics.118.300682 · Cited by 232 · see citing works
Self-citationThe Drosophila Mushroom Body: From Architecture to Algorithm in a Learning Circuit
Modi, M. N., Shuai, Y., & Turner, G. C. (2020) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-080317-0621333 · Cited by 216 · see citing works
Self-citationTsao, C.-H., Chen, C.-C., Lin, C.-H., Yang, H.-Y., & Lin, S. (2018) · eLife · doi:10.7554/elife.35264 · Cited by 214 · see citing works
Wolff, T., & Rubin, G. M. (2018) · Journal of Comparative Neurology · doi:10.1002/cne.24512 · Cited by 156 · see citing works
Self-citationAn open-access volume electron microscopy atlas of whole cells and tissues
Xu, C. S., Pang, S., Shtengel, G. E., Müller, A., Ritter, A. T., Hoffman, H. K., Takemura, S.-Y., Lu, Z., Pasolli, H. A., Iyer, N., et al. (2021) · Nature · doi:10.1038/s41586-021-03992-4 · Cited by 189 · see citing works
Self-citationDolan, M.-J., Frechter, S., Bates, A. S., Dan, C., Huoviala, P., Roberts, R. J., Schlegel, P., Dhawan, S., Tabano, R., Dionne, H., et al. (2019) · eLife · doi:10.7554/elife.43079 · Cited by 169 · see citing works
Self-citationWeight Agnostic Neural Networks
Gaier, A., & Ha, D. (2019) · Unpublished · doi:10.13140/rg.2.2.16025.88169 · Cited by 161 · see citing works
Recurrent architecture for adaptive regulation of learning in the insect brain
Eschbach, C., Fushiki, A., Winding, M., Schneider-Mizell, C. M., Shao, M., Arruda, R., Eichler, K., Valdés-Alemán, J., Ohyama, T., Thum, A. S., et al. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-0607-9 · Cited by 178 · see citing works
neuPrint: an open access tool for EM connectomics
Plaza, S. M., Clements, J., Dolafi, T., Umayam, L., Neubarth, N. N., Scheffer, L. K., & Berg, S. (2022) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2022.896292 · Cited by 145 · see citing works
Self-citationKondo, S., Takahashi, T., Yamagata, N., Imanishi, Y., Katow, H., Hiramatsu, S., Lynn, K., Abe, A., Kumaraswamy, A., & Tanimoto, H. (2020) · Cell Reports · doi:10.1016/j.celrep.2019.12.018 · Cited by 154 · see citing works
A Connectome of the Adult Drosophila Central BrainPreprint
Xu, C. S., Januszewski, M., Lu, Z., Takemura, S.-Y., Hayworth, K. J., Huang, G. B., Shinomiya, K., Maitin-Shepard, J., Ackerman, D., Berg, S., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.01.21.911859 · Cited by 150 · see citing works
Self-citationAso, Y., Ray, R. P., Long, X., Bushey, D., Cichewicz, K., Ngo, T.-T., Sharp, B., Christoforou, C., Hu, A., Lemire, A. L., et al. (2019) · eLife · doi:10.7554/elife.49257 · Cited by 141 · see citing works
Self-citationA Neural Circuit Arbitrates between Persistence and Withdrawal in Hungry Drosophila
Sayın, S., Backer, J. D., Siju, K. P., Wosniack, M. E., Lewis, L., Frisch, L. M., Gansen, B. O., Schlegel, P., Edmondson-Stait, A. J., Sharifi, N., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.07.028 · Cited by 144 · see citing works
Dopamine Neurons Mediate Learning and Forgetting through Bidirectional Modulation of a Memory Trace
Berry, J. A., Phan, A., & Davis, R. L. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.09.051 · Cited by 140 · see citing works
Fundamental principles of the olfactory code
Grabe, V., & Sachse, S. (2017) · Biosystems · doi:10.1016/j.biosystems.2017.10.010 · Cited by 140 · see citing works
Network statistics of the whole-brain connectome of Drosophila
Lin, A., Yang, R., Dorkenwald, S., Matsliah, A., Sterling, A. R., Schlegel, P., Yu, S.-C., McKellar, C. E., Costa, M., Eichler, K., et al. (2024) · Nature · doi:10.1038/s41586-024-07968-y · Cited by 147 · see citing works
“Many ascending and descending neurons appear to have high degrees when examined either within the brain or”
Nässel, D. R. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00083 · Cited by 119 · see citing works
Inverse resource allocation between vision and olfaction across the genus Drosophila
Keesey, I. W., Grabe, V., Gruber, L., Koerte, S., Obiero, G. F., Bolton, G., Khallaf, M. A., Kunert, G., Lavista-Llanos, S., Valenzano, D. R., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09087-z · Cited by 115 · see citing works
Heinrich, L., Funke, J., Pape, C., Nunez-Iglesias, J., & Saalfeld, S. (2018) · Lecture Notes in Computer Science · doi:10.1007/978-3-030-00934-2_36 · Cited by 117 · see citing works
Progress and remaining challenges in high-throughput volume electron microscopy
Kornfeld, J. M. R., & Denk, W. T. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.04.030 · Cited by 117 · see citing works
Dolan, M.-J., Belliart-Guérin, G., Bates, A. S., Frechter, S., Lampin-Saint-Amaux, A., Aso, Y., Roberts, R. J. V., Schlegel, P., Wong, A. M., Hammad, A., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.08.037 · Cited by 115 · see citing works
Self-citationSchlegel, P., Yin, Y., Bates, A. S., Dorkenwald, S., Eichler, K., Brooks, P., Han, D. S., Gkantia, M., dos Santos, M., Munnelly, E. J., et al. (2023) · doi:10.1101/2023.06.27.546055 · Cited by 102 · see citing works
Valence and State-Dependent Population Coding in Dopaminergic Neurons in the Fly Mushroom Body
Siju, K. P., Štih, V., Aimon, S., Gjorgjieva, J., Portugues, R., & Kadow, I. C. G. (2020) · Current Biology · doi:10.1016/j.cub.2020.04.037 · Cited by 110 · see citing works
Pavlowsky, A., Schor, J., Plaçais, P.-Y., & Préat, T. (2018) · Current Biology · doi:10.1016/j.cub.2018.04.040 · Cited by 94 · see citing works
Brain evolution in social insects: advocating for the comparative approach
Godfrey, R. K., & Gronenberg, W. (2019) · Journal of Comparative Physiology A · doi:10.1007/s00359-019-01315-7 · Cited by 87 · see citing works
Sun, J., Xu, A. Q., Giraud, J., Poppinga, H., Riemensperger, T. D., Fiala, A., & Birman, S. (2018) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2018.00006 · Cited by 89 · see citing works
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways
Zolin, A., Cohn, R., Pang, R., Siliciano, A. F., Fairhall, A. L., & Ruta, V. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00929-y · Cited by 81 · see citing works
Connectomics and function of a memory network: the mushroom body of larval Drosophila
Thum, A. S., & Gerber, B. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.10.007 · Cited by 89 · see citing works
Neuronal cell types in the fly: single-cell anatomy meets single-cell genomics
Bates, A. S., Janssens, J., Jefferis, G. S., & Aerts, S. (2019) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.12.012 · Cited by 70 · see citing works
Mushroom body evolution demonstrates homology and divergence across Pancrustacea
Strausfeld, N. J., Wolff, G. H., & Sayre, M. E. (2020) · eLife · doi:10.7554/elife.52411 · Cited by 83 · see citing works
Davis, R. L. (2023) · Genetics · doi:10.1093/genetics/iyad085 · Cited by 84 · see citing works
CAVE: Connectome Annotation Versioning Engine
Dorkenwald, S., Schneider-Mizell, C. M., Brittain, D., Halageri, A., Jordan, C. A., Kemnitz, N., Castro, M. A., Silversmith, W., Maitin-Shepard, J., Troidl, J., et al. (2025) · Nature Methods · doi:10.1038/s41592-024-02426-z · Cited by 80 · see citing works
Structured sampling of olfactory input by the fly mushroom body
Zheng, Z., Li, F., Fisher, C., Ali, I. J., Sharifi, N., Calle-Schuler, S., Hsu, J., Masoodpanah, N., Kmecova, L., Kazimiers, T., et al. (2022) · Current Biology · doi:10.1016/j.cub.2022.06.031 · Cited by 75 · see citing works
Dopamine promotes head direction plasticity during orienting movements
Fisher, Y. E., Marquis, M., D’Alessandro, I., & Wilson, R. I. (2022) · Nature · doi:10.1038/s41586-022-05485-4 · Cited by 67 · see citing works
Active Zone Scaffold Protein Ratios Tune Functional Diversity across Brain Synapses
Fulterer, A., Andlauer, T. F. M., Ender, A., Maglione, M., Eyring, K. W., Woitkuhn, J., Lehmann, M., Matkovic, T., Geiger, J. R. P., Walter, A. M., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.03.126 · Cited by 69 · see citing works
An open repository for single-cell reconstructions of the brain forest
Akram, M. A., Nanda, S., Maraver, P., Armañanzas, R., & Ascoli, G. A. (2018) · Scientific Data · doi:10.1038/sdata.2018.6 · Cited by 67 · see citing works
Persistent activity in a recurrent circuit underlies courtship memory in Drosophila
Zhao, X., Lenek, D., Dag, U., Dickson, B. J., & Keleman, K. (2018) · eLife · doi:10.7554/elife.31425 · Cited by 74 · see citing works
Large Volume Electron Microscopy and Neural Microcircuit Analysis
Kubota, Y., Sohn, J., & Kawaguchi, Y. (2018) · Frontiers in Neural Circuits · doi:10.3389/fncir.2018.00098 · Cited by 73 · see citing works
The Drosophila Split Gal4 System for Neural Circuit Mapping
Luan, H., Diao, F., Scott, R. L., & White, B. H. (2020) · Frontiers in Neural Circuits · doi:10.3389/fncir.2020.603397 · Cited by 73 · see citing works
RETRACTED ARTICLE: Multisensory learning binds neurons into a cross-modal memory engram
Okray, Z., Jacob, P. F., Stern, C., Desmond, K., Otto, N., Talbot, C. B., Vargas-Gutierrez, P., & Waddell, S. (2023) · Nature · doi:10.1038/s41586-023-06013-8 · Cited by 78 · see citing works
RetractedLocal 5-HT signaling bi-directionally regulates the coincidence time window for associative learning
Zeng, J., Li, X., Zhang, R., Lv, M., Wang, Y., Tan, K., Xia, X., Wan, J., Jing, M., Zhang, X., et al. (2023) · Neuron · doi:10.1016/j.neuron.2022.12.034 · Cited by 78 · see citing works
Valdés-Alemán, J., Fetter, R. D., Sales, E. C., Heckman, E. L., Venkatasubramanian, L., Doe, C. Q., Landgraf, M., Cardona, A., & Zlatic, M. (2020) · Neuron · doi:10.1016/j.neuron.2020.10.004 · Cited by 77 · see citing works
Rapid reconstruction of neural circuits using tissue expansion and light sheet microscopy
Lillvis, J. L., Otsuna, H., Ding, X., Pisarev, I., Kawase, T., Colonell, J. I., Rokicki, K., Goina, C., Gao, R., Hu, A., et al. (2022) · eLife · doi:10.7554/elife.81248 · Cited by 69 · see citing works
Dopamine modulation of sensory processing and adaptive behavior in flies
Siju, K. P., Backer, J. D., & Kadow, I. C. G. (2021) · Cell and Tissue Research · doi:10.1007/s00441-020-03371-x · Cited by 66 · see citing works
<i>neu</i> Print: Analysis Tools for EM Connectomics
Clements, J., Dolafi, T., Umayam, L., Neubarth, N. L., Berg, S., Scheffer, L. K., & Plaza, S. M. (2020) · doi:10.1101/2020.01.16.909465 · Cited by 65 · see citing works
Self-citationZhou, M., Chen, N., Tian, J., Zeng, J., Zhang, Y., Zhang, X., Guo, J., Sun, J., Li, Y., Guo, A., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1812342116 · Cited by 65 · see citing works
Circuits for integrating learned and innate valences in the insect brain
Eschbach, C., Fushiki, A., Winding, M., Afonso, B., Andrade, I. V., Cocanougher, B., Eichler, K., Gepner, R., Si, G., Valdés-Alemán, J., et al. (2021) · eLife · doi:10.7554/elife.62567 · Cited by 70 · see citing works
Localized inhibition in the Drosophila mushroom body
Amin, H., Apostolopoulou, A. A., Suárez-Grimalt, R., Vrontou, E., & Lin, A. C. (2020) · eLife · doi:10.7554/elife.56954 · Cited by 66 · see citing works
Sayın, S., Boehm, A. C., Kobler, J. M., Backer, J. D., & Kadow, I. C. G. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00011 · Cited by 60 · see citing works
The Role of Dopamine in Associative Learning in Drosophila: An Updated Unified Model
Adel, M., & Griffith, L. C. (2021) · Neuroscience Bulletin · doi:10.1007/s12264-021-00665-0 · Cited by 64 · see citing works
Visualization of a Distributed Synaptic Memory Code in the Drosophila Brain
Bilz, F., Geurten, B. R. H., Hancock, C. E., Widmann, A., & Fiala, A. (2019) · Neuron · doi:10.1016/j.neuron.2020.03.010 · Cited by 65 · see citing works
t-GRASP, a targeted GRASP for assessing neuronal connectivity
Shearin, H. K., Quinn, C. D., Mackin, R. D., Macdonald, I. S., & Stowers, R. S. (2018) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2018.05.014 · Cited by 60 · see citing works
Conservation and divergence of related neuronal lineages in the Drosophila central brain
Lee, Y.-J., Yang, C.-P., Miyares, R. L., Huang, Y.-F., He, Y., Ren, Q., Chen, H.-M., Kawase, T., Ito, M., Otsuna, H., et al. (2020) · eLife · doi:10.7554/elife.53518 · Cited by 60 · see citing works
Self-citationBielopolski, N., Amin, H., Apostolopoulou, A. A., Rozenfeld, E., Lerner, H., Huetteroth, W., Lin, A. C., & Parnas, M. (2019) · eLife · doi:10.7554/elife.48264 · Cited by 58 · see citing works
Li, P. H., Lindsey, L. F., Januszewski, M., Zheng, Z., Bates, A. S., Taisz, I., Tyka, M., Nichols, M., Li, F., Perlman, E., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/605634 · Cited by 60 · see citing works
Learning with reinforcement prediction errors in a model of the Drosophila mushroom body
Bennett, J., Philippides, A. O., & Nowotny, T. (2021) · Nature Communications · doi:10.1038/s41467-021-22592-4 · Cited by 61 · see citing works
Transsynaptic mapping of Drosophila mushroom body output neurons
Scaplen, K. M., Talay, M., Fisher, J. D., Cohn, R., Sorkaç, A., Aso, Y., Barnea, G., & Kaun, K. R. (2021) · eLife · doi:10.7554/elife.63379 · Cited by 56 · see citing works
Self-citationMcCurdy, L. Y., Sareen, P., Davoudian, P. A., & Nitabach, M. N. (2021) · Nature Communications · doi:10.1038/s41467-021-21388-w · Cited by 67 · see citing works
A resource for the Drosophila antennal lobe provided by the connectome of glomerulus VA1v
Horne, J. A., Langille, C., McLin, S., Wiederman, M., Lu, Z., Xu, C. S., Plaza, S. M., Scheffer, L. K., Hess, H. F., & Meinertzhagen, I. A. (2018) · eLife · doi:10.7554/elife.37550 · Cited by 46 · see citing works
Self-citationState-dependent plasticity of innate behavior in fruit flies
Kadow, I. C. G. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.08.014 · Cited by 57 · see citing works
Cellular and circuit mechanisms of olfactory associative learning in Drosophila
Boto, T., Stahl, A., & Tomchik, S. M. (2020) · Journal of Neurogenetics · doi:10.1080/01677063.2020.1715971 · Cited by 61 · see citing works
Shih, M.-F. M., Davis, F. P., Henry, G. L., & Dubnau, J. (2018) · G3 Genes Genomes Genetics · doi:10.1534/g3.118.200726 · Cited by 55 · see citing works
A set of hub neurons and non-local connectivity features support global brain dynamics in C. elegans
Uzel, K., Kato, S., & Zimmer, M. (2022) · Current Biology · doi:10.1016/j.cub.2022.06.039 · Cited by 54 · see citing works
Learning from connectomics on the fly.
Schlegel, P., Costa, M., & Jefferis, G. (2017) · Current Opinion in Insect Science · doi:10.1016/j.cois.2017.09.011 · Cited by 47 · see citing works
Of what use is connectomics? A personal perspective on the<i>Drosophila</i>connectome
Meinertzhagen, I. A. (2018) · Journal of Experimental Biology · doi:10.1242/jeb.164954 · Cited by 53 · see citing works
A neural data structure for novelty detection
Dasgupta, S., Sheehan, T. C., Stevens, C. F., & Navlakha, S. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1814448115 · Cited by 49 · see citing works
Hulse, B. K., Haberkern, H., Franconville, R., Turner-Evans, D. B., Takemura, S., Wolff, T., Noorman, M., Dreher, M., Dan, C., Parekh, R., et al. (2020) · doi:10.1101/2020.12.08.413955 · Cited by 392 · see citing works
“This recent history gives us reason to expect that connectomics (Eichler et al., 2017; Ohyama et al., 2015; Schlegel et al., 2020; Takemura et al., 2017a; Takemura et al., 2017b; White et al., 1986; Zheng et al., 2018) will continue to accelerate studies of circuit function (Bentley et al., 2016;…”
BackgroundInfluentialSelf-citationReward signaling in a recurrent circuit of dopaminergic neurons and peptidergic Kenyon cells
Lyutova, R., Selcho, M., Pfeuffer, M., Segebarth, D., Habenstein, J., Rohwedder, A., Frantzmann, F., Wegener, C., Thum, A. S., & Pauls, D. (2019) · Nature Communications · doi:10.1038/s41467-019-11092-1 · Cited by 51 · see citing works
Lateral Axonal Modulation Is Required for Stimulus-Specific Olfactory Conditioning in Drosophila
Manoim, J. E., Davidson, A. M., Weiss, S., Hige, T., & Parnas, M. (2022) · Current Biology · doi:10.1016/j.cub.2022.09.007 · Cited by 54 · see citing works
Self-citationA single-cell transcriptomic atlas of complete insect nervous systems across multiple life stages
Corrales, M., Cocanougher, B., Kohn, A. B., Wittenbach, J. D., Long, X., Lemire, A. L., Cardona, A., Singer, R. H., Moroz, L. L., & Zlatic, M. (2022) · Neural Development · doi:10.1186/s13064-022-00164-6 · Cited by 50 · see citing works
Linking physiological processes and feeding behaviors by octopamine
Selcho, M., & Pauls, D. (2019) · Current Opinion in Insect Science · doi:10.1016/j.cois.2019.09.002 · Cited by 49 · see citing works
Versatile Emulation of Spiking Neural Networks on an Accelerated Neuromorphic Substrate
Billaudelle, S., Stradmann, Y., Schreiber, K., Cramer, B., Baumbach, A., Dold, D., Göltz, J., Kungl, Á. F., Wunderlich, T. C., Hartel, A., et al. (2020) · IEEE International Symposium on Circuits and Systems proceedings · doi:10.1109/iscas45731.2020.9180741 · Cited by 48 · see citing works
Differential coding of absolute and relative aversive value in the Drosophila brain
Villar, M. E., Pavão-Delgado, M., Amigo, M., Jacob, P. F., Merabet, N., Pinot, A., Perry, S. A., Waddell, S., & Perisse, E. (2022) · Current Biology · doi:10.1016/j.cub.2022.08.058 · Cited by 55 · see citing works
Dopamine-mediated interactions between short- and long-term memory dynamics
Huang, C., Luo, J., Woo, S. J., Roitman, L. A., Li, J., Pieribone, V. A., Kannan, M., Vasan, G., & Schnitzer, M. J. (2024) · Nature · doi:10.1038/s41586-024-07819-w · Cited by 53 · see citing works
NeuTu: Software for Collaborative, Large-Scale, Segmentation-Based Connectome Reconstruction
Zhao, T., Olbris, D. J., Yu, Y., & Plaza, S. M. (2018) · Frontiers in Neural Circuits · doi:10.3389/fncir.2018.00101 · Cited by 47 · see citing works
Self-citationMusso, P., Junca, P., Jelen, M., Feldman-Kiss, D., Zhang, H., Chan, R. C. W., & Gordon, M. D. (2019) · eLife · doi:10.7554/elife.45636 · Cited by 48 · see citing works
Fully-Automatic Synapse Prediction and Validation on a Large Data Set
Huang, G. B., Scheffer, L. K., & Plaza, S. M. (2018) · Frontiers in Neural Circuits · doi:10.3389/fncir.2018.00087 · Cited by 46 · see citing works
Self-citationModelling Learning and Memory in Drosophila to Understand Intellectual Disabilities
Mariano, V., Achsel, T., Bagni, C., & Kanellopoulos, A. K. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.07.034 · Cited by 46 · see citing works
Circuits for integrating learned and innate valences in the insect brain.
Eschbach, C., Fushiki, A., Winding, M., Afonso, B., Andrade, I. V., Cocanougher, B., Eichler, K., Gepner, R., Si, G., Valdés-Alemán, J., et al. (2020) · Apollo (University of Cambridge) · doi:10.17863/cam.78882 · Cited by 45 · see citing works
The making of the Drosophila mushroom body
Lin, S. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1091248 · Cited by 40 · see citing works
Drosophila species learn dialects through communal living
Kacsoh, B. Z., Bozler, J., & Bosco, G. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007430 · Cited by 42 · see citing works
Exploiting Multiple Timescales in Hierarchical Echo State Networks
Manneschi, L., Ellis, M. O. A., Gigante, G., Lin, A. C., Giudice, P. D., & Vasilaki, E. (2021) · Frontiers in Applied Mathematics and Statistics · doi:10.3389/fams.2020.616658 · Cited by 42 · see citing works
Predictive olfactory learning in Drosophila
Zhao, C., Widmer, Y. F., Diegelmann, S., Petrovici, M. A., Sprecher, S. G., & Senn, W. (2021) · Scientific Reports · doi:10.1038/s41598-021-85841-y · Cited by 45 · see citing works
Octopamine mediates sugar relief from a chronic-stress-induced depression-like state in Drosophila
Hermanns, T., Graf-Boxhorn, S., Poeck, B., & Strauß, R. (2022) · Current Biology · doi:10.1016/j.cub.2022.07.016 · Cited by 37 · see citing works
Recent Advances in the Genetic Dissection of Neural Circuits in Drosophila
Guo, C., Pan, Y., & Gong, Z. (2019) · Neuroscience Bulletin · doi:10.1007/s12264-019-00390-9 · Cited by 40 · see citing works
An optogenetic analogue of second-order reinforcement in Drosophila
König, C., Khalili, A., Niewalda, T., Gao, S., & Gerber, B. (2019) · Biology Letters · doi:10.1098/rsbl.2019.0084 · Cited by 40 · see citing works
Toward an MRI-Based Mesoscale Connectome of the Squid Brain
Chung, W., Kurniawan, N. D., & Marshall, N. J. (2020) · iScience · doi:10.1016/j.isci.2019.100816 · Cited by 40 · see citing works
Schleyer, M. H., Weiglein, A., Thoener, J., Strauch, M., Hartenstein, V., Weigelt, M. K., Schuller, S., Saumweber, T., Eichler, K., Rohwedder, A., et al. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.0290-20.2020 · Cited by 40 · see citing works
- Authors
- Takemura, S.-Y., Aso, Y., Hige, T., Wong, A., Lu, Z., Xu, C. S., Rivlin, P. K., Hess, H., Zhao, T., Parag, T., Berg, S., Huang, G., Katz, W., Olbris, D. J., Plaza, S., Umayam, L., Aniceto, R., Chang, L.-A., Lauchie, S., Ogundeyi, O., Ordish, C., Shinomiya, A., Sigmund, C., Takemura, S., Tran, J., Turner, G. C., Rubin, G. M., & Scheffer, L. K.
- Affiliations
- Howard Hughes Medical Institute (US)
- Corresponding author
- Takemura, Shin-ya
- Scheffer, Louis K
- ORCID
- Takemura, Shin-ya
- Aso, Yoshinori
- Hige, Toshihide
- Wong, Allan
- Lu, Zhiyuan
- Xu, C Shan
- Rivlin, Patricia K
- Hess, Harald
- Zhao, Ting
- Berg, Stuart
- Huang, Gary
- Katz, William
- Olbris, Donald J
- Plaza, Stephen
- Umayam, Lowell
- Aniceto, Roxanne
- Lauchie, Shirley
- Ogundeyi, Omotara
- Ordish, Christopher
- Shinomiya, Aya
- Takemura, Satoko
- Tran, Julie
- Turner, Glenn C
- Rubin, Gerald M
- Scheffer, Louis K
- Venue
- eLife
- Publisher
- eLife Sciences Publications, Ltd
- Published
- 2017-07-18
- Volume
- 6
- ISSN
- 2050-084X (ISSN-L)
- PMC
- PMC5550281
- OpenAlex
- W2737808707
- Cited by
- 367
- References
- 152
- Citations by year
- 2026: 16 · 2025: 18 · 2024: 44 · 2023: 32 · 2022: 35 · 2021: 47 · 2020: 59 · 2019: 54 · 2018: 53 · 2017: 8 · 2014: 1
- FWCI
- 23.30
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- eLife (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Howard Hughes Medical Institute
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- mushroom body, Kenyon cells, dopaminergic neurons, synaptic connectivity, memory retrieval, associative learning, Drosophila, connectome, neuronal morphology, sensory modality specificity
- MeSH terms
- Animals, Drosophila, Learning, Memory, Mushroom Bodies, Connectome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
