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Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding

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Rare Genomic Variants Link Bipolar Disorder with Anxiety Disorders to CREB-Regulated Intracellular Signaling Pathways

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LRP6 exerts non-canonical effects on Wnt signaling during neural tube closure

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The conserved transmembrane RING finger protein PLR-1 downregulates Wnt signaling by reducing Frizzled, Ror and Ryk cell-surface levels in C. elegans

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Regulation of Dynamic Protein S-Acylation

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Rare LRP6 Variants Identified in Spina Bifida Patients

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Specificity of WNT-receptor interactions

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Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Cells

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The MRH Protein Erlectin Is a Member of the Endoplasmic Reticulum Synexpression Group and Functions in N-Glycan Recognition

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Tyrosine-based Signal Mediates LRP6 Receptor Endocytosis and Desensitization of Wnt/β-Catenin Pathway Signaling

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Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion

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Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivo

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Novel ubiquitin-dependent quality control in the endoplasmic reticulum

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CRELD2 Is a Novel LRP1 Chaperone That Regulates Noncanonical WNT Signaling in Skeletal Development

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Regulation of developmental intercellular signalling by intracellular trafficking

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Pyrosequencing of Haliotis diversicolor Transcriptomes: Insights into Early Developmental Molluscan Gene Expression

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Stepwise pluripotency transitions in mouse stem cells

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LRP5/6 in Wnt Signaling and Tumorigenesis

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Wise retained in the endoplasmic reticulum inhibits Wnt signaling by reducing cell surface LRP6

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LRPs in WNT Signalling

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A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease

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Cooperative Folding and Ligand-binding Properties of LRP6 β-Propeller Domains

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Inhibition of LRP5/6-mediated Wnt/β-catenin signaling by Mesd attenuates hyperoxia-induced pulmonary hypertension in neonatal rats

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Regulated N-glycosylation controls chaperone function and receptor trafficking

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Retinal Pigment Epithelium Under Oxidative Stress: Chaperoning Autophagy and Beyond

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The interplay of canonical and noncanonical Wnt signaling in metabolic syndrome

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The biology and inhibition of glucose‐regulated protein 94/gp96

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Physiological inhibitors of Wnt signaling

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LRP6 Ectodomain Prevents SDF-1/CXCR4-Induced Breast Cancer Metastasis to Lung

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ADAMTS9 and ADAMTS20 are differentially affected by loss of B3GLCT in mouse model of Peters plus syndrome

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A mutation in the signal sequence ofLRP5in a family with an osteoporosis-pseudoglioma syndrome (OPPG)-like phenotype indicates a novel disease mechanism for trinucleotide repeats

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Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25)

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Missense Mutations in LRP5 Are Not a Common Cause of Idiopathic Osteoporosis in Adult Men

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Immunization of mice with LRP4 induces myasthenia similar to MuSK-associated myasthenia gravis

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Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism

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Mutant MESD links cellular stress to type I collagen aggregation in osteogenesis imperfecta type XX

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Chemotherapy induces feedback up-regulation of CD44v6 in colorectal cancer initiating cells through β-catenin/MDR1 signaling to sustain chemoresistance

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The structure of receptor‐associated protein (RAP)

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Mustn1 is expressed during chondrogenesis and is necessary for chondrocyte proliferation and differentiation in vitro

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The Proteomic Analysis of Primary Cortical Astrocyte Cell Culture after Morphine Administration

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Mouse Tenm4 is required for mesoderm induction

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MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm

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High Bone Mass–Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo

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Modulation of LRP6‐mediated Wnt signaling by molecular chaperone Mesd

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Endoplasmic reticulum quality control in lipoprotein metabolism

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Early events in glutamate receptor trafficking

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Mesdc2 plays a key role in cell‐surface expression of Lrp4 and postsynaptic specialization in myotubes

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Two Structural and Functional Domains of MESD Required for Proper Folding and Trafficking of LRP5/6

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Emerging Landscape of Osteogenesis Imperfecta Pathogenesis and Therapeutic Approaches

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WNT-induced association of Frizzled and LRP6 is not sufficient for the initiation of WNT/β-catenin signaling

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A Bioinformatics Approach to Explore MicroRNAs as Tools to Bridge Pathways Between Plants and Animals. Is DNA Damage Response (DDR) a Potential Target Process?

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The promises of lysine polyphosphorylation as a regulatory modification in mammals are tempered by conceptual and technical challenges

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Identification of a putative transcriptome signature common to neuroblastoma and neural crest cells

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Linkage analysis localises a Kartagener syndrome gene to a 3.5 cM region on chromosome 15q24–25

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Talin rod domain–containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation

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Compound Heterozygous Frameshift Mutations in MESD Cause a Lethal Syndrome Suggestive of Osteogenesis Imperfecta Type XX

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Defective Human SRP Induces Protein Quality Control and Triggers Stress Response

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Gene targeting approaches in mice: assessing the roles of LRP5 and LRP6 in osteoblasts.

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A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling

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The C-Terminal Region Mesd Peptide Mimics Full-Length Mesd and Acts as an Inhibitor of Wnt/β-Catenin Signaling in Cancer Cells

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A cell‐based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild‐type and the high bone mass mutant LRP5(G171V)

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N-Glycosylation of LRP6 by B3GnT2 Promotes Wnt/β-Catenin Signalling

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Similarities and Differences Between the Wnt and Reelin Pathways in the Forming Brain

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The Structure of MESD45–184 Brings Light into the Mechanism of LDLR Family Folding

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Structural Characterization of the Boca/Mesd Maturation Factors for LDL-Receptor-Type β Propeller Domains

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Chapter 14 Real Time Investigation of Protein Folding, Structure, and Dynamics in Living Cells

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Extracellular LDLR repeats modulate Wnt signaling activity by promoting LRP6 receptor endocytosis mediated by the Itch E3 ubiquitin ligase

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