Cited by 832Heat shock proteins researchFungal and yeast genetics researchGenomics and Chromatin Dynamics

The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

Sorger, Peter K., Pelham, Hugh R.B.·1988·Cell

Open this paper in CoChat — free account

Abstract

Heat shock promoters contain one or more binding sites for a specific heat shock factor (HSF). We report the cloning and sequence of the gene encoding yeast HSF, and demonstrate that HSF is required for growth at normal temperatures (15 degrees C-30 degrees C). The activity of a promoter containing a synthetic HSF binding site varies over a 200-fold range between 15 degrees C and 39 degrees C (heat shock). This change in activity is accompanied by multiple changes in the phosphorylation state of HSF, but all forms of HSF are able to bind DNA. We propose that the expression of heat shock genes in yeast is modulated by phosphorylation of DNA-bound HSF, and that this leads to a more efficient interaction of the factor with other components of the transcriptional machinery.

Integrity signals

Registry

Crossref · 10.1016/s0092-8674(88)91219-6

Cites

29 of 29 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

THE HEAT-SHOCK RESPONSE
Lindquist, S. L. (1986) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.55.070186.005443 · Cited by 4,611
A short amino acid sequence able to specify nuclear location
Kalderon, D., Roberts, B., Richardson, W. D., & Smith, A. E. (1984) · Cell · doi:10.1016/0092-8674(84)90457-4 · Cited by 2,511
Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA
Chen, E. Y., & Seeburg, P. H. (1985) · DNA · doi:10.1089/dna.1985.4.165 · Cited by 2,388
A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance
Boeke, J. D., Lacroute, F., & Fink, G. R. (1984) · Molecular and General Genetics MGG · doi:10.1007/bf00330984 · Cited by 2,354
70K heat shock related proteins stimulate protein translocation into microsomes
Chirico, W. J., Waters, M. G., & Blobel, G. (1988) · Nature · doi:10.1038/332805a0 · Cited by 1,232
Yeast RNA Polymerase II Genes: Isolation with Antibody Probes
Young, R. A., & Davis, R. W. (1983) · Science · doi:10.1126/science.6356359 · Cited by 1,077
Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae
Johnston, M., & Davis, R. W. (1984) · Molecular and Cellular Biology · doi:10.1128/mcb.4.8.1440-1448.1984 · Cited by 980
Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast
Hope, I. A., & Struhl, K. (1986) · Cell · doi:10.1016/0092-8674(86)90070-x · Cited by 918
Deletion analysis of GAL4 defines two transcriptional activating segments
Ma, J., & Ptashne, M. (1987) · Cell · doi:10.1016/0092-8674(87)90081-x · Cited by 887
The Heat Shock Respons
Craig, E. A., & Schlesinger, M. J. (1985) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238509085135 · Cited by 809

Show all 27 references

Sorted by citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
Mitchell, P. J., & Tjian, R. (1989) · Science · doi:10.1126/science.2667136 · Cited by 3,046
The biochemistry and medical significance of the flavonoids
Havsteen, B. (2002) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(02)00298-x · Cited by 2,702
Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulatorsPreprint
Morimoto, R. I. (1998) · Genes & Development · doi:10.1101/gad.12.24.3788 · Cited by 1,898
Candida albicans pathogenicity mechanisms
Mayer, F. L., Wilson, D., & Hube, B. (2013) · Virulence · doi:10.4161/viru.22913 · Cited by 1,848
The Biology of Proteostasis in Aging and Disease
Labbadia, J., & Morimoto, R. I. (2015) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060614-033955 · Cited by 1,472
Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications
Ciocca, D. R., & Calderwood, S. K. (2005) · Cell Stress and Chaperones · doi:10.1379/csc-99r.1 · Cited by 1,420
Heat shock proteins.
Schlesinger, M. J. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38314-0 · Cited by 1,362
The regulation of transcription by phosphorylation
Hunter, T. R., & Karin, M. (1992) · Cell · doi:10.1016/0092-8674(92)90162-6 · Cited by 1,273
The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
Gottlieb, T. M., & Jackson, S. P. (1993) · Cell · doi:10.1016/0092-8674(93)90057-w · Cited by 1,233
The plant heat stress transcription factor (Hsf) family: Structure, function and evolution
Scharf, K., Berberich, T., Ebersberger, I., & Nover, L. (2011) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2011.10.002 · Cited by 1,159
Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity
Boyle, W. J., Smeal, T., Defize, L. H. K., Angel, P. E., Woodgett, J. R., Karin, M., & Hunter, T. R. (1991) · Cell · doi:10.1016/0092-8674(91)90241-p · Cited by 1,039
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
Pirkkala, L., NYKÄNEN, P., & Sistonen, L. (2001) · The FASEB Journal · doi:10.1096/fj00-0294rev · Cited by 996
Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element
Norman, C. M., Runswick, M. J., Pollock, R. M., & Treisman, R. (1988) · Cell · doi:10.1016/0092-8674(88)90244-9 · Cited by 933
Activation of Heat Shock Gene Transcription by Heat Shock Factor 1 Involves Oligomerization, Acquisition of DNA-Binding Activity, and Nuclear Localization and Can Occur in the Absence of Stress
Sarge, K. D., Murphy, S. P., & Morimoto, R. I. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.3.1392 · Cited by 883
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
Morimoto, R. I. (2008) · Genes & Development · doi:10.1101/gad.1657108 · Cited by 872
Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation
Storz, G., Tartaglia, L. A., & Ames, B. N. (1990) · Science · doi:10.1126/science.2183352 · Cited by 864
Stress (Heat Shock) Proteins
Benjamin, I. J., & McMillan, D. R. (1998) · Circulation Research · doi:10.1161/01.res.83.2.117 · Cited by 840
Regulation of H SF 1 Function in the Heat Stress Response: Implications in Aging and Disease
Anckar, J., & Sistonen, L. (2011) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060809-095203 · Cited by 811
&cestflwr; The Hsp90 family of proteins in Arabidopsis thaliana
Krishna, P., & Gloor, G. B. (2001) · Cell Stress and Chaperones · doi:10.1379/1466-1268(2001)006 · Cited by 360
A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells
Okamoto, K., Okazawa, H., Okuda, A., Sakai, M., Muramatsu, M., & Hamada, H. (1990) · Cell · doi:10.1016/0092-8674(90)90597-8 · Cited by 723
A Heat-Inducible Transcription Factor, HsfA2, Is Required for Extension of Acquired Thermotolerance in Arabidopsis
Charng, Y., Liu, H., Liu, N.-Y., Chi, W.-T., Wang, C., Chang, S.-H., & Wang, T.-T. (2006) · PLANT PHYSIOLOGY · doi:10.1104/pp.106.091322 · Cited by 693
Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation
Tanaka, M., & Herr, W. (1990) · Cell · doi:10.1016/0092-8674(90)90589-7 · Cited by 625
AGL1-AGL6, an Arabidopsis gene family with similarity to floral homeotic and transcription factor genes.Preprint
Mā, H., Yanofsky, M. F., & Meyerowitz, E. M. (1991) · Genes & Development · doi:10.1101/gad.5.3.484 · Cited by 623
Heat shock factor and the heat shock response
Sorger, P. K. (1991) · Cell · doi:10.1016/0092-8674(91)90452-5 · Cited by 603
Self-citation
A regulatory hierarchy for cell specialization in yeast
Herskowitz, I. (1989) · Nature · doi:10.1038/342749a0 · Cited by 590
Biology of the Heat Shock Response and Protein Chaperones: Budding Yeast (Saccharomyces cerevisiae) as a Model System
Verghese, J., Abrams, J., Wang, Y., & Morano, K. A. (2012) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.05018-11 · Cited by 575
HSF1 is required for extra‐embryonic development, postnatal growth and protection during inflammatory responses in mice
Xiao, X., Zuo, X., Davis, A. A., McMillan, D. R., Curry, B. B., Richardson, J. A., & Benjamin, I. J. (1999) · The EMBO Journal · doi:10.1093/emboj/18.21.5943 · Cited by 542
Regulation of Heat Shock Factor Trimer Formation: Role of a Conserved Leucine Zipper
Rabindran, S. K., Haroun, R. I., Clos, J., Wiśniewski, J., & Wu, C. (1993) · Science · doi:10.1126/science.8421783 · Cited by 489
The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response.Preprint
Kamada, Y., Jung, U. S., Piotrowski, J., & Levin, D. E. (1995) · Genes & Development · doi:10.1101/gad.9.13.1559 · Cited by 488
Could Heat Shock Transcription Factors Function as Hydrogen Peroxide Sensors in Plants?
Miller, G., & Mittler, R. (2006) · Annals of Botany · doi:10.1093/aob/mcl107 · Cited by 484
Msn2p, a zinc finger DNA-binding protein, is the transcriptional activator of the multistress response in Saccharomyces cerevisiae.
Schmitt, A. P., & McEntee, K. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.12.5777 · Cited by 472
DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9
Hanes, S. D., & Brent, R. (1989) · Cell · doi:10.1016/0092-8674(89)90063-9 · Cited by 464
Stress tolerance: The key to effective strains of industrial baker's yeast
Attfield, P. V. (1997) · Nature Biotechnology · doi:10.1038/nbt1297-1351 · Cited by 461
Activation of Human Heat Shock Genes Is Accompanied by Oligomerization, Modification, and Rapid Translocation of Heat Shock Transcription Factor HSF1
Baler, R., Dahl, G., & Voellmy, R. W. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.4.2486 · Cited by 460
Molecular cloning and expression of a human heat shock factor, HSF1.
Rabindran, S. K., Giorgi, G., Clos, J., & Wu, C. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.6906 · Cited by 456
The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain
Frain, M., Swart, G. W. M., Monaci, P., Nicosia, A., Stämpfli, S., Frank, R. W., & Cortese, R. (1989) · Cell · doi:10.1016/0092-8674(89)90877-5 · Cited by 454
Genome-Wide Analysis of the Biology of Stress Responses through Heat Shock Transcription Factor
Hahn, J., Hu, Z., Thiele, D. J., & Iyer, V. R. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.12.5249-5256.2004 · Cited by 438
Role of the AMP-activated protein kinase in the cellular stress response
Corton, J. M., Gillespie, J. G., & Hardie, D. G. (1994) · Current Biology · doi:10.1016/s0960-9822(00)00070-1 · Cited by 423
Transcriptional regulation of heat shock genes. A paradigm for inducible genomic responses.
Morimoto, R. I., Sarge, K. D., & Abravaya, K. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)41621-3 · Cited by 416
Stable binding of Drosophila heat shock factor to head-to-head and tail-to-tail repeats of a conserved 5 bp recognition unit
Perišić, O., Xiao, H., & Lis, J. T. (1989) · Cell · doi:10.1016/0092-8674(89)90603-x · Cited by 411
The Heat Shock Response: Systems Biology of Proteotoxic Stress in Aging and DiseasePreprint
Morimoto, R. (2011) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2012.76.010637 · Cited by 419
Stress signaling in yeast
Ruis, H., & Schüller, C. (1995) · BioEssays · doi:10.1002/bies.950171109 · Cited by 406
Effect of Sodium Salicylate on the Human Heat Shock Response
Jurivich, D. A., Sistonen, L., Kroes, R. A., & Morimoto, R. I. (1992) · Science · doi:10.1126/science.1546322 · Cited by 395
Sequential Phosphorylation by Mitogen-activated Protein Kinase and Glycogen Synthase Kinase 3 Represses Transcriptional Activation by Heat Shock Factor-1
Chu, B., Soncin, F., Price, B. D., Stevenson, M. A., & Calderwood, S. K. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.48.30847 · Cited by 382
Trimerization of a yeast transcriptional activator via a coiled-coil motif
Sorger, P. K., & Nelson, H. C. M. (1989) · Cell · doi:10.1016/0092-8674(89)90604-1 · Cited by 376
Self-citation
Stress-induced oligomerization and chromosomal relocalization of heat-shock factor
Westwood, J. T., Clos, J., & Wu, C. (1991) · Nature · doi:10.1038/353822a0 · Cited by 370
Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability.Preprint
Sarge, K. D., Zimarino, V., Holm, K., Wu, C., & Morimoto, R. I. (1991) · Genes & Development · doi:10.1101/gad.5.10.1902 · Cited by 367
Molecular cloning and expression of a hexameric Drosophila heat shock factor subject to negative regulation
Clos, J., Westwood, J. T., Becker, P. B., Wilson, S. E., Lambert, K. N., & Wu, C. (1990) · Cell · doi:10.1016/0092-8674(90)90511-c · Cited by 359
HSF4, a New Member of the Human Heat Shock Factor Family Which Lacks Properties of a Transcriptional Activator
Nakai, A., Tanabe, M., Kawazoe, Y., Inazawa, J., Morimoto, R. I., & Nagata, K. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.1.469 · Cited by 351
Stress-induced transcriptional activation
Mager, W. H., & Kruijff, A. J. D. (1995) · Microbiological Reviews · doi:10.1128/mr.59.3.506-531.1995 · Cited by 351
The Heat Stress Transcription Factor HsfA2 Serves as a Regulatory Amplifier of a Subset of Genes in the Heat Stress Response in Arabidopsis
Schramm, F., Ganguli, A., Kiehlmann, E., Englich, G., Walch, D., & von Koskull‐Döring, P. (2006) · Plant Molecular Biology · doi:10.1007/s11103-005-5750-x · Cited by 348
Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humans.
Schuetz, T. J., Gallo, G. J., Sheldon, L. A., Tempst, P., & Kingston, R. E. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.6911 · Cited by 339
Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1
Holmberg, C. I., Hietakangas, V., Mikhailov, A., Rantanen, J. O., Kallio, M. J., Meinander, A., Hellman, J., Morrice, N., MacKintosh, C., Morimoto, R. I., et al. (2001) · The EMBO Journal · doi:10.1093/emboj/20.14.3800 · Cited by 333
Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster.
Franke, A., DeCamillis, M. A., Zink, D., Cheng, N., Brock, H. W., & Paro, R. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05364.x · Cited by 330
A Novel Transcriptional Cascade Regulating Expression of Heat Stress Proteins during Seed Development of Arabidopsis
Kotak, S., Vierling, E., Bäumlein, H., & von Koskull‐Döring, P. (2007) · The Plant Cell · doi:10.1105/tpc.106.048165 · Cited by 324
Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress
Guettouche, T., Boellmann, F., Lane, W. S., & Voellmy, R. W. (2005) · BMC Biochemistry · doi:10.1186/1471-2091-6-4 · Cited by 328
Repression of the Heat Shock Factor 1 Transcriptional Activation Domain Is Modulated by Constitutive Phosphorylation
Kline, M. P., & Morimoto, R. I. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.4.2107 · Cited by 312
Mechanisms of Hsp90 regulation
Prodromou, C. (2016) · Biochemical Journal · doi:10.1042/bcj20160005 · Cited by 324
Tolerance and stress response to ethanol in the yeast Saccharomyces cerevisiae
Ding, J., Huang, X., Zhang, L., Zhao, N., Yang, D., & Zhang, K. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-009-2223-1 · Cited by 309
Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA‐binding domain of the yeast HSF.
Scharf, K., Rose, S., Zott, W., Schöffl, F., Nover, L., & Schöff, F. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07900.x · Cited by 306
Multiple functions of Drosophila heat shock transcription factor in vivo
Jedlicka, P., Mortin, M. A., & Wu, C. (1997) · The EMBO Journal · doi:10.1093/emboj/16.9.2452 · Cited by 306
HSF1 at a glance
Vihervaara, A., & Sistonen, L. (2014) · Journal of Cell Science · doi:10.1242/jcs.132605 · Cited by 321
Cellular stress response pathways and ageing: intricate molecular relationships
Kourtis, N., & Tavernarakis, N. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.162 · Cited by 312
Stress adaptation in a pathogenic fungus
Brown, A. J. P., Budge, S., Kaloriti, D., Tillmann, A., Jacobsen, M. D., Yin, Z., Ene, I. V., Bohovych, I., Sandai, D., Kastora, S., et al. (2014) · Journal of Experimental Biology · doi:10.1242/jeb.088930 · Cited by 299
Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis
Guo, J., Wu, J., Ji, Q., Wang, C., Luo, L., Yuan, Y., Wang, Y., & Wang, J. (2008) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/s1673-8527(08)60016-8 · Cited by 289
Activation of Heat Shock Factor 1 DNA Binding Precedes Stress-induced Serine Phosphorylation
Cotto, J. J., Kline, M. P., & Morimoto, R. I. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.7.3355 · Cited by 287
Yeast Stress Response and Fermentation Efficiency: How to Survive the Making of Wine – A Review
Bauer, F. F., & Pretorius, I. S. (2000) · South African Journal of Enology and Viticulture · doi:10.21548/21-1-3557 · Cited by 284
In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation.
Mosser, D. D., Kotzbauer, P. T., Sarge, K. D., & Morimoto, R. I. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.10.3748 · Cited by 280
Eukaryotic transcription factors
Latchman, D. S. (1990) · Biochemical Journal · doi:10.1042/bj2700281 · Cited by 271
Crystal Structure of the DNA Binding Domain of the Heat Shock Transcription Factor
Harrison, C. J., Bohm, A., & Nelson, H. C. M. (1994) · Science · doi:10.1126/science.8284672 · Cited by 275
Characterization of a Novel Chicken Heat Shock Transcription Factor, Heat Shock Factor 3, Suggests a New Regulatory Pathway
Nakai, A., & Morimoto, R. I. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.4.1983 · Cited by 266
Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update
Ciocca, D. R., Arrigo, A. P., & Calderwood, S. K. (2012) · Archives of Toxicology · doi:10.1007/s00204-012-0918-z · Cited by 278
Heat shock proteins, thermotolerance, and their relevance to clinical hyperthermia
Li, G. C., Mivechi, N. F., & Weitzel, G. (1995) · International Journal of Hyperthermia · doi:10.3109/02656739509022483 · Cited by 262
The Stress of Protein Misfolding: From Single Cells to Multicellular OrganismsPreprint
Gidalevitz, T., Prahlad, V., & Morimoto, R. I. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a009704 · Cited by 258
Diversity of plant heat shock factors: regulation, interactions, and functions
Andrási, N., Pettkó‐Szandtner, A., & Szabados, L. (2020) · Journal of Experimental Botany · doi:10.1093/jxb/eraa576 · Cited by 253
Chaperone Regulation of the Heat Shock Protein Response
Voellmy, R. W., & Boellmann, F. (2007) · Springer eBooks · doi:10.1007/978-0-387-39975-1_9 · Cited by 267
Cytosolic HSP90 Regulates the Heat Shock Response That Is Responsible for Heat Acclimation in Arabidopsis thaliana
Yamada, K., Fukao, Y., Hayashi, M., Fukazawa, M., Suzuki, I., & Nishimura, M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m707168200 · Cited by 251
Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation
Zheng, X., Krakowiak, J., Patel, N., Ali Beyzavi, B., Ezike, J., Khalil, A. S., & Pincus, D. (2016) · eLife · doi:10.7554/elife.18638 · Cited by 249
Glass encodes a site-specific DNA-binding protein that is regulated in response to positional signals in the developing Drosophila eye.Preprint
Moses, K., & Rubin, G. M. (1991) · Genes & Development · doi:10.1101/gad.5.4.583 · Cited by 243
The heat shock factor family and adaptation to proteotoxic stress
Fujimoto, M., & Nakai, A. (2010) · FEBS Journal · doi:10.1111/j.1742-4658.2010.07827.x · Cited by 251
Yeast heat shock factor contains separable transient and sustained response transcriptional activators
Sorger, P. K. (1990) · Cell · doi:10.1016/0092-8674(90)90123-v · Cited by 241
Self-citation
Heat Shock Factor 2 (HSF2) Contributes to Inducible Expression of hsp Genes through Interplay with HSF1
Östling, P., Björk, J., Roos‐Mattjus, P., Mezger, V., & Sistonen, L. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m607556200 · Cited by 238
Cooperative binding of drosophila heat shock factor to arrays of a conserved 5 bp unit
Xiao, H., Perišić, O., & Lis, J. T. (1991) · Cell · doi:10.1016/0092-8674(91)90242-q · Cited by 238
mTOR Is Essential for the Proteotoxic Stress Response, HSF1 Activation and Heat Shock Protein Synthesis
Chou, S., Prince, T. L., Gong, J., & Calderwood, S. K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039679 · Cited by 228
Negative regulation of the heat shock transcriptional response by HSBP1Preprint
Satyal, S. H., Chen, D., Fox, S. G., Kramer, J. M., & Morimoto, R. I. (1998) · Genes & Development · doi:10.1101/gad.12.13.1962 · Cited by 225
Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes
Workman, J. L., Taylor, I. C. A., & Kingston, R. E. (1991) · Cell · doi:10.1016/0092-8674(91)90237-s · Cited by 224
Activation of Heat Shock and Antioxidant Responses by the Natural Product Celastrol: Transcriptional Signatures of a Thiol-targeted Molecule
Trott, A. E., West, J. D., Klaić, L., Westerheide, S. D., Silverman, R. B., Morimoto, R. I., & Morano, K. A. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-10-1004 · Cited by 223
Heat-shock protein 104 expression is sufficient for thermotolerance in yeast.
Lindquist, S., & Kim, G. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.11.5301 · Cited by 223
Heat shock factors in rice (Oryza sativa L.): genome-wide expression analysis during reproductive development and abiotic stress
Chauhan, H., Khurana, N., Agarwal, P., & Khurana, P. (2011) · Molecular Genetics and Genomics · doi:10.1007/s00438-011-0638-8 · Cited by 218
Inhibition of the Activation of Heat Shock Factor In Vivo and In Vitro by Flavonoids
Hosokawa, N., Hirayoshi, K., Kudo, H., Takechi, H., Aoike, A., Kawai, K., & Nagata, K. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.8.3490 · Cited by 218
Casein kinase II inhibits the DNA-binding activity of Max homodimers but not Myc/Max heterodimers.Preprint
Berberich, S. J., & Cole, M. D. (1992) · Genes & Development · doi:10.1101/gad.6.2.166 · Cited by 218
Activation of Drosophila Heat Shock Factor: Conformational Change Associated with a Monomer-to-Trimer Transition
Westwood, J. T., & Wu, C. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.6.3481 · Cited by 213
The DNA-Binding Activity of the Human Heat Shock Transcription Factor Is Regulated In Vivo by hsp70
Mosser, D. D., Duchaine, J., & Bernard Massie, B. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.9.5427-5438.1993 · Cited by 211
Hepatitis B virus X‐gene product: A promiscuous transcriptional activator
Rossner, M. T. (1992) · Journal of Medical Virology · doi:10.1002/jmv.1890360207 · Cited by 211
Heat stress proteins and transcription factors
Nover, L., & Scharf, K. (1997) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000583 · Cited by 210
Stress response of yeast
Mager, W. H., & Ferreira, P. M. (1993) · Biochemical Journal · doi:10.1042/bj2900001 · Cited by 204
Evolution of gene networks by gene duplications: a mathematical model and its implications on genome organization.
Wagner, A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.10.4387 · Cited by 204
Direct Sensing of Heat and Oxidation by Drosophila Heat Shock Transcription Factor
Zhong, M., Orosz, A., & Wu, C. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80118-5 · Cited by 202
Inducibility of the response of yeast cells to peroxide stress
Collinson, L. P., & Dawes, I. W. (1992) · Journal of General Microbiology · doi:10.1099/00221287-138-2-329 · Cited by 202
Roles of heat shock factor 1 beyond the heat shock response
Barna, J., Csermely, P., & Vellai, T. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2836-6 · Cited by 214

Authors: Sorger, P. K., & Pelham, H. R. B.
Affiliations: MRC Laboratory of Molecular Biology (GB)
ORCID: Sorger, Peter K.
Pelham, Hugh R.B.
Venue: Cell
Publisher: Elsevier BV
Published: 1988-09
Volume: 54
Issue: 6
Pages: 855-864
ISSN: 0092-8674 (ISSN-L)
DOI: 10.1016/s0092-8674(88)91219-6
OpenAlex: W2005131012
Cited by: 832
References: 27
Citations by year: 2026: 8 · 2025: 6 · 2024: 12 · 2023: 6 · 2022: 21 · 2021: 10 · 2020: 16 · 2019: 11 · 2018: 15 · 2017: 10 · 2016: 22 · 2015: 9 · 2014: 15 · 2013: 25 · 2012: 17
FWCI: 24.28
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Cell (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Heat shock proteins research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
Keywords: heat shock transcription factor, Saccharomyces cerevisiae, heat shock promoter, protein phosphorylation, DNA binding, heat shock gene expression, transcriptional regulation, gene cloning
MeSH terms: Amino Acid Sequence, Base Sequence, Cell Survival, Cloning, Molecular, DNA-Binding Proteins, Gene Expression Regulation, Hot Temperature, Heat-Shock Proteins, Molecular Sequence Data, Molecular Weight, Phosphoproteins, Phosphorylation, Saccharomyces cerevisiae, Transcription Factors, Transcription, Genetic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks