Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

THE HEAT-SHOCK RESPONSE

Lindquist, S. L. (1986) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.55.070186.005443 · Cited by 4,611

A short amino acid sequence able to specify nuclear location

Kalderon, D., Roberts, B., Richardson, W. D., & Smith, A. E. (1984) · Cell · doi:10.1016/0092-8674(84)90457-4 · Cited by 2,511

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

Chen, E. Y., & Seeburg, P. H. (1985) · DNA · doi:10.1089/dna.1985.4.165 · Cited by 2,388

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

Boeke, J. D., Lacroute, F., & Fink, G. R. (1984) · Molecular and General Genetics MGG · doi:10.1007/bf00330984 · Cited by 2,354

70K heat shock related proteins stimulate protein translocation into microsomes

Chirico, W. J., Waters, M. G., & Blobel, G. (1988) · Nature · doi:10.1038/332805a0 · Cited by 1,232

Yeast RNA Polymerase II Genes: Isolation with Antibody Probes

Young, R. A., & Davis, R. W. (1983) · Science · doi:10.1126/science.6356359 · Cited by 1,077

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

Johnston, M., & Davis, R. W. (1984) · Molecular and Cellular Biology · doi:10.1128/mcb.4.8.1440-1448.1984 · Cited by 980

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

Hope, I. A., & Struhl, K. (1986) · Cell · doi:10.1016/0092-8674(86)90070-x · Cited by 918

Deletion analysis of GAL4 defines two transcriptional activating segments

Ma, J., & Ptashne, M. (1987) · Cell · doi:10.1016/0092-8674(87)90081-x · Cited by 887

The Heat Shock Respons

Craig, E. A., & Schlesinger, M. J. (1985) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238509085135 · Cited by 809

Heat shock protein inhibitors and vaccines as new agents in cancer treatment

Karapanagiotou, E. M., Syrigos, K., & Saif, M. W. (2009) · Expert Opinion on Investigational Drugs · doi:10.1517/13543780802715792 · Cited by 27

Conventional and novel PKC isoenzymes modify the heat-induced stress response but are not activated by heat shock

Holmberg, C. I., Roos‐Mattjus, P., Lord, J. M., Eriksson, J., & Sistonen, L. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.22.3357 · Cited by 27

Modular Recognition of 5-Base-Pair DNA Sequence Motifs by Human Heat Shock Transcription Factor

Cunniff, N. F. A., Wagner, J., & Morgan, W. D. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.7.3504 · Cited by 27

Phosphorylation influences the binding of the yeast RAP1 protein to the upstream activating sequence of thePGKgene

Tsang, J. S. H., Henry, Y. A. L., Chambers, A., Kingsman, A. J., & Kingsman, S. M. (1990) · Nucleic Acids Research · doi:10.1093/nar/18.24.7331 · Cited by 27

Okadaic acid induction of the urokinase‐type plasminogen activator gene occurs independently of cAMP‐dependent protein kinase and protein kinase C and is sensitive to protein synthesis inhibition.

Nagamine, Y., & Ziegler, A. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07927.x · Cited by 27

A Telomeric Cluster of Antimony Resistance Genes on Chromosome 34 of Leishmania infantum

Nevado, P. T., Bifeld, E., Höhn, K., & Clos, J. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00544-16 · Cited by 26

Yeast Protein Kinase A Isoforms: A Means of Encoding Specificity in the Response to Diverse Stress Conditions?

Creamer, D. R., Hubbard, S. J., Ashe, M., & Grant, C. M. (2022) · Biomolecules · doi:10.3390/biom12070958 · Cited by 26

Genome-Wide Identification of HSF Gene Family in Kiwifruit and the Function of AeHSFA2b in Salt Tolerance

Ling, C., Liu, Y., Yang, Z., Xu, J., Ouyang, Z., Yang, J., & Wang, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242115638 · Cited by 26

The SEB-1 Transcription Factor Binds to the STRE Motif in Neurospora crassa and Regulates a Variety of Cellular Processes Including the Stress Response and Reserve Carbohydrate Metabolism

Freitas, F. Z., Virgílio, S., Cupertino, F. B., Kowbel, D., Fioramonte, M., Gozzo, F. C., Glass, N. L., & Bertolini, M. C. (2016) · G3 Genes Genomes Genetics · doi:10.1534/g3.116.028506 · Cited by 26

Stochastic and Age‐Dependent Proteostasis Decline Underlies Heterogeneity in Heat‐Shock Response Dynamics

Vertti‐Quintero, N., Berger, S., Solvas, X. C. I., Statzer, C., Annis, J., Ruppen, P., Stavrakis, S., Ewald, C. Y., Gunawan, R., & deMello, A. J. (2021) · Small · doi:10.1002/smll.202102145 · Cited by 26

c-Ha -ras Down Regulates the α-Fetoprotein Gene but Not the Albumin Gene in Human Hepatoma Cells

Nakao, K., Lawless, D., Ohe, Y., Miyao, Y., Nakabayashi, H., Kamiya, H., Miura, K., Ohtsuka, E., & Tamaoki, T. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.4.1461 · Cited by 26

Stage‐specific phosphorylation of the fushi tarazu protein during Drosophila development.

Krause, H. M., & Gehring, W. J. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb03492.x · Cited by 26

Induction by HMBA and DMSO of genes introduced into mouse erythroleukemia and other cell lines by transient transfection.Preprint

Campbell, P. L., Kulozik, A. E., Jp, W., & Jones, R. W. (1990) · Genes & Development · doi:10.1101/gad.4.7.1252 · Cited by 26

In Silico Characterization and Expression Profiles of Heat Shock Transcription Factors (HSFs) in Maize (Zea mays L.)

Haider, S., Rehman, S., Ahmad, Y., Raza, A., Tabassum, J., Javed, T., Osman, H. S., & Mahmood, T. (2021) · Agronomy · doi:10.3390/agronomy11112335 · Cited by 26

Global Analysis of Phosphoproteome Regulation by the Ser/Thr Phosphatase Ppt1 in Saccharomyces cerevisiae

Schreiber, T. B., Mäusbacher, N., Soroka, J., Wandinger, S. K., Büchner, J., & Daub, H. (2012) · Journal of Proteome Research · doi:10.1021/pr201134p · Cited by 25

Identification and functional characterization of heat shock transcription factor1 in Litopenaeus vannamei

Yan, H., Zhang, S., Li, X., Yuan, F.-H., Qiu, W., Chen, Y.-G., Weng, S., He, J., & Chen, Y.-H. (2014) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2014.01.020 · Cited by 25

Dual functions of the ZmCCT-associated quantitative trait locus in flowering and stress responses under long-day conditions

Ku, L., Tian, L., Su, H., Wang, C., Wang, X., Wu, L., Shi, Y., Li, G., Wang, Z., Wang, H., et al. (2016) · BMC Plant Biology · doi:10.1186/s12870-016-0930-1 · Cited by 25

Loss of a phosphorylated form of transcription factor CREB/ATF in poliovirus-infected cells

Kliewer, S. A., Muchardt, C., Gaynor, R. B., & Dasgupta, A. (1990) · Journal of Virology · doi:10.1128/jvi.64.9.4507-4515.1990 · Cited by 25

Redox signaling of cardiac HSF1 DNA binding

Paroo, Z., Meredith, M. J., Locke, M., Haist, J. V., Karmazyn, M., & Noble, E. G. (2002) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00051.2002 · Cited by 25

HSF1 and HSF3 cooperatively regulate the heat shock response in lizards

Takii, R., Fujimoto, M., Matsuura, Y., Wu, F., Oshibe, N., Takaki, E., Katiyar, A., Akashi, H. D., Makino, T. T., Kawata, M., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180776 · Cited by 25

High constitutive transcription of HSP86 gene in murine embryonal carcinoma cells

Legagneux, V., Mezger, V., Quélard, C., Barnier, J., Bensaude, O., & Morange, M. (1989) · Differentiation · doi:10.1111/j.1432-0436.1989.tb00730.x · Cited by 25

Role of trehalose and heat in the structure of the C‐terminal activation domain of the heat shock transcription factor

Bulman, A. L., & Nelson, H. C. M. (2005) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.20371 · Cited by 25

Genetic interactions between SIN3 mutations and the Saccharomyces cerevisiae transcriptional activators encoded by MCM1, STE12, and SWI1

Wang, H., Reynolds-Hager, L., & Stillman, D. J. (1994) · Molecular and General Genetics MGG · doi:10.1007/bf00297274 · Cited by 25

Glycogen Synthase Phosphatase Interacts with Heat Shock Factor To Activate CUP1 Gene Transcription in Saccharomyces cerevisiae

Lin, J. T., & Lis, J. T. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.5.3237 · Cited by 25

An emerging role for protein kinases: The responses to nutritional and environmental stress

Hardie, D. G. (1994) · Cellular Signalling · doi:10.1016/0898-6568(94)90015-9 · Cited by 25

Genome-Wide Identification and Expression Analysis of the HSF Gene Family in Poplar

Zhao, K. X., Dang, H., Zhou, L., Hu, J. M., Jin, X., Han, Y., & Wang, S. (2023) · Forests · doi:10.3390/f14030510 · Cited by 24

Gaining insight into the response logic of Saccharomyces cerevisiae to heat shock by combining expression profiles with metabolic pathways

Ye, Y., Zhu, Y., Pan, L., Li, L., Wang, X., & Lin, Y. C. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.05.071 · Cited by 24

Xenopus Heat Shock Factor 1 Is a Nuclear Protein before Heat Stress

Mercier, P. A., Foksa, J., Ovsenek, N., & Westwood, J. T. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.22.14147 · Cited by 24

Transient increase in vimentin phosphorylation and vimentin‐HSC70 association in 9L rat brain tumor cells experiencing heat‐shock

Cheng, T.-J. R., & Lai, Y. (1994) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240540111 · Cited by 24

The Heat Shock Proteins and the Stress Response

Plesofsky-Vig, N. (1996) · Springer eBooks · doi:10.1007/978-3-662-10367-8_7 · Cited by 24

Effect of pH on quercetin-induced suppression of heat shock gene expression and thermotolerance development in HT-29 cells

Lee, Y. J., Curetty, L., Hou, Z., Kim, S. H., Kim, J. H., & Corry, P. M. (1992) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(92)90863-g · Cited by 24

Yeast transcription factors

Struhl, K. (1993) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(93)90018-l · Cited by 24

Pathology-Dependent Effects Linked to Small Heat Shock Proteins Expression: An Update

Arrigo, A. (2012) · Scientifica · doi:10.6064/2012/185641 · Cited by 26

Dynamics of heat shock proteins and heat shock factor expression during heat stress in daughter workers in pre-heat-treated (rapid heat hardening) Apis mellifera mother queens

Al‐Ghzawi, A. A., Al‐Zghoul, M. B., Zaitoun, S. T., Al-Omary, I. M., & Alahmad, N. A. (2022) · Journal of Thermal Biology · doi:10.1016/j.jtherbio.2022.103194 · Cited by 23

Disordered C-terminal domain drives spatiotemporal confinement of RNAPII to enhance search for chromatin targets

Ling, Y. H., Ye, Z., Liang, C., Yu, C., Park, G., Corden, J. L., & Wu, C. (2024) · Nature Cell Biology · doi:10.1038/s41556-024-01382-2 · Cited by 23

Structure and alternative splicing of a heat shock transcription factor gene, MsHSF1, in Medicago sativa

He, Z., Xie, R., Zou, H., Wang, Y., Zhu, J., & Yu, G. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.10.131 · Cited by 23

Alcohols lower the threshold temperature for the maximal activation of a heat shock expression vector in the yeast Saccharomyces cerevisiae

Curran, B. P. G., & Khalawan, S. A. (1994) · Microbiology · doi:10.1099/13500872-140-9-2225 · Cited by 23

Mechanism of heat shock Protein 72 induction in primary cultured astrocytes after oxygen-glucose deprivation

Bergeron, M., Mivechi, N. F., Giaccia, A. J., & Giffard, R. G. (1996) · Neurological Research · doi:10.1080/01616412.1996.11740380 · Cited by 23

Authentic temperature-regulation of a heat shock gene inserted into yeast on a high copy number vector

Cheng, L., Hirst, K. L., & Piper, P. W. (1992) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/0167-4781(92)90048-5 · Cited by 23

Phosphorylation of Drosophila heat shock transcription factor

Fritsch, M. K., & Wu, C. (1999) · Cell Stress and Chaperones · doi:10.1054/csac.1998.0003 · Cited by 23

Transcriptional regulation of heat shock genes

Kingston, R. E. (1991) · Molecular aspects of cellular regulation · doi:10.1016/b978-0-444-81382-4.50024-4 · Cited by 23

Induction of Immediate Early and Stress Genes in Rat Proximal Tubule Epithelium Following Injury: The Significance of Cytosolic Ionized Calcium

Yamamoto, N., Maki, A., Swann, J. D., Berezesky, I. K., & Trump, B. F. (1993) · Renal Failure · doi:10.3109/08860229309046148 · Cited by 23

Heat shock factor can activate transcription while bound to nucleosomal DNA in Saccharomyces cerevisiae

Pederson, D. S., & Fidrych, T. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.1.189 · Cited by 23

Heat Stress Promoters and Transcription Factors

Scharf, K., Materna, T., Treuter, E., & Nover, L. (1994) · Results and problems in cell differentiation · doi:10.1007/978-3-540-48037-2_6 · Cited by 23

Transcriptional regulation of a yeast HSP70 gene by heat shock factor and an upstream repression site-binding factor.Preprint

Park, H.-O., & Craig, E. A. (1991) · Genes & Development · doi:10.1101/gad.5.7.1299 · Cited by 23

Cooperative binding of two E2F molecules to an Ela‐responsive promoter is triggered by the adenovirus Ela, but not by a cellular Ela‐like activity.

Jansen‐Dürr, P., Bœuf, H., & Kédinger, C. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08499.x · Cited by 23

Over-expression of LlHsfA2b, a lily heat shock transcription factor lacking trans-activation activity in yeast, can enhance tolerance to heat and oxidative stress in transgenic Arabidopsis seedlings

Xin, H., Zhang, H., Zhong, X., Lian, Q., Dong, A., Cao, L., Yi, M., & Cong, R. (2017) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-017-1251-2 · Cited by 22

Roles of Three HSF Domain-Containing Proteins in Mediating Heat-Shock Protein Genes and Sustaining Asexual Cycle, Stress Tolerance, and Virulence in Beauveria bassiana

Zhou, G., Ying, S., Hu, Y., Fang, X., Feng, M., & Wang, J. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01677 · Cited by 22

The yeast stress response

Rodrigues‐Pousada, C., Nevitt, T., & Menezes, R. (2005) · FEBS Journal · doi:10.1111/j.1742-4658.2005.04695.x · Cited by 22

Rsp5–Bul1/2 complex is necessary for the HSE-mediated gene expression in budding yeast

Kaida, D., Toh‐e, A., & Kikuchi, Y. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)01090-8 · Cited by 22

Stress responses

Dawes, I. W. (2004) · CRC Press eBooks · doi:10.1201/9780203503867.ch9 · Cited by 22

Proline in α‐helical kink is required for folding kinetics but not for kinked structure, function, or stability of heat shock transcription factor

Hardy, J. A., & Nelson, H. C. M. (2000) · Protein Science · doi:10.1110/ps.9.11.2128 · Cited by 22

Development of acute thermotolerance in 1929 cells: Lack of HSP28 synthesis and phosphorylation

Lee, Y. J., Hou, Z., Curetty, L., & Borrelli, M. J. (1992) · Journal of Cellular Physiology · doi:10.1002/jcp.1041520116 · Cited by 22

Phosphorylation of immunopurified rat liver glucocorticoid receptor by the catalytic subunit of cAMP-dependent protein kinase

Haske, T., Nakao, M., & Moudgil, V. K. (1994) · Molecular and Cellular Biochemistry · doi:10.1007/bf00926925 · Cited by 24

The Heat Shock Transcription Factor HsfA Plays a Role in Membrane Lipids Biosynthesis Connecting Thermotolerance and Unsaturated Fatty Acid Metabolism in Aspergillus fumigatus

Fabri, J. H. T. M., Rocha, M. C., Fernandes, C. M., Campanella, J. E. M., da Cunha, A. F., Poeta, M. D., & Malavazi, I. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.01627-23 · Cited by 21

A quantitative and temporal map of proteostasis during heat shock in Saccharomyces cerevisiae

Jarnuczak, A. F., Albornoz, M. G., Eyers, C. E., Grant, C. M., & Hubbard, S. J. (2018) · Molecular Omics · doi:10.1039/c7mo00050b · Cited by 21

A Rapid Method to Determine the Stress Status of Saccharomyces cerevisiae by Monitoring the Expression of a Hsp12:Green Fluorescent Protein (GFP) Construct under the Control of the Hsp12 Promoter

Karreman, R. J., & Lindsey, G. G. (2005) · SLAS DISCOVERY · doi:10.1177/1087057104273485 · Cited by 21

Translational readthrough at nonsense mutations in the HSF1 gene of Saccharomyces cerevisme

Kopczynski, J. B., Raff, A. C., & Bonner, J. J. (1992) · Molecular and General Genetics MGG · doi:10.1007/bf00538696 · Cited by 21

Differential HSC70 expression during asexual development of Neurospora crassa

Fracella, F., Scholle, C., Kallies, A., Häfker, T., Schröder, T., & Rensing, L. (1997) · Microbiology · doi:10.1099/00221287-143-11-3615 · Cited by 21

Enhanced phosphorylation of a 65 kDa protein is associated with rapid induction of stress proteins in 9L rat brain tumor cells

Lai, Y., Shen, C., Cheng, T.-J. R., Hou, M., & Lee, W. (1993) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240510317 · Cited by 21

Structural Organization and Promoter Analysis of Murine Heat Shock Transcription Factor-1 Gene

Zhang, Y., Koushik, S. V., Dai, R., & Mivechi, N. F. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.49.32514 · Cited by 21

Heat shock factor 1 regulates heat shock proteins and immune-related genes in Penaeus monodon under thermal stress

Sornchuer, P., Junprung, W., Yingsunthonwattana, W., & Tassanakajon, A. (2018) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2018.06.013 · Cited by 20

Isolation and Characterization of a cDNA Encoding Two Novel Heat-shock Factor OsHSF6 and OsHSF12 in Oryza Sativa L.

Liu, J., Yao, Q., Zhang, Z., Peng, R., Xiong, A., Xu, F., & Zhu, H. (2005) · BMB Reports · doi:10.5483/bmbrep.2005.38.5.602 · Cited by 20

Heat Shock Transcription Factor 1 Is Activated as a Consequence of Lymphocyte Activation and Regulates a Major Proteostasis Network in T Cells Critical for Cell Division During Stress

Gandhapudi, S. K., Murapa, P., Threlkeld, Z. D., Ward, M. R., Sarge, K. D., Snow, C., & Woodward, J. G. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1202831 · Cited by 21

Structural analysis of yeast HSF by site-specific crosslinking

Bonner, J. J., Chen, D. J., Storey, K., Tushan, M., & Lea, K. (2000) · Journal of Molecular Biology · doi:10.1006/jmbi.2000.4096 · Cited by 20

Genome-wide characterization and expression analysis of the heat shock transcription factor family in pumpkin (Cucurbita moschata)

Shen, C., & Yuan, J. (2020) · BMC Plant Biology · doi:10.1186/s12870-020-02683-y · Cited by 20

Human aging alters the first phase of the molecular response to stress in T-cells

Jurivich, D. A., Choo, M., Welk, J. F., Qiu, L., Han, K., & Zhou, X. (2005) · Experimental Gerontology · doi:10.1016/j.exger.2005.08.003 · Cited by 20

A Novel Domain of the Yeast Heat Shock Factor That Regulates Its Activation Function

Sakurai, H., & Fukasawa, T. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5234 · Cited by 20

Proteasome Inhibitors Lactacystin and MG132 Inhibit the Dephosphorylation of HSF1 after Heat Shock and Suppress Thermal Induction of Heat Shock Gene Expression

Kim, D., & Li, G. C. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1371 · Cited by 20

Characterization of a new member of the sea urchin Paracentrotus lividus hsp70 gene family and its expression

Sconzo, G., Scardina, G. A., & Ferraro, M. G. (1992) · Gene · doi:10.1016/0378-1119(92)90143-d · Cited by 20

Analysis of the Mammalian Heat-Shock Response: Inducible Gene Expression and Heat-Shock Factor Activity

Mathew, A., Shi, Y., Jolly, C., & Morimoto, R. I. (2003) · Humana Press eBooks · doi:10.1385/1-59259-054-3:217 · Cited by 20

Protein Post-Translational Modifications in Plant Abiotic Stress Responses

Li, G., Feng, B., Zhu, Q., Jiang, K., & Zhang, T. (2025) · Plants · doi:10.3390/plants15010052 · Cited by 19

Deteriorated Stress Response in Stationary-Phase Yeast: Sir2 and Yap1 Are Essential for Hsf1 Activation by Heat Shock and Oxidative Stress, Respectively

Nussbaum, I., Weindling, E., Jubran, R., Cohen, A., & Bar‐Nun, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111505 · Cited by 23

Construction of Light-Responsive Gene Regulatory Network for Growth, Development and Secondary Metabolite Production in Cordyceps militaris

In-on, A., Thananusak, R., Ruengjitchatchawalya, M., Vongsangnak, W., & Laomettachit, T. (2022) · Biology · doi:10.3390/biology11010071 · Cited by 19

HSF1 and Its Role in Huntington’s Disease Pathology

Kim, H., & Gómez‐Pastor, R. (2022) · Advances in experimental medicine and biology · doi:10.1007/5584_2022_742 · Cited by 21

Function of the C-terminal transactivation domain of human heat shock factor 2 is modulated by the adjacent negative regulatory segment

Yoshima, T. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.11.2580 · Cited by 19

Heat-Shock Proteins: a Search for Functions

Harrington, H. M., Dash, S., Dharmasiri, N., & Dharmasiri, S. (1994) · Australian Journal of Plant Physiology · doi:10.1071/pp9940843 · Cited by 19

Genome-wide identification and functional analyses of heat shock transcription factors involved in heat and drought stresses in ryegrass

Ma, G., Shen, J., Yu, H. T., Huang, X., Deng, X., Hu, Z., Amee, M., Chen, L., & Cao, L. (2022) · Environmental and Experimental Botany · doi:10.1016/j.envexpbot.2022.104968 · Cited by 18

Genetic Selection for Constitutively Trimerized Human HSF1 Mutants Identifies a Role for Coiled-Coil Motifs in DNA Binding

Neef, D. W., Jaeger, A. M., & Thiele, D. J. (2013) · G3 Genes Genomes Genetics · doi:10.1534/g3.113.006692 · Cited by 18

Manipulation of protein kinases reveals different mechanisms for upregulation of heat shock proteins in motor neurons and non-neuronal cells

Taylor, D. M., Koninck, P. D., Minotti, S., & Durham, H. D. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2006.09.007 · Cited by 18

Mutations that affect phosphorylation of the adenovirus DNA-binding protein alter its ability to enhance its own synthesis

Morin, N., Delsert, C., & Klessig, D. F. (1989) · Journal of Virology · doi:10.1128/jvi.63.12.5228-5237.1989 · Cited by 18

Activation of simian virus 40 transcription in vitro by T antigen

Coulombe, J. V., Berger, L., Smith, D. B., Hehl, R. K., & Wildeman, A. G. (1992) · Journal of Virology · doi:10.1128/jvi.66.7.4591-4596.1992 · Cited by 17

Expansion of the HSP70 gene family in Tegillarca granosa and expression profiles in response to zinc toxicity

Kim, J., Kim, H. J., Choi, E., Cho, M., Choi, S., Jeon, M. A., Lee, J. S., & Park, H. (2024) · Cell Stress and Chaperones · doi:10.1016/j.cstres.2024.01.004 · Cited by 16

Radiosensitization of HSF-1 Knockdown Lung Cancer Cells by Low Concentrations of Hsp90 Inhibitor NVP-AUY922

Kühnel, A., Schilling, D., Combs, S. E., Haller, B., Schwab, M., & Multhoff, G. (2019) · Cells · doi:10.3390/cells8101166 · Cited by 16

Stress Responses inCandida

Brown, A. J. P., Haynes, K., Gow, N. A. R., & Quinn, J. (2014) · ASM Press eBooks · doi:10.1128/9781555817176.ch15 · Cited by 16

Galactose-induced puffing changes inChironomus thummi Balbiani rings and their dependence on protein synthesis

Díez, J. L., Cortés, E., Merino, Y., & Santa‐Cruz, M. C. (1990) · Chromosoma · doi:10.1007/bf01737290 · Cited by 16

Enhancer function in viral and cellular gene regulation

Marriott, S. J., & Brady, J. N. (1989) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/0304-419x(89)90037-1 · Cited by 16

Insulin induces the phosphorylation of DNA-binding nuclear proteins including lamins in 3T3-F442A

Csermely, P., & Kahn, C. R. (1992) · Biochemistry · doi:10.1021/bi00156a012 · Cited by 16

Reprogramming of Gene Expression After Ischemia

Nowak, T. S., & Kiessling, M. (1999) · Humana Press eBooks · doi:10.1007/978-1-59259-479-5_7 · Cited by 16

Identification of HSF1 Target Genes Involved in Thermal Stress in the Pacific Oyster Crassostrea gigas by ChIP-seq

Liu, Y., Zhu, Q., Li, A., Wang, W., & Zhang, G. (2020) · Marine Biotechnology · doi:10.1007/s10126-019-09942-6 · Cited by 15

Glucocorticoid Receptor and Heat Shock Factor 1: Novel Mechanism of Reciprocal Regulation

Li, D., & Sánchez, E. R. (2005) · Vitamins and hormones · doi:10.1016/s0083-6729(05)71008-6 · Cited by 15

Genome-wide identification and analysis of heat shock transcription factor family in cucumber (Cucumis sativus L.).

Zhou, S., Zhang, P., Jing, Z., & Shi, J. (2013) · Plant Omics · Cited by 15

Heat shock transcriptional factor mediates mitochondrial unfolded protein response

Koike, N., Hatano, Y., & Ushimaru, T. (2018) · Current Genetics · doi:10.1007/s00294-018-0809-9 · Cited by 15

HSP70 expression is increased during the day in a diurnal animal, the golden-mantled ground squirrelSpermophilus lateralis

Bitting, L., Watson, F. L., O’Hara, B. F., Kilduff, T. S., & Heller, H. C. (1999) · Molecular and Cellular Biochemistry · doi:10.1023/a:1006942814185 · Cited by 15

Nodule-Specific Kinases Phosphorylating Nuclear Factors in Isolated Nuclei

Suzuki, H., & Verma, D. P. S. (1989) · The Plant Cell · doi:10.1105/tpc.1.3.373 · Cited by 15

A kinase that responds to stress

Sweet, D. J. (1993) · Current Biology · doi:10.1016/0960-9822(93)90014-f · Cited by 15

Deletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress

Mühlhofer, M., Offensperger, F., Reschke, S., Wallmann, G., Csaba, G., Berchtold, E., Riedl, M., Blum, H., Haslbeck, M., Zimmer, R., et al. (2024) · FEBS Letters · doi:10.1002/1873-3468.14821 · Cited by 14

Knocking down gene function with an RNA aptamer expressed as part of an intron

Wang, S., Zhao, X., Suran, R., Vogt, V. M., Lis, J. T., & Shi, H. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq529 · Cited by 14

Use of suppressor analysis to find genes involved in the colonization deficiency of a Bacteroides thetaiotaomicron mutant unable to grow on the host-derived mucopolysaccharides chondroitin sulfate and heparin

Cheng, Q., & Salyers, A. A. (1995) · Applied and Environmental Microbiology · doi:10.1128/aem.61.2.734-740.1995 · Cited by 14

The DNA-binding domain of yeast Hsf1 regulates both DNA-binding and transcriptional activities

Yamamoto, A., & Sakurai, H. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.06.057 · Cited by 14

Effects of Heat Stress on Yeast Heat Shock Factor-Promoter Binding In Vivo

Li, N., Zhang, L., Zhang, K., Deng, J.-S., Prändl, R., & Schöffl, F. (2006) · Acta Biochimica et Biophysica Sinica · doi:10.1111/j.1745-7270.2006.00170.x · Cited by 11

Constitutive Binding of Yeast Heat Shock Factor to DNA In Vivo

Jakobsen, B. K., & Pelham, H. R. B. (1988) · Molecular and Cellular Biology · doi:10.1128/mcb.8.11.5040 · Cited by 222

34 Heat Shock FactorPreprint

Lis, J. T., & Wu, C. (1992) · Cold Spring Harbor Monograph Archive · doi:10.1101/087969425.22b.907

Yeast heat shock factor contains separable transient and sustained response transcriptional activators

Sorger, P. K. (1990) · Cell · doi:10.1016/0092-8674(90)90123-v · Cited by 241

Heat shock factor is regulated differently in yeast and HeLa cells

Sorger, P. K., Lewis, M. J., & Pelham, H. R. B. (1987) · Nature · doi:10.1038/329081a0 · Cited by 443