Endothelial inflammation in insulin resistance
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The anti-inflammatory activities of PPARs are partially effectuated by inhibition of NF-κB; PPARα impairs binding of NF-κB to DNA and increases expression of IκB.
“The anti-inflammatory activities of PPARs are partially effectuated by inhibition of NF-κB. PPARs are able to attenuate NF-κB function either by interfering with the transcription activating capacity of the NF-κB complex or by regulating genes that suppress the activation of NF-κB. By physical interaction with components of the NF-κB complex, PPARα impairs binding of NF-κB to the DNA and”
From Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review (2010) · cites this paper as [135]
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Maternal lipid levels in preeclampsia: singleton vs. twin pregnancies
Wang, J., Gu, X., Yang, J., et al. (2021) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2021.1907335 · Cited by 7 · see citing works
- Authors
- SJOHOLM, A., & NYSTROM, T.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2005-02-18
- Volume
- 365
- Issue
- 9459
- Pages
- 610-612
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2161477191
- Cited by
- 278
- References
- 0
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 7 · 2023: 9 · 2022: 7 · 2021: 7 · 2019: 6 · 2018: 5 · 2017: 4 · 2016: 6 · 2015: 7 · 2014: 8 · 2013: 8 · 2012: 15
- FWCI
- 5.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
- Life Sciences › Immunology and Microbiology › Immunology › Biomarkers in Disease Mechanisms
- Keywords
- endothelial inflammation, insulin resistance, type 2 diabetes, C-reactive protein, endothelial progenitor cells, endothelial nitric oxide synthase, rosiglitazone, atherosclerosis, atherothrombosis, metabolic syndrome, obesity, cardiovascular risk
- MeSH terms
- Arteriosclerosis, C-Reactive Protein, Diabetes Mellitus, Type 2, Endothelium, Vascular, Humans, Inflammation, Insulin Resistance, Biomarkers, Inflammation Mediators, Metabolic Syndrome
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