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Endothelial inflammation in insulin resistance
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“The anti-inflammatory activities of PPARs are partially effectuated by inhibition of NF-κB. PPARs are able to attenuate NF-κB function either by interfering with the transcription activating capacity of the NF-κB complex or by regulating genes that suppress the activation of NF-κB. By physical interaction with components of the NF-κB complex, PPARα impairs binding of NF-κB to the DNA and”
From Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review (2010) · cites this paper as [135]
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Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review
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“Secondly, PPARα activation results in increased expression of IκB, the inhibitory protein that prevents the transfer of NF-κB to the nucleus [134,135].”
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Metadata
- Authors
- SJOHOLM, A., & NYSTROM, T.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2005-02-18
- Volume
- 365
- Issue
- 9459
- Pages
- 610-612
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2161477191
- Cited by
- 278
- References
- 0
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 7 · 2023: 9 · 2022: 7 · 2021: 7 · 2019: 6 · 2018: 5 · 2017: 4 · 2016: 6 · 2015: 7 · 2014: 8 · 2013: 8 · 2012: 15
- FWCI
- 5.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Life Sciences › Immunology and Microbiology › Immunology › Biomarkers in Disease Mechanisms
- Keywords
- endothelial inflammation, insulin resistance, type 2 diabetes, C-reactive protein, endothelial progenitor cells, endothelial nitric oxide synthase, rosiglitazone, atherosclerosis, atherothrombosis, metabolic syndrome, obesity, cardiovascular risk
- MeSH terms
- Arteriosclerosis, C-Reactive Protein, Diabetes Mellitus, Type 2, Endothelium, Vascular, Humans, Inflammation, Insulin Resistance, Biomarkers, Inflammation Mediators, Metabolic Syndrome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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