The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Greatly increased luminal nitric oxide in ulcerative colitis
Abstract
A role for nitric oxide (NO) in ulcerative colitis has been suggested because mucosal NO synthase activity, measured by indirect assays, is increased in this disorder. We directly measured luminal NO in the colons of twelve controls and six patients with active ulcerative colitis. During colonoscopy, gas was aspirated from different parts of the colon and immediately analysed by a chemiluminescence technique. NO concentrations were more than 100 times higher in the patients than in the controls. Luminal NO is rapidly and easily measurable and may be used to monitor inflammatory bowel disease.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“This shift is particularly notable in the context of inflammatory bowel disease, where massive blooms of pathogenic, nitrate-reducing Salmonella and Escherichia coli are seen in response to inflammation[333,334,338,339].”
From Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health (2017) · cites this paper as [339]
In the citing paper
“which is then reduced to nitrite by commensal anaerobic bacteria on the tongue [22].”
From NO-Rich Diet for Lifestyle-Related Diseases (2015) · cites this paper as [22]
In the citing paper
“However, chronic inflammation, including inflammatory bowel disease and Helicobacter pylori-induced gastritis induce inducible NOS (iNOS) and generate large quantities of NO [22,146,147], forming nitrosating and oxidant species such as N2O3 and peroxynitrite, which might cause mutagenesis through deamination, nitration of DNA, or inhibition of the DNA repair system [148,149].”
From NO-Rich Diet for Lifestyle-Related Diseases (2015) · cites this paper as [22]
In the citing paper
“Acidic disproportionation of nitrite can lead to increased levels of NO [84–86].”
From Inorganic nitrite therapy: historical perspective and future directions (2011) · cites this paper as [86]
Citations
Cites
Nitric oxide: physiology, pathophysiology, and pharmacology.
Moncada, S., Palmer, R. M., & Higgs, E. A. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06663-3 · Cited by 15,525
Increased amount of nitric oxide in exhaled air of asthmatics
Alving, K., Weitzberg, E., & Lundberg, J. (1993) · European Respiratory Journal · doi:10.1183/09031936.93.06091368 · Cited by 1,232
Self-citationIntragastric nitric oxide production in humans: measurements in expelled air.
Lundberg, J. O., Weitzberg, E., Lundberg, J. M., & Alving, K. (1994) · Gut · doi:10.1136/gut.35.11.1543 · Cited by 661
Self-citationNitric oxide synthase activity in ulcerative colitis and Crohn's disease
Boughton-Smith, N. K., Evans, S., Whittle, B. J. R., Moncada, S., Hawkey, C. J., COLE, A. T., & Balsitis, M. (1993) · The Lancet · doi:10.1016/0140-6736(93)91476-3 · Cited by 459
Primarily nasal origin of exhaled nitric oxide and absence in Kartagener's syndrome
Lundberg, J., Weitzberg, E., Nordvall, S. L., Kuylenstierna, R., Jm, L., & Alving, K. (1994) · European Respiratory Journal · doi:10.1183/09031936.94.07081501 · Cited by 408
Self-citationIncreased nitric oxide synthesis in ulcerative colitis
Middleton, S. J., Shorthouse, M., & Hunter, J. O. (1993) · The Lancet · doi:10.1016/0140-6736(93)90211-x · Cited by 343
Nitric oxide synthase induction and intestinal epithelial cell viability in rats
Tepperman, B. L., Brown, J. F., & Whittle, B. J. R. (1993) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1993.265.2.g214 · Cited by 194
The rectal mucosa-associated microflora in patients with ulcerative colitis
Hartley, M. G., HUDSON, M. J., Swarbrick, E. T., Hill, M. J., Gent, A. E., Hellier, M. D., & Grace, R. H. (1992) · Journal of Medical Microbiology · doi:10.1099/00222615-36-2-96 · Cited by 80
Research works printed but not linked: 1
- Ji, 1989, Nitrate reductase of Escherichia coli as a NO-producing nitrite reductase, Biochem Arch, 5, 61
Cited by
Sorted by citations
Items 101–200 of 266
Dudhgaonkar, S. P., Tandan, S. K., Kumar, D., Raviprakash, V., & Kataria, M. (2007) · Inflammopharmacology · doi:10.1007/s10787-007-1603-3 · Cited by 51
Kitabatake, M., Matsumura, Y., Ouji-Sageshima, N., Nishioka, T., Hara, A., Kayano, S.-I., & Ito, T. (2021) · Scientific Reports · doi:10.1038/s41598-021-86608-1 · Cited by 52
Change of nitric oxide in experimental colitis and its inhibition by melatonin in vivo and in vitro
Mei, Q., Xu, J.-M., Li, X., Hu, Y.-M., Hu, X.-P., & Xu, Z.-W. (2005) · Postgraduate Medical Journal · doi:10.1136/pgmj.2004.030817 · Cited by 52
Koek, G. H., Verleden, G. M., Evenepoel, P., & Rutgeerts, P. (2002) · Respiratory Medicine · doi:10.1053/rmed.2002.1312 · Cited by 50
Hellström, P. M., Al‐Saffar, A., Ljung, T., & Theodorsson, E. (1997) · Digestive Diseases and Sciences · doi:10.1023/a:1018897028463 · Cited by 50
Self-citationInduction of iNOS in a Rat Model of Acute Colitis
Kankuri, E. M., Asmawi, M. Z., Korpela, R., Vapaatalo, H., & Moilanen, E. (1999) · Inflammation · doi:10.1023/a:1020241028723 · Cited by 49
Rabbi, M. F., Eissa, N., Munyaka, P. M., Kermarrec, L., Elgazzar, O., Khafipour, E., Bernstein, C. N., & Ghia, J. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00985 · Cited by 48
Rachmilewitz, D., Eliakim, R., Ackerman, Z., & Karmeli, F. (1998) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1998.00409.x · Cited by 49
Interleukin-1 production by mouse macrophages is regulated in a feedback fashion by nitric oxide
Obermeier, F., Groß, V., Schölmerich, J., & Falk, W. (1999) · Journal of Leukocyte Biology · doi:10.1002/jlb.66.5.829 · Cited by 48
Nitric oxide mediates a therapeutic effect of nicotine in ulcerative colitis
Green, J. T., Richardson, C., Marshall, R. W., Rhodes, J., McKirdy, H. C., Thomas, G. A. O., & Williams, G. T. (2000) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2000.00847.x · Cited by 48
Increased Nitric Oxide in Infective Gastroenteritis
Herulf, M., Svenungsson, B., Lagergren, Å., Ljung, T., Morcos, E., Wiklund, N. P., Lundberg, J. O. N., & Weitzberg, E. (1999) · The Journal of Infectious Diseases · doi:10.1086/314908 · Cited by 48
Self-citationRezaie, A. R., Khalaj, S., Shabihkhani, M., Nikfar, S., Zamani, M. J., Mohammadirad, A., Daryani, N. E., & Abdollahi, M. R. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1397.034 · Cited by 47
eNOS involved in colitis-induced mucosal blood flow increase
Petersson, J. H., Schreiber, O., Steege, A., Patzak, A. R., Hellsten, A., Phillipson, M., & Holm, L. P. (2007) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00357.2007 · Cited by 44
Rectal Nitric Oxide Gas and Stool Cytokine Levels during the Course of Infectious Gastroenteritis
Enocksson, A., Lundberg, J. O., Weitzberg, E., Norrby‐Teglund, A., & Svenungsson, B. (2004) · Clinical and Vaccine Immunology · doi:10.1128/cdli.11.2.250-254.2004 · Cited by 45
Self-citationWang, H., Zhang, R., Wen, S., McCafferty, D., Beck, P. L., & MacNaughton, W. K. (2009) · Journal of Molecular Medicine · doi:10.1007/s00109-009-0445-4 · Cited by 46
Nitrogen Dioxide, the Oxides of Nitrogen, and Infants' Health Symptoms
Farrow, A., Greenwood, R., Preece, S., & Golding, J. (1997) · Archives of Environmental Health An International Journal · doi:10.1080/00039899709602885 · Cited by 45
Nitrate-Reducing Bacteria in Diversion Colitis (A Clue to Inflammation?)
Neut, C., Guillemot, F., & Colombel, J. (1997) · Digestive Diseases and Sciences · doi:10.1023/a:1018885217154 · Cited by 43
Stecher, B. (2015) · ASM Press eBooks · doi:10.1128/9781555818883.ch14 · Cited by 44
Oxidants, Transcription Factors, and Intestinal Inflammation
Jourd’heuil, D., Morise, Z., Conner, E. M., & Grisham, M. B. (1997) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-199700001-00011 · Cited by 41
Choi, S.-H., Eom, J., Kim, H., Seo, W., Kwun, H., Kim, D., Kim, J., & Cho, Y. (2023) · Biomaterials Science · doi:10.1039/d3bm00591g · Cited by 42
Calpain inhibitor I reduces colon injury caused by dinitrobenzene sulphonic acid in the rat
Cuzzocrea, S., McDonald, M. C., Mazzon, E., Mota‐Filipe, H., Centorrino, T., Terranova, M. L., Ciccolo, A., Britti, D., Caputi, A. P., & Thiemermann, C. (2001) · Gut · doi:10.1136/gut.48.4.478 · Cited by 41
NITRIC OXIDE: A USEFUL GAS IN THE DETECTION OF LOWER URINARY TRACT INFLAMMATION
Ehrén, I., Hosseini, A., Lundberg, J. O., & Wiklund, P. N. (1999) · The Journal of Urology · doi:10.1016/s0022-5347(05)68551-5 · Cited by 40
Self-citationRectal nitric oxide and fecal calprotectin in inflammatory bowel disease
Reinders, C. I., Jonkers, D. M. A. E., Jansson, E. Å., Stockbrügger, R. W., Stobberingh, E. E., Hellström, P. M., & Lundberg, J. O. (2007) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520701320505 · Cited by 39
Self-citationPerner, A., Nordgaard, I., Matzen, P., & Rask-Madsen, J. (2002) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655202753416858 · Cited by 39
Aiko, S., Fuseler, J. W., & Grisham, M. B. (1998) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37281-7 · Cited by 39
Genetically Encoded Fluorescent Biosensors for Biomedical Applications
Ovechkina, V. S., Zakian, S. M., Medvedev, S. P., & Valetdinova, K. R. (2021) · Biomedicines · doi:10.3390/biomedicines9111528 · Cited by 42
Tučková, L., Flegelová, Z., Tlaskalová‐Hogenová, H., & Zı́dek, Z. (2000) · Journal of Leukocyte Biology · doi:10.1002/jlb.67.3.312 · Cited by 38
Ehrén, I., Lundberg, J. O., Adolfsson, J., & Wiklund, P. N. (1998) · Urology · doi:10.1016/s0090-4295(98)00343-4 · Cited by 37
Self-citationEnterococcus faecalis EF-2001 protects DNBS-induced inflammatory bowel disease in mice model
Choi, E., Lee, H. J., Kim, W.-J., Han, K.-I., Iwasa, M., Kobayashi, K., Debnath, T., Tang, Y., Kwak, Y., Yoon, J.-H., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0210854 · Cited by 36
Development of Cell-Based Sentinels for Nitric Oxide: Ensuring Marker Expression and Unimodality
McKay, R., Hauk, P., Quan, D. N., & Bentley, W. E. (2018) · ACS Synthetic Biology · doi:10.1021/acssynbio.8b00146 · Cited by 35
Nitric oxide synthesis in patients with infective gastroenteritis
Forte, P., Dykhuizen, R. S., Milne, E., McKenzie, A., Smith, C. C., & Benjamin, N. (1999) · Gut · doi:10.1136/gut.45.3.355 · Cited by 35
Schubert, C., & Unden, G. (2022) · Journal of Bacteriology · doi:10.1128/jb.00545-21 · Cited by 32
Small therapeutic molecules for the treatment of inflammatory bowel disease
van Deventer, S. J. H. (2002) · Gut · doi:10.1136/gut.50.suppl_3.iii47 · Cited by 34
Synthetic bacterial therapies for intestinal diseases based on quorum-sensing circuits
Dang, Z., Gao, M., Wang, L., Wu, J., Guo, Y., Zhu, Z., Huang, H., & Kang, G. (2023) · Biotechnology Advances · doi:10.1016/j.biotechadv.2023.108142 · Cited by 36
Microbiota-nourishing Immunity and Its Relevance for Ulcerative Colitis
Byndloss, M. X., Litvak, Y., & Bäumler, A. J. (2019) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izz004 · Cited by 33
Gut redox and microbiome: charting the roadmap to T-cell regulation
Prasad, S., Singh, S., Menge, S., Mohapatra, I., Kim, S., Helland, L. C., Singh, G., & Singh, A. R. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1387903 · Cited by 35
Özyılmaz, E., Yıldırım, B., Erbaş, G., Akten, S., Oguzulgen, K. I., Tunç, B., Tunçer, C., & Türktaş, H. (2009) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21085 · Cited by 32
Kefir treatment ameliorates dextran sulfate sodium-induced colitis in rats
Şenol, A. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i46.13020 · Cited by 31
In Vivo Imaging of Reactive Oxygen and Nitrogen Species in Murine Colitis
Asghar, M. N., Emani, R., Alam, C. M., Helenius, T. O., Grönroos, T. J., Sareila, O., U-Din, M., Holmdahl, R., Hänninen, A. L. M., & Toivola, D. M. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000118 · Cited by 30
Prediction of nitric oxide concentrations in colonic crypts during inflammation
Chin, M. P., Schauer, D. B., & Deen, W. M. (2008) · Nitric Oxide · doi:10.1016/j.niox.2008.04.025 · Cited by 29
The effect of α-melanocyte stimulating hormone on colonic inflammation in the rat
Oktar, B. K., Ercan, F., Yeğen, B. Ç., & Ali̇can, İ. (2000) · Peptides · doi:10.1016/s0196-9781(00)00269-2 · Cited by 30
Khajah, M. A., Orabi, K. Y., Hawai, S., Sary, H. G., & El‐Hashim, A. Z. (2019) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2019.112008 · Cited by 29
Nitric Oxide Prevents Anoxia-Induced Apoptosis in Colonic HT29 Cells
Madesh, M., Ramachandran, A., & Balasubramanian, K. A. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1185 · Cited by 29
Ehrén, I., Hallén, K., Vrba, M., Sundelin, R., & Lafolie, P. (2013) · Scandinavian Journal of Urology · doi:10.3109/21681805.2013.788552 · Cited by 26
Linehan, J. D., Kolios, G. C., Valatas, V., Robertson, D. A., & Westwick, J. K. (2004) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00336.2004 · Cited by 26
Spillare, E. A., Okamoto, A., Hagiwara, K., Demetrick, D. J., Serrano, M., Beach, D., & Harris, C. C. (1996) · Molecular Carcinogenesis · doi:10.1002/(sici)1098-2744(199605)16:1 · Cited by 36
Acid-resistant chemotactic DNA micromotors for probiotic delivery in inflammatory bowel disease
Zhao, Z., Xu, Y., & Hu, Y. M. (2025) · Nature Communications · doi:10.1038/s41467-025-59172-9 · Cited by 28
Zı́dek, Z., & Mašek, K. (1998) · International Journal of Immunopharmacology · doi:10.1016/s0192-0561(98)00036-8 · Cited by 25
Bouin, M., Delvaux, M. M., Blanc, C., Lagier, E., Delisle, M., Fioramonti, J., Bueno, L. P., & Frexinos, J. (2001) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-200105000-00018 · Cited by 24
Exhaled NO and plasma cGMP increase after endotoxin infusion in healthy volunteers
Soop, A., Sollevi, A., Weitzberg, E., Lundberg, J. O., Palm, J., & Albert, J. (2003) · European Respiratory Journal · doi:10.1183/09031936.03.00008603 · Cited by 24
Self-citationNitric oxide induces apoptosis in a human colonic epithelial cell line, T84
Sandoval, M., Liu, X., Oliver, P., Zhang, X.-J., Clark, D. A., & Miller, M. J. S. (1995) · Mediators of Inflammation · doi:10.1155/s0962935195000391 · Cited by 24
Peterson, C. G. B., Lampinen, M., Hansson, T., Lidén, M., Hällgren, R., & Carlson, M. (2016) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365513.2016.1185145 · Cited by 23
Upregulation of cIAP2 in regenerating colonocytes in ulcerative colitis
Seidelin, J. B., Vainer, B., Andresen, L. O., & Nielsen, O. H. (2007) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-007-0517-1 · Cited by 23
Cheng, J., Ma, X., Zhang, H., Wu, X., Li, M., Ai, G., Zhan, R., Xie, J., Su, Z., & Huang, X. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113335 · Cited by 22
Biochemistry of Nitric Oxide and Peroxynitrite: Sources, Targets and Biological Implications
Aicardo, A., Martinez, D. M., Campolo, N., Bartesaghi, S., & Radí, R. (2016) · Springer eBooks · doi:10.1007/978-3-319-45865-6_5 · Cited by 21
Exhaled nitric oxide (F E NO) in non-pulmonary diseases
Bucca, C. B., Cicolin, A., Guida, G., Heffler, E. M., Brussino, L., & Rolla, G. (2012) · Journal of Breath Research · doi:10.1088/1752-7155/6/2/027104 · Cited by 21
Qu, T.-L., Wang, E., Jin, B., Li, W.-P., Liu, R.-L., & Zhao, Z.-B. (2017) · Immunopharmacology and immunotoxicology · doi:10.1080/08923973.2016.1274997 · Cited by 19
Beneficial Effects of Ropivacaine in Rat Experimental Colitis
Martinsson, T., Ljung, T., Rubio‐Terres, C., & Hellström, P. M. (1999) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)35150-x · Cited by 21
Self-citation5-Aminoisoquinolinone reduces colon injury by experimental colitis
Cuzzocrea, S., Mazzon, E., Paola, R. D., Genovese, T., Patel, N. S. A., Muià, C., Threadgill, M. D., Sarro, A. D., & Thiemermann, C. (2004) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-004-1002-x · Cited by 20
Intracolonic Release of Nitric Oxide During Trinitrobenzene Sulfonic Acid Rat Colitis
Ferretti, M., Gionchetti, P., Rizzello, F., Venturi, A., Stella, P., Corti, F., Mizrahi, J., Miglioli, M., & Campieri, M. (1997) · Digestive Diseases and Sciences · doi:10.1023/a:1018897519880 · Cited by 20
Intrauterine nitric oxide in pelvic inflammatory disease
Sioutas, A., Ehrén, I., Lundberg, J. O., Wiklund, P. N., & Gemzell‐Danielsson, K. (2007) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.04.018 · Cited by 20
Self-citationHand-held nitric oxide sensor NIOX MINO®for the monitoring of respiratory disorders
Maniscalco, M., & Lundberg, J. O. (2010) · Expert Review of Respiratory Medicine · doi:10.1586/ers.10.67 · Cited by 19
Self-citationSobko, T., Norman, M., Norin, E. L., Gustafsson, L. E., & Lundberg, J. O. (2005) · Allergy · doi:10.1111/j.1398-9995.2005.00737.x · Cited by 19
Self-citationPlasma Nitrate as an Index of Nitric Oxide Formation in Patients with Acute Infectious Diseases
Åhrén, C. (1999) · Scandinavian Journal of Infectious Diseases · doi:10.1080/00365549950163879 · Cited by 19
Fibrogenesis and fibrosis in inflammatory bowel diseases: Good and bad side of same coin?
Principi, M. (2013) · World Journal of Gastrointestinal Pathophysiology · doi:10.4291/wjgp.v4.i4.100 · Cited by 18
Ljung, T. (2001) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655201750422684 · Cited by 18
Colonic epithelial cell turnover: possible implications for ulcerative colitis and cancer initiation
Seidelin, J. B. (2004) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520310005974 · Cited by 18
Everts, Stotzer, Olsson, Kilander, & Pettersson, �. (1999) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.1999.00519.x · Cited by 18
Plasma Nitrate Concentrations in Children with Infectious and Noninfectious Diarrhea
Charmandari, E., Meadows, N., Patel, M., Johnston, A. E., & Benjamin, N. (2001) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1002/j.1536-4801.2001.tb07291.x · Cited by 18
Increased Rectal Nitric Oxide in Children With Active Inflammatory Bowel Disease
Ljung, T., Beijer, E., Herulf, M., Weitzberg, E., Lundberg, J. O., Finkel, Y., & Hellström, P. M. (2002) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1002/j.1536-4801.2002.tb07631.x · Cited by 17
Self-citationExhaled Nitric Oxide as a Marker of Lung Involvement in Crohn's Disease
Malerba, M., Ragnoli, B., Buffoli, L., Radaeli, A., Ricci, C., Lanzarotto, F., & Lanzini, A. (2011) · International Journal of Immunopathology and Pharmacology · doi:10.1177/039463201102400434 · Cited by 17
ANTIOXIDANTS IN PEDIATRIC GASTROINTESTINAL DISEASE
Sokol, R. J., & Hoffenberg, E. J. (1996) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(05)70416-8 · Cited by 17
Increased Rectal Nitric Oxide in Coeliac Disease after Local Challenge with Gluten
Herulf, M., Blomquist, L., Ljung, T., Weitzberg, E., & Lundberg, J. O. (2001) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655201750065924 · Cited by 17
Self-citationComing clean on reuse of endoscopic equipment
Kozarek, R. A. (1998) · Gut · doi:10.1136/gut.42.2.155 · Cited by 17
Measurement of nitric oxide may differentiate between inflammatory and non-inflammatory prostatitis
Hosseini, A., Herulf, M., & Ehrén, I. (2006) · Scandinavian Journal of Urology and Nephrology · doi:10.1080/00365590500193379 · Cited by 16
Designing an in-vitro gas profiling system for human faecal samples
Rotbart, A., Yao, C. K., Ha, N., Chrisp, M. D., Muir, J. G., Gibson, P. R., Kalantar‐Zadeh, K., & Ou, J. Z. (2016) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2016.07.120 · Cited by 16
Rodríguez, A. C., Menchen, L. A., Lizasoaín, I., Leza, J. C., Menchén, P. L., González-Lara, V., Moro, M. Á., & Lorenzo, P. L. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.02047.x · Cited by 16
Inducible nitric oxide synthase as a potential blood-based biomarker in inflammatory bowel diseases.
Baranipour, S., Kadijani, A. A., Qujeq, D., Shahrokh, S., Haghazali, M., Mirzaei, A., & Asadzadeh‐Aghdaei, H. (2018) · Gastroenterology and hepatology from bed to bench. · Cited by 15
Short, L. C., Frey, R., & Benter, T. (2006) · Applied Spectroscopy · doi:10.1366/000370206776023241 · Cited by 15
Anti-Inflammatory Properties of the Enaminone E121 in the Dextran Sulfate Sodium (DSS) Colitis Model
Khajah, M. A., Ananthalakshmi, K. V. V., & Edafiogho, I. O. (2016) · PLoS ONE · doi:10.1371/journal.pone.0168567 · Cited by 17
Effect of intravenous L‐NMMA on nitric oxide production in collagenous colitis
Reinders, C. I., Hellström, P. M., Björk, J. A., Weitzberg, E., & Lundberg, J. O. (2004) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520310007611 · Cited by 15
Self-citationGubiani, D., Fabbretti, E., Cestnik, B., Nada Lavrač, A., & Urbančič, T. (2017) · Expert Systems with Applications · doi:10.1016/j.eswa.2017.05.026 · Cited by 14
Expression of apoptosis-related proteins in rat with induced colitis
D’Argenio, G., Farrace, M. G., Cosenza, V., Ritis, F. D., Valle, N. D., Manguso, F., & Piacentini, M. (2004) · International Journal of Colorectal Disease · doi:10.1007/s00384-004-0585-5 · Cited by 13
Leplingard, A., Brung-Lefebvre, M., Guédon, C., Savoye, G., Déchelotte, P., Lemoine, F., Lebreton, J.-P., & Lerebours, É. (2001) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(01)02511-4 · Cited by 13
Xue, Y., Hu, M., Cha, S., Xue, C., & Dong, N. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.10.012 · Cited by 13
Schmid, F., Chao, C., & Däbritz, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137287 · Cited by 11
Intestinal myofibroblasts produce nitric oxide in response to combinatorial cytokine stimulation
Wu, J., Chitapanarux, T., Chen, Y., Soon, R. K., & Yee, H. F. (2012) · Journal of Cellular Physiology · doi:10.1002/jcp.24164 · Cited by 12
Pegylated Arginine Deiminase Downregulates Colitis in Murine Models
Oz, H. S., Zhong, J., & de Villiers, W. J. S. (2012) · Mediators of Inflammation · doi:10.1155/2012/813892 · Cited by 12
Paola, R. D., Mazzon, E., Patel, N. S. A., Genovese, T., Muià, C., Thiemermann, C., Sarro, A. D., & Cuzzocrea, S. (2004) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.11.041 · Cited by 12
Ando, N., Kono, T., Iwamoto, J., Kikuchi-Utsumi, K., Yoneda, M., Karasaki, H., & Kasai, S. (1998) · Nitric Oxide · doi:10.1006/niox.1999.0205 · Cited by 12
Tonometric assessment of jejunal mucosal nitric oxide formation in anaesthetized pigs
Snygg, J., Casselbrant, Pettersson, �., Holm, M., Fändriks, L., & Åneman, A. (2000) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2000.00678.x · Cited by 12
Iwashita, E. (1998) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.1998.tb00652.x · Cited by 12
Ehrlich, A. C. (2016) · Journal of Gastroenterology Pancreatology & Liver Disorders · doi:10.15226/2374-815x/3/1/00146 · Cited by 11
Modulatory Effect of Nitric Oxide on Mast Cells During Induction of Dextran Sulfate Sodium Colitis
Videla, S., Vilaseca, J., Medina, C., Mourelle, M., Guarner, F., Salas, A., & Malagelada, J. (2006) · Digestive Diseases and Sciences · doi:10.1007/s10620-006-9409-5 · Cited by 11
Intestinal Nitric Oxide in the Normal and Endotoxemic Pig
m, R. E. M., Bj??rne, H., Oldner, A., Wanecek, M., Fredriksson, M., Lundberg, J. O., & Weitzberg, E. (2002) · Shock · doi:10.1097/00024382-200211000-00012 · Cited by 11
Self-citationTomobuchi, M., Oshitani, N., Matsumoto, T., Kitano, A., Seki, S., & Arakawa, T. (2001) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.2001.03396.x · Cited by 11
In Situ Detection of Gastrointestinal Inflammatory Biomarkers Using Electrochemical Gas Sensors
Huang, H., Ehmke, C., Steiger, C., Ballinger, I., Jiménez, M., Phan, N. V., Sun, H., Ishida, K., Kuosmanen, J. L. P., Jenkins, J. A., et al. (2022) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc48229.2022.9871468 · Cited by 10
Ljung, T., Axelsson, L. ‐., Herulf, M., Lundberg, J. O., & Hellström, P. M. (2007) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2007.03284.x · Cited by 9
Self-citationPulmonary functions in children with inflammatory bowel disease
Gut, G., Ben‐Tov, A., Lahad, A., Soferman, R., Cohen, S., Tauman, R., & Sivan, Y. (2016) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000000606 · Cited by 9
Perner, A., Andresen, L. O., Normark, M., Fischer-Hansen, B., & Rask-Madsen, J. (2005) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520510023152 · Cited by 9
Metadata
- Authors
- Lundberg, J. O. N., Lundberg, J. M., Alving, K., & Hellström, P. M.
- Affiliations
- Karolinska Institutet (SE)
- Karolinska University Hospital (SE)
- Corresponding author
- Lundberg, J.O.N.
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1994-12
- Volume
- 344
- Issue
- 8938
- Pages
- 1673-1674
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W2054157046
- Cited by
- 266
- References
- 8
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 6 · 2023: 6 · 2022: 5 · 2021: 6 · 2020: 3 · 2019: 4 · 2018: 6 · 2017: 4 · 2016: 10 · 2015: 8 · 2014: 2 · 2013: 6 · 2012: 10
- FWCI
- 5.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Health Sciences › Medicine › Pharmacology (medical) › Inflammatory mediators and NSAID effects
- Keywords
- nitric oxide, ulcerative colitis, nitric oxide synthase, inflammatory bowel disease, chemiluminescence measurement, colon, disease surveillance
- MeSH terms
- Adult, Aged, Colitis, Ulcerative, Colon, Colonoscopy, Humans, Luminescent Measurements, Middle Aged, Nitric Oxide
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
