Cited by 643Hemoglobin structure and functionMetal-Catalyzed Oxygenation MechanismsNitric Oxide and Endothelin Effects

The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.

Oxidation of nitrogen-oxides by bound dioxygen in hemoproteins

Doyle, Michael P., Hoekstra, James W.·1981·Journal of Inorganic Biochemistry

Open this paper in CoChat — free account

Abstract

Nitric oxide is unique among the higher oxides of nitrogen in its reactivity and efficiency for the oxidation of oxygen-bound hemoproteins. Dinitrogen trioxide serves as a nitric oxide donor, but dinitrogen tetroxide does not exhibit similar reactivity. Details are provided of the stoichiometric transformation through which nitric oxide is converted to nitrate with accompanying oxidation of myoglobin or hemoglobin to the corresponding iron(III) hemoprotein, including an estimate of the rate constant for nitric oxide oxidation of oxygen-associated myoglobin and the effect of unassociated oxygen on the stoichiometry and rates for nitric oxide oxidation. Evidence is presented to establish the mechanism of oxidation in the direct combination of nitric oxide with iron(II)-bound dioxygen.

Integrity signals

Registry

Crossref · 10.1016/s0162-0134(00)80291-3

Cites

24 of 24 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cooperativity in the dissociation of nitric oxide from hemoglobin.
Moore, E. G., & Gibson, Q. H. (1976) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)33557-3 · Cited by 292
Conformation, co-operativity and ligand binding in human hemoglobin
Cassoly, R., & Gibson, Q. H. (1975) · Journal of Molecular Biology · doi:10.1016/0022-2836(75)90382-4 · Cited by 259
Inorganic oxygen carriers as models for biological systems
McLendon, G. L., & Martell, A. E. (1976) · Coordination Chemistry Reviews · doi:10.1016/s0010-8545(00)80403-8 · Cited by 225
Absorption spectra and reaction kinetics of NO2, N2O3, and N2O4 in aqueous solution
Treinin, A., & Hayon, E. (1970) · Journal of the American Chemical Society · doi:10.1021/ja00723a001 · Cited by 221
Pulsradiolytische Beobachtungen über die Reduktion des NO3−‐Ions und über Bildung und Zerfall der persalpetrigen Säure in wäßriger Lösung
Grätzel, M., Henglein, A., & Taniguchi, S. (1970) · Berichte der Bunsengesellschaft für physikalische Chemie · doi:10.1002/bbpc.19700740322 · Cited by 189
Interaction of Nitrous Acid with Hydrogen Peroxide and with Water
Anbar, M., & Taube, H. (1954) · Journal of the American Chemical Society · doi:10.1021/ja01653a007 · Cited by 179
Pulsradiolytische Untersuchung einiger Elementarprozesse der Oxydation und Reduktion des Nitritions
Grätzel, M., Henglein, A., Lilie, J., & Beck, G. (1969) · Berichte der Bunsengesellschaft für physikalische Chemie · doi:10.1002/bbpc.19690730707 · Cited by 166
SPECTROPHOTOMETRIC STUDIES
Austin, J. H., & Drabkin, D. L. (1935) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)74966-1 · Cited by 156
The higher oxides of nitrogen: Inhalation toxicology
Guidotti, T. L. (1978) · Environmental Research · doi:10.1016/0013-9351(78)90125-1 · Cited by 138
The mechanisms of hemoglobin autoxidation evidence for proton-assisted nucleophilic displacement of superoxide by anions
Wallace, W. J., Maxwell, J. C., & Caughey, W. S. (1974) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(74)90810-9 · Cited by 120

Show all 24 references

Research works printed but not linked: 3

Azoulay, 1978, Toxicol. Europ. Res., 1, 7
Ehrman, 1972, Am. Indust. Hygiene Assoc. J., 751
Challis, 1979, J. C. S., Perkin Trans. I, 299

Sorted by citations

Items 101–200 of 641

Kinetics of Nitric Oxide Dissociation from Five- and Six-Coordinate Nitrosyl Hemes and Heme Proteins, Including Soluble Guanylate Cyclase
Kharitonov, V. G., Sharma, V. S., Magde, D., & Koesling, D. (1997) · Biochemistry · doi:10.1021/bi970201o · Cited by 171
Modulation of nitric oxide bioavailability by erythrocytes
Huang, K., Han, T. H., Hyduke, D. R., Vaughn, M. W., Herle, H. M.-L. V., Hein, T. W., Zhang, C., Kuo, L., & Liao, J. C. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.201276698 · Cited by 172
Mechanisms of Reductive Nitrosylation in Iron and Copper Models Relevant to Biological Systems
Ford, P. C., Fernandez, B. O., & Lim, M. D. (2005) · Chemical Reviews · doi:10.1021/cr0307289 · Cited by 169
Half-life of nitric oxide in aqueous solutions with and without haemoglobin
HAKIM, T. S., Sugimori, K., Camporesi, E. M., & Anderson, G. (1996) · Physiological Measurement · doi:10.1088/0967-3334/17/4/004 · Cited by 168
Nitric oxide complexes of metalloporphyrins: an overview of some mechanistic studies
Hoshino, M., Laverman, L. E., & Ford, P. C. (1999) · Coordination Chemistry Reviews · doi:10.1016/s0010-8545(98)00228-8 · Cited by 168
The Physiological and Pathological Chemistry of Nitric Oxide
Beckman, J. S. (1996) · Elsevier eBooks · doi:10.1016/b978-012435555-2/50002-4 · Cited by 168
Erythrocytes and Vascular Function: Oxygen and Nitric Oxide
Helms, C. C., Gladwin, M. T., & Kim‐Shapiro, D. B. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00125 · Cited by 173
The Nitric Oxide/Superoxide Assay
Kelm, M., Dahmann, R., Wink, D. A., & Feelisch, M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.15.9922 · Cited by 165
Colorimetric assays for nitric oxide and nitrogen oxide species formed from nitric oxide stock solutions and donor compounds
Nims, R. W., Cook, J. C., Krishna, M. C., Christodoulou, D., Poore, C. M. B., Miles, A. M., Grisham, M. B., & Wink, D. A. (1996) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(96)68012-4 · Cited by 162
Nitric oxide chemistry and cellular signaling
Gow, A. J., & Ischiropoulos, H. (2001) · Journal of Cellular Physiology · doi:10.1002/jcp.1085 · Cited by 163
Flavohemoglobin denitrosylase catalyzes the reaction of a nitroxyl equivalent with molecular oxygen
Hausladen, A., Gow, A. J., & Stamler, J. S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.181199698 · Cited by 163
Mechanisms of nitrite bioactivation
Kim-Shapiro, D. B., & Gladwin, M. T. (2014) · Nitric Oxide · doi:10.1016/j.niox.2013.11.002 · Cited by 157
Steady-state and Transient Kinetics of Escherichia coli Nitric-oxide Dioxygenase (Flavohemoglobin)
Gardner, A. M., Martin, L. A., & Gardner, P. R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.17.12581 · Cited by 158
Nitric-oxide Dioxygenase Activity and Function of Flavohemoglobins
Gardner, P. R., Gardner, A. M., Martin, L. A., Dou, Y., Li, T., Olson, J. S., Zhu, H., & Riggs, A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004141200 · Cited by 159
Inhaled Nitric Oxide
Steudel, W., Hurford, W. E., Zapol, W. M., & Fisher, D. M. (1999) · Anesthesiology · doi:10.1097/00000542-199910000-00030 · Cited by 157
Nitrite and nitrate chemical biology and signalling
DeMartino, A. W., Kim‐Shapiro, D. B., Patel, R. P., & Gladwin, M. T. (2018) · British Journal of Pharmacology · doi:10.1111/bph.14484 · Cited by 162
Circulating no pool: assessment of nitrite and nitroso species in blood and tissues
Rassaf, T., Feelisch, M., & Kelm, M. (2003) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2003.11.011 · Cited by 158
Binding of Nitric Oxide and Carbon Monoxide to Soluble Guanylate Cyclase As Observed with Resonance Raman Spectroscopy
Deinum, G., Stone, J. R., Babcock, Ǵ., & Marletta, M. A. (1996) · Biochemistry · doi:10.1021/bi952440m · Cited by 153
The Pathobiochemistry of Nitrogen Dioxide
Kirsch, M., Korth, H.-G., Sustmann, R., & Groot, H. D. (2002) · Biological Chemistry · doi:10.1515/bc.2002.043 · Cited by 150
ICCC34 — golden edition of coordination chemistry reviews. Coordination chemistry for the neurosciences
Burdette, S. C., & Lippard, S. J. (2001) · Coordination Chemistry Reviews · doi:10.1016/s0010-8545(01)00308-3 · Cited by 148
Nitric oxide localized to spinal cords of mice with experimental allergic encephalomyelitis: an electron paramagnetic resonance study.
Lin, R. F., Lin, T., Tilton, R. G., & Cross, A. H. (1993) · The Journal of Experimental Medicine · doi:10.1084/jem.178.2.643 · Cited by 148
Hemoglobin-mediated nitric oxide signaling
Helms, C., & Kim-Shapiro, D. B. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.04.028 · Cited by 146
Nitric oxide is a ubiquitous signal for maintaining redox balance in plant cells: regulation of ascorbate peroxidase as a case study
Correa‐Aragunde, N., Foresi, N. P., & Lamattina, L. (2015) · Journal of Experimental Botany · doi:10.1093/jxb/erv073 · Cited by 145
Nitric Oxide Inactivates NADPH Oxidase in Pig Neutrophils by Inhibiting Its Assembling Process
Fujii, H., Ichimori, K., Hoshiai, K., & Nakazawa, H. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.52.32773 · Cited by 142
Reactions of NO and nitrite with heme models and proteins
Ford, P. C. (2010) · Inorganic Chemistry · doi:10.1021/ic902073z · Cited by 138
Biochemical Characterization of HumanS-Nitrosohemoglobin
Patel, R. P., Hogg, N., Spencer, N. Y., Kalyanaraman, B., Matalon, S., & Darley-Usmar, V. M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.22.15487 · Cited by 133
Acute l-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance
Bailey, S. J., Winyard, P. G., Vanhatalo, A., Blackwell, J. R., DiMenna, F. J., Wilkerson, D. P., & Jones, A. M. (2010) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00503.2010 · Cited by 132
Detection of nitric oxide by electron paramagnetic resonance spectroscopy
Hogg, N. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.03.009 · Cited by 135
Synthesis of sol-gel encapsulated heme proteins with chemical sensing properties
Lan, E. H., Dave, B. C., Fukuto, J. M., Dunn, B., Zink, J. I., & Valentine, J. S. (1999) · Journal of Materials Chemistry · doi:10.1039/a805541f · Cited by 130
Treatment of persistent pulmonary hypertension in the newborn lamb by inhaled nitric oxide
Zayek, M., Cleveland, D. J., & Morin, F. C. (1993) · The Journal of Pediatrics · doi:10.1016/s0022-3476(06)80020-x · Cited by 130
Storage lesion in banked blood due to hemolysis-dependent disruption of nitric oxide homeostasis
Gladwin, M. T., & Kim‐Shapiro, D. B. (2009) · Current Opinion in Hematology · doi:10.1097/moh.0b013e32833157f4 · Cited by 130
Can We Model Nitric Oxide Biotransport? A Survey of Mathematical Models for a Simple Diatomic Molecule with Surprisingly Complex Biological Activities
Buerk, D. G. (2001) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.3.1.109 · Cited by 128
High Sensitivity, Humidity-Independent, Flexible NO 2 and NH 3 Gas Sensors Based on SnS 2 Hybrid Functional Graphene Ink
Huang, Y., Jiao, W., Chu, Z., Wang, S., Chen, L., Nie, X., Wang, R., & He, X. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b14952 · Cited by 122
Hemoglobins dioxygenate nitric oxide with high fidelity
Gardner, P. R., Gardner, A. M., Brashear, W. T., Suzuki, T., Hvitved, A. N., Setchell, K. D. R., & Olson, J. S. (2006) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2005.12.012 · Cited by 123
Pathogenesis and Treatment of the Adult Respiratory Distress Syndrome
Fulkerson, W. J. (1996) · Archives of Internal Medicine · doi:10.1001/archinte.1996.00440010035006 · Cited by 122
Nitrite Reduction and Cardiovascular Protection
Omar, S. A., & Webb, A. J. (2014) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2014.01.012 · Cited by 121
Protection from nitrosative stress: A central role for microbial flavohemoglobin
Forrester, M. T., & Foster, M. W. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.01.028 · Cited by 127
Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins
Miranda, K. M., Nims, R. W., Thomas, D. D., Espey, M. G., Citrin, D. E., Bartberger, M. D., Paolocci, N., Fukuto, J. M., Feelisch, M., & Wink, D. A. (2003) · Journal of Inorganic Biochemistry · doi:10.1016/s0162-0134(02)00498-1 · Cited by 121
Spectral Characterization and Effect on Catalytic Activity of Nitric Oxide Complexes of Inducible Nitric Oxide Synthase
Hurshman, A. R., & Marletta, M. A. (1995) · Biochemistry · doi:10.1021/bi00016a038 · Cited by 120
Myoglobin as a model system for designing heme protein based blood substitutes
Dou, Y., Maillett, D. H., Eich, R. F., & Olson, J. S. (2002) · Biophysical Chemistry · doi:10.1016/s0301-4622(02)00090-x · Cited by 118
Differences in Three Kinetic Parameters Underpin the Unique Catalytic Profiles of Nitric-oxide Synthases I, II, and III
Santolini, J., Meade, A. L., & Stuehr, D. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m108666200 · Cited by 116
The Biological Chemistry of Peroxynitrite
Radí, R., Denicola, A., Álvarez, B., Ferrer‐Sueta, G., & Rubbo, H. (2000) · Elsevier eBooks · doi:10.1016/b978-012370420-7/50005-8 · Cited by 115
The Modulation of Oxygen Radical Production by Nitric Oxide in Mitochondria
Sarkela, T. M., Berthiaume, J. M., Elfering, S. L., Gybina, A. A., & Giulivi, C. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m007625200 · Cited by 114
Safety and Feasibility of Long-term Intravenous Sodium Nitrite Infusion in Healthy Volunteers
Pluta, R. M., Oldfield, E. H., Bakhtian, K. D., Fathi, A. R., Smith, R. K., DeVroom, H. L., Nahavandi, M., Woo, S., Figg, W. D., & Lonser, R. R. (2011) · PLoS ONE · doi:10.1371/journal.pone.0014504 · Cited by 112
Ultrasensitive room temperature ppb-level NO 2 gas sensors based on SnS 2 /rGO nanohybrids with P–N transition and optoelectronic visible light enhancement performance
Huang, Y., Jiao, W., Chu, Z., Ding, G., Yan, M., Zhong, X., & Wang, R. (2019) · Journal of Materials Chemistry C · doi:10.1039/c9tc02436k · Cited by 112
Mechanisms of Cell Signaling by Nitric Oxide and Peroxynitrite: From Mitochondria to MAP Kinases
Levonen, A., Patel, R. P., Brookes, P. S., Go, Y., Jo, H., Parthasarathy, S., Anderson, P. G., & Darley-Usmar, V. M. (2001) · Antioxidants and Redox Signaling · doi:10.1089/152308601300185188 · Cited by 113
Kinetic and spectroscopic characterization of an intermediate peroxynitrite complex in the nitrogen monoxide induced oxidation of oxyhemoglobin
Herold, S. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)01345-3 · Cited by 112
Nitrite Reduction Mediated by Heme Models. Routes to NO and HNO?
Heinecke, J. L., Khin, C., Pereira, J. C. M., Suárez, S., Iretskii, A. V., Doctorovich, F. A., & Ford, P. C. (2013) · Journal of the American Chemical Society · doi:10.1021/ja312092x · Cited by 108
Mechanism of Aerobic Decomposition of Angeli's Salt (Sodium Trioxodinitrate) at Physiological pH
Miranda, K. M., Dutton, A. S., Ridnour, L. A., Foreman, C. A., Ford, E., Paolocci, N., Katori, T., Tocchetti, C. G., Mancardi, D., Thomas, D. D., et al. (2004) · Journal of the American Chemical Society · doi:10.1021/ja045480z · Cited by 109
Helicobacter pyloriGenerates Superoxide Radicals and Modulates Nitric Oxide Metabolism
Nagata, K., Yu, H., Nishikawa, M., Kashiba, M., Nakamura, A., Sato, E. F., Tamura, T., & Inoue, M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.23.14071 · Cited by 106
Merkel cell carcinoma: combined surgery and radiation therapy.
Cotlar, A. M., Gates, J., & Gibbs, F. A. (1986) · PubMed · Cited by 106
Assessing the influence of component processing and donor characteristics on quality of red cell concentrates using quality control data
Jordan, A., Chen, D., Yi, Q. ‐., Kanias, T., Gladwin, M. T., & Acker, J. P. (2016) · Vox Sanguinis · doi:10.1111/vox.12378 · Cited by 105
Inactivation of macrophage nitric oxide synthase activity by NG-Methyl-L-arginine
Olken, N. M., Rusche, K. M., Richards, M. K., & Marletta, M. A. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)91864-9 · Cited by 105
Nitric Oxide Signaling and Regulation in the Cardiovascular System: Recent Advances
Carlström, M., Weitzberg, E., & Lundberg, J. O. (2024) · Pharmacological Reviews · doi:10.1124/pharmrev.124.001060 · Cited by 103
Physiological reactions of nitric oxide and hemoglobin: A radical rethink
Gross, S. S., & Lane, P. B. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.18.9967 · Cited by 103
Red Blood Cell Nitric Oxide as an Endocrine Vasoregulator
Datta, B. N., Tufnell-Barret, T., Bleasdale, R. A., Jones, C. J. H., Beeton, I., Paul, V., Frenneaux, M. P., & James, P. E. (2004) · Circulation · doi:10.1161/01.cir.0000124450.07016.1d · Cited by 102
The Chemical Biology of Nitric Oxide
Wink, D. A., Feelisch, M., Yoram Vodovotz, B., Fukuto, J. M., & Grisham, M. B. (2006) · Kluwer Academic Publishers eBooks · doi:10.1007/0-306-46806-9_10 · Cited by 102
Origin and Impact of Nitric Oxide in Pseudomonas aeruginosa Biofilms
Cutruzzolà, F., & Frankenberg‐Dinkel, N. (2015) · Journal of Bacteriology · doi:10.1128/jb.00371-15 · Cited by 105
Recent methodological advances in the analysis of nitrite in the human circulation: Nitrite as a biochemical parameter of the l-arginine/NO pathway
Grau, M., Hendgen-Cotta, U. B., Brouzos, P., Drexhage, C., Rassaf, T., Lauer, T., Dejam, A., Kelm, M., & Kleinbongard, P. (2007) · Journal of Chromatography B · doi:10.1016/j.jchromb.2007.02.002 · Cited by 100
Nitric oxide reaction with red blood cells and hemoglobin under heterogeneous conditions
Han, T. H., Hyduke, D. R., Vaughn, M. W., Fukuto, J. M., & Liao, J. C. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.122118299 · Cited by 100
The Specificity of Nitroxyl Chemistry Is Unique Among Nitrogen Oxides in Biological Systems
Flores‐Santana, W., Salmon, D. J., Donzelli, S., Switzer, C., Basudhar, D., Ridnour, L. A., Cheng, R. Y. S., Glynn, S. A., Paolocci, N., Fukuto, J. M., et al. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3841 · Cited by 102
Haptoglobin: Old protein with new functions
Alayash, A. I. (2010) · Clinica Chimica Acta · doi:10.1016/j.cca.2010.12.011 · Cited by 99
Reactions of Deoxy-, Oxy-, and Methemoglobin with Nitrogen Monoxide
Herold, S., & Röck, G. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210275200 · Cited by 99
Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm
Wink, D. A., Miranda, K. M., Katori, T., Mancardi, D., Thomas, D. D., Ridnour, L. A., Espey, M. G., Feelisch, M., Colton, C. A., Fukuto, J. M., et al. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00531.2003 · Cited by 99
Mechanisms of Peroxynitrite Interactions with Heme Proteins
Su, J., & Groves, J. T. (2010) · Inorganic Chemistry · doi:10.1021/ic902157z · Cited by 99
S -Nitrosothiols and the S -Nitrosoproteome of the Cardiovascular System
Maron, B. A., Tang, S., & Loscalzo, J. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.4744 · Cited by 101
Nifedipine Increases Endothelial Nitric Oxide Bioavailability by Antioxidative Mechanisms
Berkels, R., Egink, G., Marsen, T. A., Bartels, H., Roesen, R., & Klaus, W. (2001) · Hypertension · doi:10.1161/01.hyp.37.2.240 · Cited by 97
The Catabolic Fate of Nitric Oxide
Pearce, L. L., Kanai, A., Birder, L. A., Pitt, B. R., & Peterson, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109838200 · Cited by 96
Nitric oxide scavenging by red cell microparticles
Liu, C., Zhao, W., Christ, G. J., Gladwin, M. T., & Kim‐Shapiro, D. B. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.09.002 · Cited by 98
Regeneration of the Ferrous Heme of Soluble Guanylate Cyclase from the Nitric Oxide Complex: Acceleration by Thiols and Oxyhemoglobin
Brandish, P. E., Buechler, W. A., & Marletta, M. A. (1998) · Biochemistry · doi:10.1021/bi9814989 · Cited by 95
ESR spectral transition by arteriovenous cycle in nitric oxide hemoglobin of cytokine-treated rats
Kosaka, H., Sawai, Y., Sakaguchi, H., Kumura, E., Harada, N., Watanabe, M., & Shiga, T. (1994) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1994.266.5.c1400 · Cited by 95
Myoglobin Catalyzes Its Own Nitration
Bourassa, J. L., Ives, E. P., Marqueling, A. L., Shimanovich, R., & Groves, J. T. (2001) · Journal of the American Chemical Society · doi:10.1021/ja015621m · Cited by 95
Effect of inhibitors of nitric oxide release and action on vascular tone in isolated lungs of pig, sheep, dog and man.
Cremona, G., Wood, A. M., Hall, L. W., Bower, E. A., & Higenbottam, T. (1994) · The Journal of Physiology · doi:10.1113/jphysiol.1994.sp020429 · Cited by 94
The modulation of ferryl myoglobin formation and its oxidative effects on low density lipoproteins by nitric oxide
Dee, G., Rice-Evans, C. A., Obeyesekera, S., Meraji, S., Jacobs, M., & Bruckdorfer, K. R. (1991) · FEBS Letters · doi:10.1016/0014-5793(91)81338-9 · Cited by 93
Cytochrome b5 Reductase 3 Modulates Soluble Guanylate Cyclase Redox State and cGMP Signaling
Rahaman, M. M., Nguyen, A. T., Miller, M. P., Hahn, S. A., Sparacino-Watkins, C., Jobbagy, S., Carew, N. T., Cantu-Medellin, N., Wood, K. C., Baty, C. J., et al. (2017) · Circulation Research · doi:10.1161/circresaha.117.310705 · Cited by 92
The redox interplay between nitrite and nitric oxide: From the gut to the brain
Pereira, C., Ferreira, N. R., Rocha, B. S., Barbosa, R. M., & Laranjinha, J. (2013) · Redox Biology · doi:10.1016/j.redox.2013.04.004 · Cited by 92
Biological signaling by small inorganic molecules
Basudhar, D., Ridnour, L. A., Cheng, R. Y. S., Kesarwala, A. H., Heinecke, J. L., & Wink, D. A. (2015) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2015.06.001 · Cited by 93
Continuous monitoring of cellular nitric oxide generation by spin trapping with an iron-dithiocarbamate complex
Kotake, Y., Tanigawa, T., Tanigawa, M., Ueno, I., Allen, D. R., & Lai, C. (1996) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(95)00172-7 · Cited by 91
Nitric oxide binding to oxygenated hemoglobin under physiological conditions
Huang, Z., Louderback, J. G., Goyal, M., Azizi, F., King, S. B., & Kim‐Shapiro, D. B. (2001) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(01)00227-6 · Cited by 91
Immunohistochemical localization of endothelial nitric oxide synthase in human villous and extravillous trophoblast populations and expression during syncytiotrophoblast formation in vitro
Eis, A., Brockman, D. E., Pollock, J. S., & Myatt, L. (1995) · Placenta · doi:10.1016/0143-4004(95)90000-4 · Cited by 91
Nitric Oxide Releasing d -α-Tocopheryl Polyethylene Glycol Succinate for Enhancing Antitumor Activity of Doxorubicin
Song, Q., Tan, S., Zhuang, X., Guo, Y., Zhao, Y., Wu, T., Qi, Y., Si, L., & Zhang, Z. (2014) · Molecular Pharmaceutics · doi:10.1021/mp5003009 · Cited by 90
Nitrite enhances RBC hypoxic ATP synthesis and the release of ATP into the vasculature: a new mechanism for nitrite-induced vasodilation
Cao, Z., Bell, J. B., Mohanty, J. G., Nagababu, E., & Rifkind, J. M. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01233.2008 · Cited by 90
Depletion of Endogenous Nitric Oxide Enhances Cisplatin-induced Apoptosis in a p53-dependent Manner in Melanoma Cell Lines
Tang, C., & Grimm, E. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m310821200 · Cited by 90
Dioxygen-dependent metabolism of nitric oxide in mammalian cells
Gardner, P. R., Martin, L. A., Hall, D., & Gardner, A. M. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00569-x · Cited by 91
Nitric oxide reactivity and mechanisms involved in its biological effects
Mateo, A. O., & de Artiñano, M. A. A. (2000) · Pharmacological Research · doi:10.1006/phrs.2000.0701 · Cited by 90
Rate of nitric oxide scavenging by hemoglobin bound to haptoglobin
Azarov, I., He, X., Jeffers, A. B., Basu, S., Ucer, B., Hantgan, R. R., Levy, A. P., & Kim‐Shapiro, D. B. (2008) · Nitric Oxide · doi:10.1016/j.niox.2008.02.006 · Cited by 89
Regulation of Cellular Gas Exchange, Oxygen Sensing, and Metabolic Control
Clanton, T. L., Hogan, M. C., & Gladden, L. B. (2013) · Comprehensive physiology · doi:10.1002/cphy.c120030 · Cited by 91
Iron dithiocarbamate as spin trap for nitric oxide detection: Pitfalls and successes
Vanin, A. F., Huisman, A., & van Faassen, E. E. (2002) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(02)59169-2 · Cited by 87
Chemistry of Nitric Oxide: Biologically Relevant Aspects
Fukuto, J. M. (1995) · Advances in pharmacology · doi:10.1016/s1054-3589(08)61078-9 · Cited by 87
Involvement of the Reductase Domain of Neuronal Nitric Oxide Synthase in Superoxide Anion Production
Miller, R. T., Martásek, P., Roman, L. J., Nishimura, J. S., & Masters, B. S. S. (1997) · Biochemistry · doi:10.1021/bi972022c · Cited by 86
Nitrite reduction by molybdoenzymes: a new class of nitric oxide-forming nitrite reductases
Maia, L. B., & Moura, J. J. G. (2015) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-014-1234-2 · Cited by 88
Endothelium-dependent hyperpolarization of smooth muscle cells in rabbit femoral arteries is not mediated by EDRF (nitric oxide)
Huang, A., Busse, R., & Bassenge, E. (1988) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/bf00172124 · Cited by 86
Interference of Carboxy-PTIO with Nitric Oxide- and Peroxynitrite-Mediated Reactions
Pfeiffer, S., Leopold, E., Hemmens, B., Schmidt, K., Werner, E. R., & Mayer, B. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00407-8 · Cited by 85
The molecular mechanism of mammalian NO-synthases: A story of electrons and protons
Santolini, J. (2010) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2010.10.011 · Cited by 87
Mechanistic studies of nitrite reactions with metalloproteins and models relevant to mammalian physiology
Heinecke, J. L., & Ford, P. C. (2009) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2009.07.021 · Cited by 82
NO and NO interactions with group 8 metalloporphyrins
Lim, M. D., Lorković, I. M., & Ford, P. C. (2004) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2004.10.002 · Cited by 81
Aminotroponiminates as Ligands for Potential Metal-Based Nitric Oxide Sensors
Franz, K. J., Singh, N., Spingler, B., & Lippard, S. J. (2000) · Inorganic Chemistry · doi:10.1021/ic000344q · Cited by 81
Hypoxia Tolerance, Nitric Oxide, and Nitrite: Lessons From Extreme Animals
Fago, A., & Jensen, F. B. (2015) · Physiology · doi:10.1152/physiol.00051.2014 · Cited by 82
Autocatalytic oxidation of hemoglobin induced by nitrite: Activation and chemical inhibition
Doyle, M. P., Herman, J. G., & Dykstra, R. L. (1985) · Journal of Free Radicals in Biology & Medicine · doi:10.1016/0748-5514(85)90019-4 · Cited by 81
Self-citation
A chemist's view of the nitric oxide story
Williams, D. L. H. (2003) · Organic & Biomolecular Chemistry · doi:10.1039/b209748f · Cited by 80

Authors: Doyle, M. P., & Hoekstra, J. W.
Affiliations: Hope College (US)
Corresponding author: Doyle, Michael P.
ORCID: Doyle, Michael P.
Venue: Journal of Inorganic Biochemistry
Publisher: Elsevier BV
Published: 1981-01
Volume: 14
Issue: 4
Pages: 351-358
ISSN: 0162-0134 (ISSN-L)
DOI: 10.1016/s0162-0134(00)80291-3
OpenAlex: W2019435702
Cited by: 643
References: 24
Citations by year: 2026: 1 · 2025: 11 · 2024: 12 · 2023: 13 · 2022: 11 · 2021: 13 · 2020: 14 · 2019: 14 · 2018: 19 · 2017: 12 · 2016: 7 · 2015: 17 · 2014: 13 · 2013: 26 · 2012: 15
FWCI: 1.05
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Inorganic Biochemistry (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Hemoglobin structure and function
Physical Sciences › Chemistry › Inorganic Chemistry › Metal-Catalyzed Oxygenation Mechanisms
Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
Keywords: NO oxidation, heme proteins, myoglobin, hemoglobin, dinitrogen trioxide, dinitrogen tetroxide, nitrate formation, reaction mechanism, rate constants
MeSH terms: Animals, Hemoglobin A, Horses, Humans, Kinetics, Myocardium, Myoglobin, Nitric Oxide, Nitrogen Oxides, Oxidation-Reduction, Oxyhemoglobins

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Oxidation of nitrogen-oxides by bound dioxygen in hemoproteins

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks