Brain trace elements and aging
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Total iron concentrations increase with age in the substantia nigra, putamen, globus pallidus, caudate nucleus, and cortices.
“Total iron concentrations increase with age in the substantia nigra, putamen, globus pallidus, caudate nucleus, and cortices6,42–44 but why this increase is selective for some areas of the brain is unclear.”
From The role of iron in brain ageing and neurodegenerative disorders (2014) · cites this paper as [44]
Cites
Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains
Riederer, P., Sofic, E., Rausch, W., Schmidt, B., Reynolds, G. P., Jellinger, K., & Youdim, M. B. H. (1989) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1989.tb09150.x · Cited by 1,383 · see citing works
DEXTER, D. T., CARAYON, A., JAVOY-AGID, F., AGID, Y., WELLS, F. R., DANIEL, S. E., LEES, A. J., JENNER, P., & MARSDEN, C. D. (1991) · Brain · doi:10.1093/brain/114.4.1953 · Cited by 1,043 · see citing works
Altered Brain Metabolism of Iron as a Cause of Neurodegenerative Diseases?
Gerlach, M., Ben‐Shachar, D., Riederer, P. F., & Youdim, M. B. H. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.63030793.x · Cited by 704 · see citing works
Dendritic Growth in the Aged Human Brain and Failure of Growth in Senile Dementia
Buell, S. J., & Coleman, P. D. (1979) · Science · doi:10.1126/science.493989 · Cited by 475 · see citing works
Trace element analytical chemistry in medicine and biology
Brätter, P., & Schramel, P. (1980) · De Gruyter eBooks · Cited by 385 · see citing works
Complex I, iron, and ferritin in Parkinson's disease substantia nigra
Mann, V. M., Cooper, J. M., Daniel, S. E., Srai, K., Jenner, P., Marsden, C. D., & Schapira, A. H. V. (1994) · Annals of Neurology · doi:10.1002/ana.410360612 · Cited by 251 · see citing works
Brain trace element concentrations in aging
Markesbery, W. R., Ehmann, W. D., Alauddin, M., & Hossain, T. I. M. (1984) · Neurobiology of Aging · doi:10.1016/0197-4580(84)90081-2 · Cited by 225 · see citing works
Iron regulation in the brain: Histochemical, biochemical, and molecular considerations
Connor, J. R., & Benkovic, S. A. (1992) · Annals of Neurology · doi:10.1002/ana.410320710 · Cited by 178 · see citing works
Iron and Other Metals in Neuromelanin, Substantia Nigra, and Putamen of Human Brain
Zecca, L., Pietra, R., Goj, C., Mecacci, C., Radice, D., & Sabbioni, E. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62031097.x · Cited by 163 · see citing works
Internucleosomal DNA Cleavage Involved in Ischemia-Induced Neuronal Death
Okamoto, M., Matsumoto, M., Ohtsuki, T., et al. (1993) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1993.2402 · Cited by 137 · see citing works
Accurate calibration of a Si(Li) detector for PIXE analysis
Maenhaut, W., & Raemdonck, H. (1984) · Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms · doi:10.1016/0168-583x(84)90484-1 · Cited by 136 · see citing works
Self-citationCurrent Topics in Nutrition and Disease
Armstrong, J. (1981) · Europe PMC (PubMed Central) · Cited by 126 · see citing works
Apoptosis—programmed cell death: a role in the aging process?
Monti, D., Troiano, L., Tropea, F., et al. (1992) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/55.6.1208s · Cited by 96 · see citing works
Maenhaut, W., Reu, L. D., Rinsvelt, H. A. V., et al. (1980) · Nuclear Instruments and Methods · doi:10.1016/0029-554x(80)91310-5 · Cited by 82 · see citing works
Self-citationGelman, B. B. (1995) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199507000-00001 · Cited by 62 · see citing works
Accurate Analytic Fitting of Pixe Spectra
Maenhaut, W., & Vandenhaute, J. (1986) · Bulletin des Sociétés Chimiques Belges · doi:10.1002/bscb.19860950514 · Cited by 57 · see citing works
Self-citationCiriolo, M. R., Fışkın, K., Demartino, A., et al. (1991) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(91)90061-4 · Cited by 51 · see citing works
Regional distribution of potassium, calcium, and six trace elements in normal human brain
Duflou, H., Maenhaut, W., & Reuck, J. D. (1989) · Neurochemical Research · doi:10.1007/bf00965616 · Cited by 50 · see citing works
Self-citationWille, R. L., & Albert, M. L. (1985) · AJN American Journal of Nursing · doi:10.2307/3424987 · Cited by 49 · see citing works
Branconnier, R. J., Branconnier, M. E., Walshe, T. M., McCarthy, C., & Morse, P. A. (1992) · PubMed · Cited by 19 · see citing works
Maenhaut, W., Hebbrecht, G., & Reuck, J. D. (1993) · Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms · doi:10.1016/0168-583x(93)95639-m · Cited by 10 · see citing works
Self-citationTempel, K. H., & Ignatius, A. A. (1993) · Archives of Toxicology · doi:10.1007/bf01973702 · Cited by 8 · see citing works
Origin of Senescence: A Review
Suzuki, K. (2008) · Hormone Research · doi:10.1159/000182749 · Cited by 7 · see citing works
Cohadon, F., & Desbordes, P. (2009) · Gerontology · doi:10.1159/000212827 · Cited by 6 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The role of iron in brain ageing and neurodegenerative disorders
Ward, R. J., Zucca, F. A., Duyn, J. H., Crichton, R. R., & Zecca, L. (2014) · The Lancet Neurology · doi:10.1016/s1474-4422(14)70117-6 · Cited by 1,819 · see citing works
Imaging iron stores in the brain using magnetic resonance imaging
Haacke, E. M., Cheng, N. Y. C., House, M. J., Liu, Q., Neelavalli, J., Ogg, R. J., Khan, A., Ayaz, M., Kirsch, W., & Obenaus, A. (2005) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2004.10.001 · Cited by 995 · see citing works
Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease
Zucca, F. A., Segura-Aguilar, J., Ferrari, E., Muñoz, P., Paris, I., Sulzer, D., Sarna, T., Casella, L., & Zecca, L. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.09.012 · Cited by 659 · see citing works
Overview of quantitative susceptibility mapping
Deistung, A., Schweser, F., & Reichenbach, J. R. (2017) · NMR in Biomedicine · doi:10.1002/nbm.3569 · Cited by 338 · see citing works
Ramos, P., Santos, A., Pinto, N. R., Mendes, R., Magalhães, T., & Almeida, A. (2014) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2013.08.001 · Cited by 221 · see citing works
- Authors
- Hebbrecht, G., Maenhaut, W., & Reuck, J. D.
- Affiliations
- Ghent University (BE)
- Ghent University Hospital (BE)
- Corresponding author
- Maenhaut, Willy
- Venue
- Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms
- Publisher
- Elsevier BV
- Published
- 1999-04
- Volume
- 150
- Issue
- 1-4
- Pages
- 208-213
- ISSN
- 0168-583X (ISSN-L)
- OpenAlex
- W2024578063
- Cited by
- 53
- References
- 24
- Citations by year
- 2025: 1 · 2024: 5 · 2023: 1 · 2021: 5 · 2020: 3 · 2019: 4 · 2018: 1 · 2017: 2 · 2016: 5 · 2015: 1 · 2014: 5 · 2013: 4 · 2012: 2
- FWCI
- 0.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms (publishedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Funders
- Vlaamse regering
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
- Life Sciences › Neuroscience › Neurology › Neurological diseases and metabolism
- Keywords
- brain aging, trace elements, elemental concentrations, potassium, calcium, iron, zinc, selenium, rubidium, manganese, copper, cerebral cortex, white matter, basal ganglia, brainstem, cerebellar cortex, postmortem brain, oxygen free radicals, neurodegeneration, immunological defense
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review