PHF and PHF-like fibrils –cause or consequence?
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Neuronal degeneration in AD could occur via non-NFT formation in multiple neurons.
“Interestingly, it has been reported that neuronal degeneration in AD could occur via non-NFT formation in multiple neurons [44].”
From Enhanced microglial dynamics and a paucity of tau seeding in the amyloid plaque microenvironment contribute to cognitive resilience in Alzheimer’s disease (2024) · cites this paper as [44]
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“Interestingly, it has been reported that neuronal degeneration in AD could occur via non-NFT formation in multiple neurons [44].”
BackgroundEndogenous Tau Aggregates in Oligodendrocytes of rTg4510 Mice Induced by Human P301L Tau
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Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease
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Tanninen, S. E. (2018) · TSpace (University of Toronto)
- Authors
- Ihara, Y.
- Affiliations
- The University of Tokyo (JP)
- Corresponding author
- Ihara, Y
- ORCID
- Ihara, Y
- Venue
- Neurobiology of Aging
- Publisher
- Elsevier BV
- Published
- 2001-01
- Volume
- 22
- Issue
- 1
- Pages
- 123-126
- ISSN
- 0197-4580 (ISSN-L)
- OpenAlex
- W2043618425
- Cited by
- 28
- References
- 27
- Citations by year
- 2024: 1 · 2023: 1 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 2 · 2014: 3 · 2013: 1
- FWCI
- 1.38
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurobiology of Aging (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiopharmaceutical Chemistry and Applications
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- tau oligomers, Alzheimer's disease, isoproterenol, radioligand synthesis, reductive alkylation, norepinephrine, positron emission tomography, brain penetration, PET radiotracer
- MeSH terms
- Alzheimer Disease, Animals, Antibodies, Monoclonal, Exons, Humans, Microtubule-Associated Proteins, Mutation, Neurofibrillary Tangles, tau Proteins
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