Cited by 502Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsDementia and Cognitive Impairment Research

Neuron loss in APP transgenic mice

Calhoun, Michael E., Wiederhold, Karl-Heinz, Abramowski, Dorothee, Phinney, Amie L., Probst, Alphonse, Sturchler-Pierrat, Christine, Staufenbiel, Matthias, Sommer, Bernd +1 more·1998·Nature

Integrity signals

Registry

Crossref · 10.1038/27351

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • In the APP23 model, a reduction in CA1 neuron number of 14% has been demonstrated, but inclusion of both hemi- and homozygous mice aged 14 to 18 months complicates interpretation.

    “A reduction in the CA1 neuron number of 14% has been demonstrated; however, in this study, both hemi- and homozygous mice with an age of 14 to 18 months were included, which complicates interpretation of the data [41].”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Calhoun, M. E., Wiederhold, K.-H., Abramowski, D., Phinney, A. L., Probst, A., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., & Jucker, M.
Affiliations
  • University of Basel (CH)
  • Novartis (Switzerland) (CH)
Venue
Nature
Published
1998-10
Volume
395
Issue
6704
Pages
755-756
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
OpenAlex
W1572812739
Cited by
502
References
2
Citations by year
2026: 1 · 2025: 9 · 2024: 9 · 2023: 8 · 2022: 11 · 2021: 10 · 2020: 9 · 2019: 11 · 2018: 10 · 2017: 16 · 2016: 8 · 2015: 20 · 2014: 15 · 2013: 19 · 2012: 21
FWCI
17.41
Type
journal article
Language
en
Open access
closed
Locations
  • Nature (publishedVersion)
  • PubMed (publishedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords
Alzheimer's disease, amyloid plaques, amyloid precursor protein, APP transgenic mice, neuronal cell death, neurodegeneration, familial Alzheimer's disease
MeSH terms
Alzheimer Disease, Animals, Humans, Mice, Transgenic, Mutation, Neurons, Amyloid beta-Protein Precursor, Cell Death, Mice, Plaque, Amyloid

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review