Depression, endocrinologically a syndrome of premature aging?
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MDD has been considered a syndrome of 'premature aging'.
“Major depressive disorder (MDD) has been considered a syndrome of “premature aging” (Heuser, 2002), and this notion has been reiterated in several recent reviews (Kinser and Lyon, 2013; Luca et al., 2013; Wolkowitz et al., 2011b).”
From Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging (2015) · cites this paper as Heuser, 2002
Cites
Lamberts, S. W. J., van den Beld, A. W., & van der Lely, A.-J. (1997) · Science · doi:10.1126/science.278.5337.419 · Cited by 980 · see citing works
Holsboer, F. (1999) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(98)90056-5 · Cited by 654 · see citing works
(1996) · PubMed · Cited by 643 · see citing works
Depression Is a Risk Factor for Coronary Artery Disease in Men
Ford, D. E., Mead, L. A., Chang, P. P., Cooper, L. A., Wang, N., & Klag, M. J. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.13.1422 · Cited by 586 · see citing works
Stress, hypercortisolism and corticosteroid receptors in depression: implicatons for therapy
Holsboer, F. (2001) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00352-9 · Cited by 575 · see citing works
Heuser, I. J. E., Gotthardt, U., Schweiger, U., Schmider, J., Lammers, C.-H., Dettling, M., & Holsboer, F. (1994) · Neurobiology of Aging · doi:10.1016/0197-4580(94)90117-1 · Cited by 240 · see citing works
Self-citationTestosterone, Gonadotropin, and Cortisol Secretion in Male Patients With Major Depression
Schweiger, U., Deuschle, M., Weber, B., Körner, A., Lammers, C., Schmider, J., Gotthardt, U., & Heuser, I. (1999) · Psychosomatic Medicine · doi:10.1097/00006842-199905000-00007 · Cited by 222 · see citing works
Self-citationHypercortisolemic Depression Is Associated With Increased Intra-Abdominal Fat
Weber-Hamann, B., Hentschel, F., Kniest, A., Deuschle, M., Colla, M., Lederbogen, F., & Heuser, I. (2002) · Psychosomatic Medicine · doi:10.1097/00006842-200203000-00010 · Cited by 219 · see citing works
Self-citationLow lumbar bone mineral density in patients with major depression
(1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.11.1691 · Cited by 165 · see citing works
Schweiger, U., Weber, B., Deuschle, M., & Heuser, I. (2000) · American Journal of Psychiatry · doi:10.1176/ajp.157.1.118 · Cited by 101 · see citing works
Self-citationDeuschle, M., Weber, B., Colla, M., Depner, M., & Heuser, I. (1998) · Stress · doi:10.3109/10253899809167292 · Cited by 87 · see citing works
Self-citationSteiger, A., von Bardeleben, U., Wiedemann, K., & Holsboer, F. (1991) · Journal of Psychiatric Research · doi:10.1016/0022-3956(91)90021-2 · Cited by 61 · see citing works
Heuser, I., Deuschle, M., Weber, A., Kniest, A., Ziegler, C., Weber, B., & Colla, M. (2000) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00145-7 · Cited by 47 · see citing works
Self-citationInsulin secretion and insulin sensitivity in major depression
Weber, B., Schweiger, U., Deuschle, M., Standhard, H., Körner, A., Schmider, J., Lammers, C.-H., Motzek, T., & Heuser, I. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(95)94449-7 · Cited by 3 · see citing works
Self-citationIncreased IGF-1 in patients with major depression
Deuschle, M., Blum, W. F., Schweiger, U., et al. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(95)94450-b · Cited by 2 · see citing works
Heuser, I., Bissette, G., Dettling, M., Schweiger, U., Gotthardt, U., Schmider, J., Lammers, C.-H., Nemeroff, C. B., & Holsboer, F. (1998) · Depression and Anxiety · doi:10.1002/(sici)1520-6394(1998)8:2
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Mood disorders and allostatic load
McEwen, B. S. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00177-x · Cited by 1,135 · see citing works
The stress system in the human brain in depression and neurodegeneration
Swaab, D. F., Bao, A.-M., & Lucassen, P. J. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.03.003 · Cited by 984 · see citing works
Wolkowitz, O. M., Mellon, S. H., Epel, E. S., Lin, J., Dhabhar, F. S., Su, Y., Reus, V. I., Rosser, R., Burke, H. M., Kupferman, E., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017837 · Cited by 421 · see citing works
Depression gets old fast: do stress and depression accelerate cell aging?
Wolkowitz, O. M., Epel, E. S., Reus, V. I., & Mellon, S. H. (2010) · Depression and Anxiety · doi:10.1002/da.20686 · Cited by 298 · see citing works
Lindqvist, D., Epel, E. S., Mellon, S. H., Penninx, B. W., Révész, D., Verhoeven, J. E., Reus, V. I., Lin, J., Mahan, L., Hough, C. M., et al. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.05.007 · Cited by 285 · see citing works
Advanced BrainAGE in older adults with type 2 diabetes mellitus
Franke, K., Gaser, C., Manor, B., & Novak, V. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2013.00090 · Cited by 221 · see citing works
Garcia-Rizo, C., Fernandez-Egea, E., Miller, B. J., Oliveira, C., Justicia, A., Griffith, J. K., Heaphy, C. M., Bernardo, M., & Kirkpatrick, B. (2013) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2012.11.009 · Cited by 84 · see citing works
Phillips, A. C., Robertson, T., Carroll, D., Der, G., Shiels, P. G., McGlynn, L., & Benzeval, M. (2013) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318289e6b5 · Cited by 55 · see citing works
McEwen, B. S. (2004) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2004.6.2/bmcewen · Cited by 54 · see citing works
Transcriptional regulation of corticotropin-releasing hormone gene in stress response
Zhou, J.-N., & Fang, H. (2018) · IBRO Reports · doi:10.1016/j.ibror.2018.08.003 · Cited by 36 · see citing works
- Authors
- Heuser, I.
- Affiliations
- Freie Universität Berlin (DE)
- Corresponding author
- Heuser, Isabella
- ORCID
- Heuser, Isabella
- Venue
- Maturitas
- Publisher
- Elsevier BV
- Published
- 2002-04
- Volume
- 41
- Pages
- 19-23
- ISSN
- 0378-5122 (ISSN-L)
- OpenAlex
- W1970991059
- Cited by
- 35
- References
- 16
- Citations by year
- 2025: 1 · 2024: 1 · 2021: 1 · 2020: 3 · 2019: 2 · 2018: 2 · 2017: 1 · 2015: 1 · 2014: 3 · 2013: 2 · 2012: 4
- FWCI
- 0.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Maturitas (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- depression, premature aging, endocrinology, sex differences, prevalence, mental illness
- MeSH terms
- Depression, Endocrine System, Female, Humans, Male, Menopause, Middle Aged, Syndrome, Osteoporosis, Postmenopausal, Aging, Premature
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