INTESTINAL (MESENTERIC) VASCULOPATHY I
Abstract
Intestinal vasculopathy is not rare, comprising about 1 per 1000 hospital admissions. Primary mesenteric vasculopathy causes cardiovascular disease, whereas secondary mesenteric ischemia causes extrinsic vascular compression or vascular trauma. Acute superior mesenteric arteriopathy is caused by a mesenteric embolus, thrombus, or vasospasm (i.e., nonocclusive vasculopathy). Acute superior mesenteric venopathy is caused by a thrombus, which is often associated with a hypercoagulopathy. The clinical presentation of both diseases is often subtle and nonspecific at an early stage and becomes overt and specific only when advanced and severe, when ischemia progresses to necrosis. The mortality of acute superior mesenteric arteriopathy is still very high, whereas superior mesenteric venopathy is less rapidly progressive and has a lower, but still significant, mortality. Early diagnosis and aggressive therapy significantly reduces the mortality of these life-threatening diseases.
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In most cases of SMA embolism, duodenum, proximal jejunum and transverse colon get spared as emboli lodge 6 to 8 cm beyond its origin, often beyond the origin of middle colic artery.
“In most cases of SMA embolism, duodenum, proximal jejunum and transverse colon get spared as emboli lodge 6 to 8 cm beyond its origin, often beyond the origin of middle colic artery.”
From Ischemic bowel disease in 2021. (2021) · cites this paper as [21]
Emboli lodge into the SMA more easily possibly because of its large diameter and its origin from the aorta at an acute angle.
“Emboli lodge into the SMA more easily possibly because of its large diameter and its origin from the aorta at an acute angle[21].”
From Ischemic bowel disease in 2021. (2021) · cites this paper as [21]
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- Authors
- Cappell, M. S.
- Affiliations
- Maimonides Medical Center (US)
- Corresponding author
- Cappell, Mitchell S.
- ORCID
- Cappell, Mitchell S.
- Venue
- Gastroenterology Clinics of North America
- Publisher
- Elsevier BV
- Published
- 1998-12
- Volume
- 27
- Issue
- 4
- Pages
- 783-825
- ISSN
- 0889-8553 (ISSN-L)
- OpenAlex
- W2765939434
- Cited by
- 127
- References
- 509
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 2 · 2021: 5 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 5 · 2016: 1 · 2015: 3 · 2014: 7 · 2013: 5 · 2012: 4
- FWCI
- 5.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Gastroenterology Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Surgery › Vascular anomalies and interventions
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Aortic Thrombus and Embolism
- Keywords
- mesenteric ischemia, mesenteric embolism, nonocclusive mesenteric ischemia, hypercoagulability, intestinal necrosis, mortality, early diagnosis
- MeSH terms
- Humans, Intestines, Ischemia, Mesenteric Vascular Occlusion, Mesenteric Veins, Vascular Diseases, Mesenteric Artery, Superior
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