The DOI matches its Crossref record; 67 of the 68 references it cites were found in a registry or an index.
MAP Kinase Translocates into the Nucleus of the Presynaptic Cell and Is Required for Long-Term Facilitation in Aplysia
Open accessAbstract
Long-term facilitation of the sensory to motor synapse in Aplysia requires gene expression. While some transcription factors involved in long-term facilitation are phosphorylated by PKA, others lack PKA sites but contain MAP Kinase (MAPK) phosphorylation sites. We now show that MAPK translocates into the nucleus of the presynaptic but not the postsynaptic cell during 5-HT-induced long-term facilitation. The presynaptic nuclear translocation of MAPK is also triggered by elevations in intracellular cAMP. Injection of anti-MAPK antibodies or of MAPK Kinase inhibitors into the presynaptic cell blocks long-term facilitation, without affecting basal synaptic transmission or short-term facilitation. Thus, MAPK appears to be specifically recruited and necessary for the long-term form of facilitation. This mechanism for long-term plasticity may be quite general: cAMP also activated MAPK in mouse hippocampal neurons, suggesting that MAPK may play a role in hippocampal long-term potentiation.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Two biochemical cascades required for LTF are those that mediate activation of protein kinase A (PKA)12–15 and the MAP kinase isoform termed extracellular signal-regulated kinase (ERK)16–18.”
From Computational design of enhanced learning protocols (2012) · cites this paper as [16]
Citations
Cites
A synaptic model of memory: long-term potentiation in the hippocampus
Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566
Marshall, C. J. (1995) · Cell · doi:10.1016/0092-8674(95)90401-8 · Cited by 3,906
Alessi, D. R., Cuenda, A., Cohen, P., Dudley, D. T., & Saltiel, A. R. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.46.27489 · Cited by 3,374
A synthetic inhibitor of the mitogen-activated protein kinase cascade.
Dudley, D. T., Pang, L., Decker, S. J., Bridges, A. J., & Saltiel, A. R. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.17.7686 · Cited by 2,679
Synaptic tagging and long-term potentiation
Frey, U., & Morris, R. G. M. (1997) · Nature · doi:10.1038/385533a0 · Cited by 1,736
Protein synthesis and memory: A review.
Davis, H. P., & Squire, L. R. (1984) · Psychological Bulletin · doi:10.1037/0033-2909.96.3.518 · Cited by 1,505
Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase
Xing, J. W., Ginty, D. D., & Greenberg, M. E. (1996) · Science · doi:10.1126/science.273.5277.959 · Cited by 1,246
Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons
Frey, U., Huang, Y.-Y., & Kandel, E. R. (1993) · Science · doi:10.1126/science.8389057 · Cited by 1,218
Self-citationAbel, T., Nguyen, P. V., Barad, M., Deuel, T. A. S., Kandel, E. R., & Bourtchouladze, R. (1997) · Cell · doi:10.1016/s0092-8674(00)81904-2 · Cited by 1,217
Self-citationcAMP Activates MAP Kinase and Elk-1 through a B-Raf- and Rap1-Dependent Pathway
Vossler, M. R., Yao, H. W., York, R. D., Pan, M., Rim, C. S., & Stork, P. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80184-1 · Cited by 1,044
Research works printed but not linked: 2
- Lisman, 1995, What does the nucleus know about memories?, J. NIH Res, 7, 43
- Sossin, 1996, Mechanisms for the generation of synapse specificity in long-term memory, Trends Neurosci, 19, 215
Cited by
Sorted by citations
Items 301–400 of 545
Sun, Z.-N., & Schacher, S. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-11-03991.1998 · Cited by 37
Pattern and predictability in memory formation: From molecular mechanisms to clinical relevance
Philips, G. T., Kopec, A. M., & Carew, T. J. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.05.003 · Cited by 33
Bae‐Gartz, I., Janoschek, R., Breuer, S., Schmitz, L., Hoffmann, T., Ferrari, N., Branik, L., Oberthuer, A., Kloppe, C.-S., Appel, S., et al. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00962 · Cited by 34
Shobe, J. L., Zhao, Y., Stough, S., Ye, X., Hsuan, V., Martin, K. C., & Carew, T. J. (2009) · Neuron · doi:10.1016/j.neuron.2008.10.049 · Cited by 33
Self-citationGiovannini, M. G., Pazzagli, M., Malmberg‐Aiello, P., Corte, L., Rakovska, A., Cerbai, F., Casamenti, F., & Pepeu, G. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.07.046 · Cited by 32
Swarnkar, S., Avchalumov, Y., Espadas, I., Grinman, E., Liu, X.-A., Raveendra, B., Zucca, A., Mediouni, S., Sadhu, A., Valente, S. T., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2021.109369 · Cited by 33
Saunders, C., Keefer, J. R., Bonner, C. A., & Limbird, L. E. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.37.24196 · Cited by 32
Lin, H., Bao, J., Ying, J., Walters, E. T., & Ambron, R. T. (2003) · Journal of Neurobiology · doi:10.1002/neu.10275 · Cited by 32
Cohen, J. E., Onyike, C. U., McElroy, V. L., Lin, A. H., & Abrams, T. W. (2003) · Journal of Neurophysiology · doi:10.1152/jn.01004.2002 · Cited by 32
Action Potentials: To the Nucleus and Beyond
Saha, R. N., & Dudek, S. M. (2008) · Experimental Biology and Medicine · doi:10.3181/0709-mr-241 · Cited by 31
Zhang, X., Daugherty, S. L., & de Groat, W. C. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00672.2010 · Cited by 31
A Multidisciplinary Approach to Learning and Memory in the Crab Neohelice (Chasmagnathus) granulata
Tomsic, D., & Romano, A. G. (2013) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-415823-8.00026-5 · Cited by 32
Endo, S., & Launey, T. (2003) · Neuropharmacology · doi:10.1016/s0028-3908(03)00210-7 · Cited by 31
The Central Noradrenaline System and Memory Consolidation
Kobayashi, K., & Yasoshima, Y. (2001) · The Neuroscientist · doi:10.1177/107385840100700506 · Cited by 32
Interactions of melatonin with various signaling pathways: implications for cancer therapy
Mihanfar, A., Yousefi, B., Azizzadeh, B., & Majidinia, M. (2022) · Cancer Cell International · doi:10.1186/s12935-022-02825-2 · Cited by 30
Lobster Attack Induces Sensitization in the Sea Hare, Aplysia californica
Watkins, A. J., Goldstein, D. A., Lee, L. C., Pepino, C. J., Tillett, S. L., Ross, F. E., Wilder, E. M., Zachary, V. A., & Wright, W. G. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1317-10.2010 · Cited by 29
Signaling from the Cytoplasm to the Nucleus in Striatal Medium-Sized Spiny Neurons
Matamales, M., & Girault, J. (2011) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2011.00037 · Cited by 37
Li, Q., Zhang, X., Hu, W., Liang, X., Zhang, F., Wang, L., Liu, Z., & Zhong, Y. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1520401113 · Cited by 31
Two mRNA-Binding Proteins Regulate the Distribution of Syntaxin mRNA inAplysiaSensory Neurons
Liu, J., Hu, J., Wu, F., Schwartz, J. H., & Schacher, S. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4917-05.2006 · Cited by 30
Sweatt, J. D., Schrader, L. A., Anderson, A. E., Varga, A. W., & Levy, M. (2002) · Molecular Neurobiology · doi:10.1385/mn:25:1:051 · Cited by 30
Sung, Y., & Ambron, R. T. (2004) · Neurological Research · doi:10.1179/016164104225013761 · Cited by 30
Synapse Number and Synaptic Efficacy Are Regulated by Presynaptic cAMP and Protein Kinase A
Munno, D. W., Prince, D. J., & Syed, N. I. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-10-04146.2003 · Cited by 29
Park, H., Lee, J., Lee, C., Kim, M., Chang, D., Kim, H., Lee, S., Lee, Y., & Kaang, B. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1989-05.2005 · Cited by 27
MAP kinases and their roles in pancreatic β-cells
Khoo, S., Gibson, T. B., Arnette, D., Lawrence, M. C., January, B., McGlynn, K., Vanderbilt, C. A., Griffen, S. C., German, M. S., & Cobb, M. H. (2004) · Cell Biochemistry and Biophysics · doi:10.1385/cbb:40:3:191 · Cited by 29
Genetic evidence for noradrenergic control of long-term memory consolidation
Kobayashi, K., & Kobayashi, T. (2001) · Brain and Development · doi:10.1016/s0387-7604(01)00329-1 · Cited by 29
Regulating actin dynamics in neuronal growth cones by ADF/cofilin and Rho family GTPases
Kuhn, T. B., Meberg, P. J., Brown, M. D., Bernstein, B. W., Minamide, L. S., Jensen, J. R., Okada, K., Soda, E. A., & Bamburg, J. R. (2000) · Journal of Neurobiology · doi:10.1002/1097-4695(200008)44:2 · Cited by 189
Squitti, R., Stefano, M. E. D., Edgar, D., & TOSCHI, G. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00660-5 · Cited by 29
Espadas, I., Wingfield, J. L., Nakahata, Y., Chanda, K., Grinman, E., Ghosh, I., Bauer, K. E., Raveendra, B., Kiebler, M. A., Yasuda, R., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-46972-8 · Cited by 28
Mapping Molecular Memory: Navigating the Cellular Pathways of Learning
Owen, G. R., & Brenner, E. (2012) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-012-9836-0 · Cited by 26
Bailey, C. H., Barco, Á., Hawkins, R. D., & Kandel, E. R. (2008) · Elsevier eBooks · doi:10.1016/b978-012370509-9.00191-1 · Cited by 28
Self-citationQiao, F., Gao, X., Li, Y., Cai, H.-Y., & Qi, J. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-140375 · Cited by 29
Smolen, P. D., Baxter, D. A., & Byrne, J. H. (2009) · Physical Review E · doi:10.1103/physreve.79.031902 · Cited by 27
Danilova, A. B., Kharchenko, O. A., Shevchenko, K. G., & Grinkevich, L. N. (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2010.00180 · Cited by 27
Sharker, M. R., Sukhan, Z. P., Kim, S. C., Lee, W. K., & Kho, K. H. (2019) · Molecular Biology Reports · doi:10.1007/s11033-019-05162-2 · Cited by 26
Fioravante, D., Liu, R., Netek, A. K., Cleary, L. J., & Byrne, J. H. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00604.2007 · Cited by 26
Bennett, P. C., Zhao, W., & Ng, K. T. (2001) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1999.3959 · Cited by 28
Dumitriu, B. C., Cohen, J. E., Wan, Q., Negroiu, A. M., & Abrams, T. W. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00642.2005 · Cited by 26
Lee, J.-A., Lee, S.-H., Lee, C., Chang, D.-J., Lee, Y., Kim, H., Cheang, Y.-H., Ko, H.-G., Lee, Y.-S., Jun, H., et al. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200512066 · Cited by 25
Self-citationMaharana, C., Sharma, K. P., & Sharma, S. K. (2013) · Scientific Reports · doi:10.1038/srep01103 · Cited by 27
Reconsolidation-induced memory persistence: Participation of late phase hippocampal ERK activation
Krawczyk, M. C., Navarro, N. M., Blake, M. G., Romano, A. G., Feld, M., & Boccia, M. M. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.06.013 · Cited by 26
MicroRNAs in Memory Processing
Fischbach, S., & Carew, T. J. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.007 · Cited by 25
Chronic activation of CREB and p90RSK in human epileptic hippocampus
Park, S. A., Kim, T. S., Choi, K. S., Park, H. J., Heo, K., & Lee, B. I. (2003) · Experimental & Molecular Medicine · doi:10.1038/emm.2003.48 · Cited by 25
Drosophila learning and memory: Recent progress and new approaches
Belvin, M. P., & Yin, J. C. P. (1997) · BioEssays · doi:10.1002/bies.950191207 · Cited by 25
Structural changes and the storage of long-term memory inAplysia
Bailey, C. H. (1999) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y99-072 · Cited by 26
Pérez‐Gómez, A., & Tasker, R. A. (2013) · BMC Neuroscience · doi:10.1186/1471-2202-14-72 · Cited by 24
Michel, M., Green, C. L., Gardner, J. S., Organ, C. L., & Lyons, L. C. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.6264-11.2012 · Cited by 24
Coregulation of Glutamate Uptake and Long-Term Sensitization inAplysia
Khabour, O. F., Levenson, J. M., Lyons, L. C., Kategaya, L. S., Chin, J., Byrne, J. H., & Eskin, A. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2167-04.2004 · Cited by 24
Liu, R., Zhang, Y., Smolen, P. D., Cleary, L. J., & Byrne, J. H. (2020) · Scientific Reports · doi:10.1038/s41598-020-57484-y · Cited by 25
Ye, X., Shobe, J. L., Sharma, S. K., Marina, A., & Carew, T. J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808110105 · Cited by 24
Crow, T., Xue‐Bian, J., Siddiqi, V., & Neary, J. T. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00404.x · Cited by 25
Bolyard, L. A., Looy, J. W. V., & Vasko, M. R. (2000) · Pain · doi:10.1016/s0304-3959(00)00341-9 · Cited by 24
Sebastian, C., Eßeling, K., & Horn, E. R. (2000) · Journal of Neurobiology · doi:10.1002/1097-4695(200101)46:1 · Cited by 34
Dyer, J. R., & Sossin, W. S. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0750872.x · Cited by 24
Ramírez, R. R., Gandhi, C. C., Muzzio, I. A., & Matzel, L. D. (1998) · Learning & Memory · doi:10.1101/lm.4.6.462 · Cited by 24
Degradation of Transcriptional Repressor ATF4 during Long-Term Synaptic Plasticity
Smith, S. G., Haynes, K. A., & Hegde, A. N. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228543 · Cited by 22
Gomi, F. (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2010.00017 · Cited by 24
Why behavioral neuroscience still needs diversity?: A curious case of a persistent need
Mathuru, A. S., Libersat, F., Vyas, A., & Teseo, S. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.06.021 · Cited by 23
Regulation of ERK Kinase by MEK1 Kinase Inhibition in the Brain
Tassin, T. C., Benavides, D. R., Plattner, F., Nishi, A., & Bibb, J. A. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.654897 · Cited by 22
Acceleration of K+ channel inactivation by MEK inhibitor U0126
Yuan, L., Chen, X., Kunjilwar, K. K., Pfaffinger, P. J., & Johnston, D. (2005) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00206.2005 · Cited by 22
Synaptic Functions of Invertebrate Varicosities: What Molecular Mechanisms Lie Beneath
Giachello, C. N., Montarolo, P. G., & Ghirardi, M. (2012) · Neural Plasticity · doi:10.1155/2012/670821 · Cited by 21
Ghirardi, M., Benfenati, F., Giovedı̀, S., Fiumara, F., Milanese, C., & Montarolo, P. G. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5671-03.2004 · Cited by 22
Schacher, S., Wu, F., Sun, Z., & Wang, D. (2000) · Journal of Neurobiology · doi:10.1002/1097-4695(20001115)45:3 · Cited by 21
Kopec, A. M., & Carew, T. J. (2013) · Learning & Memory · doi:10.1101/lm.031377.113 · Cited by 24
Protein trafficking from synapse to nucleus in control of activity-dependent gene expression
Kaushik, R., Grochowska, K. M., Butnaru, I., & Kreutz, M. R. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.09.011 · Cited by 20
Fulton, D. J., Kemenes, I., Andrew, R., & Benjamin, P. R. (2008) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2008.08.006 · Cited by 20
Song, D. B., Chan, R. H. M., Robinson, B. S., Marmarelis, V. Z., Opriș, I. C., Hampson, R. E., Deadwyler, S. A., & Berger, T. W. (2014) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2014.09.023 · Cited by 20
Suzuki, S., Zhou, H., Neumaier, J. F., & Pham, T. A. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21424 · Cited by 22
Intrahippocampal Wortmannin Infusion Enhances Long-Term Spatial and Contextual MemoriesPreprint
Dash, P. K., Mach, S. A., Blum, S., & Moore, A. N. (2002) · Learning & Memory · doi:10.1101/lm.50002 · Cited by 20
Understanding intellectual disability through RASopathies
Martín, A. S., & Pagani, M. R. (2014) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2014.05.003 · Cited by 24
Krawczyk, M. C., Blake, M. G., Baratti, C. M., Romano, A. G., Boccia, M. M., & Feld, M. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.03.019 · Cited by 19
Studies on Aplysia neurons suggest treatments for chronic human disorders
Abrams, T. W. (2012) · Current Biology · doi:10.1016/j.cub.2012.08.011 · Cited by 19
Grinkevich, L. N., Lisachev, P. D., Kharchenko, O. A., & Vasil’ev, G. V. (2007) · Brain Research · doi:10.1016/j.brainres.2007.08.029 · Cited by 19
Kharchenko, O. A., Grinkevich, V. V., Vorobiova, O. V., & Grinkevich, L. N. (2010) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2010.05.002 · Cited by 19
Isensee, J., Schild, C., Schwede, F., & Hucho, T. B. (2017) · Journal of Cell Science · doi:10.1242/jcs.197327 · Cited by 19
Targowska‐Duda, K. M., Wnorowski, A., Budzyńska, B., Jóźwiak, K., Biała, G., & Arias, H. R. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.01.002 · Cited by 19
Targeting Genes and Proteins in the Analysis of Learning and Memory: Caveats and Future Directions
Gerlai, R. T. (2000) · Reviews in the Neurosciences · doi:10.1515/revneuro.2000.11.1.15 · Cited by 19
Modulation of Excitability inAplysiaTail Sensory Neurons by Tyrosine Kinases
Purcell, A. L., & Carew, T. J. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.6.2398 · Cited by 18
An assay of behavioral plasticity in Drosophila larvae
Min, V. A., & Condron, B. G. (2005) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2004.11.022 · Cited by 18
Dyer, J. R., Manseau, F., Castellucci, V. F., & Sossin, W. S. (2003) · Neuroscience · doi:10.1016/s0306-4522(02)00566-3 · Cited by 18
Shobe, J. L., Philips, G. T., & Carew, T. J. (2016) · Learning & Memory · doi:10.1101/lm.040915.115 · Cited by 18
Potent block of potassium channels by MEK inhibitor U0126 in primary cultures and brain slices
Wang, J., Long, C., Li, K., Xu, H., Yuan, L., & Wu, G. (2018) · Scientific Reports · doi:10.1038/s41598-018-27235-1 · Cited by 18
Kansha, M., Nagata, T., Irita, K., & Takahashi, S. (1999) · Anesthesiology · doi:10.1097/00000542-199912000-00034 · Cited by 17
Molluscan neurons in culture: shedding light on synapse formation and plasticity
Schmold, N., & Syed, N. I. (2012) · Journal of Molecular Histology · doi:10.1007/s10735-012-9398-y · Cited by 16
Krawczyk, M. C., Millan, J., Blake, M. G., Feld, M., & Boccia, M. M. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00095 · Cited by 16
Zhang, Y., Smolen, P. D., Cleary, L. J., & Byrne, J. H. (2021) · Scientific Reports · doi:10.1038/s41598-021-94393-0 · Cited by 15
Distribution of ras guanyl releasing protein (RasGRP) mRNA in the adult rat central nervous system
Pierret, P., Dunn, R. J., Djordjevic, B., Stone, J. C., & Richardson, P. M. (2000) · Journal of Neurocytology · doi:10.1023/a:1007245728751 · Cited by 16
Giovannini, M. G. (2002) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(02)45035-5 · Cited by 16
Forskolin Induces NMDA Receptor-Dependent Potentiation at a Central Synapse in the Leech
Grey, K. B., & Burrell, B. D. (2008) · Journal of Neurophysiology · doi:10.1152/jn.00010.2008 · Cited by 16
Protein targeting in the analysis of learning and memory: a potential alternative to gene targeting
Gerlai, R. T., Williams, S. P., Cairns, B., van Bruggen, N., Moran, P., Shih, A., Caras, I. W., Sauer, H., PHILLIPS, H. S., & Winslow, J. W. (1998) · Experimental Brain Research · doi:10.1007/s002210050541 · Cited by 16
Zhu, Y., & Parada, L. F. (2001) · Nature Genetics · doi:10.1038/86835 · Cited by 16
Zhang, L., Jie, C., Obie, C., Abidi, F., Schwartz, C. E., Stevenson, R. E., Valle, D. L., & Wang, T. (2007) · Genome Research · doi:10.1101/gr.5336307 · Cited by 16
Zhou, L., Zhang, Y., Liu, R.-Y., Smolen, P., Cleary, L. J., & Byrne, J. H. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.3330-14.2015 · Cited by 14
PolyADP‐ribose polymerase‐1 (PARP‐1) and the evolution of learning and memory
Sung, Y., & Ambron, R. T. (2004) · BioEssays · doi:10.1002/bies.20164 · Cited by 15
Üre, A., & Altrup, U. (2005) · Neuroscience Letters · doi:10.1016/j.neulet.2005.08.045 · Cited by 15
Connecting model species to nature: predator-induced long-term sensitization in Aplysia californicaPreprint
Mason, M. J., Watkins, A. J., Wakabayashi, J., Buechler, J., Pepino, C., Brown, M. L., & Wright, W. G. (2014) · Learning & Memory · doi:10.1101/lm.034330.114 · Cited by 15
ERK signaling is required for eye-specific retino-geniculate segregation
Naska, S., Cenni, M. C., Menna, E., & Maffei, L. (2004) · Development · doi:10.1242/dev.01212 · Cited by 14
Pre-LTP requires extracellular signal-regulated kinase in the ACC
Yamanaka, M., Tian, Z., Darvish-Ghane, S., & Zhuo, M. (2016) · Molecular Pain · doi:10.1177/1744806916647373 · Cited by 15
Zhang, Y., Smolen, P. D., Baxter, D. A., & Byrne, J. H. (2017) · eNeuro · doi:10.1523/eneuro.0373-16.2017 · Cited by 12
Matamales, M. (2012) · F1000Research · doi:10.12688/f1000research.1-69.v1 · Cited by 14
Phosphorylation of eIF4E at a Conserved Serine in Aplysia
Dyer, J. R., Pepio, A. M., Yanow, S. K., & Sossin, W. S. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.45.29469 · Cited by 14
Metadata
- Authors
- Martin, K. C., Michael, D., Rose, J. C., Barad, M., Casadio, A., Zhu, H., & Kandel, E. R.
- Affiliations
- Howard Hughes Medical Institute (US)
- Columbia University Irving Medical Center (US)
- Corresponding author
- Kandel, Eric R
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 1997-06
- Volume
- 18
- Issue
- 6
- Pages
- 899-912
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2066592391
- Cited by
- 545
- References
- 68
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 8 · 2023: 5 · 2022: 9 · 2021: 9 · 2020: 9 · 2019: 11 · 2018: 13 · 2017: 14 · 2016: 13 · 2015: 14 · 2014: 16 · 2013: 16 · 2012: 14
- FWCI
- 16.93
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Neuron (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
- Keywords
- mitogen-activated protein kinase, nuclear translocation, long-term facilitation, Aplysia, serotonin, cyclic AMP, synaptic plasticity, gene expression, hippocampal long-term potentiation
- MeSH terms
- Cyclic AMP, Amino Acid Sequence, Animals, Aplysia, Cell Compartmentation, Cell Nucleus, Cells, Cultured, Enzyme Inhibitors, Flavonoids, Colforsin, Hippocampus, Molecular Sequence Data, Synaptic Transmission, Neuronal Plasticity, Neurons, Afferent, Peptides, Protein-Tyrosine Kinases, Serotonin, Synapses, Protein Serine-Threonine Kinases, Presynaptic Terminals, Long-Term Potentiation, Calcium-Calmodulin-Dependent Protein Kinases, Mitogen-Activated Protein Kinase Kinases, MAP Kinase Kinase 1
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review