The DOI matches its Crossref record; 48 of the 49 references it cites were found in a registry or an index.
Piccolo, a Presynaptic Zinc Finger Protein Structurally Related to Bassoon
Open accessAbstract
Piccolo is a novel component of the presynaptic cytoskeletal matrix (PCM) assembled at the active zone of neurotransmitter release. Analysis of its primary structure reveals that Piccolo is a multidomain zinc finger protein structurally related to Bassoon, another PCM protein. Both proteins were found to be shared components of glutamatergic and GABAergic CNS synapses but not of the cholinergic neuromuscular junction. The Piccolo zinc fingers were found to interact with the dual prenylated rab3A and VAMP2/Synaptobrevin II receptor PRA1. We show that PRA1 is a synaptic vesicle-associated protein that is colocalized with Piccolo in nerve terminals of hippocampal primary neurons. These data suggest that Piccolo plays a role in the trafficking of synaptic vesicles (SVs) at the active zone.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In addition to these five core active zone proteins, piccolo and bassoon (two large homologous proteins) are associated in vertebrates with active zones (tom Dieck et al., 1998; Wang et al., 1999; Fenster et al., 2000; Limbach et al., 2011), and proteins related to C. elegans SYD-1 are important for the assembly of active zones in invertebrates (Hallam et al., 2002; Patel et al., 2006; Owald et al”
From The Presynaptic Active Zone (2012) · cites this paper as Fenster et al., 2000
Citations
Cites
The synaptic vesicle cycle: a cascade of protein–protein interactions
Südhof, T. C. (1995) · Nature · doi:10.1038/375645a0 · Cited by 1,991
Coiled coils: new structures and new functions
Lupas, A. N. (1996) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)10052-9 · Cited by 1,321
At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells
Kozak, M. (1987) · Journal of Molecular Biology · doi:10.1016/0022-2836(87)90418-9 · Cited by 1,182
Nagase, T. (1998) · DNA Research · doi:10.1093/dnares/5.1.31 · Cited by 844
Balch, W. E., Dunphy, W. G., Braell, W. A., & Rothman, J. E. (1984) · Cell · doi:10.1016/0092-8674(84)90019-9 · Cited by 696
Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion
Wang, Y., Okamoto, M., Schmitz, F., Hofmann, K., & Südhof, T. C. (1997) · Nature · doi:10.1038/41580 · Cited by 684
Natural history of Williams syndrome: Physical characteristics
Morris, C. A., Demsey, S. A., Leonard, C. O., Dilts, C., & Blackburn, B. L. (1988) · The Journal of Pediatrics · doi:10.1016/s0022-3476(88)80272-5 · Cited by 670
Distinct pools of synaptic vesicles in neurotransmitter release
Pieribone, V. A., Shupliakov, O., Brodin, L., Hilfiker, S., Czernik, A. J., & Greengard, P. (1995) · Nature · doi:10.1038/375493a0 · Cited by 532
The cytoskeletal architecture of the presynaptic terminal and molecular structure of synapsin 1.
Hirokawa, N., Sobue, K., Kanda, K., Harada, A., & Yorifuji, H. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.108.1.111 · Cited by 501
PDZ Proteins Organize Synaptic Signaling Pathways
Craven, S. E., & Bredt, D. S. (1998) · Cell · doi:10.1016/s0092-8674(00)81179-4 · Cited by 494
Cited by
Sorted by citations
Short-Term Synaptic Plasticity
Zucker, R. S., & Regehr, W. G. (2002) · Annual Review of Physiology · doi:10.1146/annurev.physiol.64.092501.114547 · Cited by 5,068
Südhof, T. C. (2012) · Neuron · doi:10.1016/j.neuron.2012.06.012 · Cited by 1,062
Wagh, D. A., Rasse, T. M., Asan, E., Hofbauer, A., Schwenkert, I., Dürrbeck, H., Buchner, S., Dabauvalle, M.-C., Schmidt, M., Qin, G., et al. (2006) · Neuron · doi:10.1016/j.neuron.2006.02.008 · Cited by 908
Superresolution Imaging of Chemical Synapses in the Brain
Dani, A., Huang, B., Bergan, J. F., Dulac, C. G., & Zhuang, X. (2010) · Neuron · doi:10.1016/j.neuron.2010.11.021 · Cited by 748
Synaptic Vesicle ExocytosisPreprint
Südhof, T. C., & Rizo, J. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005637 · Cited by 539
Assembly of New Individual Excitatory Synapses
Friedman, H., Bresler, T., Garner, C. C., & Ziv, N. E. (2000) · Neuron · doi:10.1016/s0896-6273(00)00009-x · Cited by 499
Self-citationTargeting Rab GTPases to distinct membrane compartments
Pfeffer, S. R., & Aivazian, D. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1500 · Cited by 462
Dick, O., Dieck, S. T., Altrock, W. D., Ammermüller, J., Weiler, R., Garner, C., Gundelfinger, E., & Brandstätter, J. (2003) · Neuron · doi:10.1016/s0896-6273(03)00086-2 · Cited by 453
Self-citationFunctional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming
Betz, A., Thakur, P., Junge, H. J., Ashery, U., Rhee, J.-S., Scheuss, V., Rosenmund, C., Rettig, J., & Brose, N. (2001) · Neuron · doi:10.1016/s0896-6273(01)00272-0 · Cited by 425
Assembling the Presynaptic Active Zone
Zhai, R. G., Vardinon-Friedman, H., Cases-Langhoff, C., Becker, B., Gundelfinger, E. D., Ziv, N. E., & Garner, C. C. (2001) · Neuron · doi:10.1016/s0896-6273(01)00185-4 · Cited by 424
Self-citationChlorotoxin Inhibits Glioma Cell Invasion via Matrix Metalloproteinase-2
Deshane, J. S., Garner, C. C., & Sontheimer, H. W. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m205662200 · Cited by 412
Self-citationMolecular dissection of the photoreceptor ribbon synapse
Dieck, S. T., Altrock, W. D., Kessels, M. M., Qualmann, B., Regus‐Leidig, H., Brauner, D., Fejtová, A., Bracko, O., Gundelfinger, E. D., & Brandstätter, J. H. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200408157 · Cited by 409
Self-citationHighwire Regulates Synaptic Growth in Drosophila
Wan, H. I., DiAntonio, A., Fetter, R. D., Bergstrom, K., Strauß, R., & Goodman, C. S. (2000) · Neuron · doi:10.1016/s0896-6273(00)81166-6 · Cited by 403
Unitary Assembly of Presynaptic Active Zones from Piccolo-Bassoon Transport Vesicles
Shapira, M., Zhai, R. G., Dresbach, T., Bresler, T., Torres, V. I., Gundelfinger, E. D., Ziv, N. E., & Garner, C. C. (2003) · Neuron · doi:10.1016/s0896-6273(03)00207-1 · Cited by 363
Self-citationDiversification of synaptic strength: presynaptic elements
Atwood, H. L., & Karunanithi, S. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn876 · Cited by 346
Vosseller, K., Trinidad, J. C., Chalkley, R. J., Specht, C. G., Thalhammer, A., Lynn, A. J., Snedecor, J., Guan, S., Medzihradszky, K. F., Maltby, D. A., et al. (2006) · Molecular & Cellular Proteomics · doi:10.1074/mcp.t500040-mcp200 · Cited by 346
Molecular organization of the presynaptic active zone
Schoch, S., & Gundelfinger, E. D. (2006) · Cell and Tissue Research · doi:10.1007/s00441-006-0244-y · Cited by 346
Self-citationC ELL B IOLOGY OF THE P RESYNAPTIC T ERMINAL
Murthy, V. N., & Camilli, P. V. D. (2003) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131445 · Cited by 337
Three-Dimensional Architecture of Presynaptic Terminal Cytomatrix
Siksou, L., Rostaing, P., Lechaire, J., Boudier, T., Ohtsuka, T., Fejtová, A., Kao, H., Greengard, P., Gundelfinger, E. D., Triller, A., et al. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1773-07.2007 · Cited by 340
Self-citationPhosphoinositides in membrane traffic at the synapse
Cremona, O., & Camilli, P. V. D. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.6.1041 · Cited by 324
Ohtsuka, T., Takao‐Rikitsu, E., Inoue, E., Inoue, M., Takeuchi, M., Matsubara, K., Deguchi‐Tawarada, M., Satoh, K., Morimoto, K., Nakanishi, H., et al. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200202083 · Cited by 298
The Architecture of the Active Zone in the Presynaptic Nerve Terminal
Zhai, R. G., & Bellen, H. J. (2004) · Physiology · doi:10.1152/physiol.00014.2004 · Cited by 305
Self-citationActin-Dependent Regulation of Neurotransmitter Release at Central Synapses
Morales, M., Colicos, M. A., & Goda, Y. (2000) · Neuron · doi:10.1016/s0896-6273(00)00064-7 · Cited by 300
Temporal and spatial coordination of exocytosis and endocytosis
Gundelfinger, E. D., Kessels, M. M., & Qualmann, B. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1016 · Cited by 272
Self-citationStages of Synapse Development Defined by Dependence on F-Actin
Zhang, W., & Benson, D. L. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05169.2001 · Cited by 262
Altrock, W. D., tom Dieck, S., Sokolov, M., Meyer, A. C., Sigler, A., Brakebusch, C., Fässler, R., Richter, K., Boeckers, T. M., Potschka, H., et al. (2003) · Neuron · doi:10.1016/s0896-6273(03)00088-6 · Cited by 258
Self-citationZhen, M., Huang, X., Bamber, B. A., & Jin, Y. (2000) · Neuron · doi:10.1016/s0896-6273(00)81167-8 · Cited by 235
Onset coding is degraded in auditory nerve fibers from mutant mice lacking synaptic ribbons
Buran, B., Strenzke, N., Neef, A., Gundelfinger, E., Moser, T., & Liberman, M. C. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0389-10.2010 · Cited by 200
Self-citationTakao-Rikitsu, E., Mochida, S., Inoue, E., Deguchi-Tawarada, M., Inoue, M., Ohtsuka, T., & Takai, Y. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200307101 · Cited by 221
Molecular determinants of presynaptic active zones
Garner, C. C., Kindler, S., & Gundelfinger, E. D. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00093-3 · Cited by 221
Self-citationThe presynaptic cytomatrix of brain synapses
Dresbach, T., Qualmann, B., Kessels, M. M., Garner, C. C., & Gundelfinger, E. D. (2001) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000781 · Cited by 224
Self-citationDirect Interaction of the Rab3 Effector RIM with Ca2+Channels, SNAP-25, and Synaptotagmin*
Coppola, T., Magnin-Lüthi, S., Perret-Menoud, V., Gattesco, S., Schiavo, G., & Regazzi, R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100929200 · Cited by 216
Association of the Kinesin Motor KIF1A with the Multimodular Protein Liprin-α
Shin, H., Wyszynski, M. W., Huh, K. H., Valtschanoff, J. G., Lee, J.-R., Ko, J., Streuli, M., Weinberg, R. J., Sheng, M., & Kim, E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211874200 · Cited by 211
Sensory Processing at Ribbon Synapses in the Retina and the Cochlea
Moser, T., Grabner, C. P., & Schmitz, F. (2019) · Physiological Reviews · doi:10.1152/physrev.00026.2018 · Cited by 215
Molecular mechanisms of CNS synaptogenesis
Garner, C. C., Zhai, R. G., Gundelfinger, E. D., & Ziv, N. E. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02152-5 · Cited by 218
Self-citationA role for ion channels in glioma cell invasion
McFerrin, M. B., & Sontheimer, H. W. (2005) · Neuron Glia Biology · doi:10.1017/s1740925x06000044 · Cited by 205
Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone
Gundelfinger, E. D., Reissner, C., & Garner, C. C. (2016) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2015.00019 · Cited by 203
Self-citationMukherjee, K., Yang, X., Gerber, S. H., Kwon, H.-B., Ho, A., Castillo, P. E., Liu, X., & Südhof, T. C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002307107 · Cited by 195
The Molecular Machinery of Neurotransmitter Release (Nobel Lecture)
Südhof, T. C. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201406359 · Cited by 196
Ko, J., Na, M., Kim, S.-H., Lee, J.-R., & Kim, E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307561200 · Cited by 187
The SAD-1 Kinase Regulates Presynaptic Vesicle Clustering and Axon Termination
Crump, J. G., Zhen, M., Jin, Y., & Bargmann, C. I. (2001) · Neuron · doi:10.1016/s0896-6273(01)00184-2 · Cited by 184
Shibasaki, T., Sunaga, Y., Fujimoto, K., Kashima, Y., & Seino, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m309068200 · Cited by 175
Interaction between Liprin-α and GIT1 Is Required for AMPA Receptor Targeting
Ko, J., Kim, S.-H., Valtschanoff, J. G., Shin, H., Lee, J.-R., Sheng, M., Premont, R. T., Weinberg, R. J., & Kim, E. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-05-01667.2003 · Cited by 161
Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis
Leal‐Ortiz, S., Waites, C. L., Terry-Lorenzo, R. T., Zamorano, P. L., Gundelfinger, E. D., & Garner, C. C. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200711167 · Cited by 159
Self-citationBassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation
Waites, C. L., Leal‐Ortiz, S., Okerlund, N. D., Dalke, H., Fejtová, A., Altrock, W. D., Gundelfinger, E. D., & Garner, C. C. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.27 · Cited by 156
Self-citationHow to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs
Acuna, C., Liu, X., & Südhof, T. C. (2016) · Neuron · doi:10.1016/j.neuron.2016.07.042 · Cited by 158
Dick, O., Hack, I., Altrock, W. D., Garner, C. C., Gundelfinger, E. D., & Brandstätter, J. H. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1344 · Cited by 153
Self-citationDistinct Initial SNARE Configurations Underlying the Diversity of Exocytosis
Kasai, H., Takahashi, N., & Tokumaru, H. (2012) · Physiological Reviews · doi:10.1152/physrev.00007.2012 · Cited by 150
The actin cytoskeleton and neurotransmitter release: An overview
Doussau, F. (2000) · Biochimie · doi:10.1016/s0300-9084(00)00217-0 · Cited by 151
Presynaptic Clustering of mGluR7a Requires the PICK1 PDZ Domain Binding Site
Boudin, H., Doan, A., Xia, J., Shigemoto, R., Huganir, R. L., Worley, P. F., & Craig, A. M. (2000) · Neuron · doi:10.1016/s0896-6273(00)00127-6 · Cited by 149
Molecular mechanisms of active zone function
Rosenmund, C., Rettig, J., & Brose, N. (2003) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2003.09.011 · Cited by 144
Molecular heterogeneity of central synapses: afferent and target regulation
Craig, A. M., & Boudin, H. (2001) · Nature Neuroscience · doi:10.1038/88388 · Cited by 142
Boyl, P. P., Nardo, A. D., Mulle, C., Sassoé‐Pognetto, M., Panzanelli, P., Mele, A., Kneussel, M., Costantini, V. J. A., Perlas, E., Massimi, M., et al. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601737 · Cited by 140
Kim, S.-H., Ko, J., Shin, H., Lee, J.-R., Lim, C., Han, J., Altrock, W. D., Garner, C. C., Gundelfinger, E. D., Premont, R. T., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212287200 · Cited by 140
Self-citationDocking of Secretory Vesicles Is Syntaxin Dependent
de Wit, H., Cornelisse, L. N., Toonen, R. F. G., & Verhage, M. (2006) · PLoS ONE · doi:10.1371/journal.pone.0000126 · Cited by 130
The molecular machinery of synaptic vesicle exocytosis
Li, L., & Chin, L. (2003) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-2240-7 · Cited by 129
Shin, O., Han, W., Wang, Y., & Südhof, T. C. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407305200 · Cited by 126
Relating structure and function of inner hair cell ribbon synapses
Wichmann, C., & Moser, T. (2015) · Cell and Tissue Research · doi:10.1007/s00441-014-2102-7 · Cited by 123
Ruiz, R., Cano, R., Casañas, J. J., Gaffield, M. A., Betz, W. J., & Tabares, L. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4663-10.2011 · Cited by 121
Fakih, D., Zhao, Z., Nicolle, P., Reboussin, É., Joubert, F., Luzu, J., Labbé, A., Rostène, W. H., Baudouin, C., Parsadaniantz, S. M., et al. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1656-4 · Cited by 126
Structural and functional diversity generated by alternative mRNA splicing
Stetefeld, J., & Rüegg, M. A. (2005) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2005.07.001 · Cited by 117
Profilin1 biology and its mutation, actin(g) in disease
Alkam, D., Feldman, E. Z., Singh, A., & Kiaei, M. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2372-1 · Cited by 114
Voltage-Gated Calcium Channels: Key Players in Sensory Coding in the Retina and the Inner Ear
Pangršič, T., Singer, J. H., & Koschak, A. (2018) · Physiological Reviews · doi:10.1152/physrev.00030.2017 · Cited by 116
Dresbach, T., Hempelmann, A., Spilker, C., Dieck, S. T., Altrock, W. D., Zuschratter, W., Garner, C. C., & Gundelfinger, E. D. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00015-0 · Cited by 113
Self-citationInoue, E., Mochida, S., Takagi, H., Higa, S., Deguchi‐Tawarada, M., Takao‐Rikitsu, E., Inoue, M., Yao, I., Takeuchi, K., Kitajima, I., et al. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.018 · Cited by 115
Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon
Fejtová, A., Davydova, D., Bischof, F., Lazarevic, V., Altrock, W. D., Romorini, S., Schöne, C., Zuschratter, W., Kreutz, M. R., Garner, C. C., et al. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200807155 · Cited by 113
Self-citationAssembly of Active Zone Precursor Vesicles
Dresbach, T., Torres, V. I., Wittenmayer, N., Altrock, W. D., Zamorano, P. L., Zuschratter, W., Nawrotzki, R., Ziv, N. E., Garner, C. C., & Gundelfinger, E. D. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m508784200 · Cited by 107
Self-citationAndrews-Zwilling, Y. S., Kawabe, H., Reim, K., Varoqueaux, F., & Brose, N. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601421200 · Cited by 105
Fenster, S. D., Kessels, M. M., Qualmann, B., Chung, W. J., Nash, J. E., Gundelfinger, E. D., & Garner, C. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210792200 · Cited by 107
Self-citationBader, M. F., Doussau, F., Chasserot‐Golaz, S., Vitale, N., & Gasman, S. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2004.09.028 · Cited by 102
A conformational switch in the Piccolo C2A domain regulated by alternative splicing
Garcia, J. M., Gerber, S. H., Sugita, S., Südhof, T., & Rizo, J. (2004) · Nature Structural &Molecular Biology · doi:10.1038/nsmb707 · Cited by 105
Prenylated Rab Acceptor Protein Is a Receptor for Prenylated Small GTPases
Figueroa‐Romero, C., Taylor, J., & Vojtek, A. B. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101763200 · Cited by 97
Wang, X., Hu, B., Zieba, A., Neumann, N. G., Kasper-Sonnenberg, M., Honsbein, A., Hultqvist, G., Conze, T., Witt, W., Limbach, C., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1255-09.2009 · Cited by 96
Limbach, C., Laue, M. M., Wang, X., Hu, B., Thiede, N., Hultqvist, G., & Kilimann, M. W. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1101707108 · Cited by 92
Cellular Mechanisms for the Biogenesis and Transport of Synaptic and Dense-Core Vesicles
Gondré‐Lewis, M. C., Park, J. J., & Loh, Y. P. (2012) · International review of cytology · doi:10.1016/b978-0-12-394310-1.00002-3 · Cited by 96
LAR, liprin α and the regulation of active zone morphogenesis
Stryker, E., & Johnson, K. G. (2007) · Journal of Cell Science · doi:10.1242/jcs.03491 · Cited by 94
Andrés‐Benito, P., Moreno, J. R., Aso, E., Povedano, M., & Ferrer, I. (2017) · Aging · doi:10.18632/aging.101195 · Cited by 92
Deguchi‐Tawarada, M., Inoue, E., Takao‐Rikitsu, E., Inoue, M., Ohtsuka, T., & Takai, Y. (2004) · Genes to Cells · doi:10.1111/j.1356-9597.2004.00697.x · Cited by 92
Puthanveettil, S. V., Monje, F. J., Miniaci, M. C., Choi, Y., Karl, K. A., Khandros, E., Gawinowicz, M. A., Sheetz, M. P., & Kandel, E. R. (2008) · Cell · doi:10.1016/j.cell.2008.11.003 · Cited by 89
The role of laminins in the organization and function of neuromuscular junctions
Rogers, R. S., & Nishimune, H. (2016) · Matrix Biology · doi:10.1016/j.matbio.2016.08.008 · Cited by 93
Longhena, F., Faustini, G., Spillantini, M. G., & Bellucci, A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20010141 · Cited by 89
Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo
Ivanova, D., Dirks, A., Montenegro‐Venegas, C., Schöne, C., Altrock, W. D., Marini, C., Frischknecht, R., Schanze, D., Zenker, M., Gundelfinger, E. D., et al. (2015) · The EMBO Journal · doi:10.15252/embj.201488796 · Cited by 91
Self-citationShort-distance vesicle transport via phase separation
Qiu, H., Wu, X., Ma, X., Li, S., Cai, Q., Ganzella, M., Ge, L., Zhang, H., & Zhang, M. (2024) · Cell · doi:10.1016/j.cell.2024.03.003 · Cited by 88
Piccolo Regulates the Dynamic Assembly of Presynaptic F-Actin
Waites, C. L., Leal‐Ortiz, S., Andlauer, T. F. M., Sigrist, S. J., & Garner, C. C. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.1835-11.2011 · Cited by 89
Self-citationSustaining rapid vesicular release at active zones: potential roles for vesicle tethering
Hallermann, S., & Silver, R. A. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.10.001 · Cited by 88
Regus‐Leidig, H., Ott, C., Löhner, M., Atorf, J., Fuchs, M., Sedmak, T., Kremers, J., Fejtová, A., Gundelfinger, E. D., & Brandstätter, J. H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070373 · Cited by 82
Self-citationN., R. M. N., Bulankina, A. V., Khimich, D., Giese, A., & Moser, T. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.05.057 · Cited by 79
Molecular Genetic Findings in Suicidal Behavior: What is Beyond the Serotonergic System?
Rujescu, D., Thalmeier, A., Möller, H., Bronisch, T., & Giegling, I. (2006) · Archives of Suicide Research · doi:10.1080/13811110600897317 · Cited by 79
PRA Isoforms Are Targeted to Distinct Membrane Compartments
Abdul‐Ghani, M., Gougeon, P., Prosser, D. C., DaSilva, L. F., & Ngsee, J. K. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009073200 · Cited by 79
CAST and ELKS proteins: structural and functional determinants of the presynaptic active zone
Hida, Y., & Ohtsuka, T. (2010) · The Journal of Biochemistry · doi:10.1093/jb/mvq065 · Cited by 85
Intra-axonal Synthesis of SNAP25 Is Required for the Formation of Presynaptic Terminals
Batista, A. F. R., Martínez, J. C., & Hengst, U. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.08.097 · Cited by 78
Coupling exo- and endocytosis: An essential role for PIP2 at the synapse
Koch, M., & Holt, M. G. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2012.02.008 · Cited by 87
Active zone density is conserved during synaptic growth but impaired in aged mice
Chen, J., Mizushige, T., & Nishimune, H. (2012) · The Journal of comparative neurology · doi:10.1002/cne.22764 · Cited by 78
Ribbon Synapses and Visual Processing in the Retina
Lagnado, L., & Schmitz, F. (2015) · Annual Review of Vision Science · doi:10.1146/annurev-vision-082114-035709 · Cited by 78
Tobin, V. A., Leng, G., & Ludwig, M. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00261 · Cited by 70
Kim, J. H., Franck, J., Kang, T., Heinsen, H., Ravid, R., Ferrer, I., Cheon, M. H., Lee, J., Yoo, J. S., Steinbusch, H. W. M., et al. (2015) · Scientific Reports · doi:10.1038/srep11138 · Cited by 71
Barrowman, J., Wang, W., Zhang, Y., & Ferro‐Novick, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302406200 · Cited by 67
Exchange and Redistribution Dynamics of the Cytoskeleton of the Active Zone Molecule Bassoon
Tsuriel, S., Fisher-Lavie, A., Wittenmayer, N., Dresbach, T., Garner, C. C., & Ziv, N. E. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4777-08.2009 · Cited by 66
Self-citationLoss of PCLO function underlies pontocerebellar hypoplasia type III
Ahmed, M. Y., Chioza, B. A., Rajab, A., Schmitz‐Abe, K., Al‐Khayat, A., Al-Turki, S., Baple, E. L., Patton, M. A., Al‐Memar, A., Hurles, M. E., et al. (2015) · Neurology · doi:10.1212/wnl.0000000000001523 · Cited by 66
Nishimune, H., Badawi, Y., Mori, S., & Shigemoto, K. (2016) · Scientific Reports · doi:10.1038/srep27935 · Cited by 68
Metadata
- Authors
- Fenster, S. D., Chung, W. J., Zhai, R., Cases-Langhoff, C., Voss, B., Garner, A. M., Kaempf, U., Kindler, S., Gundelfinger, E. D., & Garner, C. C.
- Affiliations
- University of Alabama at Birmingham (US)
- Universität Hamburg (DE)
- Leibniz Institute for Neurobiology (DE)
- Corresponding author
- Garner, Craig C
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2000-01
- Volume
- 25
- Issue
- 1
- Pages
- 203-214
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W1970539905
- Cited by
- 295
- References
- 49
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 4 · 2023: 11 · 2022: 9 · 2021: 8 · 2020: 7 · 2019: 9 · 2018: 7 · 2017: 14 · 2016: 13 · 2015: 16 · 2014: 11 · 2013: 11 · 2012: 14
- FWCI
- 7.89
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5p01ag006569-13, 5p50hd032901-05, 5r01ag012978-04)
- National Institute on Aging (AG 06569-09, AG12978-02)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (P50 HD32901)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- piccolo, bassoon, active zone, zinc finger proteins, synaptic vesicle trafficking, Rab3A, PRA1, glutamatergic synapses, GABAergic synapses, hippocampal neurons, neurotransmitter release
- MeSH terms
- Amino Acid Sequence, Animals, Base Sequence, Carrier Proteins, Cells, Cultured, Cytoskeletal Proteins, Exons, Fungal Proteins, gamma-Aminobutyric Acid, Hippocampus, Humans, Introns, Membrane Proteins, Molecular Sequence Data, Nerve Tissue Proteins, Neurons, Neuropeptides, Rabbits, Receptors, Cell Surface, Zinc Fingers, Presynaptic Terminals, Glutamic Acid, GTP-Binding Proteins, rab3A GTP-Binding Protein, Vesicular Transport Proteins, R-SNARE Proteins, Mice, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review