The DOI matches its Crossref record; 37 of the 42 references it cites were found in a registry or an index.
Single prediction equation for bioelectrical impedance analysis in adults aged 20–94 years
Abstract
Existing equations for bioelectrical impedance analysis (BIA) are of limited use when subjects age or become overweight because these equations were developed in young, normal-weight subjects and are not valid in elderly or overweight people. The purpose of this study was to validate a single BIA equation in healthy white subjects aged 22--94 y with a body mass index between 17.0 and 33.8 kg/m(2). Healthy subjects (202 men and 141 women) aged 20--94 y were measured by two methods: fat-free mass (FFM) was measured by dual-energy x-ray absorptiometry (Hologic QDR-4500) and by a bioelectrical impedance analyzer (Xitron 4000B). Validity of BIA was assessed by double cross validation. Because correlations were high (r = 0.986--0.987) and prediction errors low, a single equation was developed using all subjects, as follows: FFM = -4.104 + (0.518 x height(2)/resistance) + (0.231 x weight) + (0.130 x reactance) + (4.229 x sex: men = 1, women = 0). FFM predicted with dual-energy x-ray absorptiometry was 54.0 +/- 10.7 kg. BIA-predicted FFM was 54.0 +/- 10.5 kg (r = 0.986, standard error of the estimate = 1.72 kg, technical error = 1.74 kg). In conclusion, the new Geneva BIA equation was valid for prediction of FFM in healthy adults aged 22--94 y with body mass indexes between 17.0 and 33.8 kg/m(2). Inclusion of reactance in the single prediction equation appeared to be essential for use of BIA equations in populations with large variations in age or body mass.
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“The best BIA equations developed for specific population groups have been properly validated [22-24].”
Citations
Cites
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Lean body mass estimation by bioelectrical impedance analysis: a four-site cross-validation study
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Estimation of total body water by bioelectrical impedance analysis
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Sarcopenia: European consensus on definition and diagnosis
Cruz-Jentoft, A. J., Baeyens, J. P., Bauer, J. M., Boirie, Y., Cederholm, T., Landi, F., Martin, F. C., Michel, J.-P., Rolland, Y., Schneider, S. M., et al. (2010) · Age and Ageing · doi:10.1093/ageing/afq034 · Cited by 11,601
“Prediction equations have been validated for multiethnic adults [36] and reference values established for adult white men and women, including older subjects [37–39].”
BackgroundBioelectrical impedance analysis?part I: review of principles and methods
KYLE, U. (2004) · Clinical Nutrition · doi:10.1016/j.clnu.2004.06.004 · Cited by 3,200
Self-citationBioelectrical impedance analysis—part II: utilization in clinical practice
Kyle, U. G., Bosaeus, I., De Lorenzo, A. D., Deurenberg, P., Elia, M., Manuel Gómez, J., Lilienthal Heitmann, B., Kent-Smith, L., Melchior, J.-C., Pirlich, M., et al. (2004) · Clinical Nutrition · doi:10.1016/j.clnu.2004.09.012 · Cited by 2,350
“BIA has been shown to be valid with BMIs to 34 kg/m(2).(24,43) In morbid obesity, most predictive equations are unable to predict static body composition and are not reproducible for individuals over time.”
BackgroundSelf-citationQuantification of Lean Bodyweight
Janmahasatian, S., Duffull, S. B., Ash, S., Ward, L. C., Byrne, N. M., & Green, B. (2005) · Clinical Pharmacokinetics · doi:10.2165/00003088-200544100-00004 · Cited by 902
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“Several studies were conducted using the BIA method on children [68,105] adults [13], and elders [106,107].”
BackgroundMethodInfluential
Metadata
- Authors
- Kyle, U. G., Genton, L., Karsegard, L., Slosman, D. O., & Pichard, C.
- Affiliations
- University Hospital of Geneva (CH)
- Venue
- Nutrition
- Publisher
- Elsevier BV
- Published
- 2001-03
- Volume
- 17
- Issue
- 3
- Pages
- 248-253
- ISSN
- 0899-9007 (ISSN-L)
- OpenAlex
- W2041793073
- Cited by
- 575
- References
- 42
- Citations by year
- 2026: 13 · 2025: 19 · 2024: 26 · 2023: 24 · 2022: 28 · 2021: 39 · 2020: 27 · 2019: 31 · 2018: 34 · 2017: 35 · 2016: 32 · 2015: 35 · 2014: 35 · 2013: 26 · 2012: 33
- FWCI
- 7.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion)
- Funders
- Hôpitaux Universitaires de Genève
- Topics
- Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrical and Bioimpedance Tomography
- Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
- Keywords
- bioelectrical impedance analysis, fat-free mass, prediction equations, dual-energy X-ray absorptiometry, reactance, resistance, body mass index, older adults, overweight, validation, healthy adults
- MeSH terms
- Adult, Aged, Aged, 80 and over, Aging, Body Composition, Female, Humans, Male, Middle Aged, Reference Values, Regression Analysis, Reproducibility of Results, Absorptiometry, Photon, Body Mass Index, Electric Impedance
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