Estimation of total body water by bioelectrical impedance analysis
Abstract
Total body water (TBW) measured by bioelectrical impedance analysis (BIA) was directly compared with deuterium-isotope dilution in a total of 58 subjects. First, sex-specific and group equations were developed by multiple regression analysis in (10 each) obese and nonobese men and women. Height/resistive impedance was the most significant variable used to predict deuterium-dilution space (D2O-TBW) and, combined with weight, yielded R = 0.99 and SE of estimate = 1.75 L. Equations predicted D2O-TBW equally well for obese and nonobese subjects. Second, the equations were prospectively tested in a heterogeneous group of 6 males and 12 females. Sex-specific equations predicted D2O-TBW with good correlation coefficients (0.96 and 0.93), total error (2.34 and 2.89 L), and a small difference between mean predicted and measured D2O-TBW (-1.4 +/- 2.05 and -0.48 +/- 2.83 L). BIA predicts D2O-TBW more accurately than weight, height, and/or age. A larger population is required to validate the applicability of our equations.
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The study tested its equations against earlier published BIA equations whose development samples Dioum et al. assumed included at least some black participants.
“Performance of developed equations for the prediction of FFM was also tested using all available data (n=362) against previously published equations derived using participant samples which were assumed by Dioum et al. to consist of at least some ethnically black participants (5, 24–32).”
From Prediction of fat-free mass using bioelectrical impedance analysis in young adults from five populations of African origin (2013) · cites this paper as [25]
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- Authors
- Kushner, R., & Schoeller, D.
- Affiliations
- University of Chicago (US)
- Corresponding author
- Kushner, RF
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1986-09
- Volume
- 44
- Issue
- 3
- Pages
- 417-424
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W2165894511
- Cited by
- 772
- References
- 12
- Citations by year
- 2026: 7 · 2025: 25 · 2024: 10 · 2023: 7 · 2022: 16 · 2021: 19 · 2020: 6 · 2019: 16 · 2018: 9 · 2017: 15 · 2016: 19 · 2015: 20 · 2014: 20 · 2013: 21 · 2012: 22
- FWCI
- 9.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (2p30am026678-06)
- Topics
- Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrical and Bioimpedance Tomography
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- total body water, bioelectrical impedance analysis, prediction equations, obesity, resistive impedance, body composition
- MeSH terms
- Adolescent, Adult, Aged, Body Composition, Body Water, Deuterium, Electrochemistry, Female, Humans, Indicator Dilution Techniques, Male, Middle Aged, Regression Analysis, Sex Factors
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