The DOI matches its Crossref record; 14 of the 16 references it cites were found in a registry or an index.
Comparative expression of the mouse Sox1, Sox2 and Sox3 genes from pre-gastrulation to early somite stages
Open accessAbstract
Whole mount in situ hybridisation was used to study the embryonic expression of the mouse HMG box-containing genes Sox1, Sox2 and Sox3 between 6.5 and 9.0 days post coitum (dpc). Sox2 and Sox3 are expressed in the epiblast and extraembryonic ectoderm of the egg cylinder, becoming restricted to the prospective neural plate and chorion at the onset of gastrulation. Sox3 is upregulated in the posterior ectoderm during late streak and neural plate stages and is concomitantly downregulated in the chorion. Sox1 transcripts are first detected in the neural fold ectoderm at the headfold stage. During early somitogenesis, all three genes are expressed in the neuroectoderm, and Sox2 and Sox3 are also expressed in the primitive streak ectoderm, gut endoderm and prospective sensory placodes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Similarly, Sox2 is expressed in both ectoderm and endoderm libraries corresponding to published expression patterns [38].”
From A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE) (2007) · cites this paper as [38]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
In situ hybridization; a practical approach
(1993) · International Journal of Biochemistry · doi:10.1016/0020-711x(93)90093-t · Cited by 1,240
Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope
Downs, K. M., & Davies, T. J. (1993) · Development · doi:10.1242/dev.118.4.1255 · Cited by 582
A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2
Collignon, J., Sockanathan, S., Hacker, A., Cohen‐Tannoudji, M., Norris, D. P., Rastan, S., Stevanović, M. J., Goodfellow, P. N., & Lovell-Badge, R. H. (1996) · Development · doi:10.1242/dev.122.2.509 · Cited by 496
Pevny, L., & Lovell-Badge, R. H. (1997) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(97)80147-5 · Cited by 489
A role for SOX1 in neural determination
Pevny, L., Sockanathan, S., Placzek, M., & Lovell-Badge, R. H. (1998) · Development · doi:10.1242/dev.125.10.1967 · Cited by 475
Uwanogho, D., Rex, M., Cartwright, E. J., Pearl, G., Healy, C., Scotting, P. J., & Sharpe, P. T. (1995) · Mechanisms of Development · doi:10.1016/0925-4773(94)00299-3 · Cited by 391
Sox1 directly regulates the gamma -crystallin genes and is essential for lens development in micePreprint
Nishiguchi, S., Wood, H. B., Kondoh, H., Lovell-Badge, R. H., & Episkopou, V. (1998) · Genes & Development · doi:10.1101/gad.12.6.776 · Cited by 290
Self-citationClonal Analysis of Cell Fate During Gastrulation and Early Neurulation in the Mouse
Lawson, K. A., & Pedersen, R. A. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514221.ch2 · Cited by 177
Preventing the loss of competence for neural induction: HGF/SF, L5 and Sox-2
Streit, A., Sockanathan, S., Pérez, L., Rex, M., Scotting, P. J., Sharpe, P. T., Lovell-Badge, R. H., & Stern, C. D. (1997) · Development · doi:10.1242/dev.124.6.1191 · Cited by 159
Establishment and Organization of Germ Layers in the Gastrulating Mouse Embryo
Tam, P., & Beddington, R. S. P. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514221.ch3 · Cited by 152
Cited by
Sorted by citations
Items 401–500 of 555
Embryonic stem cells as a cell source for treating Parkinson’s disease
Fukuda, H., & Takahashi, J. B. (2005) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.5.10.1273 · Cited by 10
“Sox1 is the earliest known specific marker of neuroectoderm in the mouse embryo [48].”
BackgroundSoxB, cell cycle and neurogenesis
Karnavas, T., Mandalos, N. P., Malas, S., & Remboutsika, E. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00298 · Cited by 10
“During CNS development, dividing NEPs, residing in the ventricular zone (VZ), either self-renew or exit the cell cycle and differentiate.”
BackgroundInfluentialDbx1 Is a Direct Target of SOX3 in the Spinal Cord
Rogers, N., McAninch, D., & Thomas, P. Q. (2014) · PLoS ONE · doi:10.1371/journal.pone.0095356 · Cited by 10
“This is likely due to the expression of Sox1 and Sox2 in N2B27-induced NP cells and is consistent with the mild CNS phenotype of Sox3 null embryos.”
BackgroundInfluentialLi, M., Zou, Y. S., Lu, Q., Tang, N., Heng, A., Islam, I., Tong, H. J., Dawe, G. S., & Cao, T. (2016) · Journal of Biomedical Science · doi:10.1186/s12929-016-0251-6 · Cited by 10
“Specifically, cells occupying the lateral regions of the FP express SOX1, whereas cells occupying the medial region do not [10, 11].”
BackgroundHan, D., Xu, W., Jeong, H., Park, H., Weyer, K., Tsytsyura, Y., Stehling, M., Wu, G., Lan, G., Kim, K.-P., et al. (2025) · Nature Cell Biology · doi:10.1038/s41556-025-01641-w · Cited by 9
“Furthermore, pNSCs could be derived only from Sox1 + cells, which is the earliest known NSC-specific marker 29,30 .”
Lanctôt, C. (2015) · Stem Cells · doi:10.1002/stem.2108 · Cited by 10
Long-term self-renewal of naïve neural stem cells in a defined condition
Wu, Y., Chen, X. X., Xi, G., Zhou, X., Pan, S., & Ying, Q. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2019.03.001 · Cited by 10
Arima, N., Uchida, Y., Yu, R., Nakayama, K., & Nishina, H. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.05.006 · Cited by 9
The release of single cells from embryoid bodies in a capillary flow device
Papantoniou, I., Hoare, M., & Veraitch, F. S. (2010) · Chemical Engineering Science · doi:10.1016/j.ces.2010.10.026 · Cited by 9
Serial Analysis of Gene Expression in the Chicken Otocyst
Sinkkonen, S. T., Starlinger, V., Galaiya, D. J., Laske, R. D., Myllykangas, S., Oshima, K., & Heller, S. (2011) · Journal of the Association for Research in Otolaryngology · doi:10.1007/s10162-011-0286-z · Cited by 9
“For example, known and easily detectable otocyst genes such as SOX2, PAX8, and FOXI3 (Groves and BronnerFraser 2000; Ohyama and Groves 2004; Uchikawa et al. 1999; Wood and Episkopou 1999) were not represented in our library, and 45% of all annotated tags were only represented once.”
A New 6-bp SOX-3 Polyalanine Tract Deletion Does Not Segregate with Mental Retardation
Salemi, M., Romano, C., Ragusa, L., Vita, G. D., Salluzzo, R., Oteri, I., Trovato, M. L., Romano, C., Caraci, F., Nicoletti, F., et al. (2007) · Genetic Testing · doi:10.1089/gte.2006.0510 · Cited by 9
“…of the SOX-B1 subfamily are coexpressed throughout the developing central nervous system (CNS) (Collignon et al ., 1996; Uchikawa et al ., 1999; Wood and Episkopou, 1999) and can be involved in many different processes, including maintenance of pluripotency in self-renewing stem cells,…”
Yoon, S. H., Bae, M.-R., La, H., Song, H., Hong, K., & Tae, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158322 · Cited by 8
Zhao, R., Moore, E. L., Gogol, M., Unruh, J. R., Yu, Z., Scott, A. R., Wang, Y., Rajendran, N. K., & Trainor, P. A. (2024) · eLife · doi:10.7554/elife.92844 · Cited by 21
Schock, E. N., York, J. R., Li, A. P., Tu, A. Y., & LaBonne, C. (2024) · Development · doi:10.1242/dev.202693 · Cited by 7
Craniofacial Development Is Fine-Tuned by Sox2
Mandalos, N. P., Dimou, A., Gavala, M. A., Lambraki, E., & Remboutsika, E. (2023) · Genes · doi:10.3390/genes14020380 · Cited by 7
Baizabal, J., Valencia, C., Guerrero-Flores, G., & Covarrubias, L. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2010.11.003 · Cited by 7
Incitti, T., Messina, A., Bozzi, Y., & Casarosa, S. (2014) · BioResearch open access · doi:10.1089/biores.2014.0009 · Cited by 7
“This finding is in line with what previously known about temporal expression of early neural markers 24,26 and was also confirmed by Western blot and ICC analyses (Fig.”
Ground-State Transcriptional Requirements for Skin-Derived Precursors
Suflita, M. T., Pfaltzgraff, E. R., Mundell, N. A., Pevny, L., & Labosky, P. A. (2013) · Stem Cells and Development · doi:10.1089/scd.2012.0501 · Cited by 7
“Neural crest cells (NCCs) are a highly multipotent cell type with broad differentiation potential.”
BackgroundInfluentialSears, K. E., Gullapalli, K., Trivedi, D., Mihas, A. K., Bukys, M. A., & Jensen, J. N. (2022) · iScience · doi:10.1016/j.isci.2022.104133 · Cited by 6
“In fact, general neural markers Pax6 and Sox1 are not detected in developing neuroectoderm until after the onset of somitogenesis, when A/P-patterning has already been established (Callaerts et al., 1997; Wood and Episkopou, 1999).”
BackgroundLi, F., Zhang, A., Li, M., Wang, X., Wang, X., Guan, Y., An, J., Han, D., Zhang, Y. A., & Chen, Z. (2022) · Acta Histochemica · doi:10.1016/j.acthis.2022.151927 · Cited by 6
Heads or tails: making the spinal cord
Needham, J., & Metzis, V. (2022) · Developmental Biology · doi:10.1016/j.ydbio.2022.03.002 · Cited by 6
Conversion of rat embryonic stem cells into neural precursors in chemical-defined medium
Peng, X., Gao, H., Wang, Y., Yang, B., Liu, T., Sun, Y., Jin, H., Jiang, L., Li, L., Wu, M., et al. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.01.023 · Cited by 6
How are pluripotent cells captured in culture?
Kinoshita, M. (2014) · Reproductive Medicine and Biology · doi:10.1007/s12522-014-0199-8 · Cited by 6
“cell lineage in addition to epiblast [79].”
SOX2 in Neurosensory Fate Determination and Differentiation in the Inner Ear
Cheah, K. S. E., & Xu, P. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800352-7.00015-3 · Cited by 6
Taboada, X., Viñas, A. M., & Adrio, F. (2017) · The Journal of Comparative Neurology · doi:10.1002/cne.24374 · Cited by 6
“…expression patterns could reveal the degree of redundancy in their functions, as it was reported for Sox1, Sox2, and Sox3 in the CNS of other vertebrates (Graham, Khudyakov, Ellis, & Pevny, 2003; Pevny & Placzek, 2005; Sarkar & Hochedlinger, 2013; Uwanogho et al., 1995; Wood & Episkopou, 1999).”
BackgroundChanda, S., Sahoo, S., & Sahni, S. (2021) · Linguistics and Culture Review · doi:10.21744/lingcure.v5ns3.1843 · Cited by 6
SOX2-Dependent Regulation of Pluripotent Stem Cells
Wong, F. C. K., Chambers, I., & Mullin, N. P. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800352-7.00010-4 · Cited by 6
Comparison of promoter regions ofSOX3,SOX14andSOX18orthologs in mammals
Kovačević‐Grujičić, N., Kovačević‐Grujičić, N., Mojsin, M. M., Kovačević‐Grujičić, N., Mojsin, M. M., Djurovic, J., Kovačević‐Grujičić, N., Mojsin, M. M., Djurovic, J., Petrović, I., et al. (2008) · DNA sequence · doi:10.1080/10425170701462092 · Cited by 6
“In the mouse embryo, Sox3 is expressed in the primitive ectoderm, epiblast and neuroepithelium (Collignon et al. 1996; Wood and Episkopou 1999) and Wang et al. (2006) showed that Sox3 protein expression persists in the neonatal and adult mouse forebrain.”
BackgroundGalichet, C., Rizzoti, K., & Lovell-Badge, R. H. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011395 · Cited by 5
Epigenetics and chromatin plasticity in embryonic stem cells
Přikrylová, T. (2013) · World Journal of Stem Cells · doi:10.4252/wjsc.v5.i3.73 · Cited by 7
Takata, N., Sakakura, E., & Sasai, Y. (2016) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-016-0012-6 · Cited by 5
Multiple Roles for SOX2 in Eye Development
Kondoh, H., Uchikawa, M., & Ishíi, Y. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800352-7.00012-8 · Cited by 5
Generation of a biotinylatable Sox2 mouse model to identify Sox2 complexes in vivo
Schilders, K. A. A., Eenjes, E., Edel, G. G., Munck, A. B., Kempen, M. B., Demmers, J., Wijnen, R. M. H., Tibboel, D., & Rottier, R. J. (2018) · Transgenic Research · doi:10.1007/s11248-018-0058-1 · Cited by 5
“Early during development, expression of Sox2 is restricted to the anterior ectoderm, from which the neuroectoderm and anterior surface ectoderm will arise (Papanayotou et al. 2008; Wood and Episkopou 1999).”
Pluripotent Stem Cells as an In Vitro Model of Neuronal Differentiation
Kerkis, I., Hayashi, M. A. F., Nelson, F., Antonio, C., Lygia, V., & Kerkis, A. (2011) · InTech eBooks · doi:10.5772/24695 · Cited by 5
Generation of brain organoids from mouse ESCs via teratoma formation
Lee, W. J., Lee, J. E., Hong, Y. J., Yoon, S. H., Song, H., Park, C., Hong, K., Choi, Y., & Tae, J. (2020) · Stem Cell Research · doi:10.1016/j.scr.2020.102100 · Cited by 6
Zhao, R., Moore, E. L., Gogol, M., Unruh, J. R., Yu, Z., Scott, A. R., Wang, Y., Rajendran, N. K., & Trainor, P. A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.26.564204 · Cited by 5
NANOG is repurposed after implantation to repress Sox2 and begin pluripotency extinction
Wong, F. C. K., Zhang, M., Thomson, E., Schumacher, L. J., Tsakiridis, A., Ashmore, J., Li, T., Blin, G., Karagianni, E., Mullin, N. P., et al. (2025) · The EMBO Journal · doi:10.1038/s44318-025-00527-9 · Cited by 6
“Intriguingly, however, spatially restricted expression patterns of these core components have been reported (Hoffman et al, 2013; Osorno et al, 2012; Sumi et al, 2013; Sun et al, 2014; Wood and Episkopou, 1999).”
Gao, X., Tian, H., Liu, L., Yu, M., Jing, N., & Zhao, F.-K. (2009) · Journal of Proteome Research · doi:10.1021/pr800889p · Cited by 4
Ernsberger, U. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-2049-8 · Cited by 5
Kovačević‐Grujičić, N., Mojsin, M. M., Popovic, J., Petrović, I., Topalović, V., & Stevanović, M. J. (2014) · BMB Reports · doi:10.5483/bmbrep.2014.47.4.084 · Cited by 4
Zhao, R., Moore, E. L., Gogol, M., Unruh, J. R., Yu, Z., Scott, A. R., Wang, Y., Rajendran, N. K., & Trainor, P. A. (2024) · eLife · doi:10.7554/elife.92844.2 · Cited by 4
Genome-wide DNA-binding profile of SRY-box transcription factor 3 (SOX3) in mouse testes
McAninch, D., Thomson, E., & Thomas, P. Q. (2020) · Reproduction Fertility and Development · doi:10.1071/rd20108 · Cited by 3
Applying Spinal Cord Organoids as a quantitative approach to study the mammalian Hedgehog pathway
Holzner, M., Wutz, A., & Minin, G. D. (2024) · PLoS ONE · doi:10.1371/journal.pone.0301670 · Cited by 3
Tsuruoka, M., Tokizaki, H., & Yamasu, K. (2025) · Cells and Development · doi:10.1016/j.cdev.2025.204026 · Cited by 3
Trans-activation of the human SOX3 promoter by MAZ in NT2/D1 cells
Kovačević‐Grujičić, N., Yokoyama, K. K., & Stevanović, M. J. (2008) · Archives of Biological Sciences · doi:10.2298/abs0803379k · Cited by 3
Cell biology of fetal tissues and fundamental medicine
Repin, V. S., Saburina, I. N., & Sukhikh, G. T. (2007) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-007-0268-7 · Cited by 3
Lin−CD34− bone marrow cells from adult mice can differentiate into neural-like cells
Li, Q., Hosaka, N., Cui, W., Wang, X., Cui, Y., Cui, Y., Song, C., Li, Q., Ryu, T., Fan, T., et al. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.08.063 · Cited by 3
Kondoh, H., & Lovell-Badge, R. H. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800352-7.00001-3 · Cited by 3
Epigenetic Signature of Embryonal Stem Cells: A DNA Methylation Perspective
Abu-Remaileh, M., & Bergman, Y. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-227-8_20 · Cited by 3
“ectoderm, anterior primitive ectoderm, germ cells, and multipotent extra embryonic ectoderm cells [36, 37].”
BackgroundStem Cells in Reproduction and in the Brain
Morser, J., Schöler, H. R., & Nishikawa, S. I. (2006) · Springer eBooks · doi:10.1007/3-540-31437-7 · Cited by 3
Two parallel lineage-committed progenitors contribute to the developing brainPreprint
Dundes, C. E., Jokhai, R. T., Ahsan, H. S., Kang, R. S., Salomon, R. E. A., Rajan, A., Kim, Y. S., Stanton, L. J., Xu, C. L., Do, S., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.02.662771 · Cited by 3
SOX Genes in Spinal Cord Injury: Redefining Neural Stem Cell Regeneration Strategies
Dhar, A., Moinuddin, F. M., Zamanian, C., Sharar, A. D., Dominari, A., Graepel, S. P., Windebank, A. J., & Bydon, M. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04882-w · Cited by 2
“For example, in the mouse epiblast, both Sox2 and Sox3 are expressed, whereas in the chicken embryo, only Sox3 is present before gastrulation [80–82].”
A Rapid Way to Map Outheld-Wing Mutation in Drosophila melanogaster
Yu, B., Cao, H., Zhao, C., Wu, C., & Deng, X. (2011) · Asian Journal of Animal and Veterinary Advances · doi:10.3923/ajava.2011.242.254 · Cited by 2
Functional characterization of the Japanese flounder (Paralichthys olivaceus) Sox2 gene promoter
Liu, W., Song, H., Li, A., Du, X., Liu, Y., He, Y., Zhang, Q., & Qi, J. (2016) · Fish Physiology and Biochemistry · doi:10.1007/s10695-016-0216-4 · Cited by 2
Ectopic expression of T in the paraxial mesoderm disrupts somite maturation in the mouse
Campbell, G. P., Farkas, D. R., & Chapman, D. L. (2022) · Developmental Biology · doi:10.1016/j.ydbio.2022.02.010 · Cited by 2
Conservation of cis-Regulatory Syntax Underlying Deuterostome Gastrulation
Buono, L., Annona, G., Magri, M. S., Negueruela, S., Sepe, R. M., Caccavale, F., Maeso, I., Arnone, M. I., & D’Aniello, S. (2024) · Cells · doi:10.3390/cells13131121 · Cited by 2
Ohyanagi, T., Tokizaki, H., Sato, T., Tsuruoka, M., & Yamasu, K. (2025) · genesis · doi:10.1002/dvg.70015 · Cited by 2
The Role of SOX2 in Maintaining Pluripotency and Differentiation of Human Embryonic Stem Cells
Adachi, K., Suemori, H., Nakatsuji, N., & Kawase, E. (2011) · InTech eBooks · doi:10.5772/23094 · Cited by 2
“By contrast, Sox2 is widely expressed during embryonic development and occurs not only in the inner cell mass and epiblast but also in neural tissues, extra embryonic ectoderm, gut endoderm, esophagus and trachea (Avilion et al., 2003; Williamson et al., 2006; Wood and Episkopou, 1999).”
BackgroundGene Expression in Embryonic Neural Development and Stem Cell Differentiation
Yan, C. Y. I., Felipe, M. D. A. A., Yanes, T., Turri, J. A. O., & Hayashi, M. A. F. (2012) · InTech eBooks · doi:10.5772/38067 · Cited by 2
“For instance, the early neural marker Sox3 and late marker Sox2 have been used as standard indicators of neural bias and specification (Fernandez-Garre et al., 2002; Rex et al., 1997; Streit et al., 2000, 1997; Uchikawa, 2003; Wood & Episkopou, 1999).”
MethodModeling to Optimize Terminal Stem Cell Differentiation
Gallicano, G. I. (2013) · Scientifica · doi:10.1155/2013/574354 · Cited by 2
Epigenetic Reprogramming Induced Pluripotency
Meiliana, A., & Wijaya, A. (2011) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v3i2.139 · Cited by 2
Induced Pluripotent Stem Cells Generated from P0-Cre;Z/EG Transgenic Mice
Ogawa, Y., Eto, A., Miyake, C., 土田奈々枝, Miyake, H., Takaku, Y., Hagiwara, H., & Oishi, K. (2015) · PLoS ONE · doi:10.1371/journal.pone.0138620 · Cited by 2
“Sox1 is the earliest known specific marker of neuroectoderm in the mouse embryo [37], which is expressed in the neural plate of mouse embryos at E7.”
BackgroundA complex structural variant near SOX3 causes X-linked split-hand/foot malformation
de Boer, E., Marcelis, C., Neveling, K., van Beusekom, E., Hoischen, A., Klein, W. M., de Leeuw, N., Mantere, T., Melo, U. S., van Reeuwijk, J., et al. (2023) · Human Genetics and Genomics Advances · doi:10.1016/j.xhgg.2023.100200 · Cited by 2
Takemoto, T. (2014) · Springer eBooks · doi:10.1007/978-4-431-54634-4_7 · Cited by 2
Converting ES Cell into Neurons
Smith, A. G. (2004) · Research and perspectives in neurosciences · doi:10.1007/978-3-642-18883-1_6 · Cited by 2
Data describing Rax positive optic-vesicle generation from mouse embryonic stem cells in vitro
Takata, N., Eiraku, M., & Sakakura, E. (2016) · Data in Brief · doi:10.1016/j.dib.2016.05.070 · Cited by 2
Disorders of Hypothalamo‐Pituitary Axis
Gan, H., Alatzoglou, K. S., & Dattani, M. (2019) · Wiley eBooks · doi:10.1002/9781119152712.ch5 · Cited by 2
Zhao, R., Moore, E. L., Gogol, M., Uhruh, J., Yu, Z., Scott, A. R., Wang, Y., Rajendran, N. K., & Trainor, P. A. (2024) · eLife · doi:10.7554/elife.92844.1 · Cited by 2
Chemically induced cell plasticity enables the generation of high-fidelity embryo modelPreprint
Li, H., Huang, J., Guan, W., Wu, J., Luo, H., Chang, L., Zhao, H., Chen, C., Gao, Y., Zhang, J., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.20.598030 · Cited by 2
Bryant, P. J., & Schwartz, P. H. (2019) · University of California Press eBooks · doi:10.1525/9780520940994-002 · Cited by 1
Bağcı, F. Ö., Özgörgülü, A., Çiçek, G., Özen, E. U., Duman, S., Aktan, T. M., & Reisli, İ. (2025) · Cureus · doi:10.7759/cureus.83115 · Cited by 1
Diverse SOX3 genetic variants and their associated phenotypic spectrum in human disease
Dominicis, C. D., Birtolo, M. F., Lania, A. G., & Trivellin, G. (2026) · Endocrine Reviews · doi:10.1210/endrev/bnag008 · Cited by 1
Two parallel neural ectoderm progenitors contribute to the developing brain
Jokhai, R. T., Dundes, C. E., Ahsan, H. S., Kang, R. S., Salomon, R. E. A., Rajan, A., Kim, Y. S., Stanton, L. J., Xu, C. L., Do, S., et al. (2026) · Nature Neuroscience · doi:10.1038/s41593-026-02433-7 · Cited by 5
Structural Abnormalities in Congenital Growth Hormone Deficiency
Secco, A., Iorgi, N. D., & Maghnie, M. (2011) · Humana Press eBooks · doi:10.1007/978-1-60761-317-6_6 · Cited by 1
Embryonic Stem Cells and Neurogenesis
Wesselschmidt, R. L. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3801-4_2 · Cited by 1
Role of SOX2 in foregut development in relation to congenital abnormalities
Schilders, K. A. A. (2014) · World Journal of Medical Genetics · doi:10.5496/wjmg.v4.i4.94 · Cited by 1
Anophthalmia, Colobomatous, Microphthalmia, and Optic Fissure Closure Defects
Brooks, B. P., & Traboulsi, E. I. (2012) · doi:10.1093/med/9780195326147.003.0005 · Cited by 1
Anophthalmia, Microphthalmia, and Uveal Coloboma
Brooks, B. P. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-383834-6.00181-6 · Cited by 1
Role of SOX2 in the Hypothalamo–Pituitary Axis
Rizzoti, K., & Lovell-Badge, R. H. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800352-7.00014-1 · Cited by 1
Isolation of Stem Cells from Multiple Sites in the CNS
Rao, M. S., & Pevny, L. (2003) · Springer eBooks · doi:10.1007/0-306-48356-4_4 · Cited by 1
Takata, N., Sakakura, E., Sakuma, T., & Yamamoto, T. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-7108-4_19 · Cited by 1
Uchikawa, M., & Takemoto, T. (2009) · Springer eBooks · doi:10.1007/978-4-431-09427-2_7 · Cited by 1
A revised staging of mouse development before organogenesis
Lawson, K. A., & Wilson, V. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-23739-3.00009-2 · Cited by 1
Glycans in Embryonic Stem Cells
Pickford, C. E., Holley, R. J., Meade, K. A., & Merry, C. L. R. (2011) · Springer eBooks · doi:10.1007/978-3-642-16833-8_5 · Cited by 1
“Sox1 is the earliest known specific marker of neuroectodermal precursor cells (Wood and Episkopou 1999) and has a highly restricted pattern of expression – it is expressed in the neural plate and neuroepithelial cells but down-regulated during neuronal and glial differentiation.”
BackgroundDiagnostic Immunopathology of Germ Cell Tumors
Preda, O., & Nogales, F. F. (2017) · Springer eBooks · doi:10.1007/978-3-662-53775-6_4 · Cited by 1
Regulation der Entwicklung der Hypophyse
Pfäffle, R. W., Weigel, J. F. W., & Böttner, A. (2006) · Springer eBooks · doi:10.1007/3-540-28782-5_4 · Cited by 1
Congenital Disorders of the Hypothalamo‐Pituitary‐Somatotrope Axis
Mehta, A., Gevers, E. F., & Dattani, M. (2009) · Wiley eBooks · doi:10.1002/9781444316728.ch4 · Cited by 1
Development and appraisal of MRI contrast agents for the in vivo analysis of stem cell grafts
Williams, S. (2012) · ORCA Online Research @Cardiff (Cardiff University) · Cited by 1
Tcf4 is a target gene of the imprinted gene Zac1 during mouse neurogenesis
Daniel, G. (2012) · doi:10.5282/edoc.15766 · Cited by 1
Generation of midbrain dopaminergic neurons in vivo and in vitro: the role of Neurogenin2
Andersson, E. (2005) · Lund University Publications (Lund University) · Cited by 1
Mutations Involving RBP4 and SOX3 Underlie Two Novel Forms of Congenital Eye Malformations.
Chou, C. M. (2012) · Deep Blue (University of Michigan) · Cited by 1
SERF deletion modifies amyloid aggregation in a mouse model of Alzheimer’s diseasePreprint
Stroo, E., Janssen, L., Sin, O., Hogewerf, W., Koster, M. H., Harkema, L., Youssef, S. A., Beschörner, N., Wolters, A. H. G., Bakker, B., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.05.423442 · Cited by 1
Isolation and characterisation of chick embryonic primordial germ cells
Intarapat, S. (2012) · UCL Discovery (University College London)
Identification and Maintenance of Neural Precursors from Human Embryonic Stem Cells
Reubinoff, B. E., & Khaner, H. (2004) · Elsevier eBooks · doi:10.1016/b978-012436643-5/50058-4
Regulation of neurogenesis in the vertebrate CNS
Källström, M. (2008) · Figshare
Taupin, P. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-021-8_2
Mammalian Neural Stem Cell Renewal
Arsenijévic, Y. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-021-8_11
Mammalian Inner Ear Development: Of Mice and Man
Fritzsch, B., & Beisel, K. W. (2005) · Wiley eBooks · doi:10.1002/9783527619689.ch14
Sandberg, M. (2010)
Metadata
- Authors
- Wood, H. B., & Episkopou, V.
- Affiliations
- Hammersmith Hospital (GB)
- Corresponding author
- Episkopou, Vasso
- Venue
- Mechanisms of Development
- Publisher
- Elsevier BV
- Published
- 1999-08
- Volume
- 86
- Issue
- 1-2
- Pages
- 197-201
- ISSN
- 0925-4773 (ISSN-L)
- OpenAlex
- W2055664397
- Cited by
- 550
- References
- 16
- Citations by year
- 2026: 7 · 2025: 10 · 2024: 15 · 2023: 5 · 2022: 17 · 2021: 16 · 2020: 11 · 2019: 15 · 2018: 18 · 2017: 23 · 2016: 14 · 2015: 31 · 2014: 29 · 2013: 24 · 2012: 30
- FWCI
- 2.61
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Mechanisms of Development (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Medical Research Council
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Pluripotent Stem Cells Research
- Keywords
- SOX1, SOX2, SOX3, gene expression, mouse embryo, gastrulation, neural plate, neural fold, somitogenesis, primitive streak, chorion, extraembryonic ectoderm, neuroectoderm
- MeSH terms
- Animals, Central Nervous System, DNA-Binding Proteins, Ectoderm, Embryo, Mammalian, Gastrula, High Mobility Group Proteins, Nuclear Proteins, Rhombencephalon, Transcription Factors, Gene Expression Regulation, Developmental, HMGB Proteins, Mice, SOXB1 Transcription Factors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
