Cited by 374Neuroscience and Neuropharmacology ResearchCell Adhesion Molecules ResearchGenetics and Neurodevelopmental Disorders

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Synaptic adhesion molecules

Yamagata, Masahito, Sanes, Joshua R, Weiner, Joshua A·2003·Current Opinion in Cell Biology

DOI 10.1016/s0955-0674(03)00107-8

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Abstract

Formation, differentiation and plasticity of synapses, the specialized cell-cell contacts through which neurons communicate, all require interactions between pre- and post-synaptic partners. Several synaptically localized adhesion molecules potentially capable of mediating these interactions have been identified recently. Functional studies suggest roles for some of them in target recognition (e.g. SYG-1 and sidekicks), formation and alignment of synaptic specializations (e.g. SynCAM, neuroligin and neurexin), and regulation of synaptic structure and function (e.g. cadherins and syndecan).

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Authors: Yamagata, M., Sanes, J. R., & Weiner, J. A.
Affiliations: Washington University in St. Louis (US)
Corresponding author: Yamagata, Masahito
Sanes, Joshua R
Weiner, Joshua A
ORCID: Yamagata, Masahito
Sanes, Joshua R
Weiner, Joshua A
Venue: Current Opinion in Cell Biology
Publisher: Elsevier BV
Published: 2003-10
Volume: 15
Issue: 5
Pages: 621-632
ISSN: 0955-0674 (ISSN-L)
DOI: 10.1016/s0955-0674(03)00107-8
OpenAlex: W2067561211
Cited by: 374
References: 98
Citations by year: 2026: 12 · 2025: 10 · 2024: 4 · 2023: 9 · 2022: 7 · 2021: 4 · 2020: 17 · 2019: 12 · 2018: 8 · 2017: 6 · 2016: 16 · 2015: 12 · 2014: 13 · 2013: 17 · 2012: 11
FWCI: 2.64
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: Current Opinion in Cell Biology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Health Sciences › Medicine › Immunology and Allergy › Cell Adhesion Molecules Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Keywords: synaptic adhesion molecules, synaptogenesis, synaptic plasticity, target recognition, side kick, neuroligins, neurexin, cadherins, syndecans, synaptic specializations
MeSH terms: Amino Acid Sequence, Animals, Axons, Cytoskeleton, Immunoglobulins, Nerve Tissue Proteins, Synaptic Transmission, Synapses, Synaptic Vesicles, Cell Adhesion Molecules, Cadherins, Protein Structure, Tertiary, Neural Cell Adhesion Molecules, GTP-Binding Proteins, Caenorhabditis elegans Proteins

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