The DOI matches its Crossref record; 43 of the 46 references it cites were found in a registry or an index.
The nature of the last universal common ancestor
Abstract
Cytologically, prokaryotes appear simpler and thus evolutionarily 'older' than eukaryotes. In terms of RNA processing, however, prokaryotes are sophisticated and eukaryotes, which retain many features of an RNA-world, appear primitive. The last universal common ancestor may have been mesophilic and could have had many features of the eukaryote genome, but its cytology is unknown.
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“This LUCA—the last universal common ancestor of all organisms (Penny and Poole, 1999; Delaye et al., 2005)—was most likely a population of cells resulting from previous prebiotic, and earliest biological, evolution and selection.”
From The Astrobiology Primer v2.0 (2016) · cites this paper as Penny and Poole, 1999
Citations
Cites
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Martin, W., & Russell, M. J. (2003) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2002.1183 · Cited by 856
On the origin of genomes and cells within inorganic compartments
Koonin, E. V., & Martin, W. (2005) · Trends in Genetics · doi:10.1016/j.tig.2005.09.006 · Cited by 406
(2006) · Genome biology · doi:10.1186/gb-2006-7-10-118 · Cited by 355
Ancient Phylogenetic Relationships
Gribaldo, S., & Philippe, H. (2002) · Theoretical Population Biology · doi:10.1006/tpbi.2002.1593 · Cited by 314
Forterre, P. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510333103 · Cited by 242
Metadata
- Authors
- Penny, D., & Poole, A.
- Affiliations
- Massey University (NZ)
- Stockholm University (SE)
- Corresponding author
- Penny, David
- Poole, Anthony
- ORCID
- Poole, Anthony
- Venue
- Current Opinion in Genetics & Development
- Publisher
- Elsevier BV
- Published
- 1999-12
- Volume
- 9
- Issue
- 6
- Pages
- 672-677
- ISSN
- 0959-437X (ISSN-L)
- OpenAlex
- W1963854145
- Cited by
- 162
- References
- 46
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 5 · 2023: 4 · 2022: 1 · 2021: 2 · 2020: 5 · 2019: 5 · 2018: 9 · 2017: 5 · 2016: 5 · 2015: 6 · 2014: 9 · 2013: 5 · 2012: 4
- FWCI
- 0.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Genetics & Development (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Protist diversity and phylogeny
- Keywords
- last universal common ancestor, prokaryotes, eukaryotes, RNA processing, RNA world, eukaryotic genome evolution, eukaryotic origin
- MeSH terms
- Animals, Eukaryotic Cells, Genes, Models, Genetic, Phylogeny, Prokaryotic Cells, RNA, Selection, Genetic, Temperature, Genome, Evolution, Molecular
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