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Dynamin 3 Is a Component of the Postsynapse, Where it Interacts with mGluR5 and Homer

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Gray, Noah W., Fourgeaud, Lawrence, Huang, Bing, Chen, Jing, Cao, Hong, Oswald, Barbara J., Hémar, Agnès, McNiven, Mark A.·2003·Current Biology

DOI 10.1016/s0960-9822(03)00136-2

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Abstract

The dynamins comprise a large family of mechanoenzymes known to participate in membrane modeling events. All three conventional dynamin genes (Dyn1, Dyn2, Dyn3) are expressed in mammalian brain and produce more than 27 different dynamin proteins as a result of alternative splicing. Past studies have suggested that Dyn1 participates in specialized neuronal functions such as rapid synaptic vesicle recycling, while Dyn2 may mediate the conventional clathrin-mediated uptake of surface receptors. Currently, the distribution, expression, and function of Dyn3 in neurons, or in any other cell type, are completely undefined. Here, we demonstrate that Dyn1 and Dyn3 localize differentially in the synapse. Dyn1 concentrates within the presynaptic compartment, while Dyn3 localizes to dendritic spine tips. Within the postsynaptic density (PSD), we found Dyn3, but not Dyn1, to be part of a biochemically isolated complex comprised of Homer and metabotropic glutamate receptors. Finally, although dominant-negative Dyn3 did not seem to inhibit receptor endocytosis, overexpression of a specific Dyn3 spliced variant in mature neurons caused a marked remodeling of dendritic spines. These data suggest that Dyn3 is a postsynaptic dynamin and, like its binding partner Homer, plays a significant role in dendritic spine morphogenesis and remodeling.

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THE SYNAPTIC VESICLE CYCLE
Südhof, T. C. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131412 · Cited by 2,491
Induction of mutant dynamin specifically blocks endocytic coated vesicle formation.
Damke, H., Baba, T., Warnock, D. E., & Schmid, S. L. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.127.4.915 · Cited by 1,203
The rat brain postsynaptic density fraction contains a homolog of the drosophila discs-large tumor suppressor protein
Cho, K.-O., Hunt, C. A., & Kennedy, M. B. (1992) · Neuron · doi:10.1016/0896-6273(92)90245-9 · Cited by 1,188
Homer: a protein that selectively binds metabotropic glutamate receptors
Brakeman, P., Lanahan, A. A., O’Brien, R., Roche, K. W., Barnes, C. A., Huganir, R. L., & Worley, P. F. (1997) · Nature · doi:10.1038/386284a0 · Cited by 1,115
Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors
Tu, J. C., Xiao, B., Yuan, J. P., Lanahan, A. A., Leoffert, K., Li, M., Linden, D. J., & Worley, P. F. (1998) · Neuron · doi:10.1016/s0896-6273(00)80589-9 · Cited by 862
Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism
Xia, Z., Dudek, H., Miranti, C. K., & Greenberg, M. E. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-17-05425.1996 · Cited by 787
Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic
van der Bliek, A. M., & Meyerowrtz, E. M. (1991) · Nature · doi:10.1038/351411a0 · Cited by 776
Dynamin-mediated Internalization of Caveolae
Henley, J. R., Krueger, E. W. A., Oswald, B. J., & McNiven, M. A. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.141.1.85 · Cited by 767
Self-citation
Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis
Chen, M. S., Obar, R. A., Schroeder, C. C., Austin, T. W., Poodry, C. A., Wadsworth, S. C., & Vallee, R. B. (1991) · Nature · doi:10.1038/351583a0 · Cited by 558
Extraction of spots in biological images using multiscale products
Olivo‐Marín, J. (2002) · Pattern Recognition · doi:10.1016/s0031-3203(01)00127-3 · Cited by 540

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Ferguson, S. M., & Camilli, P. V. D. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3266 · Cited by 1,027
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Chowdhury, S., Shepherd, J. D., Okuno, H., Lyford, G., Petralia, R. S., Plath, N., Kuhl, D., Huganir, R. L., & Worley, P. F. (2006) · Neuron · doi:10.1016/j.neuron.2006.08.033 · Cited by 792
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Seyfried, N. T., Dammer, E. B., Swarup, V., Nandakumar, D., Duong, D. M., Yin, L., Deng, Q., Nguyen, T., Hales, C. M., Wingo, T., et al. (2017) · Cell Systems · doi:10.1016/j.cels.2016.11.006 · Cited by 477
Glutamate receptor dynamics in dendritic microdomains.
Newpher, T. M., & Ehlers, M. D. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.030 · Cited by 356
Regulation of GPCR activity, trafficking and localization by GPCR‐interacting proteins
Magalhães, A. C., Dunn, H. A., & Ferguson, S. S. G. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01552.x · Cited by 352
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Shiraishi‐Yamaguchi, Y., & Furuichi, T. (2007) · Genome biology · doi:10.1186/gb-2007-8-2-206 · Cited by 343
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Postsynaptic Positioning of Endocytic Zones and AMPA Receptor Cycling by Physical Coupling of Dynamin-3 to Homer
Lu, J., Helton, T. D., Blanpied, T. A., Rácz, B., Newpher, T. M., Weinberg, R. J., & Ehlers, M. D. (2007) · Neuron · doi:10.1016/j.neuron.2007.06.041 · Cited by 273
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Kruchten, A. E., & McNiven, M. A. (2006) · Journal of Cell Science · doi:10.1242/jcs.02963 · Cited by 123
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Morón, J. A., Abul‐Husn, N. S., Rozenfeld, R., Dolios, G., Wang, R., & Devi, L. A. (2006) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m600184-mcp200 · Cited by 116
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Campelo, F., & Malhotra, V. (2012) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-051710-094912 · Cited by 114
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Zala, D., Schlattner, U., Desvignes, T., Bobe, J., Roux, A., Chavrier, P., & Boissan, M. (2017) · F1000Research · doi:10.12688/f1000research.11561.2 · Cited by 79
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Ghazanfar, S., Lin, Y., Su, X., Lin, D. M., Patrick, E., Han, Z., Marioni, J. C., & Yang, J. Y. H. (2020) · Nature Methods · doi:10.1038/s41592-020-0885-x · Cited by 74
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Self-citation
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Yao, P. J. (2003) · Trends in Neurosciences · doi:10.1016/j.tins.2003.10.012 · Cited by 56
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Graham, M. E., Anggono, V., Bache, N., Larsen, M. R., Craft, G. E., & Robinson, P. J. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m609713200 · Cited by 53
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Smillie, K. J., & Cousin, M. A. (2005) · Biochemical Society Symposia · doi:10.1042/bss0720087 · Cited by 43
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Self-citation
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Ryan, M. M., Mason‐Parker, S. E., Tate, W. P., Abraham, W. C., & Williams, J. M. (2010) · Hippocampus · doi:10.1002/hipo.20770 · Cited by 43
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Authors: Gray, N. W., Fourgeaud, L., Huang, B., Chen, J., Cao, H., Oswald, B. J., Hémar, A., & McNiven, M. A.
Affiliations: Mayo Clinic (US)
Centre National de la Recherche Scientifique (FR)
Corresponding author: McNiven, Mark A.
ORCID: Gray, Noah W.
Huang, Bing
Chen, Jing
Cao, Hong
McNiven, Mark A.
Venue: Current Biology
Publisher: Elsevier BV
Published: 2003-03
Volume: 13
Issue: 6
Pages: 510-515
ISSN: 0960-9822 (ISSN-L)
DOI: 10.1016/s0960-9822(03)00136-2
OpenAlex: W2086499290
Cited by: 143
References: 33
Citations by year: 2026: 1 · 2025: 1 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 1 · 2019: 3 · 2018: 4 · 2017: 6 · 2016: 5 · 2015: 5 · 2014: 6 · 2013: 12 · 2012: 8
FWCI: 4.27
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 3791 d)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: Current Biology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5t32ns007424-05)
National Institute of Neurological Disorders and Stroke (NS07424)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Keywords: DNM3, postsynaptic density, metabotropic glutamate receptor 5, Homer, dendritic spines, spine morphogenesis, dynamin 1, alternative splicing, receptor internalization, synaptic localization
MeSH terms: Homer Scaffolding Proteins, Amino Acid Sequence, Animals, Carrier Proteins, Dendrites, Microscopy, Fluorescence, Molecular Sequence Data, Neuropeptides, Protein Binding, Synapses, Sequence Homology, Amino Acid, Presynaptic Terminals, Kainic Acid Receptors, Protein Transport, Dynamin I, Dynamin III, Rats

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Dynamin 3 Is a Component of the Postsynapse, Where it Interacts with mGluR5 and Homer

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