Activation Domain–Mediated Targeting of the SWI/SNF Complex to Promoters Stimulates Transcription from Nucleosome Arrays
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The yeast SWI/SNF complex is required for the transcription of several yeast genes and has been shown to alter nucleosome structure in an ATP-dependent reaction. In this study, we show that the complex stimulated in vitro transcription from nucleosome templates in an activation domain-dependent manner. Transcription stimulation by SWI/SNF required an activation domain with which it directly interacts. The acidic activation domains of VP16, Gcn4, Swi5, and Hap4 interacted directly with the purified SWI/SNF complex and with the SWI/SNF complex in whole-cell extracts. The similarity of activation domain interactions and transcriptional stimulation between SWI/SNF and the SAGA histone acetyltransferase complex may account for their apparent overlapping functions in vivo.
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VP48 is known to directly interact with chromatin-remodeling cofactors.
“Because VP48 is known to directly interact with chromatin-remodeling cofactors21–23”
From Single-molecule states link transcription factor binding to gene expression (2024) · cites this paper as [23]
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ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION
Workman, J. L., & Kingston, R. E. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.545 · Cited by 1,129 · see citing works
Self-citationStimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex
Côté, J., Quinn, J., Workman, J. L., & Peterson, C. L. (1994) · Science · doi:10.1126/science.8016655 · Cited by 861 · see citing works
Self-citationTriezenberg, S., Kingsbury, R., & McKnight, S. (1988) · Genes & Development · doi:10.1101/gad.2.6.718 · Cited by 785 · see citing works
Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex
Kwon, H., Imbalzano, A. N., Khavari, P. A., Kingston, R. E., & Green, M. R. (1994) · Nature · doi:10.1038/370477a0 · Cited by 780 · see citing works
Cosma, M. P., Tanaka, T. U., & Nasmyth, K. (1999) · Cell · doi:10.1016/s0092-8674(00)80740-0 · Cited by 693 · see citing works
RSC, an Essential, Abundant Chromatin-Remodeling Complex
Cairns, B. R., Lorch, Y., Li, Y., Zhang, M., Lacomis, L., Erdjument‐Bromage, H., Tempst, P., Du, J., Laurent, B. C., & Kornberg, R. D. (1996) · Cell · doi:10.1016/s0092-8674(00)81820-6 · Cited by 667 · see citing works
Self-citationPeterson, C. L., & Herskowitz, I. (1992) · Cell · doi:10.1016/0092-8674(92)90192-f · Cited by 601 · see citing works
Neigeborn, L., & Carlson, M. (1984) · Genetics · doi:10.1093/genetics/108.4.845 · Cited by 587 · see citing works
Ikaros DNA-Binding Proteins Direct Formation of Chromatin Remodeling Complexes in Lymphocytes
Kim, J., Sif, S., Jones, B., Jackson, A., Koipally, J., Heller, E., Winandy, S., Viel, A., Sawyer, A., Ikeda, T., et al. (1999) · Immunity · doi:10.1016/s1074-7613(00)80034-5 · Cited by 587 · see citing works
Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex
Fryer, C. J., & Archer, T. K. (1998) · Nature · doi:10.1038/30032 · Cited by 511 · see citing works
Transcriptional activators direct histone acetyltransferase complexes to nucleosomes
Utley, R. T., Ikeda, K., Grant, P. A., Côté, J., Steger, D. J., Eberharter, A., John, S., & Workman, J. L. (1998) · Nature · doi:10.1038/28886 · Cited by 499 · see citing works
Self-citationRoles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors
Yoshinaga, S. K., Peterson, C. L., Herskowitz, I., & Yamamoto, K. R. (1992) · Science · doi:10.1126/science.1360703 · Cited by 477 · see citing works
Five SWI genes are required for expression of the HO gene in yeast
Stern, M., Jensen, R. E., & Herskowitz, I. (1984) · Journal of Molecular Biology · doi:10.1016/0022-2836(84)90315-2 · Cited by 464 · see citing works
Critical structural elements of the VP16 transcriptional activation domain.
Cress, W., & Triezenberg, S. (1991) · Science · doi:10.1126/science.1846049 · Cited by 414 · see citing works
Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulators
Breeden, L. L., & Nasmyth, K. (1987) · Cell · doi:10.1016/0092-8674(87)90190-5 · Cited by 390 · see citing works
RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling
Wilson, C. J., Chao, D. M., Imbalzano, A. N., Schnitzler, G. R., Kingston, R. E., & Young, R. A. (1996) · Cell · doi:10.1016/s0092-8674(00)80978-2 · Cited by 364 · see citing works
Nucleosome mobilization catalysed by the yeast SWI/SNF complex
Whitehouse, I., Flaus, A., Cairns, B. R., White, M. F., Workman, J. L., & Owen‐Hughes, T. (1999) · Nature · doi:10.1038/23506 · Cited by 356 · see citing works
Self-citationCoactivators for a proline-rich activator purified from the multisubunit human TFIID complex.Preprint
Tanese, N., Pugh, B., & Tjian, R. (1991) · Genes & Development · doi:10.1101/gad.5.12a.2212 · Cited by 316 · see citing works
Laurent, B. C., Treich, I., & Carlson, M. (1993) · Genes & Development · doi:10.1101/gad.7.4.583 · Cited by 308 · see citing works
Armstrong, J. A., Bieker, J. J., & Emerson, B. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81785-7 · Cited by 303 · see citing works
Histone Octamer Transfer by a Chromatin-Remodeling Complex
Lorch, Y., Zhang, M., & Kornberg, R. D. (1999) · Cell · doi:10.1016/s0092-8674(00)80551-6 · Cited by 301 · see citing works
Human SWI/SNF Interconverts a Nucleosome between Its Base State and a Stable Remodeled State
Schnitzler, G. R., Sif, S., & Kingston, R. E. (1998) · Cell · doi:10.1016/s0092-8674(00)81217-9 · Cited by 282 · see citing works
Roberts, S. M., & Winston, F. (1997) · Genetics · doi:10.1093/genetics/147.2.451 · Cited by 278 · see citing works
Cell cycle-regulated histone acetylation required for expression of the yeast HO gene
Krebs, J. E., Kuo, M.-H., Allis, C. D., & Peterson, C. L. (1999) · Genes & Development · doi:10.1101/gad.13.11.1412 · Cited by 275 · see citing works
Berger, S., Cress, W., Cress, A., Triezenberg, S., & Guarente, L. (1990) · Cell · doi:10.1016/0092-8674(90)90684-7 · Cited by 271 · see citing works
Regier, J. L., Shen, F., & Triezenberg, S. J. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.3.883 · Cited by 261 · see citing works
GAL4 derivatives function alone and synergistically with mammalian activators in vitro
Lin, Y.-S., Carey, M., Ptashne, M., & Green, M. R. (1988) · Cell · doi:10.1016/s0092-8674(88)80010-2 · Cited by 257 · see citing works
Persistent Site-Specific Remodeling of a Nucleosome Array by Transient Action of the SWI/SNF Complex
Owen‐Hughes, T., Utley, R. T., Côté, J., Peterson, C. L., & Workman, J. L. (1996) · Science · doi:10.1126/science.273.5274.513 · Cited by 224 · see citing works
Self-citationActivator-dependent regulation of transcriptional pausing on nucleosomal templates.Preprint
Brown, S. A., Imbalzano, A. N., & Kingston, R. E. (1996) · Genes & Development · doi:10.1101/gad.10.12.1479 · Cited by 209 · see citing works
Cairns, B. R., Erdjument‐Bromage, H., Tempst, P., Winston, F., & Kornberg, R. D. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80162-8 · Cited by 209 · see citing works
Self-citationRole for ADA/GCN5 Products in Antagonizing Chromatin-Mediated Transcriptional Repression
Pollard, K. J., & Peterson, C. L. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.11.6212 · Cited by 202 · see citing works
DNA-binding properties of the yeast SWI/SNF complex
Quinn, J., Fyrberg, A. M., Ganster, R. W., Schmidt, M. C., & Peterson, C. L. (1996) · Nature · doi:10.1038/379844a0 · Cited by 194 · see citing works
Activated RSC–Nucleosome Complex and Persistently Altered Form of the Nucleosome
Lorch, Y., Cairns, B. R., Zhang, M., & Kornberg, R. D. (1998) · Cell · doi:10.1016/s0092-8674(00)81218-0 · Cited by 191 · see citing works
Self-citationActivation of Yeast Polymerase II Transcription by Herpesvirus VP16 and GAL4 Derivatives In Vitro
Chasman, D. I., Leatherwood, J., Carey, M., Ptashne, M., & Kornberg, R. D. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.11.4746 · Cited by 187 · see citing works
Côté, J., Peterson, C. L., & Workman, J. L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.9.4947 · Cited by 180 · see citing works
Self-citationCatalytic activity of the yeast SWI/SNF complex on reconstituted nucleosome arrays
Logie, C., & Peterson, C. L. (1997) · The EMBO Journal · doi:10.1093/emboj/16.22.6772 · Cited by 179 · see citing works
Yeast TAF IIS in a multisubunit complex required for activated transcription
Reese, J. C., Apone, L., Walker, S. S., Griffin, L. A., & Green, M. R. (1994) · Nature · doi:10.1038/371523a0 · Cited by 168 · see citing works
Cairns, B. R., Henry, N. L., & Kornberg, R. D. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.7.3308 · Cited by 162 · see citing works
Self-citationIkeda, K., Steger, D. J., Eberharter, A., & Workman, J. L. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.855 · Cited by 156 · see citing works
Self-citationNatarajan, K., Jackson, B. M., Zhou, H., Winston, F., & Hinnebusch, A. G. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80217-8 · Cited by 155 · see citing works
Bazett‐Jones, D. P., Côté, J., Landel, C. C., Peterson, C. L., & Workman, J. L. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.2.1470 · Cited by 146 · see citing works
Self-citationLaurent, B. C., Treitel, M. A., & Carlson, M. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.11.5616 · Cited by 141 · see citing works
Subunits of the Yeast SWI/SNF Complex Are Members of the Actin-related Protein (ARP) Family
Peterson, C. L., Zhao, Y., & Chait, B. T. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.37.23641 · Cited by 136 · see citing works
Steger, D. J., Eberharter, A., John, S., Grant, P. A., & Workman, J. L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.12924 · Cited by 124 · see citing works
Self-citationEssential role of Swp73p in the function of yeast Swi/Snf complex.Preprint
Cairns, B. R., Levinson, R. S., Yamamoto, K. R., & Kornberg, R. D. (1996) · Genes & Development · doi:10.1101/gad.10.17.2131 · Cited by 117 · see citing works
Self-citationContinuous and widespread roles for the Swi–Snf complex in transcription
Biggar, S. R., & Crabtree, G. R. (1999) · The EMBO Journal · doi:10.1093/emboj/18.8.2254 · Cited by 103 · see citing works
Nucleosome Disruption by Human SWI/SNF Is Maintained in the Absence of Continued ATP Hydrolysis
Imbalzano, A. N., Schnitzler, G. R., & Kingston, R. E. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.34.20726 · Cited by 94 · see citing works
[6] Basic analysis of transcription factor binding to nucleosomes
Côté, J., Utley, R. T., & Workman, J. L. (1995) · Methods in molecular genetics · doi:10.1016/s1067-2389(06)80009-9 · Cited by 92 · see citing works
Self-citationTranscriptional Activation in an Improved Whole-Cell Extract from Saccharomyces cerevisiae
Woontner, M., Wade, P. A., Bonner, J. J., & Jaehning, J. A. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.9.4555 · Cited by 90 · see citing works
Logie, C., Tse, C., Hansen, J. C., & Peterson, C. L. (1999) · Biochemistry · doi:10.1021/bi982109d · Cited by 77 · see citing works
H1-mediated Repression of Transcription Factor Binding to a Stably Positioned Nucleosome
Juan, L., Utley, R. T., Vignali, M., Böhm, L., & Workman, J. L. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.6.3635 · Cited by 51 · see citing works
Self-citationEnergy-Dependent Chromatin Remodelers: Complex Complexes and Their Components
Imbalzano, A. N. (1998) · Critical Reviews in Eukaryotic Gene Expression · doi:10.1615/critreveukargeneexpr.v8.i3-4.10 · Cited by 50 · see citing works
Transcriptional Analysis of Purified Histone Acetyltransferase Complexes
Steger, D. J., & Workman, J. L. (1999) · Methods · doi:10.1006/meth.1999.0877 · Cited by 42 · see citing works
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Konermann, S., Brigham, M. D., Trevino, A. E., Joung, J., Abudayyeh, O. O., Barcena, C., Hsu, P. D., Habib, N., Gootenberg, J. S., Nishimasu, H., et al. (2015) · Nature · doi:10.1038/nature14136 · Cited by 2,825 · see citing works
Nuclear Hormone Receptors and Gene Expression
Aranda, A., & Pascual, A. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.3.1269 · Cited by 1,562 · see citing works
Cooperation between Complexes that Regulate Chromatin Structure and Transcription
Narlikar, G. J., Fan, H.-Y., & Kingston, R. E. (2002) · Cell · doi:10.1016/s0092-8674(02)00654-2 · Cited by 1,486 · see citing works
Opening of Compacted Chromatin by Early Developmental Transcription Factors HNF3 (FoxA) and GATA-4
Cirillo, L. A., Lin, F. R., Cuesta, I., Friedman, D., Jarník, M., & Zaret, K. S. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00459-8 · Cited by 1,188 · see citing works
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Becker, P. B., & Hörz, W. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.110601.135400 · Cited by 790 · see citing works
ATP-Dependent Chromatin-Remodeling Complexes
Vignali, M., Hassan, A. H., Neely, K. E., & Workman, J. L. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.6.1899-1910.2000 · Cited by 731 · see citing works
Self-citationZhang, H. S., Gavin, M., Dahiya, A., Postigo, A. A., Ma, D., Luo, R. X., Harbour, J. W., & Dean, D. C. (2000) · Cell · doi:10.1016/s0092-8674(00)80625-x · Cited by 658 · see citing works
Transcriptional coactivator complexes.
Näär, A. M., Lemon, B. D., & Tjian, R. (2001) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.70.1.475 · Cited by 571 · see citing works
Kim, M. Y., Mauro, S. A., Gévry, N. Y., Lis, J. T., & Kraus, W. L. (2004) · Cell · doi:10.1016/j.cell.2004.11.002 · Cited by 551 · see citing works
Hassan, A. H., Prochasson, P., Neely, K. E., Galasinski, S. C., Chandy, M., Carrozza, M. J., & Workman, J. L. (2002) · Cell · doi:10.1016/s0092-8674(02)01005-x · Cited by 533 · see citing works
Self-citationPost-Translational Modifications of Histones That Influence Nucleosome Dynamics
Bowman, G., & Poirier, M. (2014) · Chemical Reviews · doi:10.1021/cr500350x · Cited by 461 · see citing works
Functional selectivity of recombinant mammalian SWI/SNF subunitsPreprint
Kadam, S., McAlpine, G. S., Phelan, M. L., Kingston, R. E., Jones, K. A., & Emerson, B. M. (2000) · Genes & Development · doi:10.1101/gad.828000 · Cited by 497 · see citing works
Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated <i>Myc</i> regulation
Shi, J., Whyte, W. A., Zepeda-Mendoza, C. J., Milazzo, J. P., Shen, C., Roe, J.-S., Minder, J. L., Mercan, F., Wang, E., Eckersley-Maslin, M. A., et al. (2013) · Genes & Development · doi:10.1101/gad.232710.113 · Cited by 463 · see citing works
Promoter targeting and chromatin remodeling by the SWI/SNF complex
Peterson, C. L., & Workman, J. L. (2000) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(00)00068-x · Cited by 438 · see citing works
Self-citationHistones Are First Hyperacetylated and Then Lose Contact with the Activated PHO5 Promoter
Reinke, H., & Hörz, W. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00186-2 · Cited by 394 · see citing works
Whole-genome expression analysis of <i>snf/swi</i> mutants of <i>Saccharomyces</i> <i>cerevisiae</i>
Sudarsanam, P., Iyer, V. R., Brown, P. O., & Winston, F. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.7.3364 · Cited by 389 · see citing works
Li, B., Howe, L. J., Anderson, S., Yates, J. R., & Workman, J. L. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212134200 · Cited by 371 · see citing works
Self-citationHistone Acetyltransferase Complexes Stabilize SWI/SNF Binding to Promoter Nucleosomes
Hassan, A. H., Neely, K. E., & Workman, J. L. (2001) · Cell · doi:10.1016/s0092-8674(01)00279-3 · Cited by 365 · see citing works
Self-citationRegulation of Chromatin Remodeling by Inositol Polyphosphates
Steger, D. J., Haswell, E. S., Miller, A. L., Wente, S. R., & O'Shea, E. K. (2003) · Science · doi:10.1126/science.1078062 · Cited by 352 · see citing works
Self-citationProft, M., & Struhl, K. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00557-9 · Cited by 350 · see citing works
Sudarsanam, P., & Winston, F. (2000) · Trends in Genetics · doi:10.1016/s0168-9525(00)02060-6 · Cited by 347 · see citing works
Sekinger, E. A., Moqtaderi, Z., & Struhl, K. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.05.003 · Cited by 334 · see citing works
Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexesPreprint
Sif, S., Saurin, A. J., Imbalzano, A. N., & Kingston, R. E. (2001) · Genes & Development · doi:10.1101/gad.872801 · Cited by 283 · see citing works
Chromatin remodeling enzymes: who's on first?
Fry, C. J., & Peterson, C. L. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00090-2 · Cited by 266 · see citing works
Cosma, M. P. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00604-4 · Cited by 261 · see citing works
Global Role for Chromatin Remodeling Enzymes in Mitotic Gene Expression
Krebs, J. E., Fry, C. J., Samuels, M. L., & Peterson, C. L. (2000) · Cell · doi:10.1016/s0092-8674(00)00081-7 · Cited by 237 · see citing works
Lee, D., Kim, J. W., Seo, T., Hwang, S. G., Choi, E., & Choe, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111987200 · Cited by 230 · see citing works
Adam, M., Robert, F., Larochelle, M., & Gaudreau, L. R. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.18.6270-6279.2001 · Cited by 228 · see citing works
The “Dark Side” of Chromatin Remodeling
Tyler, J. K., & Kadonaga, J. T. (1999) · Cell · doi:10.1016/s0092-8674(00)81530-5 · Cited by 223 · see citing works
Cliffe, A. R., & Knipe, D. M. (2008) · Journal of Virology · doi:10.1128/jvi.01575-08 · Cited by 210 · see citing works
Herrera, F. J., & Triezenberg, S. J. (2004) · Journal of Virology · doi:10.1128/jvi.78.18.9689-9696.2004 · Cited by 210 · see citing works
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Syntichaki, P., Topalidou, I., & Thireos, G. (2000) · Nature · doi:10.1038/35006136 · Cited by 195 · see citing works
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Transcription Activator Interactions with Multiple SWI/SNF Subunits
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Self-citationZhang, W., Kadam, S., Emerson, B. M., & Bieker, J. J. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.7.2413-2422.2001 · Cited by 182 · see citing works
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Neumann, F. R., Dion, V., Gehlen, L. R., Tsai-Pflugfelder, M., Schmid, R., Taddei, A., & Gasser, S. M. (2012) · Genes & Development · doi:10.1101/gad.176156.111 · Cited by 173 · see citing works
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Kal, A. J., Mahmoudi, T., Zak, N. B., & Verrijzer, C. P. (2000) · Genes & Development · doi:10.1101/gad.14.9.1058 · Cited by 169 · see citing works
Travis, J. T. (2002) · Frontiers in bioscience · doi:10.2741/taylor · Cited by 166 · see citing works
Lee, D., Ezhkova, E., Li, B., Pattenden, S. G., Tansey, W. P., & Workman, J. L. (2005) · Cell · doi:10.1016/j.cell.2005.08.015 · Cited by 178 · see citing works
Self-citationIto, T., Yamauchi, M., Nishina, M., Yamamichi, N., Mizutani, T., Ui, M., Murakami, M., & Iba, H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009633200 · Cited by 162 · see citing works
Schwabish, M. A., & Struhl, K. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00717-07 · Cited by 158 · see citing works
Natarajan, K., Jackson, B. M., Zhou, H., Winston, F., & Hinnebusch, A. G. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80217-8 · Cited by 155 · see citing works
Rullan, M., Benzinger, D., Schmidt, G. W., Gupta, A., Milias‐Argeitis, A., & Khammash, M. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.04.012 · Cited by 147 · see citing works
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Hall, D. B., & Struhl, K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m208911200 · Cited by 142 · see citing works
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Shivaswamy, S., & Iyer, V. R. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.01659-07 · Cited by 139 · see citing works
Architecture of the SWI/SNF-Nucleosome Complex
Dechassa, M. L., Zhang, B., Horowitz-Scherer, R. A., Persinger, J., Woodcock, C. L. F., Peterson, C. L., & Bartholomew, B. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00693-08 · Cited by 139 · see citing works
Minderjahn, J., Schmidt, A., Fuchs, A., Schill, R., Raithel, J., Babina, M., Schmidl, C., Gebhard, C., Schmidhofer, S., Mendes, K., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-13960-2 · Cited by 136 · see citing works
Wallberg, A. E., Neely, K. E., Hassan, A. H., Gustafsson, J.-Α., Workman, J. L., & Wright, A. P. H. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.6.2004-2013.2000 · Cited by 134 · see citing works
Self-citationATP-dependent chromatin remodeling factors: Nucleosome shufflers with many missions
Varga‐Weisz, P. (2001) · Oncogene · doi:10.1038/sj.onc.1204332 · Cited by 132 · see citing works
Promoter targeting of chromatin-modifying complexes
Ahmed, H. H. (2001) · Frontiers in bioscience · doi:10.2741/hassan · Cited by 129 · see citing works
The Swi5 activator recruits the Mediator complex to theHOpromoter without RNA polymerase IIPreprint
Bhoite, L. T., Yu, Y., & Stillman, D. J. (2001) · Genes & Development · doi:10.1101/gad.921601 · Cited by 129 · see citing works
Transcriptional Activation Domains of Human Heat Shock Factor 1 Recruit Human SWI/SNF
Sullivan, E. K., Weirich, C. S., Guyon, J. R., Sif, S., & Kingston, R. E. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.17.5826-5837.2001 · Cited by 125 · see citing works
Yang, F., deBeaumont, R. S., Zhou, S., & Näär, A. M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308676100 · Cited by 123 · see citing works
Inoue, H., Furukawa, T., Giannakopoulos, S., Zhou, S., King, D., & Tanese, N. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205961200 · Cited by 122 · see citing works
Distribution of acetylated histones resulting from Gal4‐VP16 recruitment of SAGA and NuA4 complexes
Vignali, M., Steger, D. J., Neely, K. E., & Workman, J. L. (2000) · The EMBO Journal · doi:10.1093/emboj/19.11.2629 · Cited by 121 · see citing works
Self-citationKing, I. F. G., Francis, N. J., & Kingston, R. E. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.22.7919-7928.2002 · Cited by 120 · see citing works
Compendium of human transcription factor effector domains
Soto, L. F., Li, Z., Santoso, C., Berenson, A., Ho, I., Shen, V. X., Yuan, S., & Bass, J. I. F. (2021) · Molecular Cell · doi:10.1016/j.molcel.2021.11.007 · Cited by 111 · see citing works
Jónsson, Z. O., Dhar, S. K., Narlikar, G. J., Auty, R., Wagle, N., Pellman, D. S., Pratt, R. E., Kingston, R. E., & Dutta, A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m011523200 · Cited by 116 · see citing works
Interferon‐γ‐induced chromatin remodeling at the CIITA locus is BRG1 dependent
Pattenden, S. G., Klose, R. J., Karaskov, E., & Bremner, R. (2002) · The EMBO Journal · doi:10.1093/emboj/21.8.1978 · Cited by 116 · see citing works
Phelan, M. L., Schnitzler, G. R., & Kingston, R. E. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.17.6380-6389.2000 · Cited by 116 · see citing works
FACT and Asf1 Regulate Nucleosome Dynamics and Coactivator Binding at the HO Promoter
Takahata, S., Yu, Y., & Stillman, D. J. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.04.010 · Cited by 114 · see citing works
Kato, H., Tjernberg, A., Zhang, W., Krutchinsky, A. N., An, W., Takeuchi, T., Ohtsuki, Y., Sugano, S., de Bruijn, D. R. H., Chait, B. T., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m108702200 · Cited by 114 · see citing works
Dissection of the unusual structural and functional properties of the variant H2A.Bbd nucleosome
Doyen, C.-M., Montel, F., Gautier, T., Menoni, H., Claudet, C., Delacour‐Larose, M., Angelov, D., Hamiche, A., Bednář, J., Faivre-Moskalenko, C., et al. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601310 · Cited by 113 · see citing works
CRISPR-mediated Activation of Latent HIV-1 Expression
Limsirichai, P., Gaj, T., & Schaffer, D. V. (2015) · Molecular Therapy · doi:10.1038/mt.2015.213 · Cited by 109 · see citing works
Activation domains drive nucleosome eviction by SWI/SNF
Gutiérrez, J. L., Chandy, M., Carrozza, M. J., & Workman, J. L. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601524 · Cited by 102 · see citing works
Self-citationProchasson, P., Neely, K. E., Hassan, A. H., Li, B., & Workman, J. L. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00366-6 · Cited by 97 · see citing works
Self-citationSWI/SNF Displaces SAGA-Acetylated Nucleosomes
Chandy, M., Gutiérrez, J. L., Prochasson, P., & Workman, J. L. (2006) · Eukaryotic Cell · doi:10.1128/ec.00165-06 · Cited by 96 · see citing works
Self-citationRole of Toll-like receptor responses for sepsis pathogenesis
Weighardt, H., & Holzmann, B. (2007) · Immunobiology · doi:10.1016/j.imbio.2007.09.010 · Cited by 95 · see citing works
Guermah, M., Palhan, V. B., Tackett, A. J., Chait, B. T., & Roeder, R. G. (2006) · Cell · doi:10.1016/j.cell.2006.01.055 · Cited by 94 · see citing works
Structure and functions of powerful transactivators: VP16, MyoD and FoxA
Hirai, H., Tani, T., & Kikyo, N. (2010) · The International Journal of Developmental Biology · doi:10.1387/ijdb.103194hh · Cited by 89 · see citing works
Histone Octamer Instability under Single Molecule Experiment Conditions
Claudet, C., Angelov, D., Bouvet, P., Dimitrov, S. I., & Bednář, J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m500121200 · Cited by 90 · see citing works
Transcriptional activators in yeast
Titz, B. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkj493 · Cited by 90 · see citing works
Chromatin inheritance upon Zeste‐mediated Brahma recruitment at a minimal cellular memory module
Déjardin, J., & Cavalli, G. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600108 · Cited by 89 · see citing works
Selective recognition of acetylated histones by bromodomains in transcriptional co-activators
Hassan, A. H., Awad, S. M., Natour, Z. A., Othman, S., Mustafa, F., & Rizvi, T. A. (2007) · Biochemical Journal · doi:10.1042/bj20060907 · Cited by 88 · see citing works
Self-citationSchnitzler, G. R., Cheung, C. L., Hafner, J. H., Saurin, A. J., Kingston, R. E., & Lieber, C. M. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.24.8504-8511.2001 · Cited by 86 · see citing works
Duan, M., & Smerdon, M. J. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.540732 · Cited by 84 · see citing works
Doan, D. N., Veal, T. M., Yan, Z., Wang, W., Jones, S. N., & Imbalzano, A. N. (2004) · Oncogene · doi:10.1038/sj.onc.1207472 · Cited by 78 · see citing works
SWI/SNF-dependent chromatin remodeling ofRNR3requires TAFIIs and the general transcription machineryPreprint
Sharma, V. M., Li, B., & Reese, J. C. (2003) · Genes & Development · doi:10.1101/gad.1039503 · Cited by 78 · see citing works
Angers, M., Drouin, R., Bachvarova, M., Paradis, I., Marceau, F., & Bachvarov, D. R. (2000) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(20000801)78:2 · Cited by 25 · see citing works
Sentani, K., Oue, N., Kondo, H., Kuraoka, K., Motoshita, J., Ito, R., Yokozaki, H., & Yasui, W. (2001) · Pathobiology · doi:10.1159/000064638 · Cited by 76 · see citing works
BRG1-Mediated Chromatin Remodeling Regulates Differentiation and Gene Expression of T Helper Cells
Wurster, A. L., & Pazin, M. J. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00835-08 · Cited by 72 · see citing works
Daughter‐specific repression of Saccharomyces cerevisiae HO: Ash1 is the commander
Cosma, M. P. (2004) · EMBO Reports · doi:10.1038/sj.embor.7400251 · Cited by 72 · see citing works
CHD8 Associates with Human Staf and Contributes to Efficient U6 RNA Polymerase III Transcription
Yuan, C.-C., Zhao, X., Florens, L. A., Swanson, S. K., Washburn, M. P., & Hernandez, N. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00846-07 · Cited by 72 · see citing works
Lacasse, J. J., & Schang, L. M. (2009) · Journal of Virology · doi:10.1128/jvi.01934-09 · Cited by 71 · see citing works
Morillon, A., Bénard, L., Springer, M., & Lesage, P. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.7.2078-2088.2002 · Cited by 71 · see citing works
Mechanism of Transcription Factor Recruitment by Acidic Activators
Ferreira, M. E., Hermann, S., Prochasson, P., Workman, J. L., Berndt, K. D., & Wright, A. P. H. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502627200 · Cited by 71 · see citing works
Self-citationH2A.Z has a function reminiscent of an activator required for preferential binding to intergenic DNA
Larochelle, M., & Gaudreau, L. R. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg427 · Cited by 71 · see citing works
Neurospora WC-1 Recruits SWI/SNF to Remodel frequency and Initiate a Circadian Cycle
Wang, B., Kettenbach, A. N., Gerber, S. A., Loros, J., & Dunlap, J. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004599 · Cited by 70 · see citing works
Monitoring the spatio-temporal organization and dynamics of the genome
Shaban, H., & Seeber, A. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa135 · Cited by 68 · see citing works
Human SWI/SNF Generates Abundant, Structurally Altered Dinucleosomes on Polynucleosomal Templates
Ulyanova, N. P., & Schnitzler, G. R. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.24.11156-11170.2005 · Cited by 70 · see citing works
Promoter-Specific Targeting of Human SWI-SNF Complex by Epstein-Barr Virus Nuclear Protein 2
Wu, D. Y., Krumm, A., & Schubach, W. H. (2000) · Journal of Virology · doi:10.1128/jvi.74.19.8893-8903.2000 · Cited by 70 · see citing works
Actin-related proteins in the nucleus: life beyond chromatin remodelers
Dion, V., Shimada, K., & Gasser, S. M. (2010) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2010.02.006 · Cited by 69 · see citing works
Kim, J. M., Visanpattanasin, P., Jou, V., Liu, S., Tang, X., Zheng, Q., Li, K. Y., Snedeker, J. C., Lavis, L. D., Lionnet, T., et al. (2021) · eLife · doi:10.7554/elife.69387 · Cited by 64 · see citing works
Recruitment of Transcription Complexes to the β-Globin Gene Locus in Vivo and in Vitro
Vieira, K. F., Levings, P. P., Hill, M. A., Crusselle‐Davis, V. J., Kang, S.-H. L., Engel, J. D., & Bungert, J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408883200 · Cited by 68 · see citing works
Hassan, A. H., Awad, S. M., & Prochasson, P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602851200 · Cited by 67 · see citing works
Self-citation
- Authors
- Neely, K. E., Hassan, A. H., Wallberg, A. E., Steger, D. J., Cairns, B. R., Wright, A. P. H., & Workman, J. L.
- Affiliations
- Pennsylvania State University (US)
- Södertörn University (SE)
- University of Utah (US)
- Corresponding author
- Workman, Jerry L
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 1999-10
- Volume
- 4
- Issue
- 4
- Pages
- 649-655
- ISSN
- 1097-2765 (ISSN-L)
- OpenAlex
- W2119383396
- Cited by
- 245
- References
- 53
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 8 · 2023: 3 · 2022: 5 · 2021: 6 · 2020: 7 · 2019: 2 · 2018: 5 · 2017: 1 · 2016: 4 · 2015: 1 · 2014: 8 · 2013: 2 · 2012: 5
- FWCI
- 9.13
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Molecular Cell (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Chromatin Remodeling and Cancer
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nuclear Structure and Function
- Keywords
- SWI/SNF complex, chromatin remodeling, transactivation domain, nucleosome arrays, transcription initiation, nucleosome structure, SAGA complex, histone acetyltransferase, protein-protein interaction, Swi5, HAP4, GCN4, VP16
- MeSH terms
- Chromatin, DNA-Binding Proteins, Fungal Proteins, Nuclear Proteins, Nucleosomes, Promoter Regions, Genetic, Protein Kinases, Recombinant Proteins, Transcription Factors, Yeasts, Transcriptional Activation, Gene Expression Regulation, Fungal, Herpes Simplex Virus Protein Vmw65, Cell Cycle Proteins, CCAAT-Binding Factor, Saccharomyces cerevisiae Proteins
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