ASPP Proteins Specifically Stimulate the Apoptotic Function of p53

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Cytoplasmic iASPP Expression as a Novel Prognostic Indicator in Oral Cavity Squamous Cell Carcinoma

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Linking Co-regulated Gene Modules with Polycyclic Aromatic Hydrocarbon-related Cancer Risk in the 3D Human Bronchial Epithelium

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Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis

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p53 Target DDA3 binds ASPP2 and inhibits its stimulation on p53-mediated BAX activation

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The ASPP interaction network: electrostatic differentiation between pro‐ and anti‐apoptotic proteins

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Expression pattern of the apoptosis-stimulating protein of p53 family in p53+ human breast cancer cell lines

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The Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling Pathway

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Formation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elements †

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Mutational Analysis of ASPP1 and ASPP2 Genes, a p53-related Gene, in Gastric and Cololorectal Cancers with Microsatellite Instability

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The adapter protein CD2AP binds to p53 protein in the cytoplasm and can discriminate its polymorphic variants P72R

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ΔN-ASPP2, a novel isoform of the ASPP2 tumor suppressor, promotes cellular survival

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The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53

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Determination of Dysregulated miRNA Expression Levels by qRT-PCR after the Application of Usnic Acid to Breast Cancer

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TFIIS.h, a new target of p53, regulates transcription efficiency of pro-apoptotic bax gene

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ASPP2 suppresses stem cell-like characteristics and chemoresistance by inhibiting the Src/FAK/Snail axis in hepatocellular carcinoma

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Effect of miR-21 on apoptosis in hepatoblastoma cell through activating ASPP2/p38 signaling pathway in vitro and in vivo

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Proteome profiling of different rat brain regions reveals the modulatory effect of prolonged maternal separation on proteins involved in cell death-related processes

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Identification of a Function-Specific Mutation of Clathrin Heavy Chain (CHC) Required for p53 Transactivation

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ASPP1 deficiency promotes epithelial-mesenchymal transition, invasion and metastasis in colorectal cancer

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Recent Candidate Molecular Markers: Vitamin D Signaling and Apoptosis Specific Regulator of p53 (ASPP) in Breast Cancer

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ASPP2 inhibits hepatitis B virus replication by preventing nucleus translocation of HSF1 and attenuating the transactivation of ATG7

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Investigation on the Potential Correlation Between TP53 and Esophageal Cancer

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A Screen for Extracellular Signal-Regulated Kinase-Primed Glycogen Synthase Kinase 3 Substrates Identifies the p53 Inhibitor iASPP

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An Intrinsically Disordered Region in the Proapoptotic ASPP2 Protein Binds to the Helicobacter pylori Oncoprotein CagA

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The Caenorhabditis elegans ASPP homolog APE-1 is a junctional protein phosphatase 1 modulator

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Phosphoproteomics Combined with Quantitative 14-3-3-affinity Capture Identifies SIRT1 and RAI as Novel Regulators of Cytosolic Double-stranded RNA Recognition Pathway

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Regulation of p53 isoform expression in renal cell carcinoma

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iASPP overexpression is associated with clinical outcome in spinal chordoma and influences cellular proliferation, invasion, and sensitivity to cisplatinin vitro

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Mdm2 and mdmX prevent ASPP1 and ASPP2 from stimulating p53 without targeting p53 for degradation

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Brn-3a/POU4F1 interacts with and differentially affects p73-mediated transcription

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Cdk5 mediates rotational force-induced brain injury

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Protein–protein interactions of ASPP2: an emerging therapeutic target

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Phenotypic Characteristics and Copy Number Variants in a Cohort of Colombian Patients with VACTERL Association

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Targeted splicing therapy: new strategies for colorectal cancer

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ATF4 Signaling in HIV-1 Infection: Viral Subversion of a Stress Response Transcription Factor

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A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53

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FHL2 interacts with iASPP and impacts the biological functions of leukemia cells

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Proteomic Analysis Uncovers Measles Virus Protein C Interaction With p65–iASPP Protein Complex

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Mechanisms of Apoptosis Resistance In Breast Cancer

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CCR5 blockade is well tolerated and induces changes in the tissue distribution of CCR5+ and CD25+ T cells in healthy, SIV‐uninfected rhesus macaques

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Truncated ASPP2 Drives Initiation and Progression of Invasive Lobular Carcinoma via Distinct Mechanisms

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ASPP2 Is Phosphorylated by CDK1 during Mitosis and Required for Pancreatic Cancer Cell Proliferation

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Downregulation of inhibitor of apoptosis-stimulating protein of p53 inhibits proliferation and promotes apoptosis of gastric cancer cells

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Knockout of ASPP2 promotes DEN-induced hepatocarcinogenesis via the NF-κB pathway in mice

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An N-terminal splice variant of human Stat5a that interacts with different transcription factors is the dominant form expressed in invasive ductal carcinoma

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Identification of TP53BP2 as a Novel Candidate Gene for Primary Open Angle Glaucoma by Whole Exome Sequencing in a Large Multiplex Family

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iASPPsv antagonizes apoptosis induced by chemotherapeutic agents in MCF-7 cells and mouse thymocytes.

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Cell type specific expression of the apoptosis stimulating protein (ASPP-2) in human tissues

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ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome

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Deep Phosphoproteomic Measurements Pinpointing Drug Induced Protective Mechanisms in Neuronal Cells

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Using TUNEL Assay to Quantitate p53-Induced Apoptosis in Mouse Tissues

Resnick‐Silverman, L. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1217-0_12 · Cited by 8

P53 and other Cell Cycle Regulators

Farid, N. R. (2006) · Kluwer Academic Publishers eBooks · doi:10.1007/1-4020-8107-3_8 · Cited by 8

DEC1 and MIC-1

Qian, Y., Jung, Y.-S., & Chen, X. (2012) · Cell Cycle · doi:10.4161/cc.21962 · Cited by 8

Apoptosis-stimulating protein of p53 (ASPP) participates in the regulation of apoptosis in Litopenaeus vannamei under ammonia-N and nitrite-N stress

Zhou, X., Zhuo, H., Lin, L., Zhang, Y., Li, J., Fu, S., Wu, G., Guo, C., & Liu, J. (2024) · Aquaculture Reports · doi:10.1016/j.aqrep.2024.102413 · Cited by 7

Predator: Predicting the Impact of Cancer Somatic Mutations on Protein-Protein Interactions

Berber, I., Erten, C., & Kazan, H. (2023) · IEEE Transactions on Computational Biology and Bioinformatics · doi:10.1109/tcbb.2023.3262119 · Cited by 7

Nucleostemin and ASPP2 expression is correlated with pituitary adenoma proliferation

Ma, L., Chen, Z. H., LI, X.-Y., Wang, X., Shou, J., & Fu, X. (2013) · Oncology Letters · doi:10.3892/ol.2013.1562 · Cited by 7

Chromosomal imbalances in successive moments of human bladder urothelial carcinoma

Pontes, M. G. N. E., Silveira, S. M., Filho, J. C. D. S. T., Rogatto, S. R., & de Camargo, J. L. V. (2011) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2011.05.015 · Cited by 7

The E3 ubiquitin ligase Itch and Yap1 have antagonistic roles in the regulation of ASPP2 protein stability

Gao, K., An, J., Zhang, Y., Jin, X., Ma, J., Peng, J., Tang, Y., Yu, L., Zhang, P., & Wang, C. (2014) · FEBS Letters · doi:10.1016/j.febslet.2014.11.030 · Cited by 7

Green Tea epigallocatechin-3-gallate Protects Against Oxidative Stress-Induced Nuclear Translocation of p53 and Apoptosis in Retinal Pigment Epithelial Cells, ARPE-19

Thichanpiang, P., Khanobdee, K., Kitiyanant, Y., & Wongprasert, K. (2013) · Journal of Agricultural Science · doi:10.5539/jas.v5n4p43 · Cited by 7

Functional consequences of inducible genetic elements from the p53 SOS response in a mammalian organ system

Guthrie, O. W. (2017) · Experimental Cell Research · doi:10.1016/j.yexcr.2017.08.010 · Cited by 7

Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein

Liu, R., Wang, X., Curtiss, C. M., Sheikh, M. S., & Huang, Y. K. (2020) · Cell Death and Differentiation · doi:10.1038/s41418-020-0549-5 · Cited by 7

Hzf and hCAS/CSE1L: making the right choice in p53-mediated tumour suppression

Ewings, K. E., & Ryan, K. (2007) · Cell Research · doi:10.1038/cr.2007.85 · Cited by 7

Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study

Xie, X.-F., Yang, Q. H., Chi, J., Yang, X.-Z., Wang, H., & Xu, G.-L. (2017) · 癌症：英文版 · doi:10.1186/s40880-016-0169-0 · Cited by 7

The Presence of a Short Form of p53 in Chicken Lymphoblastoid Cell Lines during Apoptosis

Takagi, M., Takeda, T., Asada, Y., Sugimoto, C., Onuma, M., & Ohashi, K. (2006) · Journal of Veterinary Medical Science · doi:10.1292/jvms.68.561 · Cited by 7

Moesin-ezrin-radixin-like protein merlin: Its conserved and distinct functions from those of ERM proteins

Senju, Y., & Hibino, E. (2022) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2022.184076 · Cited by 6

The Role of p53 in HIV Infection

Yaseen, M. M., Abuharfeil, N. M., & Darmani, H. (2023) · Current HIV/AIDS Reports · doi:10.1007/s11904-023-00684-8 · Cited by 7

iASPP: A Novel Protein Involved in Pituitary Tumorigenesis?

Pinto, E. M., Musolino, N. R. D. C., Cescato, V. Â. S., Soares, I. C., Wakamatsu, A., de Oliveira, E., Salgado, L. R., & Bronstein, M. D. (2010) · Frontiers of hormone research · doi:10.1159/000318496 · Cited by 6

A new strategy to resume the apoptosis activity of p53 in leukemia cell lines retaining wild-type p53

Liu, Z., Xin, H., Chen, J., Lü, X., Zhong, S., Gu, S.-Z., Wang, G. G., Liu, L., Cai, Y., & Hou, L. (2006) · Leukemia Research · doi:10.1016/j.leukres.2006.09.014 · Cited by 6

Effects of C heavy ion beam irradiation on the p53 signaling pathway in HepG2 liver cancer cells

Liu, K., Zhao, X., Gu, J., Wu, J., Zhang, H., & Li, Y. (2017) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmx096 · Cited by 6

Analysis of an artificially selected GS‐NS0 variant with increased resistance to apoptosis

Browne, S. M., & Al‐Rubeai, M. (2010) · Biotechnology and Bioengineering · doi:10.1002/bit.22994 · Cited by 6

Regulation of p53 DNA Binding

McKinney, K. M., & Prives, C. L. (2005) · Springer eBooks · doi:10.1007/978-1-4020-2922-6_2 · Cited by 6

The recently discovered Apoptosis Stimulating Proteins of p53

Sullivan, A., & Lu, X. (2013)

ASPP: a new family of oncogenes and tumour suppressor genes

Sullivan, A., & Lü, X. (2007) · British Journal of Cancer · doi:10.1038/sj.bjc.6603525 · Cited by 215

ASPPs and cancer

Trigiante, G., & Lü, X. (2006) · Nature reviews. Cancer · doi:10.1038/nrc1818 · Cited by 135

ASPP--Apoptotic specific regulator of p53.

Liu, Z.-J., Lu, X., & Zhong, S. (2005) · Biochimica et Biophysica Acta · doi:10.1016/j.bbcan.2005.08.002 · Cited by 26

ASPP1 and ASPP2: Common Activators of p53 Family Members

Bergamaschi, D., Samuels, Y., Jin, B., Duraisingham, S., Crook, T., & Lü, X. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.3.1341-1350.2004 · Cited by 229