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An mTOR anti-sense oligonucleotide decreases polycystic kidney disease in mice with a targeted mutation in Pkd2

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Nutrient Control of Yeast Gametogenesis Is Mediated by TORC1, PKA and Energy Availability

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LAS24/KOG1, a component of the TOR complex 1 (TORC1), is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast

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Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis

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Inhibition of mammalian target of rapamycin aggravates the respiratory burst defect of neutrophils from decompensated patients with cirrhosis

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TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal protein S6 in fission yeast

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Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy

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TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing

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Stb3 Plays a Role in the Glucose-Induced Transition from Quiescence to Growth in Saccharomyces cerevisiae

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Insulin delays the progression of Drosophila cells through G2/M by activating the dTOR/dRaptor complex

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Rapamycin Inhibits IGF-1 Stimulated Cell Motility through PP2A Pathway

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Cryo-EM insight into the structure of MTOR complex 1 and its interactions with Rheb and substrates

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Sphingolipid/Pkh1/2-TORC1/Sch9 Signaling Regulates Ribosome Biogenesis in Tunicamycin-Induced Stress Response in Yeast

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LST8 Regulates Cell Growth via Target-of-Rapamycin Complex 2 (TORC2)

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PRAS40: Target or modulator of mTORC1 signalling and insulin action?

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Mechanical activation of mammalian target of rapamycin pathway is required for cartilage development

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Signaling Pathways Involved in Antidepressant-Induced Cell Proliferation and Synaptic Plasticity

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Therapy for myeloproliferative neoplasms: when, which agent, and how?

Geyer, H. L., & Mesa, R. A. (2014) · Hematology · doi:10.1182/asheducation-2014.1.277 · Cited by 36

Phosphoinositide-Dependent Kinase 1 and mTORC2 Synergistically Maintain Postnatal Heart Growth and Heart Function in Mice

Zhao, X., Lu, S., Nie, J., Hu, X., Luo, W., Wu, X., Liu, H., Feng, Q., Chang, Z., Liu, Y., et al. (2014) · Molecular and Cellular Biology · doi:10.1128/mcb.00144-14 · Cited by 36

Rapamycin inhibits ox-LDL-induced inflammation in human endothelial cells in vitro by inhibiting the mTORC2/PKC/c-Fos pathway

Sun, J., Yin, X.-W., Liu, H.-H., Du, W.-X., Shi, L., Huang, Y., Wang, F., Liu, C., Cao, Y., & Zhang, Y. (2017) · Acta Pharmacologica Sinica · doi:10.1038/aps.2017.102 · Cited by 36

Targeting autophagy in liver cancer

Fazio, P. D., & Matrood, S. (2018) · Translational Gastroenterology and Hepatology · doi:10.21037/tgh.2018.06.09 · Cited by 36

Anticancer compound XL765 as PI3K/mTOR dual inhibitor: A structural insight into the inhibitory mechanism using computational approaches

Rehan, M. (2019) · PLoS ONE · doi:10.1371/journal.pone.0219180 · Cited by 36

Drug resistance in papillary RCC: from putative mechanisms to clinical practicalities

Brodziak, A., Sobczuk, P., Bartnik, E., Fiedorowicz, M., Porta, C., Szczylik, C. A., & Czarnecka, A. M. (2019) · Nature Reviews Urology · doi:10.1038/s41585-019-0233-z · Cited by 36

Nutrient Signaling and Lysosome Positioning Crosstalk Through a Multifunctional Protein, Folliculin

Garrido, N. D. M., & Aylett, C. H. S. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00108 · Cited by 37

Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt

Yu, Z., Chen, J., Takagi, E., Wang, F., Saha, B., Liu, X., Joubert, L., Gleason, C. E., Jin, M., Li, C., et al. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102288 · Cited by 39

TOR complex 2 is a master regulator of plasma membrane homeostasis

Thorner, J. W. (2022) · Biochemical Journal · doi:10.1042/bcj20220388 · Cited by 38

Role of phosphatidylinositol-3-kinase (PI3K) and the mammalian target of rapamycin (mTOR) signalling pathways in porcine reproductive and respiratory syndrome virus (PRRSV) replication

Pujhari, S. K., Kryworuchko, M., & Zakhartchouk, A. N. (2014) · Virus Research · doi:10.1016/j.virusres.2014.09.017 · Cited by 36

TORC2 Is Required to Maintain Genome Stability during S Phase in Fission Yeast

Schonbrun, M., Kolesnikov, M., Kupiec, M., & Weisman, R. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.464974 · Cited by 36

Mammalian target of rapamycin and head and neck squamous cell carcinoma

Liao, Y.-M., Kim, C., & Yen, Y. (2011) · Head & Neck Oncology · doi:10.1186/1758-3284-3-22 · Cited by 36

RES-529

Weinberg, M. A. (2016) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000000354 · Cited by 36

TOR-in(g) the Nucleus

Tsang, C. K., & Zheng, X.-F. (2007) · Cell Cycle · doi:10.4161/cc.6.1.3675 · Cited by 36

Trypanosome TOR as a major regulator of cell growth and autophagy

Barquilla, A., & Navarro, M. (2009) · Autophagy · doi:10.4161/auto.5.2.7591 · Cited by 36

Characterization of TOR complex 2 (TORC2) in "Saccharomyces cerevisiae"

Wullschleger, S. (2004) · edoc (University of Basel) · doi:10.5451/unibas-003679624

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Jacinto, E., Loewith, R., Schmidt, A., Lin, S., Rüegg, M. A., Hall, A., & Hall, M. N. (2004) · Nature Cell Biology · doi:10.1038/ncb1183 · Cited by 2,097

TOR signalling in yeast

Šimek, J. (2013) · Digital Repository (National Repository of Grey Literature)

Fission Yeast TOR and Rapamycin

Weisman, R. (2010) · The Enzymes · doi:10.1016/s1874-6047(10)27013-0 · Cited by 10

TORC2 downstream signaling in Saccharomyces cerevisiae

Eltschinger, S. (2015) · Archive ouverte UNIGE (University of Geneva) · doi:10.13097/archive-ouverte/unige:77570