The Origin and Nature of Life on Earth: The Emergence of the Fourth Geosphere

Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

WATSON, J. D., & CRICK, F. H. C. (1953) · Nature · doi:10.1038/171737a0 · Cited by 13,584 · see citing works

Information theory and statistical mechanics

Jaynes, E. T. (1957) · Physical Review · doi:10.1103/physrev.106.620 · Cited by 12,931 · see citing works

Life at low Reynolds number

Purcell, E. M. (1977) · American Journal of Physics · doi:10.1119/1.10903 · Cited by 4,360 · see citing works

Energy conservation in chemotrophic anaerobic bacteria

Thauer, R. K., Jungermann, K., & Decker, K. (1977) · Bacteriological Reviews · doi:10.1128/br.41.1.100-180.1977 · Cited by 4,146 · see citing works

XXIV. On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies. In a letter to Francis Baily, Esq. F. R. S. &c

Gompertz, B. (1825) · Philosophical Transactions of the Royal Society of London · doi:10.1098/rstl.1825.0026 · Cited by 3,816 · see citing works

A Production of Amino Acids Under Possible Primitive Earth Conditions

Miller, S. L. (1953) · Science · doi:10.1126/science.117.3046.528 · Cited by 3,522 · see citing works

CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS

WADDINGTON, C. H. (1942) · Nature · doi:10.1038/150563a0 · Cited by 3,255 · see citing works

How Many Species Are There on Earth and in the Ocean?

Mora, C., Tittensor, D. P., Adl, S., Simpson, A. G. B., & Worm, B. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1001127 · Cited by 3,045 · see citing works

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N., & Altman, S. (1983) · Cell · doi:10.1016/0092-8674(83)90117-4 · Cited by 2,684 · see citing works

Convection plumes in the lower mantle

MORGAN, W. J. (1971) · Nature · doi:10.1038/230042a0 · Cited by 2,565 · see citing works

Atmospheric Influence of Earth's Earliest Sulfur Cycle

Farquhar, J., Bao, H., & Thiemens, M. (2000) · Science · doi:10.1126/science.289.5480.756 · Cited by 1,805 · see citing works

Why Nature Chose Phosphates

Westheimer, F. H. (1987) · Science · doi:10.1126/science.2434996 · Cited by 1,711 · see citing works

Horizontal gene transfer in eukaryotic evolution

Keeling, P. J., & Palmer, J. D. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2386 · Cited by 1,355 · see citing works

The Cambrian Conundrum: Early Divergence and Later Ecological Success in the Early History of Animals

Erwin, D. H., Laflamme, M., Tweedt, S. M., Sperling, E. A., Pisani, D., & Peterson, K. J. (2011) · Science · doi:10.1126/science.1206375 · Cited by 1,336 · see citing works

A Serpentinite-Hosted Ecosystem: The Lost City Hydrothermal Field

Kelley, D. S., Karson, J. A., Früh-Green, G. L., Yoerger, D. R., Shank, T. M., Butterfield, D. A., Hayes, J. M., Schrenk, M. O., Olson, E. J., Proskurowski, G., et al. (2005) · Science · doi:10.1126/science.1102556 · Cited by 1,288 · see citing works

Before enzymes and templates: theory of surface metabolism

Wächtershäuser, G. (1988) · Microbiological Reviews · doi:10.1128/mmbr.52.4.452-484.1988 · Cited by 1,242 · see citing works

Gene Regulatory Networks and the Evolution of Animal Body Plans

Davidson, E. H., & Erwin, D. H. (2006) · Science · doi:10.1126/science.1113832 · Cited by 1,207 · see citing works

An off-axis hydrothermal vent field near the Mid-Atlantic Ridge at 30° N

Party, T. A.-6. S., Kelley, D. S., Karson, J. A., Blackman, D. K., Früh-Green, G. L., Butterfield, D. A., Lilley, M. D., Olson, E. J., Schrenk, M. O., Roe, K. K., et al. (2001) · Nature · doi:10.1038/35084000 · Cited by 1,168 · see citing works

On Chance and Necessity

Monod, J. (1974) · Studies in the Philosophy of Biology · doi:10.1007/978-1-349-01892-5_20 · Cited by 967 · see citing works

Philosophy and the practice of Bayesian statistics

Gelman, A., & Shalizi, C. R. (2013) · British Journal of Mathematical and Statistical Psychology · doi:10.1111/j.2044-8317.2011.02037.x · Cited by 825 · see citing works

Energy conservation via electron bifurcating ferredoxin reduction and proton/Na+ translocating ferredoxin oxidation

Buckel, W., & Thauer, R. K. (2013) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2012.07.002 · Cited by 797 · see citing works

Evolution of Photosynthesis

Hohmann-Marriott, M. F., & Blankenship, R. E. (2011) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042110-103811 · Cited by 744 · see citing works

Activated Acetic Acid by Carbon Fixation on (Fe,Ni)S Under Primordial Conditions

Huber, C., & Wächtershäuser, G. (1997) · Science · doi:10.1126/science.276.5310.245 · Cited by 714 · see citing works

Mineral evolution

Hazen, R. M., Papineau, D., Bleeker, W., Downs, R. T., Ferry, J. M., McCoy, T. J., Sverjensky, D. A., & Yang, H. (2008) · American Mineralogist · doi:10.2138/am.2008.2955 · Cited by 701 · see citing works

Self-Sustained Replication of an RNA Enzyme

Lincoln, T. A., & Joyce, G. F. (2009) · Science · doi:10.1126/science.1167856 · Cited by 670 · see citing works

Abiogenic Methane Formation and Isotopic Fractionation Under Hydrothermal Conditions

Horita, J., & Berndt, M. E. (1999) · Science · doi:10.1126/science.285.5430.1055 · Cited by 590 · see citing works

Linked magma ocean solidification and atmospheric growth for Earth and Mars

Elkins-Tanton, L. T. (2008) · Earth and Planetary Science Letters · doi:10.1016/j.epsl.2008.03.062 · Cited by 589 · see citing works

Priscoan (4.00–4.03 Ga) orthogneisses from northwestern Canada

Bowring, S. A., & Williams, I. S. (1999) · Contributions to Mineralogy and Petrology · doi:10.1007/s004100050465 · Cited by 568 · see citing works

The genetic code is one in a million

Freeland, S. J., & Hurst, L. D. (1998) · Journal of Molecular Evolution · doi:10.1007/pl00006381 · Cited by 563 · see citing works

Initiation and evolution of plate tectonics on Earth: Theories and observations

Korenaga, J. (2013) · Annual Review of Earth and Planetary Sciences · doi:10.1146/annurev-earth-050212-124208 · Cited by 533 · see citing works

Observation of wavelength‐sensitive mass‐independent sulfur isotope effects during SO₂ photolysis: Implications for the early atmosphere

Farquhar, J., Savarino, J., Airieau, S., & Thiemens, M. H. (2001) · Journal of Geophysical Research: Planets · doi:10.1029/2000je001437 · Cited by 518 · see citing works

Melting in an Archaean mantle plume: Heads it’s basalts, tails it’s komatiites

Campbell, I. H., Griffiths, R. W., & Hill, R. I. (1989) · Nature · doi:10.1038/339697a0 · Cited by 470 · see citing works

Bow ties, metabolism and disease

Csete, M., & Doyle, J. (2004) · Trends in biotechnology · doi:10.1016/j.tibtech.2004.07.007 · Cited by 468 · see citing works

The evolution of hierarchical gene regulatory networks

Erwin, D. H., & Davidson, E. H. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2499 · Cited by 454 · see citing works

The origin of membrane bioenergetics

Lane, N., & Martin, W. F. (2012) · Cell · doi:10.1016/j.cell.2012.11.050 · Cited by 452 · see citing works

The Iron-Hydrogenase of <i>Thermotoga maritima</i> Utilizes Ferredoxin and NADH Synergistically: a New Perspective on Anaerobic Hydrogen Production

Schut, G. J., & Adams, M. W. W. (2009) · Journal of Bacteriology · doi:10.1128/jb.01582-08 · Cited by 447 · see citing works

The anthropic principle and the structure of the physical world

Carr, B. J., & Rees, M. J. (1979) · Nature · doi:10.1038/278605a0 · Cited by 438 · see citing works

Evolution of Aminoacyl-tRNA Synthetases—Analysis of Unique Domain Architectures and Phylogenetic Trees Reveals a Complex History of Horizontal Gene Transfer Events

Wolf, Y. I., Aravind, L., Grishin, N. V., & Koonin, E. V. (1999) · Genome Research · doi:10.1101/gr.9.8.689 · Cited by 410 · see citing works

On the origin of genomes and cells within inorganic compartments

Koonin, E. V., & Martin, W. (2005) · Trends in Genetics · doi:10.1016/j.tig.2005.09.006 · Cited by 406 · see citing works

Synthesis of Purines under Possible Primitive Earth Conditions. I. Adenine from Hydrogen Cyanide

Oró, J., & Kimball, A. P. (1961) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(61)90033-9 · Cited by 406 · see citing works

Emergence of two types of terrestrial planet on solidification of magma ocean

Hamano, K., Abe, Y., & Genda, H. (2013) · Nature · doi:10.1038/nature12163 · Cited by 402 · see citing works

Compositional genomes: Prebiotic information transfer in mutually catalytic noncovalent assemblies

Segré, D., Ben-Eli, D., & Lancet, D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.8.4112 · Cited by 398 · see citing works

The Early Faint Sun Paradox: Organic Shielding of Ultraviolet-Labile Greenhouse Gases

Sagan, C., & Chyba, C. (1997) · Science · doi:10.1126/science.276.5316.1217 · Cited by 396 · see citing works

Climatic consequences of very high carbon dioxide levels in the earth’s early atmosphere

Kasting, J. F., & Ackerman, T. P. (1986) · Science · doi:10.1126/science.11539665 · Cited by 391 · see citing works

Spontaneous network formation among cooperative RNA replicators

Vaidya, N., Manapat, M. L., Chen, I. A., Xulvi-Brunet, R., Hayden, E. J., & Lehman, N. (2012) · Nature · doi:10.1038/nature11549 · Cited by 383 · see citing works

Pyrite Formation, the First Energy Source for Life: a Hypothesis

Wächtershäuser, G. (1988) · Systematic and Applied Microbiology · doi:10.1016/s0723-2020(88)80001-8 · Cited by 374 · see citing works

Late Archean Biospheric Oxygenation and Atmospheric Evolution

Kaufman, A. J., Johnston, D. T., Farquhar, J., Masterson, A. L., Lyons, T. W., Bates, S., Anbar, A. D., Arnold, G. L., Garvin, J., & Buick, R. (2007) · Science · doi:10.1126/science.1138700 · Cited by 374 · see citing works

Elevated concentrations of formate, acetate and dissolved organic carbon found at the lost City hydrothermal field

Lang, S. Q., Butterfield, D. A., Schulte, M., Kelley, D. S., & Lilley, M. D. (2010) · Geochimica et Cosmochimica Acta · doi:10.1016/j.gca.2009.10.045 · Cited by 368 · see citing works

The faint young Sun problem

Feulner, G. (2012) · Reviews of Geophysics · doi:10.1029/2011rg000375 · Cited by 338 · see citing works

A quantitative measure of error minimization in the genetic code

Haig, D., & Hurst, L. D. (1991) · Journal of Molecular Evolution · doi:10.1007/bf02103132 · Cited by 337 · see citing works

Serpentinization and its implications for life on the early earth and Mars

Schulte, M., Blake, D., Hoehler, T., & McCollom, T. (2006) · Astrobiology · doi:10.1089/ast.2006.6.364 · Cited by 321 · see citing works

The Drive to Life on Wet and Icy Worlds

Russell, M. J., Barge, L. M., Bhartia, R., Bocanegra, D., Bracher, P. J., Branscomb, E., Kidd, R., McGlynn, S., Meier, D. H., Nitschke, W., et al. (2014) · Astrobiology · doi:10.1089/ast.2013.1110 · Cited by 288 · see citing works

Lipid vesicles as possible intermediates in the origin of life

Luisi, P. L., Walde, P., & Oberholzer, T. (1999) · Current Opinion in Colloid &amp; Interface Science · doi:10.1016/s1359-0294(99)00012-6 · Cited by 287 · see citing works

Laboratory Simulations of Abiotic Hydrocarbon Formation in Earth's Deep Subsurface

McCollom, T. M. (2013) · Reviews in Mineralogy and Geochemistry · doi:10.2138/rmg.2013.75.15 · Cited by 285 · see citing works

Photochemistry of methane and the formation of hydrocyanic acid (HCN) in the Earth's early atmosphere

Zahnle, K. J. (1986) · Journal of Geophysical Research: Atmospheres · doi:10.1029/jd091id02p02819 · Cited by 276 · see citing works

An Ancient Pathway Combining Carbon Dioxide Fixation with the Generation and Utilization of a Sodium Ion Gradient for ATP Synthesis

Poehlein, A., Schmidt, S., Kaster, A.-K., Goenrich, M., Vollmers, J., Thürmer, A., Bertsch, J., Schuchmann, K., Voigt, B., Hecker, M., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033439 · Cited by 274 · see citing works

The molecular basis for the genetic code.

Woese, C. R., Dugre, D. H., Saxinger, W. C., & Dugre, S. A. (1966) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.55.4.966 · Cited by 270 · see citing works

Compilation and Network Analyses of Cambrian Food Webs

Dunne, J. A., Williams, R. J., Martinez, N. D., Wood, R. A., & Erwin, D. H. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060102 · Cited by 269 · see citing works

Deducing patterns of fluid flow and mixing within the TAG active hydrothermal mound using mineralogical and geochemical data.

Tivey, M. K., Humphris, S. E., Thompson, G., Hannington, M. D., & Rona, P. A. (1995) · Journal of Geophysical Research: Solid Earth · doi:10.1029/95jb00610 · Cited by 268 · see citing works

Origin and evolution of the ribosome

Fox, G. E. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003483 · Cited by 258 · see citing works

Aqueous Corrosion of Phosphide Minerals from Iron Meteorites: A Highly Reactive Source of Prebiotic Phosphorus on the Surface of the Early Earth

Pasek, M. A., & Lauretta, D. S. (2005) · Astrobiology · doi:10.1089/ast.2005.5.515 · Cited by 251 · see citing works

The Triplet Code From First Principles

Trifonov, E. N. (2004) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2004.10506975 · Cited by 246 · see citing works

Abiotic nitrogen reduction on the early Earth

Brandes, J. A., Boctor, N. Z., Cody, G. D., Cooper, B. A., Hazen, R. M., & Yoder, H. S. (1998) · Nature · doi:10.1038/26450 · Cited by 237 · see citing works

Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics

Pascal, R., Pross, A., & Sutherland, J. D. (2013) · Open Biology · doi:10.1098/rsob.130156 · Cited by 228 · see citing works

A hierarchical model for evolution of 23S ribosomal RNA

Bokov, K., & Steinberg, S. V. (2009) · Nature · doi:10.1038/nature07749 · Cited by 228 · see citing works

Hydrothermal Fe fluxes during the Precambrian: Effect of low oceanic sulfate concentrations and low hydrostatic pressure on the composition of black smokers

Kump, L. R., & Seyfried, W. E. (2005) · Earth and Planetary Science Letters · doi:10.1016/j.epsl.2005.04.040 · Cited by 221 · see citing works

A Reverse KREBS Cycle in Photosynthesis: Consensus at Last

Buchanan, B. B., & Arnon, D. I. (1990) · Photosynthesis Research · doi:10.1007/bf00032643 · Cited by 221 · see citing works

Geodiversity of hydrothermal processes along the Mid-Atlantic Ridge and ultramafic-hosted mineralization: A new type of oceanic Cu-Zn-Co-Au volcanogenic massive sulfide deposit

Fouquet, Y., Cambon, P., Etoubleau, J., Charlou, J. L., Ondréas, H., Barriga, F. J. A. S., Cherkashov, G., Semkova, T., Poroshina, I., Bohn, M., et al. (2010) · Geophysical Monograph Series · doi:10.1029/2008gm000746 · Cited by 216 · see citing works

The origin of the RNA world: Co-evolution of genes and metabolism

Copley, S. D., Smith, E., & Morowitz, H. J. (2007) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2007.08.001 · Cited by 184 · see citing works

Co-evolution of primordial membranes and membrane proteins

Mulkidjanian, A. Y., Galperin, M. Y., & Koonin, E. V. (2009) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2009.01.005 · Cited by 169 · see citing works

Evolutionary primacy of sodium bioenergetics

Mulkidjanian, A. Y., Galperin, M. Y., Makarova, K. S., Wolf, Y. I., & Koonin, E. V. (2008) · Biology Direct · doi:10.1186/1745-6150-3-13 · Cited by 163 · see citing works

Submarine hot springs and the origin of life

RUSSELL, M. J., HALL, A. J., CAIRNS-SMITH, A. G., & BRATERMAN, P. S. (1988) · Nature · doi:10.1038/336117a0 · Cited by 161 · see citing works

Photochemistry of methane in the Earth's early atmosphere

Kasting, J. F., Zahnle, K. J., & Walker, J. C. G. (1983) · Precambrian Research · doi:10.1016/0301-9268(83)90069-4 · Cited by 150 · see citing works

Formation of H2 and CH4by weathering of olivine at temperatures between 30 and 70°C

Neubeck, A., Duc, N. T., Bastviken, D., Crill, P., & Holm, N. G. (2011) · Geochemical Transactions · doi:10.1186/1467-4866-12-6 · Cited by 135 · see citing works

Nonenzymatic, template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3′-5′ phosphodiester bonds

Rohatgi, R., Bartel, D. P., & Szostak, J. W. (1996) · Journal of the American Chemical Society · doi:10.1021/ja9537134 · Cited by 134 · see citing works

Mineral Evolution: Mineralogy in the Fourth Dimension

Hazen, R. M., & Ferry, J. M. (2010) · Elements · doi:10.2113/gselements.6.1.9 · Cited by 133 · see citing works

Hydrothermal Focusing of Chemical and Chemiosmotic Energy, Supported by Delivery of Catalytic Fe, Ni, Mo/W, Co, S and Se, Forced Life to Emerge

Nitschke, W., & Russell, M. J. (2009) · Journal of Molecular Evolution · doi:10.1007/s00239-009-9289-3 · Cited by 132 · see citing works

Plausible origins of homochirality in the amino acid catalyzed neogenesis of carbohydrates

Córdova, A., Engqvist, M., Ibrahem, I., Casas, J., & Sundén, H. (2005) · Chem. Commun. · doi:10.1039/b500589b · Cited by 127 · see citing works

Nucleobases bind to and stabilize aggregates of a prebiotic amphiphile, providing a viable mechanism for the emergence of protocells

Black, R. A., Blosser, M. C., Stottrup, B. L., Tavakley, R., Deamer, D. W., & Keller, S. L. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1300963110 · Cited by 123 · see citing works

On a Hypothetical Generational Relationship between HCN and Constituents of the Reductive Citric Acid Cycle

Eschenmoser, A. (2007) · Chemistry &amp; Biodiversity · doi:10.1002/cbdv.200790050 · Cited by 115 · see citing works

Synthesis of 35–40 mers of RNA oligomers from unblocked monomers. A simple approach to the RNA world

Huang, W., & Ferris, J. P. (2003) · Chem. Commun. · doi:10.1039/b303134a · Cited by 110 · see citing works

Hydrogen, metals, bifurcating electrons, and proton gradients: The early evolution of biological energy conservation

Martin, W. F. (2012) · FEBS Letters · doi:10.1016/j.febslet.2011.09.031 · Cited by 108 · see citing works

Biochemical fossils of the ancient transition from geoenergetics to bioenergetics in prokaryotic one carbon compound metabolism

Sousa, F. L., & Martin, W. F. (2014) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2014.02.001 · Cited by 100 · see citing works

Generation of oligonucleotides under hydrothermal conditions by non-enzymatic polymerization

DeGuzman, V., Vercoutere, W., Shenasa, H., & Deamer, D. (2014) · Journal of Molecular Evolution · doi:10.1007/s00239-014-9623-2 · Cited by 99 · see citing works

Out of fuzzy chemistry: from prebiotic chemistry to metabolic networks

Peretó, J. (2012) · Chemical Society Reviews · doi:10.1039/c2cs35054h · Cited by 96 · see citing works

The Molecular Roots of Compositional Inheritance

SEGRÉ, D., SHENHAV, B., KAFRI, R., & LANCET, D. (2001) · Journal of Theoretical Biology · doi:10.1006/jtbi.2001.2440 · Cited by 82 · see citing works

Universal Sequence Replication, Reversible Polymerization and Early Functional Biopolymers: A Model for the Initiation of Prebiotic Sequence Evolution

Walker, S. I., Grover, M. A., & Hud, N. V. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034166 · Cited by 70 · see citing works

Navigating the Chemical Space of HCN Polymerization and Hydrolysis: Guiding Graph Grammars by Mass Spectrometry Data

Andersen, J., Andersen, T., Flamm, C., Hanczyc, M., Merkle, D., & Stadler, P. (2013) · Entropy · doi:10.3390/e15104066 · Cited by 43 · see citing works

The basic reproductive ratio of life

Manapat, M. L., Chen, I. A., & Nowak, M. A. (2010) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2009.12.020 · Cited by 19 · see citing works

Symmetry and Collective Fluctuations in Evolutionary Games

Smith, E., & Krishnamurthy, S. (2015) · doi:10.1088/978-0-7503-1137-3 · Cited by 18 · see citing works

Nonenzymatic Metabolic Reactions and Life’s Origins

Muchowska, K. B., Varma, S. J., & Moran, J. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00191 · Cited by 317 · see citing works

Native iron reduces CO2 to intermediates and end-products of the acetyl-CoA pathway

Varma, S. J., Muchowska, K. B., Chatelain, P., & Moran, J. (2018) · Nature Ecology &amp; Evolution · doi:10.1038/s41559-018-0542-2 · Cited by 235 · see citing works

Metals promote sequences of the reverse Krebs cycle

Muchowska, K. B., Varma, S. J., Chevallot-Beroux, E., Lethuillier-Karl, L., Li, G., & Moran, J. (2017) · Nature Ecology &amp; Evolution · doi:10.1038/s41559-017-0311-7 · Cited by 228 · see citing works

Remnants of an Ancient Metabolism without Phosphate

Goldford, J. E., Hartman, H., Smith, T. F., & Segrè, D. (2017) · Cell · doi:10.1016/j.cell.2017.02.001 · Cited by 226 · see citing works

Exoplanet Biosignatures: A Framework for Their Assessment

Catling, D. C., Krissansen-Totton, J., Kiang, N. Y., Crisp, D., Robinson, T. D., DasSarma, S., Rushby, A. J., Del Genio, A., Bains, W., & Domagal-Goldman, S. (2018) · Astrobiology · doi:10.1089/ast.2017.1737 · Cited by 225 · see citing works

Membraneless polyester microdroplets as primordial compartments at the origins of life

Jia, T. Z., Chandru, K., Hongo, Y., Afrin, R., Usui, T., Myojo, K., & Cleaves, H. J. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1902336116 · Cited by 132 · see citing works

First principles in the life sciences: the free-energy principle, organicism, and mechanism

Colombo, M., & Wright, C. (2021) · Synthese · doi:10.1007/s11229-018-01932-w · Cited by 101 · see citing works

Origins of life: a problem for physics, a key issues review

Walker, S. I. (2017) · Reports on Progress in Physics · doi:10.1088/1361-6633/aa7804 · Cited by 94 · see citing works

Acetyl Phosphate as a Primordial Energy Currency at the Origin of Life

Whicher, A., Camprubi, E., Pinna, S., Herschy, B., & Lane, N. (2018) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-018-9555-8 · Cited by 81 · see citing works

Defining Lyfe in the Universe: From Three Privileged Functions to Four Pillars

Bartlett, S., & Wong, M. L. (2020) · Life · doi:10.3390/life10040042 · Cited by 77 · see citing works

How causal analysis can reveal autonomy in models of biological systems

Marshall, W., Kim, H., Walker, S. I., Tononi, G., & Albantakis, L. (2017) · Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences · doi:10.1098/rsta.2016.0358 · Cited by 64 · see citing works

Life as a guide to prebiotic nucleotide synthesis

Harrison, S. A., & Lane, N. (2018) · Nature Communications · doi:10.1038/s41467-018-07220-y · Cited by 63 · see citing works

Emergence of homochirality in large molecular systems

Laurent, G., Lacoste, D., & Gaspard, P. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2012741118 · Cited by 55 · see citing works

Hadean Earth

Harrison, T. M. (2020) · doi:10.1007/978-3-030-46687-9 · Cited by 53 · see citing works

The Origins of Life: The Managed-Metabolism Hypothesis

Stewart, J. E. (2019) · Foundations of Science · doi:10.1007/s10699-018-9563-1 · Cited by 44 · see citing works

Re-conceptualizing the origins of life

Walker, S. I., Packard, N., & Cody, G. D. (2017) · Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences · doi:10.1098/rsta.2016.0337 · Cited by 44 · see citing works

On the evolution of coenzyme biosynthesis

Kirschning, A. (2022) · Natural Product Reports · doi:10.1039/d2np00037g · Cited by 37 · see citing works

Hidden Concepts in the History and Philosophy of Origins-of-Life Studies: A Workshop Report

Mariscal, C., Barahona, A., Aubert-Kato, N., Aydinoglu, A. U., Bartlett, S., Cárdenas, M. L., Chandru, K., Cleland, C., Cocanougher, B. T., Comfort, N., et al. (2019) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-019-09580-x · Cited by 36 · see citing works

Fundamental constraints to the logic of living systems

Solé, R., Kempes, C. P., Corominas-Murtra, B., De Domenico, M., Kolchinsky, A., Lachmann, M., Libby, E., Saavedra, S., Smith, E., & Wolpert, D. (2024) · Interface Focus · doi:10.1098/rsfs.2024.0010 · Cited by 34 · see citing works

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Lim, R. W. J., & Fahrenbach, A. C. (2020) · Pure and Applied Chemistry · doi:10.1515/pac-2020-0805 · Cited by 8 · see citing works